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Original Articles

Imaging, biodistribution and efficacy evaluation of 188Re-human serum albumin microspheres via intraarterial route in an orthotopic hepatoma model

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Pages 477-486 | Received 11 Aug 2016, Accepted 17 Dec 2016, Published online: 20 Feb 2017

References

  • Bernal P, Raoul JL, Vidmar G, Sereegotov E, Sundram FX, Kumar A, Jeong JM, Pusuwan P, Divgi C, Zanzonico P, et al. 2007. Intra-arterial rhenium-188 lipiodol in the treatment of inoperable hepatocellular carcinoma: results of an IAEA-sponsored multination study. Int J Radiat Oncol Biol Phys. 69:1448–1455.
  • Bruix J, Llovet JM. 2009. Major achievements in hepatocellular carcinoma. Lancet. 373:614–616.
  • Buendia MA, Neuveut C. 2015. Hepatocellular carcinoma. Cold Spring Harb Perspect Med. 5:a021444.
  • Chang YJ, Chang CH, Yu CY, Chang TJ, Chen LC, Chen MH, Lee TW, Ting G. 2010. Therapeutic efficacy and microSPECT/CT imaging of 188Re-DXR-liposome in a C26 murine colon carcinoma solid tumor model. Nucl Med Biol. 37:95–104.
  • Chen CJ, Yang HI, Su J, Jen CL, You SL, Lu SN, Huang GT, Iloeje UH, Group R-HS. 2006. Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level. JAMA. 295:65–73.
  • Chen LC, Wu YH, Liu IH, Ho CL, Lee WC, Chang CH, Lan KL, Ting G, Lee TW, Shien JH. 2012. Pharmacokinetics, dosimetry and comparative efficacy of 188Re-liposome and 5-FU in a CT26-luc lung-metastatic mice model. Nucl Med Biol. 39:35–43.
  • Colombo M, Sangiovanni A. 2015. Treatment of hepatocellular carcinoma: beyond international guidelines. Liver Int. 35(Suppl 1):129–138.
  • Cremonesi M, Ferrari M, Bartolomei M, Orsi F, Bonomo G, Arico D, Mallia A, De Cicco C, Pedroli G, Paganelli G. 2008. Radioembolisation with 90Y-microspheres: dosimetric and radiobiological investigation for multi-cycle treatment. Eur J Nucl Med Mol Imaging. 35:2088–2096.
  • Culler MD, Oberg K, Arnold R, Krenning EP, Sevilla I, Diaz JA. 2011. Somatostatin analogs for the treatment of neuroendocrine tumors. Cancer Metastasis Rev. 30(Suppl 1):9–17.
  • de Kemp RA, Epstein FH, Catana C, Tsui BM, Ritman EL. 2010. Small-animal molecular imaging methods. J Nucl Med. 51(Suppl.1):18S–32S.
  • Druce MR, Lewington V, Grossman AB. 2010. Targeted radionuclide therapy for neuroendocrine tumours: principles and application. Neuroendocrinology. 91:1–15.
  • Elschot M, Nijsen JF, Lam MG, Smits ML, Prince JF, Viergever MA, van den Bosch MA, Zonnenberg BA, de Jong HW. 2014. (99m)Tc-MAA overestimates the absorbed dose to the lungs in radioembolization: a quantitative evaluation in patients treated with (166)Ho-microspheres. Eur J Nucl Med Mol Imaging. 41:1965–1975.
  • Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, Parkin DM, Forman D, Bray F. 2014. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 136:E359–E386.
  • Garin E, Denizot B, Roux J, Noiret N, Lepareur N, Moreau M, Mesba H, Laurent JF, Herry JY, Bourguet P, et al. 2005. Description and technical pitfalls of a hepatoma model and of intra-arterial injection of radiolabelled lipiodol in the rat. Lab Anim. 39:314–320.
  • Gil-Alzugaray B, Chopitea A, Inarrairaegui M, Bilbao JI, Rodriguez-Fraile M, Rodriguez J, Benito A, Dominguez I, D’Avola D, Herrero JI, et al. 2013. Prognostic factors and prevention of radioembolization-induced liver disease. Hepatology. 57:1078–1087.
  • Graham KC, Wirtzfeld LA, MacKenzie LT, Postenka CO, Groom AC, MacDonald IC, Fenster A, Lacefield JC, Chambers AF. 2005. Three-dimensional high-frequency ultrasound imaging for longitudinal evaluation of liver metastases in preclinical models. Cancer Res. 65:5231–5237.
