Morphological and molecular alterations at the junctional complex in irradiated human colon adenocarcinoma cells, Caco-2

References

• Akimoto T, Mitsuhashi N, Saito Y, Ebara T, Niibe H. Effect of radiation on the expression of E-cadherin and alpha-catenin and invasive capacity in human lung cancer cell line in vitro. International Journal of Radiation Oncology, Biology Physics 1998; 41: 1171–1176
   PubMedGoogle Scholar
• Balda M S, Matter K. Tight junction. Journal of Cell Biology 1998; 111: 541–547
   Google Scholar
• Barbosa L A, Goto-Silva L, Redondo P A, Oliveira S, Montesano G, De Souza W, Morgado-Díaz J M. TPA-induced signal transduction: A link between PKC and EGFR signaling modulates the assembly of intercellular junctions in Caco-2 cells. Cell and Tissue Research 2003; 312: 319–331
   PubMedGoogle Scholar
• Birgisson H, Pahlman L, Gunnarsson U, Glimelius B. Occurrence of second cancers in patients treated with radiotherapy for rectal cancer. Journal of Clinical Oncology 2005; 23: 6126–6131
   PubMedGoogle Scholar
• Clarke H, Soler A P, Mullin J M. Protein kinase C activation leads to dephosphorylation of occludin and tight junction permeability increase in LLC-PK1 epithelial cells sheets. Journal of Cell Science 2000; 113: 3187–3196
   PubMed Web of Science ®Google Scholar
• Colegio O R, Van Itallie C M, McCrea H J, Rahner C, Anderson J M. Claudins create charge-selective channels in the paracellular pathway between epithelial cells. American Journal of Physiology 2002; 283: C142–C147
   PubMed Web of Science ®Google Scholar
• Dent P, Reardon D B, Park J S, Bowers G, Logsdon C, Valerie K, Schmidt-Ullrich R. Radiation-induced release of TGF-α activates the EGFR and MAPK pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced cell death. Molecular Biology of the Cell 1999; 10: 2493–2506
   PubMed Web of Science ®Google Scholar
• Dhawan P, Singh A B, Deane N G, No Y, Shiou S R, Schmidt C, Neff J, Washington M K, Beauchamp R D. Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer. Journal of Clinical Investigation 2005; 115: 1765–1776
   PubMed Web of Science ®Google Scholar
• Dublineau I, Lebrun F, Grison S, Griffiths N M. Functional and structural alterations of epithelial barrier properties of rat ileum following X-irradiation. Canadian Journal of Physiology and Pharmacology 2004; 82: 84–93
   PubMed Web of Science ®Google Scholar
• Erez N, Bershadsky A, Geiger B. Signaling from adherens-type junctions. European Journal of Cell Biology 2005; 84: 235–244
   PubMedGoogle Scholar
• Fanning A S, Jameson B J, Jesaitis L A, Anderson J M. The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton. Journal of Biological Chemistry 1998; 173: 29745–29753
   Google Scholar
• Feldman G J, Mullin J M, Ryan M P. Occludin: Structure, function and regulation. Advanced Drug Delivery Reviews 2005; 57: 883–917
   PubMed Web of Science ®Google Scholar
• Furuse M, Hirase T, Itoh M, Nagafuchi A, Yonemura S, Tsukita S. Occludin: A novel integral membrane protein localizing at tight junctions. Journal of Cell Biology 1993; 123: 1777–1788
   PubMed Web of Science ®Google Scholar
• Furuse M, Sasaki H, Fujimoto K, Tsukita S. A single gene product, claudin-1 or -2, reconstitutes tight junction strands and recruits occludin in fibroblasts. Journal of Cell Biology 1998; 143: 391–401
   PubMed Web of Science ®Google Scholar
• Gonzalez-Mariscal L, Islas S, Contreras R G, Garcia-Villegas M R, Betanzos A, Veja J, Diaz-Quinonez A, Martin-Orozco N, Ortiz-Navarrete V, Cereijido M, Valdes J. Molecular characterization of the tight junction protein ZO-1 in MDCK cells. Experimental Cell Research 1999; 248: 97–109
   PubMed Web of Science ®Google Scholar
• Gooding J M, Yap K L, Ikura M. The cadherin-catenin complex as a focal point of cell adhesion and signalling: New insights from three-dimensional structures. Bioessays 2004; 26: 497–511
   PubMed Web of Science ®Google Scholar
• Gottardi C J, Arpin M, Fanning A S, Louvard D. The junction-associated protein, zonula occludens-1, localizes to the nucleus before the maturation and during the remodeling of cell-cell contacts. Proceedings of the National Academy of Sciences of the United States of America 1996; 93: 10779–10784
