Advanced search
Publication Cover
International Journal of Radiation Biology Volume 93, 2017 - Issue 4
Submit an article Journal homepage
114
Views
10
CrossRef citations to date
0
Altmetric
Original Articles

Inducing mutations through γ-irradiation in seeds of Mucuna pruriens for developing high L-DOPA-yielding genotypes

Susheel Kumar SinghCouncil of Scientific and Industrial Research (CSIR), Central Institute of Medicinal and Aromatic Plants (CIMAP), Lucknow, India
,
Deepti YadavCouncil of Scientific and Industrial Research (CSIR), Central Institute of Medicinal and Aromatic Plants (CIMAP), Lucknow, India
,
Raj Kishori LalCouncil of Scientific and Industrial Research (CSIR), Central Institute of Medicinal and Aromatic Plants (CIMAP), Lucknow, India
,
Madan M. GuptaCouncil of Scientific and Industrial Research (CSIR), Central Institute of Medicinal and Aromatic Plants (CIMAP), Lucknow, India
&
Sunita Singh DhawanCouncil of Scientific and Industrial Research (CSIR), Central Institute of Medicinal and Aromatic Plants (CIMAP), Lucknow, IndiaCorrespondence[email protected]
Pages 426-432 | Received 28 Oct 2015, Accepted 10 Oct 2016, Published online: 29 Nov 2016

References

  • Arim OJ, Waceke JW, Waudo SW, Kimenju JW. 2011. Managing nematode pests and improving yield of pineapple with Mucuna pruriens in Ghana. J Entomol Nematol. 3:20–24.
  • Atienzar FA, Jha AN. 2004. The random amplified polymorphic DNA (RAPD) assay to determine DNA alterations, repair and transgenerational effects in B[a]P exposed Daphnia magna. Mutat Res. 552:125–140.
  • Atienzar FA, Jha AN. 2006. The random amplified polymorphic DNA (RAPD) assay and related techniques applied to genotoxicity and carcinogenesis studies: a critical review. Mutat Res. 613:76–102.
  • Atienzar FA, Venier P, Jha AN, Depledge MH. 2002. Evaluation of the random amplified polymorphic DNA (RAPD) assay for the detection of DNA damage and mutations. Mutat Res. 521:151–163.
  • Carsky RJ, Tarawali SA, Becker M, Chikoye D, Tian G, Sanginga N. 1998. Mucuna–herbaceous cover legume with potential for multiple uses. Proc Res Crop Manag Res Mono. No. 25. Ibadan, Nigeria: IITA.
  • Danylchenoko O, Sorochinsky B. 2005. Use of RAPD assay for the detection of mutation changes in plant DNA induced by UB-B and γ-rays. BMC Plant Biol. 5:SI–S9. doi:10.1186/1471-2229-5-S1-S9.
  • Dhawan SS, Rai GK, Darokar MP, Lal RK, Misra HO, Khanuja SP. 2011. Comparative genetic analysis of trichome-less and normal pod genotypes of Mucuna pruriens (Fabaceae). Genet Mol Res. 15:2049–2056.
  • Dhawan SS, Shukla P, Gupta P, Lal RK. 2015. A cold-tolerant evergreen interspecific hybrid of Ocimum kilimandscharicum and Ocimum basilicum: analyzing trichomes and molecular variation. Protoplasma. 253:845–855.
  • Dhillon RS, Saharan RP, Jattan M, Rani T, Sheokand RN, Dalal V, Wuehlisch GV. 2014. Molecular characterization of induced mutagenesis through γ-radiation using RAPD markers in Jatropha curcas L. Afr J Biotechnol. 12:806–813.
  • Eze ED, Mohammed A, Musa KY, Tanko Y. 2012. Evaluation of effect of ethanolic leaf extract of Mucuna pruriens on blood glucose levels in alloxan-induced diabetic Wistar rats. Asian J Med Sci. 4:23–28.
  • Fujii Y, Shibuyat T, Yasuda T. 1991. L-3,4-Dihydroxyphenylalanine as an allelochemical candidate from Mucuna pruriens (L.) DC. var. utilis. Agric Bioi Chem. 55:617–618.
  • Girija M, Gnanamurthy S, Dhanavel D. 2013. Genetic diversity analysis of cowpea variant (Vigna unguiculata (L.) Walp as revealed by RAPD marker. Inter J Ad Res. 4:139–147.
  • Khanuja SPS, Shasany AK, Darokar MP, Kumar S. 1999. Rapid isolation of DNA from dry and fresh samples of plants producing large amounts of secondary metabolites and essential oils. Plant Mol Biol Rep. 17:1–7.
  • Lal RK, 2015. Genotype selection for agronomical trait–seed yield in kewachh {Mucuna pruriens} (L.). BMC Plant Biol. 6:62–70.
  • Lieu CA, Venkiteswaran K, Gilmour TP, Rao AN, Petticoffer AC, Gilbert EV, Deogaonkar M, Manyam BV, Subramanian T. 2012. The Antiparkinsonian and Antidyskinetic mechanisms of Mucuna pruriens in the MPTP-treated nonhuman primate. Evid Based Complement Alternat Med. 2012:1–10. doi:10.1155/2012/840247.
  • Manyam BV, Sanchez RJR. 1999. Traditional and complementary therapies in Parkinson’s disease. Adv Neurol. 80:565–574.
  • Nei M, Li WH. 1979. Mathematical model for studying genetic variation in terms of restriction endonucleases. Proc Natl Acad Sci USA. 76:5269–5273.
  • Pulikkalpura H, Rajani K, Mathew PJ, Baby S. 2015. Levodopa in Mucuna pruriens and its degradation. Sci Rep. 5:11078.
  • Raina AP, Khatri R. 2013. Quantitative determination of L-DOPA in seeds of Mucuna pruriens germplasm by high performance thin layer chromatography. BMC Plant Biol. 73:459–462.
  • Rohlf FJ. 2000. NTSYS-pc, numerical taxonomy and multivariate analysis system, Version 2.10e. New York: Applied Biostatistics, Inc.
  • Scirè A, Tanfani F, Bertoli E, Furlani E, Nadozie HO, Cerutti H, Cortelazzo A, Bini L, Guerranti R. 2011. The belonging of gpMuc, a glycoprotein from Mucuna pruriens seeds, to the Kunitz-type trypsin inhibitor family explains its direct anti-snake venom activity. Phytomedicine. 18:887–895.
  • Shimada A, Shima A. 1998. Combination of genomic DNA fingerprinting into the medaka specific-locus test system for studying environmental germ-line mutagenesis. Mutat Res. 399:149–165.
  • Siddhuraju P, Becker K. 2001. Rapid reversed-phase high performance liquid chromatographic method for the quantification of L-Dopa (L-3,4-dihydroxyphenylalanine), non-methylated and methylated tetrahydroisoquinoline compounds from Mucuna beans. Food Chem. 72:389–394.
  • Singh AP, Sarkar S, Tripathi M, Rajender S. 2013. Mucuna pruriens and its major constituent L-DOPA recover spermatogenic loss by combating ROS, loss of mitochondrial membrane potential and apoptosis. PLoS One. 8:e54655. doi: http://dx.doi:10.1371/journal.pone.0054655.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.