119
Views
22
CrossRef citations to date
0
Altmetric
Thorium Effects on Neurobehaviour in Mice

Thorium-induced neurobehavioural and neurochemical alterations in Swiss mice

, , , , &
Pages 338-347 | Received 18 Jan 2008, Accepted 04 Dec 2008, Published online: 03 Jul 2009

References

  • Abdel-Rehman A, Shetty A K, Abou-Donia M B. Disruption of the blood-brain barrier and neuronal cell death in cingulated cortex, dentate gyrus, thalamus, and hypothalamus in a rat model of Gulf-War syndrome. Neurobiolgy Diseases 2002; 10: 306–326
  • Abou-Donia M B, Dechkovskaia A M, Goldstein L B, Shah D U, Bullman S L, Khan W A. Uranyl acetate induced sensorimotor deficit and increased nitric oxide generation in the central nervous system in rats. Pharmacology Biochemistry Behavior 2002; 72: 881–890
  • Aebi H. Catalase in vitro. Methods in Enzymology 1984; 105: 121–126
  • Antonio M T, Corredor L, Leret M L. Study of the activity of several brain enzymes like markers of the neurotoxicity induced by perinatal exposure to lead and/or cadmium. Toxicology Letter 2003; 143: 331–340
  • Agency for Toxic Substances and Disease Registry (ATSDR). Toxicological profile for thorium. Toxicological profile, Department of Health and Human Services. 1990; 32, Agency for toxic substances and disease registry, Atlanta GA, USA
  • Barber D S, Hancock S K, McNally A M, Hinckley J, Binder E, Zimmerman K, Ehrich M F, Jortner B S. Neurological effects of uranium exposure with and without stress. Neurotoxicology 2007; 28: 110–1119
  • Briner W, Murray J. Effect of short term and long term depleted uranium exposure on open field behavior and brain lipid oxidation in rats. Neurotoxicology and Teratology 2005; 27: 135–144
  • Brush A. Metals and neuroscience. Current Opinion in Chemical Biology 2000; 4: 184–191
  • Bussy C, Lestaevel P, Dhieux B, Amourette C, Paquet F, Gourmelon P, Houpert P. Chronic ingestion of uranyl nitrate perturbs acetylcholinesterase activity and monoamine metabolism in male rat brain. Neurotoxicology 2006; 27: 245–252
  • Campos M P, Pecequilo B RS. Thoron exposure for workers with naturally occurring radioactive materials. International Journal of Low Radiation 2007; 4: 53–60
  • Carbonell T, Rama R. Iron, oxidative stress and early neurological deterioration in ischemic stroke. Current Medicinal Chemistry 2007; 14: 857–874
  • Domingo J L, Llobet J M, Toma J M, Corbella J. Acute toxicity of uranium in rats and mice. Bulletin of Environmental Contamination and Toxicology 1987; 39: 168–174
  • Fridovich I. Superoxide dismutases. Annual Review of Biochemistry 1975; 44: 147–159
  • Ghosh S, Kumar A, Pandey B N, Mishra K P. Acute exposure of uranyl nitrate causes lipid peroxidation and histopathological damage in brain and bone of Wistar rat. Journal of Environmental Pathology Toxicology and Oncology 2007; 26: 255–261
  • Glover S E, Traub R J, Grimm C A, Filby R H. Distribution of natural thorium in the tissues of a whole body. Radiation Protection Dosimetry 2001; 97: 153–160
  • Gulya K, Rakonczay Z, Kasa P. Cholinotoxic effects of aluminum in rat brain. Journal of Neurochemistry 1990; 54: 1020–1026
  • Halliwell B, Gutteridge J MC. Free radicals in biology and medicine. Clarendon Press, Oxford, UK 1989
  • Hayes W J, Laws E R. Handbook of pesticide toxicology. Academic Press Inc, New York 1991
  • Hee S S, Boyle J R. Simultaneous multielemental analysis of some environmental and biological samples by inductively coupled plasma atomic emission spectrometry. Annals of Chemistry 1988; 60: 1033–1042
  • Holmes L. Determination of thorium by ICP-MS and ICP-OES. Radiation Protection Dosimetry 2001; 97: 117–122
  • Houpert P, Bizot J C, Bussy C, Dhieux B, Lestaevel P, Gourmelon, Paquet F. Comaparison of the effects of enriched uranium and 137-cesium on the behaviour of rats after chronic exposure. International Journal of Radiation Biology 2007; 83: 99–104
  • Jarrard L E. On the role of the hippocampus in learning and memory in the rat. Behavioral Neural Biology 1993; 60: 9–26
