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Original Article

Risk of solid cancer in low dose-rate radiation epidemiological studies and the dose-rate effectiveness factor

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Pages 1064-1078 | Received 03 Nov 2016, Accepted 07 Apr 2017, Published online: 15 May 2017

References

  • Akiba S, Mizuno S. 2012. The third analysis of cancer mortality among Japanese nuclear workers, 1991–2002: estimation of excess relative risk per radiation dose. J Radiol Prot. 32:73–83.
  • Akiba S. 2013. Cancer risk associated with low-dose and low-dose-rate ionizing radiation exposure. Genes Environ. 35:80–87.
  • Ashmore JP, Krewski D, Zielinski JM, Jiang H, Semenciw B. 1998. First analysis of mortality and occupational radiation exposure based on the national dose registry of Canada. Am J Epidemiol. 148:564–574.
  • Auvinen A, Pukkala E, Hyvonen H, Hakama M, Rytomaa T. 2002. Cancer incidence among Finnish nuclear reactor workers. J Occ Environ Med. 44:634–638.
  • Bauer S, Gusev BI, Pivina LM, Apsalikov KN, Grosche B. 2005. Radiation exposure due to local fallout from Soviet atmospheric nuclear weapons testing in Kazakhstan: solid cancer mortality in the Semipalatinsk historical cohort, 1960–1999. Radiat Res. 164:409–419.
  • Berrington A, Darby SC, Weiss HA, Doll R. 2001. 100 years of observation on British radiologists: mortality from cancer and other causes 1897–1997. Br J Radiol. 74:507–519.
  • Bevington PR, Robinson DK. 2003. Data reduction and error analysis for the physical sciences. Vol. 3rd ed. New York: McGraw-Hill.
  • Boice JD Jr, Cohen SS, Mumma MT, Ellis ED, Eckerman KF, Leggett RW, Boecker BB, Brill AB, Henderson BE. 2011. Updated mortality analysis of radiation workers at Rocketdyne (Atomics International), 1948–2008. Radiat Res. 176:244–258.
  • Cardis E, Gilbert E, Carpenter L, Howe G, Kato I, Armstrong B, Beral V, Cowper G, Douglas A, Fix J, et al. 1995. Effects of low doses and low dose rates of external ionizing radiation: cancer mortality among nuclear industry workers in three countries. Radiat Res. 142:117–132.
  • Cardis E, Vrijheid M, Blettner M, Gilbert E, Hakama M, Hill C, Howe G, Kaldor J, Muirhead CR, Schubauer-Berigan M, et al. 2007. The 15-country collaborative study of cancer risk among radiation workers in the nuclear industry: estimates of radiation-related cancer risks. Radiat Res. 167:396–416.
  • Cornell JE, Mulrow CD, Localio R, Stack CB, Meibohm AR, Guallar E, Goodman SN. 2014. Random-effects meta-analysis of inconsistent effects: a time for change. Ann Intern Med. 160:267–270.
  • DerSimonian R, Laird N. 1986. Meta-analysis in clinical trials. Control Clin Trials. 7:177–188.
  • DerSimonian R, Kacker R. 2007. Random-effects model for meta-analysis of clinical trials: an update. Contemp Clin Trials. 28:105–114.
  • DerSimonian R, Laird N. 2015. Meta-analysis in clinical trials revisited. Contemp Clin Trials. 45:139–145.
  • Duval S, Tweedie R. 2000. A nonparametric “trim and fill” method of accounting for publication bias in meta-analysis. J Am Stat Assoc. 98:89–98.
  • Egger M, Davey SG, Schneider M, Minder C. 1997. Bias in meta-analysis detected by a simple, graphical test. BMJ. 315:629–634.
  • Eidemüller M, Ostroumova E, Krestinina L, Epiphanova S, Akleyev A, Jacob P. 2010. Comparison of mortality and incidence solid cancer risk after radiation exposure in the Techa River Cohort. Radiat Environ Biophys. 49:477–490.
  • Engels H, Swaen GM, Slangen J, van Amersvoort L, Holmstock L, Van Mieghem E, Van Regenmortel I, Wambersie A. 2005. Radiation exposure and cause specific mortality among nuclear workers in Belgium (1969–1994). Rad Prot Dosim. 117:373–381.
  • Gilbert ES. 2009. The impact of dosimetry uncertainties on dose-response analyses. Health Phys. 97:487–492.
  • Gillies M, Haylock R. 2014. The cancer mortality and incidence experience of workers at British Nuclear Fuels plc, 1946–2005. J Radiol Prot. 34:595–623.
  • Gulis G. 2003. Cancer occurrence among radiation workers at Jaslovske Bohunice nuclear power plant. Central Eur J Public Health. 11:91–97.