   PubMed Web of Science ®Google Scholar
• Haskins J, Gu L, Wittchen E S, Hibbard J, Stevenson B R. ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin. Journal of Cell Biology 1998; 141: 199–208
   PubMedGoogle Scholar
• Islas S, Veja J, Ponce L, Gonzalez-Mariscal L. Nuclear localization of the tight junction protein ZO-2 in epithelial cells. Experimental Cell Research 2002; 274: 138–148
   PubMedGoogle Scholar
• Kemler R. From cadherins to catenins: Cytoplasmic protein interactions and regulation of cell adhesion. Trends in Genetics 1993; 9: 317–321
   PubMed Web of Science ®Google Scholar
• Laemmli U K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680–685
   PubMed Web of Science ®Google Scholar
• Li Z, Hosoi Y, Cai K, Tanno Y, Matsumoto Y, Enomoto A, Morita A, Nakagawa K, Miyagawa K. Src tyrosine kinase inhibitor PP2 suppresses ERK1/2 activation and epidermal growth factor receptor transactivation by X-irradiation. Biochemical and biophysical research communications 2006; 341: 363–368
   PubMed Web of Science ®Google Scholar
• Liang K, Ang K K, Milas L, Hunter N, Fan Z. The epidermal growth factor receptor mediates radioresistance. International Journal of Radiation Oncology, Biology Physics 2003; 57: 246–254
   PubMed Web of Science ®Google Scholar
• Madara J L. Regulation of the movement of solutes across tight junctions. Annual Review of Physiology 1998; 60: 143–159
   PubMed Web of Science ®Google Scholar
• Martin-Padura I, Lostaglio S, Schneemann M, Williams L, Romano M, Fruscella P, Panzeri C, Stoppacciaro A, Ruco L, Villa A, Simmons D, Dejana E. Junctional adhesion molecule, a novel member of immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration. Journal of Cell Biology 1998; 142: 117–127
   PubMed Web of Science ®Google Scholar
• Matter K, Balda M S. Signalling to and from tight junctions. Nature Reviews Molecular Cell Biology 2003; 4: 225–236
   PubMed Web of Science ®Google Scholar
• McCarthy K M, Francis S A, McCormack J M, Lai J, Rogers R A, Skare I B, Lynch R D, Schneeberger E E. Inducible expression of claudin-1-myc but not occludin-VSV-G results in aberrant tight junction strand formation in MDCK cells. Journal of Cell Science 2000; 113: 3387–3398
   PubMed Web of Science ®Google Scholar
• Midgley R, Kerr D. Colorectal cancer. Lancet 1999; 353: 391–399
   PubMed Web of Science ®Google Scholar
• Mitic L L, Van Itallie C M, Anderson J M. Molecular physiology and pathophysiology of tight junctions I. Tight junction structure and function: lessons from mutant animals and proteins. American Journal of Physiology. Gastrointestinal and Liver Physiology 2000; 279: G250–G254
   PubMed Web of Science ®Google Scholar
• Morgado-Díaz J A, De Souza W. Evidence that increased tyrosine phosphorylation causes disassembly of adherens junctions but does not perturb paracellular permeability in Caco-2 cells. Tissue and Cell 2001; 33: 500–513
   PubMedGoogle Scholar
• Musch M W, Walsh-Reitz M M, Chang E B. Roles of ZO-1, occludin, and actin in oxidant-induced barrier disruption. American Journal of Physiology. Gastrointestinal and Liver Physiology 2006; 290: G222–G321
   PubMed Web of Science ®Google Scholar
• Nejdfors P, Ekelund M, Westrom B R, Willen R, Jeppsson B. Intestinal permeability in humans is increased after radiation therapy. Diseases of the Colon and Rectum 2000; 43: 1582–1588
   PubMed Web of Science ®Google Scholar
• Nelson W J. Adaptation of core mechanisms to generate cell polarity. Nature 2003; 422: 766–774
   PubMed Web of Science ®Google Scholar
• Nyati M K, Maheshwari D, Hanasoge S, Sreekumar A, Rynkiewicz S D, Chinnaiyan A M, Leopold W R, Ethier S P, Lawrence T S. Radiosensitization by Pan ErbB Inhibitor CI-1033 in vitro and in vivo. Clinical Cancer Research 2004; 10: 691–700
   PubMed Web of Science ®Google Scholar
• Oehler C, Ciernik I F. Radiation therapy and combined modality treatment of gastrointestinal carcinomas. Cancer Treatment Reviews 2006; 32: 119–138
   PubMed Web of Science ®Google Scholar
• Oliveira S S, Oliveira I M, De Souza W, Morgado-Díaz J A. Claudins upregulation in human colorectal cancer. FEBS Letters 2005; 579: 6179–6185