  • Lambert B, Bacher K, Defreyne L, Gemmel F, Van Vlierberghe H, Jeong JM, Dierckx RA, Van de Wiele C, Thierens H, De Vos F. 2005. 188Re-HDD/lipiodol therapy for hepatocellular carcinoma: a phase I clinical trial. J Nucl Med. 46:60–66.
  • Lambert B, Van de Wiele C. 2005. Treatment of hepatocellular carcinoma by means of radiopharmaceuticals. Eur J Nucl Med Mol Imaging. 32:980–989.
  • Leung WT, Lau WY, Ho SK, Chan M, Leung NW, Lin J, Metreweli C, Johnson PJ, Li AK. 1994. Measuring lung shunting in hepatocellular carcinoma with intrahepatic-arterial technetium-99m macroaggregated albumin. J Nucl Med. 35:70–73.
  • Liepe K, Brogsitter C, Leonhard J, Wunderlich G, Hliscs R, Pinkert J, Folprecht G, Kotzerke J. 2007. Feasibility of high activity rhenium-188-microsphere in hepatic radioembolization. Jpn J Clin Oncol. 37:942–950.
  • Liepe K, Kotzerke J, Lambert B. 2005. Advantage of 188Re-radiopharmaceuticals in hepatocellular cancer and liver metastases. J Nucl Med. 46:1407–1408.
  • Lin SB, Wu LC, Huang SL, Hsu HL, Hsieh SH, Chi CW, Au LC. 2000. In vitro and in vivo suppression of growth of rat liver epithelial tumor cells by antisense oligonucleotide against protein kinase C-alpha. J Hepatol. 33:601–608.
  • Murthy R, Kamat P, Nunez R, Salem R. 2008. Radioembolization of yttrium-90 microspheres for hepatic malignancy. Semin Intervent Radiol. 25:48–57.
  • Neves M, Kling A, Oliveira A. 2005. Radionuclides used for therapy and suggestion for new candidates. J Radioanal Nucl Chem. 266:377–384.
  • Ni HC, Yu CY, Chen SJ, Chen LC, Lin CH, Lee WC, Chuang CH, Ho CL, Chang CH, Lee TW. 2015. Preparation and imaging of rhenium-188 labeled human serum albumin microsphere in orthotopic hepatoma rats. Appl Radiat Isot. 99:117–121.
  • Nowicki ML, Cwikla JB, Sankowski AJ, Shcherbinin S, Grimmes J, Celler A, Buscombe JR, Bator A, Pech M, Mikolajczak R, et al. 2014. Initial study of radiological and clinical efficacy radioembolization using 188Re-human serum albumin (HSA) microspheres in patients with progressive, unresectable primary or secondary liver cancers. Med Sci Monit. 20:1353–1362.
  • Okuda K. 2000. Hepatocellular carcinoma. J Hepatol. 32:225–237.
  • Peker A, Cicek O, Soydal C, Kucuk NO, Bilgic S. 2015. Radioembolization with yttrium-90 resin microspheres for neuroendocrine tumor liver metastases. Diagn Interv Radiol. 21:54–59.
  • Pillai MR, Dash A, Knapp FF Jr. 2012. Rhenium-188: availability from the (188)W/(188)Re generator and status of current applications. Curr Radiopharm. 5:228–243.
  • Price TJ, Townsend A. 2008. Yttrium 90 microsphere selective internal radiation treatment of hepatic colorectal metastases. Arch Surg. 143:313–314.
  • Salem R, Lewandowski RJ. 2013. Chemoembolization and radioembolization for hepatocellular carcinoma. Clin Gastroenterol Hepatol. 11:604–611.
  • Ting G, Chang CH, Wang HE, Lee TW. 2010. Nanotargeted radionuclides for cancer nuclear imaging and internal radiotherapy. J Biomed Biotechnol. 2010:953537.
  • Wirtzfeld LA, Wu G, Bygrave M, Yamasaki Y, Sakai H, Moussa M, Izawa JI, Downey DB, Greenberg NM, Fenster A, et al. 2005. A new three-dimensional ultrasound microimaging technology for preclinical studies using a transgenic prostate cancer mouse model. Cancer Res. 65:6337–6345.
  • Wunderlich G, Drews A, Kotzerke J. 2005a. A kit for labeling of [188Re] human serum albumin microspheres for therapeutic use in nuclear medicine. Appl Radiat Isot. 62:915–918.
  • Wunderlich G, Pinkert J, Stintz M, Kotzerke J. 2005b. Labeling and biodistribution of different particle materials for radioembolization therapy with 188Re. Appl Radiat Isot. 62:745–750.
  • Wunderlich G, Schiller E, Bergmann R, Pietzsch HJ. 2010. Comparison of the stability of Y-90-, Lu-177- and Ga-68-labeled human serum albumin microspheres (DOTA-HSAM). Nucl Med Biol. 37:861–867.

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