  • Habib RR, Abdallah SM, Law M, Kaldor J. 2005. Mortality rates among nuclear industry workers at Lucas Heights Science and Technology Centre. Aust N Z J Public Health. 29:229–237.
  • Haley BM, Paunesku T, Grdina DJ, Woloschak GE. 2015. The increase in animal mortality risk following exposure to sparsely ionizing radiation is not linear quadratic with dose. PLoS One. 10:e0140989.
  • Hamra GB, Richardson DB, Cardis E, Daniels RD, Gillies M, O’Hagan J, Haylock R, Laurier D, Leuraud K, Moissonnier M, et al. 2016. Cohort profile: the International Nuclear Workers Study (INWORKS). Int J Epidemiol. 45:693–699.
  • Hoel DG. 2015. Comments on the DDREF estimate of the BEIR VII Committee. Health Phys. 108:351–356.
  • Howe GR, Zablotska LB, Fix JJ, Egel J, Buchanan J. 2004. Analysis of the mortality experience amongst U.S. nuclear power industry workers after chronic low-dose exposure to ionizing radiation. Radiat Res. 162:517–526.
  • Hsu W-L, Preston D, Soda M, Sugiyama H, Funamoto S, Kodama K, Kimura A, Kamada N, Dohy H, Tomonaga M, et al. 2013. The incidence of leukemia, lymphoma and multiple myeloma among atomic bomb survivors: 1950–2001. Radiat Res. 179:361–382.
  • Hunter N, Kuznetsova IS, Labutina EV, Harrison JD. 2013. Solid cancer incidence other than lung, liver and bone in Mayak workers: 1948–2004. Br J Cancer. 109:1989–1996.
  • Hwang S-L, Guo H-R, Hsieh W-A, Hwang J-S, Lee S-D, Tang J-L, Chen C-C, Chang T-C, Wang J-D, Chang WP. 2006. Cancer risks in a population with prolonged low dose-rate gamma-radiation exposure in radiocontaminated buildings, 1983–2002. Int J Radiat Biol. 82:849–858.
  • Hwang S-L, Hwang J-S, Yang Y-T, Hsieh WA, Chang T-C, Guo H-R, Tsai M-H, Tang J-L, Lin I-F, Chang WP. 2008. Estimates of relative risks for cancers in a population after prolonged low-dose-rate radiation exposure: a follow-up assessment from 1983 to 2005. Radiat Res. 170:143–148.
  • International Commission on Radiological Protection (ICRP). 2010. Conversion coefficients for radiological protection quantities for external radiation exposures. ICRP, Publication 116. Ann ICRP. 4:1–257.
  • Jacob P, Rühm W, Walsh L, Blettner M, Hammer G, Zeeb H. 2009. Is cancer risk of radiation workers larger than expected? Occup Environ Med. 66:789–796.
  • Jayalekshmi P, Gangadharan P, Vinu VS, Nair RRK, Nair MK, Rajan B, Akiba S. 2005. What did we learn from epidemiological studies in high background radiation areas in India. Int Congress Series. 1276:102–105.
  • Jeong M, Jin Y-W, Yang KH, Ahn Y-O, Cha C-Y. 2010. Radiation exposure and cancer incidence in a cohort of nuclear power industry workers in the Republic of Korea, 1992–2005. Radiat Environ Biophys. 49:47–55.
  • Jin Z-C, Zhou X-H, He J. 2015. Statistical methods for dealing with publication bias in meta-analysis. Stat Med. 34:343–360.
  • Kashcheev VV, Chekin SY, Maksioutov MA, Tumanov KA, Kochergina EV, Kashcheeva PV, Shchukina NV, Ivanov VK. 2015. Incidence and mortality of solid cancer among emergency workers of the Chernobyl accident: assessment of radiation risks for the follow-up period of 1992–2009. Radiat Environ Biophys. 54:13–23.
  • Kreuzer M, Dufey F, Laurier D, Nowak D, Marsh JW, Schnelzer M, Sogl M, Walsh L. 2015. Mortality from internal and external radiation exposure in a cohort of male German uranium millers, 1946–2008. Int Arch Occup Environ Health. 88:431–441.
  • Leuraud K, Richardson DB, Cardis E, Daniels RD, Gillies M, O’Hagan JA, Hamra GB, Haylock R, Laurier D, Moissonnier M, et al. 2015. Ionising radiation and risk of death from leukaemia and lymphoma in radiation-monitored workers (INWORKS): an international cohort study. Lancet Haematol. 2:e276–e281.
  • Liu JJ, Freedman DM, Little MP, Doody MM, Alexander BH, Kitahara CM, Lee T, Rajaraman P, Miller JS, Kampa DM, et al. 2014. Work history and mortality risks in 90,268 US radiological technologists. Occup Environ Med. 71:819–835.
