Low doses of ionizing radiation can prevent radiation-induced colonic epithelial hyporesponsiveness to muscarinic agonists

References

• Alburquerque F C, Smith E H, Kellum J D. 5-HT induces cAMP production in crypt colonocytes at a 5-HT4 receptor. Journal of Surgical Research 1998; 77: 137–140
   PubMedGoogle Scholar
• Asfaha S, Bell C J, Wallace J L, MacNaughton W K. Prolonged colonic epithelial hyporesponsiveness after colitis: Role of inducible nitric oxide synthase. American Journal of Physiology 1999; 276(3, Pt 1)G703–G710
   Web of Science ®Google Scholar
• Asfaha S, MacNaughton W K, Appleyard C B, Chadee K, Wallace J L. Persistent epithelial dysfunction and bacterial translocation after resolution of intestinal inflammation. American Journal of Physiology. Gastrointestinal and Liver Physiology 2001; 281(3)G635–G644
   Web of Science ®Google Scholar
• Busch D B. Pathology of the radiation-damaged bowel. Radiation Enteritis, R B Galland, J Spencer. Edward Arnold, London 1990; 66–87
   Google Scholar
• Connor J R, Manning P T, Settle S L, Moore W M, Jerome G M, Webber R K, Tjoeng F S, Currie M G. Suppression of adjuvant-induced arthritis by selective inhibition of inducible nitric oxide synthase. European Journal of Pharmacology 1995; 273(1 – 2)15–24
   PubMedGoogle Scholar
• Cooper D M, Mons N, Karpen J W. Adenylyl cyclases and the interaction between calcium and cAMP signalling. Nature 1995; 374: 421–424
   PubMed Web of Science ®Google Scholar
• Domaratskaia E I, Starostin V I, Tsetlin V V, Butorina N N, Bueverova E I, Bragina E V, Khrushchov N G. [Effect of continuous gamma-radiation at low doses on clonogenic hemopoietic (CFU-S) and stromal (CFU-F) bone marrow cells]. Izvestiia Akademii nauk. Seriia biologicheskaia 2002; 4: 402–406
   Google Scholar
• Dublineau I, Morel E, Griffiths N M. Characterization of altered absorptive and secretory functions in the rat colon after abdominal irradiation: Comparison with the effects of total-body irradiation. Radiation Research 2002; 157(1)52–61
   PubMedGoogle Scholar
• Francois A, Aigueperse J, Gourmelon P, MacNaughton W K, Griffiths N M. Exposure to ionizing radiation modifies neurally-evoked electrolyte transport and some inflammatory responses in rat colon in vitro. International Journal of Radiation Biology 1998; 73(1)93–101
   PubMed Web of Science ®Google Scholar
• Francois A, Ksas B, Gourmelon P, Griffiths N M. Changes in 5-HT-mediated pathways in radiation-induced attenuation and recovery of ion transport in rat colon. American Journal of Physiology, Gastrointestinal and Liver Physiology 2000a; 278(1)G75–G82
   Google Scholar
• Francois A, Ksas B, Gourmelon P, Griffiths N M. Changes in 5-HT-mediated pathways in radiation-induced attenuation and recovery of ion transport in rat colon. American Journal of Physiology, Gastrointestinal and Liver Physiology 2000b; 278(1)G75–G82
   Google Scholar
• Freeman S L, MacNaughton W K. Ionizing radiation induces iNOS-mediated epithelial dysfunction in the absence of an inflammatory response. American Journal of Physiology, Gastrointestinal and Liver Physiology 2000; 278(2)G243–G250
   Web of Science ®Google Scholar
• Freeman S L, MacNaughton W K. Nitric oxide inhibitable isoforms of adenylate cyclase mediate epithelial secretory dysfunction following exposure to ionising radiation. Gut 2004; 53(2)214–221
   PubMedGoogle Scholar
• Hill J, Howlett A, Klein C. Nitric oxide selectively inhibits adenylyl cyclase isoforms 5 and 6. Cellular Signalling 2000; 12: 233–237
   PubMedGoogle Scholar
• Hosoi Y, Miyachi H, Matsumoto Y, Enomoto A, Nakagawa K, Suzuki N, Ono T. Induction of interleukin-1beta and interleukin-6 mRNA by low doses of ionizing radiation in macrophages. International Journal of Cancer 2001; 96(5)270–276
   PubMed Web of Science ®Google Scholar
• Iyer R, Lehnert B E. Low dose, low-LET ionizing radiation-induced radioadaptation and associated early responses in unirradiated cells. Mutation Research 2002; 503(1 – 2)1–9
   PubMedGoogle Scholar
• Kojima S, Matsuki O, Kinoshita I, Gonzalez T V, Shimura N, Kubodera A. Does small-dose gamma-ray radiation induce endogenous antioxidant potential in vivo. Biological & Pharmaceutical Bulletin 1997; 20(6)601–604
   PubMedGoogle Scholar
• Kojima S, Matsuki O, Nomura T, Yamaoka K, Takahashi M, Niki E. Elevation of antioxidant potency in the brain of mice by low-dose gamma-ray irradiation and its effect on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced brain damage. Free Radical Biology & Medicine 1999; 26(3 – 4)388–395
   PubMedGoogle Scholar