   PubMedGoogle Scholar
• Park C C, Henshall-Powell R L, Erickson A C, Talhouk R, Parvin B, Bissel M J, Barcellos-Hoff M H. Ionizing radiation induces heritable disruption of epithelial cell interactions. Proceedings of the National Academy of Sciences of the United States of America 2003; 100: 10728–10733
   PubMed Web of Science ®Google Scholar
• Perez-Moreno M, Jamora C, Fuchs E. Sticky business: Orchestrating cellular signals at adherens junctions. Cell 2003; 112: 535–548
   PubMed Web of Science ®Google Scholar
• Sakakibara A, Furuse M, Saitou M, Ando-Akastsuka Y, Tsukita S. Possible involvement of phosphorylation on tight junction formation. Journal of cell Biology 1997; 137: 1393–1341
   PubMed Web of Science ®Google Scholar
• Somosy Z, Sass M, Bógnar G, Kovács J, Köteles G J. X-irradiation-induced disorganization of cytoskeleton filaments and cell contacts in HT-29 cells. Scanning Microscopy 1995; 9: 763–772
   PubMedGoogle Scholar
• Somosy Z. Radiation response of cell organelles. Micron 2000; 31: 165–181
   PubMed Web of Science ®Google Scholar
• Somosy Z, Bógnar G, Thuróczy G, Köteles G J. Biological responses of tight junction to ionizing radiation and electromagnetic field exposition. Cellular and Molecular Biology 2002; 48: 571–575
   PubMedGoogle Scholar
• Speake W J, Dean R A, Kumar A, Morris T M, Scholefield J H, Watson S A. Radiation induced MMP expression from rectal cancer is short lived but contributes to in vitro invasion. European Journal of Surgical Oncology 2005; 31: 869–874
   PubMed Web of Science ®Google Scholar
• Suzuki K, Kodama S, Watanabe M. Extremely low-dose ionizing radiation causes activation of mitogen-activated protein kinase pathway and enhances proliferation of normal human diploid cells. Cancer Research 2001; 61: 5396–5401
   PubMed Web of Science ®Google Scholar
• Taddei M L, Chiarugi P, Cirri P, Buricchi F, Fiaschi T, Giannoni E, Talini D, Cozzi G, Formigli L, Raugei G, Ramponi G. Beta-catenin interacts with low-molecular-weight protein tyrosine phosphatase leading to cadherin-mediated cell-cell adhesion increase. Cancer Research 2002; 62: 6489–6499
   PubMed Web of Science ®Google Scholar
• Takai Y, Nakanishi H. Nectin and afadin: Novel organizers of intercellular junctions. Journal of Cell Science 2003; 116: 17–27
   PubMed Web of Science ®Google Scholar
• Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proceedings of the National Academy of Sciences of the United States of America 1979; 76: 4350–4354
   PubMed Web of Science ®Google Scholar
• Traweger A, Fuchs R, Krizbai I A, Weiger T M, Bauer H C, Bauer H. The tight junction protein ZO-2 localizes to the nucleus and interacts with the heterogeneous nuclear ribonucleoprotein scaffold attachment factor-B. The Journal of Biological Chemistry 2003; 278: 2692–2700
   PubMedGoogle Scholar
• Tsukamoto T, Nigam S K. Role of tyrosine phosphorylation in the reassembly of occludin and other tight junction proteins. American Journal of Physiology 1999; 276: F737–F350
   PubMed Web of Science ®Google Scholar
• Tsukita S, Furuse M. The structure and function of claudins, cell adhesion molecules at tight junctions. Annals of the New York Academy of Sciences 2000; 915: 129–135
   PubMed Web of Science ®Google Scholar
• Tsukita S, Furuse M, Itoh M. Multifunctional strands in tight junction. Nature Reviews Molecular Cell Biology 2001; 2: 285–293
   PubMed Web of Science ®Google Scholar
• Tunggal J A, Helfrich I, Schmitz A, Schwarz H, Günzel D, Fromm M, Kemler R, Krieg T, Niessen C M. E-cadherin is essential for in vivo epidermal barrier function by regulating tight junction. European Molecular Biology Organization Journal 2005; 24: 1146–1156
   PubMed Web of Science ®Google Scholar
• Wacheck V, Selzer E, Gunsberg P, Lucas T, Meyer H, Thallinger C, Monia B P, Jansen B. Bcl-x(L) antisense oligonucleotides radiosensitise colon cancer cells. British Journal of Cancer 2003; 89: 1352–1357
   PubMedGoogle Scholar
• Yap A S, Brieher W M, Gumbiner B M. Molecular and functional analysis of cadherin-based adherens junctions. Annual Review of Cell and Developmental Biology 1997; 13: 119–146
   PubMed Web of Science ®Google Scholar