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International Journal of Radiation Biology Volume 79, 2003 - Issue 7
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Editorial

Repopulation during fractionated radiotherapy: much has been learned, even more is open

M. Baumann Clinic of Radiation OncologyCorrespondence[email protected]‐dresden.de
,
W. Dörr Experimental Centre, Medical Faculty Carl Gustav Carus, University of Technology Dresden, D‐01307 Dresden Germany
,
C. Petersen Clinic of Radiation Oncology
&
M. Krause Experimental Centre, Medical Faculty Carl Gustav Carus, University of Technology Dresden, D‐01307 Dresden Germany
Pages 465-467 | Published online: 03 Jul 2009

References

  • BAUMANN, M., BENTZEN, S. M., DORA, W., JOINER, M. C., SAUNDERS, M., TANNOCKE, I. F. and THAMES, H. D., 2001, The translational research chain: is it delivering the goods? International Journal of Radiation Oncology Biology Physics, 49, 345–351.
  • BAUMANN, M., LIERTZ, C., BAISCH, H., WIEGEL, T., LORENZEN, J. and ARPS, H., 1994, Impact of overall treatment time of fractionated irradiation on local control of human FaDu squamous cell carcinoma in nude mice. Radiotherapy and Oncology, 32, 137–143.
  • BAUMANN, M., SAUNDERS, M. and JOINER, M. C., 2002, Modified fractionation. In G. G. Steel (ed.), Basic Clinical Radiobiology (London: Arnold).
  • BECK-BORNHOLDT, H. P., OMNICZYNSKI, M., THEIS, E., VOGLER, H. and WtIRSCHMIDT, F., 1991, Influence of treatment time on the response of rat rhabdomyosarcoma R1H to fractionated irradiation. Acta Oncologica, 30, 57–63.
  • BuscHKE, F., 1963, Conclusion of the symposium on protraction and fractionation. American Journal of Roentgenology, 91, 61.
  • DORA, W. and HENDRY, J. H., 2001, Consequential late effects in normal tissues. Radiotherapy and Oncology, 61, 223–231.
  • Erns, F., 1969, Dose, time and fractionation: a clinical hypothesis. Clinical Radiology, 20, l–7.
  • HANSEN, 0., OVERGAARD, J., HANSEN, H. S., OVERGAARD, M., HOYER, M., JORGEN, K. E., BASTHOLT, L. and BERTHELSEN, A., 1997, Importance of overall treatment time for the outcome of radiotherapy of advanced head and neck carcinoma: dependency on tumor differentiation. Radiotherapy and Oncology, 43, 47–51.
  • MACIEJEWSKI, B., PREUSS-BAYER, G. and TRoTr, K. R., 1983, The influence of the number of fractions and of overall treatment time on local control and late complication rate in squamous cell carcinoma of the larynx. International Journal of Radiation Oncology Biology Physics, 9, 321–328.
  • PETERSEN, C., ZIPS, D., KRAUSE, M., SCHONE, K., EICHELER, W., HOINKIS, C., THAMES, H. D. and BAUMANN, M., 2001, Repopulation of FaDu human squamous cell carcinoma during fractionated radiotherapy correlates with reoxy-genation. International Journal of Radiation Oncology Biology Physics, 51, 483–493.
  • SPEKE, A. K. and HILL, R. P., 1995, Repopulation kinetics during fractionated irradiation and the relationship to the potential doubling time, Tpot. International Journal of Radiation Oncology Biology Physics, 31, 847–856.
  • SUIT, H. D., HOWES, A. E. and HUNTER, N., 1977, Dependence of response of a C3H mammary carcinoma to fractionated irradiation on fractionation number and intertreatment interval. Radiation Research, 72, 440–454.
  • THAMES, H. D., JR, PETERS, L. J., WITHERS, H. R. and FLETCHER, G. H., 1983, Accelerated fractionation vs hyperfraction-ation: rationales for several treatments per day. International Journal of Radiation Oncology Biology Physics, 9, 127–138.
  • THAMES, H. D., RUIFROK, A. C., MrLAs, L., HUNTER, N., MASOW, K. A., TERRY, N. H. and WHITE, R. A., 1996, Accelerated repopulation during fractionated irradiation of a murine ovarian carcinoma: downregulation of apoptosis as a possible mechanism. International Journal of Radiation Oncology Biology Physics, 35, 951–962.
  • TROTT, K. R. and KUMMERMEHR, J., 1991, Rapid repopulation in radiotherapy: a debate on mechanism. Accelerated repopulation in tumours and normal tissues. Radiotherapy and Oncology, 22, 159–160.
  • TROTT, K. R. and KUMMERMEITR, J., 1993, The time factor and repopulation in tumors and normal tissues. Seminars in Radiation Oncology, 3, 115–125.
  • WITHERS, H. R., 1975, The four R's of radiotherapy. In J. T. Lett and H. Adler (eds), Advances in Radiation Biology (New York: Academic Press), 5, pp. 241–247.
  • WITHERS, H. R., TAYLOR, J. M. and MACIEJEWSKI, B., 1988, The hazard of accelerated tumor clonogen repopulation during radiotherapy. Acta Oncologica, 27, 131–146.

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