  • Juliao L M, Sousa W O, Santos M S, Fernandes P C. Determination of 238U, 234U, 232Th, 228Th, 228Ra, 226Ra and 210Pb concentration in excreta samples of inhabitants of a high natural background area. Radiation Protection Dosimetry 2003; 105: 379–382
  • Kaizer R R, Correa M C, Spanevello R M, Morsch V M, Mazzanti C M, Goncalves J F, Schetinger M R. Acetylcholinesterase activation and enhanced lipid peroxidation after long-term exposure to low levels of aluminum on different mouse brain regions. Journal of Inorganic Biochemistry 2005; 99: 1865–1870
  • Kumar A, Mishra P, Ghosh S, Sharma P, Ali M, Pandey B N, Mishra K P. Thorium induced oxidative stress mediated toxicity in mice and its abrogation by diethylenetriamine pentaacetate. International Journal of Radiation Biology 2008; 84: 337–349
  • Lestaevel P, Houpert P, Bussy C, Dhieux B, Gourmelon P, Paquet F. The brain is a target organ after acute exposure to depleted uranium. Toxicology 2005; 212: 219–226
  • Lowry O H, Rosebrough N J, Farr A L, Randall R J. Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry 1951; 193: 265–275
  • Mandavilli B S, Rao K S. Neurons in the cerebral cortex are more susceptible to DNA damage in ageing rat brain. Biochemistry Molecular Biology International 1996; 40: 507–514
  • Meng Z, Qin G, Zhang B, Geng H, Bai Q, Bai W, Liu C. Oxidative damage of sulfur dioxide inhalation on lungs and hearts of mice. Environmental Research 2003; 93: 285–292
  • Miller D B, O'Callagham. Effect of aging and stress on hippocampal structure and function. Metabolism 2003; 52: 17–21
  • Moreira E G, Vassilieff I, Vassilieff V S. Developmental lead exposure: Behavioral alterations in the short and long term. Neurotoxicology and Teratology 2001; 23: 489–495
  • Peakall D. Animal biomarkers as pollution indicators. Chapman and Hall, London 1992
  • Raina V K, Srivenkatesan, Khatri D C, Lahiri D K. Critical facility for lattice physics experiments for the advanced heavy water reactor and the 500 MWe pressurized heavy water reactors. Nuclear Engineering and Design 2006; 236: 758–769
  • Reddy G R, Devi B C, Chetty C S. Developmental lead neurotoxicity: Alterations in brain cholinergic system. Neurotoxicology 2007; 28: 402–407
  • Schallreuter K U, Elwary S M, Gibbons N C, Rokos H, Wood J M. Activation/deactivation of acetylcholinesterase by H2O2: More evidence for oxidative stress in vitiligo. Biochemical and Biophysical Research Communication 2004; 315: 502–508
  • Sharma P, Ahmad Shah Z, Kumar A, Islam F, Mishra K P. Role of combined administration of Tiron and glutathione against aluminum-induced oxidative stress in rat brain. Journal of Trace Elements in Medicine and Biology 2007; 21: 63–70
  • Sharma P, Mishra K P. Aluminum-induced maternal and developmental toxicity and oxidative stress in rat brain: Response to combined administration of Tiron and glutathione. Reproductive Toxicology 2006; 21: 313–321
  • Sinha C, Seth K, Islam F, Chaturvedi R K, Shukla S, Mathur N, Srivastava N, Agrawal A K. Behavioral and neurochemical effects induced by pyrethroid-based mosquito repellent exposure in rat offsprings during prenatal and early postnatal period. Neurotoxicology Teratology 2006; 28: 472–481
  • Squire L R. Memory and the hippocampus: A synthesis from findings with rats. Physiological Review 1992; 99: 195–231
  • Stoltenburg-Didinger G. Neuropathology of the hippocampus and its susceptibility to neurotoxic insult. Neurotoxicology 1994; 15: 445–450
  • Tukalenko E V, Varetsky V V, Rakochi O G, Dmitrieva I R, Makarchuk M U. Effects of non-lethal doses of ionising radiation on the instrumental behaviour of rats. International Journal of Low Radiation 2007; 4: 232–247
  • Walsh T J, Emerich D F. The hippocampus as a common target of neurotoxic agents. Toxicology 1988; 49: 137–140
  • Zheng W, Aschner M, Ghersi-Egea J F. Brain barrier systems: A new frontier in metal neurotoxicological research. Toxicology and Applied Pharmacology 2003; 192: 1–11

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.