  • Merzenich H, Hammer GP, Tröltzsch K, Ruecker K, Buncke J, Fehringer F, Blettner M. 2014. Mortality risk in a historical cohort of nuclear power plant workers in Germany: results from a second follow-up. Radiat Environ Biophys. 53:405–416.
  • Metz-Flamant C, Laurent O, Samson E, Caer-Lorho S, Acker A, Hubert D, Richardson DB, Laurier D. 2013. Mortality associated with chronic external radiation exposure in the French combined cohort of nuclear workers. Occup Environ Med. 70:630–638.
  • Moher D, Liberati A, Tetzlaff J, Altman DG. The PRISMA Group. 2009. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. J Clin Epidemiol. 62:1006–1012.
  • Muirhead CR, O’Hagan JA, Haylock RGE, Phillipson MA, Willcock T, Berridge GLC, Zhang W. 2009. Mortality and cancer incidence following occupational radiation exposure: third analysis of the National Registry for Radiation Workers. Br J Cancer. 100:206–212.
  • Nair RRK, Rajan B, Akiba S, Jayalekshmi P, Nair MK, Gangadharan P, Koga T, Morishima H, Nakamura S, Sugahara T. 2009. Background radiation and cancer incidence in Kerala, India-Karunagappally cohort study. Health Phys. 96:55–66.
  • NAS-NRC. 2006. Health risks from exposure to low levels of ionizing radiation: BEIR VII. Phase 2. Washington, DC: National Academies Press.
  • Ozasa K, Shimizu Y, Suyama A, Kasagi F, Soda M, Grant EJ, Sakata R, Sugiyama H, Kodama K. 2012. Studies of the mortality of atomic bomb survivors, Report 14, 1950–2003: an overview of cancer and noncancer diseases. Radiat Res. 177:229–243.
  • Piantadosi S, Byar D, Green S. 1988. The ecological fallacy. Am J Epidemiol. 127:893–904.
  • Preston DL, Lubin JH, Pierce DA. 1993. Epicure users guide. Seattle, WA: HiroSoft International Corporation.
  • Preston DL, Ron E, Tokuoka S, Funamoto S, Nishi N, Soda M, Mabuchi K, Kodama K. 2007. Solid cancer incidence in atomic bomb survivors: 1958–1998. Radiat Res. 168:1–64.
  • Richardson DB, Cardis E, Daniels RD, Gillies M, O’Hagan JA, Hamra GB, Haylock R, Laurier D, Leuraud K, Moissonnier M, et al. 2015. Risk of cancer from occupational exposure to ionising radiation: retrospective cohort study of workers in France, the United Kingdom, and the United States (INWORKS). BMJ 351:h5359.
  • Rühm W, Azizova TV, Bouffler SD, Little MP, Shore RE, Walsh L, Woloschak GE. 2015a. Dose rate effects in radiation biology and radiation protection. Ann ICRP. 45:262–279.
  • Rühm W, Woloschak GE, Shore RE, Azizova TV, Grosche B, Niwa O, Akiba S, Ono T, Suzuki K, Iwasaki T, et al. 2015b. Dose and dose rate effects of ionizing radiation: a discussion in the light of radiological protection. Radiat Environ Biophys. 54:379–401.
  • Schonfeld SJ, Krestinina LY, Epifanova S, Degteva MO, Akleyev AV, Preston DL. 2013. Solid cancer mortality in the Techa River cohort (1950–2007). Radiat Res. 179:183–189.
  • Schubauer-Berigan MK, Daniels RD, Bertke SJ, Tseng CY, Richardson DB. 2015. Cancer mortality through 2005 among a pooled cohort of U.S. nuclear workers exposed to external ionizing radiation. Radiat Res. 183:620–631.
  • Sokolnikov M, Preston D, Stram D. 2017. Mortality from solid cancers other than lung, liver and bone in relation to external dose among plutonium and non-plutonium workers in the Mayak Worker Cohort. Radiat Environ Biophys. 56:121–125.
  • Sokolnikov ME, Preston D, Gilbert E, Schonfeld S, Koshurnikova NA. 2015. Radiation effects on mortality from solid cancers other than lung, liver, and bone cancer in the Mayak worker cohort: 1948–2008. PLoS One. 10:e0117784.
  • Sont WN, Zielinski JM, Ashmore JP, Jiang H, Krewski D, Fair ME, Band PR, Letourneau EG. 2001. First analysis of cancer incidence and occupational radiation exposure based on the national dose registry of Canada. Am J Epidemiol. 153:309–318.
  • SSK 2014. Dose- and Dose-rate-effectiveness factor (DDREF), Recommendation by the German Commission on Radiological Protection with Scientific Grounds.