• Lebrun F, Francois A, Vergnet M, Lebaron-Jacobs L, Gourmelon P, Griffiths N M. Ionizing radiation stimulates muscarinic regulation of rat intestinal mucosal function. The American Journal of Physiology 1998; 275(6, Pt 1)G1333–G1340
   Google Scholar
• Liu X D, Ma S M, Liu S Z. Effects of 0.075 Gy x-ray irradiation on the expression of IL-10 and IL-12 in mice. Physics in Medicine and Biology 2003; 48(13)2041–2049
   PubMedGoogle Scholar
• MacNaughton W K, Aurora A R, Bhamra J, Sharkey K A, Miller M J. Expression, activity and cellular localization of inducible nitric oxide synthase in rat ileum and colon post-irradiation. International Journal of Radiation Biology 1998; 74(2)255–264
   PubMed Web of Science ®Google Scholar
• MacNaughton W K, Leach K E, Prud'homme-Lalonde L, Harding R K. Exposure to ionizing radiation increases responsiveness to neural secretory stimuli in the ferret jejunum in vitro. International Journal of Radiation Biology 1997; 72(2)219–226
   PubMedGoogle Scholar
• MacNaughton W K, Leach K E, Prud'homme-Lalonde L, Ho W, Sharkey K A. Ionizing radiation reduces neurally evoked electrolyte transport in rat ileum through a mast cell-dependent mechanism. Gastroenterology 1994; 106(2)324–335
   PubMedGoogle Scholar
• MacNaughton W K, Lowe S S, Cushing K. Role of nitric oxide in inflammation-induced suppression of secretion in a mouse model of acute colitis. The American Journal of Physiology 1998; 275(6, Pt 1)G1353–G1360
   Google Scholar
• McCabe R D, Dharmsathaphorn K. Mechanism of VIP-stimulated chloride secretion by intestinal epithelial cells. Annals of the New York Academy of Sciences 1988; 527: 326–345
   PubMed Web of Science ®Google Scholar
• McRoberts J A, Beuerlein G, Dharmsathaphorn K. Cyclic AMP and Ca2+-activated K+ transport in a human colonic epithelial cell line. The Journal of Biological Chemistry 1985; 260(26)14163–14172
   PubMedGoogle Scholar
• Miller G M, Kajioka E H, Andres M L, Gridley D S. Dose and timing of total-body irradiation mediate tumor progression and immunomodulation. Oncology Research 2002; 13(1)9–18
   PubMedGoogle Scholar
• Mitchel R E, Dolling J A, Misonoh J, Boreham D R. Influence of prior exposure to low-dose adapting radiation on radiation-induced teratogenic effects in fetal mice with varying Trp53 function. Radiation Research 2002; 158(4)458–463
   PubMedGoogle Scholar
• Miyachi Y, Koike T, Murol K, Kanao T, Kawamoto T, Yamada T. Marked depression of radiation-induced emesis in frogs following prior exposure to a brief dose of X-rays. Canadian Journal of Physiology and Pharmacology 2002; 80(8)828–832
   PubMedGoogle Scholar
• Morel E, Dublineau I, Griffiths N M. Effect of radiation on cAMP, cGMP and Ca(2+)(i) pathways and their interactions in rat distal colon. Radiation Research 2003; 160(3)263–272
   PubMedGoogle Scholar
• Morel E, Dublineau I, Lebrun F, Griffiths N M. Alterations of the VIP-stimulated cAMP pathway in rat distal colon after abdominal irradiation. American Journal of Physiology. Gastrointestinal and Liver Physiology 2002; 282(5)G835–G843
   Google Scholar
• Nose M, Wang B, Itsukaichi H, Yukawa O, Hayata I, Yamada T, Ohyama H. Rescue of lethally irradiated mice from hematopoietic death by pre-exposure to 0.5 Gy X rays without recovery from peripheral blood cell depletion and its modification by OK432. Radiation Research 2001; 156(2)195–204
   PubMedGoogle Scholar
• Potten C S, Merritt A, Hickman J, Hall P, Faranda A. Characterization of radiation-induced apoptosis in the small intestine and its biological implications. International Journal of Radiation Biology 1994; 65(1)71–78
   PubMed Web of Science ®Google Scholar
• Redpath J L, Lu Q, Lao X, Molloi S, Elmore E. Low doses of diagnostic energy X-rays protect against neoplastic transformation in vitro. International Journal of Radiation Biology 2003; 79: 235–240
   PubMed Web of Science ®Google Scholar
• Wang B, Ohyama H, Nose T, Itsukaichi H, Nakajima T, Yukawa O, Odaka T, Tanaka K, Kojima E, Yamada T, Hayata I. Adaptive response in embryogenesis: I. Dose and timing of radiation for reduction of prenatal death and congenital malformation during the late period of organogenesis. Radiation Research 1998; 150(1)120–122
   PubMedGoogle Scholar
• Wang G J, Cai L. Induction of cell-proliferation hormesis and cell-survival adaptive response in mouse hematopoietic cells by whole-body low-dose radiation. Toxicological Sciences 2000; 53: 369–376
   PubMed Web of Science ®Google Scholar
• Wolff S. Aspects of the adaptive response to very low doses of radiation and other agents. Mutation Research 1996; 358(2)135–142
   PubMedGoogle Scholar
• Young R W. Acute radiation syndrome. Military Radiology, J J Conklin, R I Walker. Academic Press Inc., San Diego 1987; 165–190
   Google Scholar