  • Sterne JAC, Egger M. 2001. Funnel plots for detecting bias in meta-analysis: guidelines on choice of axis. J Clin Epidemiol. 54:1046–1055.
  • Sterne JAC, Sutton AJ, Ioannidas JPA, Terrin N, Jones DR, Lau J, Carpenter J, Rücker G, Harbord RM, Schmid CH, et al. 2011. Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials. BMJ. 342:d4002. doi:10.1136/bmj.d4002
  • Stram DO, Preston DL, Sokolnikov M, Napier B, Kopecky KJ, Boice JD, Beck H, Till J, Bouville A. 2015. Shared dosimetry error in epidemiological dose-response analyses. PLoS One. 10:e0119418.
  • Sun Z, Inskip PD, Wang J, Kwon D, Zhao Y, Zhang L, Qin W, Fan S. 2016. Solid cancer incidence among Chinese medical diagnostic x-ray workers, 1950–1995: estimation of radiation-related risks. Int J Cancer. 138:2875–2883.
  • Sutton AJ, Higgins JPT. 2008. Recent developments in meta-analysis. Stat Med. 27:625–650.
  • Tao Z, Zha Y, Akiba S, Sun Q, Zou J, Li J, Liu Y, Kato H, Sugahara T, Wei L. 2000. Cancer mortality in the high background radiation areas of Yangjiang, China during the period between 1979 and 1995. J Radiat Res. 41(Suppl.):31–41.
  • Tao Z, Akiba S, Zha Y, Sun Q, Zou J, Li J, Liu Y, Yuan Y, Tokonami S, Morishima H, et al. 2012. Cancer and non-cancer mortality among inhabitants in the high background radiation area of Yangjiang, China (1979–1998). Health Phys. 102:173–181.
  • Thierry-Chef I, Richardson DB, Daniels RD, Gillies M, Hamra GB, Haylock R, Kesminiene A, Laurier D, Leuraud K, Moissonnier M, et al. 2015. Dose estimation for a study of nuclear workers in France, the United Kingdom and the United States of America: methods for the International Nuclear Workers Study. Radiat Res. 183:632–642.
  • United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR). 2008. Sources and effects of atomic radiation. Annex A: epidemiological studies of radiation and cancer. In: Effects of ionizing radiation: UNSCEAR 2006 report. Vol. 1. New York: UN; pp. 13–322.
  • United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR). 2015. UNSCEAR 2012 report to the general assembly, with scientific annexes. New York: UN.
  • Vasilenko EK, Khokhryakov VF, Miller SC, Fix JJ, Eckerman K, Choe DO, Gorelov M, Khokhryakov VV, Knyasev V, Krahenbuhl MP, et al. 2007a. Mayak worker dosimetry study: an overview. Health Phys. 93:190–206.
  • Vasilenko EK, Knyazev V, Gorelov M, Smetanin M, Scherpelz RI, Fix JJ. 2007b. Mayak film dosimeter response studies, part 1: measurements. Health Phys. 93:220–230.
  • Vrijheid M, Cardis E, Blettner M, Gilbert E, Hakama M, Hill C, Howe G, Kaldor J, Muirhead CR, Schubauer-Berigan M, et al. 2007. The 15-country Collaborative Study of cancer risk among radiation workers in the nuclear industry: design, epidemiological methods and descriptive results. Radiat Res. 167:361–379.
  • Wiggs LD, Johnson E, Cox-DeVore C, Voelz G. 1994. Mortality through 1990 among white male workers at the Los Alamos National Laboratory: considering exposures to plutonium and external ionizing radiation. Health Phys. 67:577–588.
  • Zablotska LB, Ashmore JP, Howe GR. 2004. Analysis of mortality among Canadian nuclear power industry workers after chronic low-dose exposure to ionizing radiation. Radiat Res. 161:633–641.
  • Zablotska LB, Lane RS, Frost SE. 2013a. Mortality (1950–1999) and cancer incidence (1969–1999) of workers in the Port Hope cohort study exposed to a unique combination of radium, uranium and gamma-ray doses. BMJ Open. 3:e002159.
  • Zablotska LB, Lane RSD, Thompson PA. 2013b. A reanalysis of cancer mortality in Canadian nuclear workers (1956–1994) based on revised exposure and cohort data. Br J Cancer. 110:214–223.
  • Zankl M. 1999. Personal dose equivalent for photons and its variation with dosimeter position. Health Phys. 76:162–170.
  • Zielinski JM, Garner MJ, Band PR, Krewshi D, Shilnikova NS, Jiang H, Ashmore JP, Sont WN, Fair ME, Letourneau EG, et al. 2009. Health outcomes of low-dose ionizing radiation exposure among medical workers: a cohort study of the Canadian National Dose Registry of Radiation Workers. Int J Occup Med Environ Health. 22:149–156.

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