Synergistic effect of Ebselen and gamma radiation on breast cancer cells

References

• Arepalli SK, Choi M, Jung JK, Lee H. 2015. Novel NF-κB inhibitors: a patent review (2011–2014). Expert Opin Ther Pat. 25:319–334.
   PubMed Web of Science ®Google Scholar
• Azad GK, Singh V, Mandal P, Singh P, Golla U, Baranwal S, Chauhan S, Tomar RS. 2014. Ebselen induces reactive oxygen species (ROS)-mediated cytotoxicity in Saccharomyces cerevisiae with inhibition of glutamate dehydrogenase being a target. FEBS Open Bio. 4:77–89.
   PubMed Web of Science ®Google Scholar
• Azad GK, Tomar RS. 2014. Ebselen, a promising antioxidant drug: mechanisms of action and targets of biological pathways. Mol Biol Rep. 41:4865–4879.
   PubMed Web of Science ®Google Scholar
• Cat B, Stuhlmann D, Steinbrenner H, Alili L, Holtkötter O, Sies H, Brenneisen P. 2006. Enhancement of tumor invasion depends on transdifferentiation of skin fibroblasts mediated by reactive oxygen species. J Cell Sci. 119:2727–2738.
   PubMed Web of Science ®Google Scholar
• Christian F, Smith EL, Carmody RJ. 2016. The regulation of NF-κB subunits by phosphorylation. Cells. 5:12–31.
   PubMed Web of Science ®Google Scholar
• Corre I, Guillonneau M, Paris F. 2013. Membrane signaling induced by high doses of ionizing radiation in the endothelial compartment. relevance in radiation toxicity. Int J Mol Sci. 14:22678–22696.
   PubMed Web of Science ®Google Scholar
• Dennert G, Zwahlen M, Brinkman M, Vinceti M, Zeegers MP, Horneber M. 2011. Selenium for preventing cancer. Cochrane Database Syst Rev. 5:CD005195.
   PubMed Web of Science ®Google Scholar
• Di Maggio FM, Minafra L, Forte GI, Cammarata FP, Lio D, Messa C, Gilardi MC, Bravatà V. 2015. Portrait of inflammatory response to ionizing radiation treatment. J Inflamm (Lond). 12:14.
   PubMed Web of Science ®Google Scholar
• Elmore S. 2007. Apoptosis: a review of programmed cell death. Toxicol Pathol. 35:495–516.
   PubMed Web of Science ®Google Scholar
• Freund A, Orjalo AV, Desprez PY, Campisi J. 2010. Inflammatory networks during cellular senescence: causes and consequences. Trends Mol Med. 16:238–246.
   PubMed Web of Science ®Google Scholar
• Gaffen SL, Liu KD. 2004. Overview of interleukin-2 function, production and clinical applications. Cytokine. 28:109–123.
   PubMed Web of Science ®Google Scholar
• Golden EB, Apetoh L. 2015. Radiotherapy and immunogenic cell death. Semin Radiat Oncol. 25:11–17.
   PubMed Web of Science ®Google Scholar
• Hamidullah Changkija B, Konwar R. 2012. Role of interleukin-10 in breast cancer. Breast Cancer Res Treat. 133:11–21.
   PubMed Web of Science ®Google Scholar
• Hoesel B, Schmid JA. 2013. The complexity of NF-κB signaling in inflammation and cancer. Mol Cancer. 12:86.
   PubMed Web of Science ®Google Scholar
• Hossain K, Akhand A, Kato M, Due J, Takeda K, Wu J, Takeuchi K, Liu W, Suzuki H, Nakashima L. 2000. Arsenite induces apoptosis of murine T lymphocytes through membrane raft-linked signaling for activation of c-Jun amino-terminal kinase. J Immunol. 165:4290–4297.
   PubMed Web of Science ®Google Scholar
• Jamier V, Ba LA, Jacob C. 2010. Selenium- and tellurium-containing multifunctional redox agents as biochemical redox modulators with selective cytotoxicity. Chemistry. 16:10920–10928.
   PubMed Web of Science ®Google Scholar
• Karin M, Cao Y, Greten FR, Li ZW. 2002. NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer. 2:301–310.
   PubMed Web of Science ®Google Scholar
• Koyanagi T, Nakamuta M, Enjoji M, Iwamoto H, Motomura K, akai H, Nawata H. 2001. The selenoorganic compound Ebselen suppresses liver injury induced by Propionibacterium acnes and lipopolysaccharide in rats. Int J Mol Med. 7:321–327.
   PubMed Web of Science ®Google Scholar
• Lawrence T. 2009. The Nuclear Factor NF-kappaB pathway in inflammation . Cold Spring Harb Perspect Biol. 1:a001651.
   PubMed Web of Science ®Google Scholar
• Lin WW, Karin M. 2007. A cytokine-mediated link between innate immunity, inflammation, and cancer. J Clin Invest. 117:1175–1183.
   PubMed Web of Science ®Google Scholar
• Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 22DDCT. Methods. 25:402–408.
   PubMed Web of Science ®Google Scholar
• Mathas S, Lietz A, Janz M, Hinz M, Jundt F, Scheidereit C, Bommert K, Dorken B. 2003. Inhibition of NF-kappaB essentially contributes to arsenic-induced apoptosis. Am Soc Hematol. 102:1028–1034.
   Google Scholar
• Miorelli ST, Rosa RM, Moura DJ, Rocha JC, Lobo LA, Henriques JA, Saffi J. 2008. Antioxidant and anti-mutagenic effects of ebselen in yeast and in cultured mammalian V79 cells. Mutagenesis. 23:93–99.
   PubMed Web of Science ®Google Scholar
• Mosmann T. 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods. 65:55–63.
   PubMed Web of Science ®Google Scholar
• Nishida N, Yano H, Nishida T, Kamura T, Kojiro M. 2006. Angiogenesis in cancer. Vasc Health Risk Manag. 2:213–219.
   PubMedGoogle Scholar
• Sharma V, Tewari R, Sk UH, Joseph C, Sen E. 2008. Ebselen sensitizes glioblastoma cells to Tumor Necrosis Factor (TNFalpha)-induced apoptosis through two distinct pathways involving NF-kappaB downregulation and Fas-mediated formation of death inducing signaling complex. Int J Cancer. 123:2204–2212.
   PubMed Web of Science ®Google Scholar
• Sridharan V, Schoenfeld JD. 2015. Immune effects of targeted radiation therapy for cancer. Discov Med. 19:219–228.
   PubMed Web of Science ®Google Scholar
• Tewari R, Sharma V, Koul N, Ghosh A, Joseph C, Sk UH, Sen E. 2009. Ebselen abrogates TNFalpha induced pro-inflammatory response in glioblastoma. Mol Oncol. 3:77–83.
   PubMed Web of Science ®Google Scholar
• Tiegs G, Küsters S, Künstle G, Hentze H, Kiemer AK, Wendel A. 1998. Ebselen protects mice against T cell-dependent, TNF-mediated apoptotic liver injury. J Pharmacol Exp Ther. 287:1098–1104.
   PubMed Web of Science ®Google Scholar
• Wasser S, Lim GY, Ong CN, Tan CE. 2001. Anti-oxidant ebselen causes the resolution of experimentally induced hepatic fibrosis in rats. J Gastroenterol Hepatol. 16:1244–1253.
   PubMed Web of Science ®Google Scholar
• Weigel MT, Dahmke L, Schem C, Bauerschlag DO, Weber K, Niehoff P, Bauer M, Strauss A, Jonat W, Maass N, et al. 2006. In vitro effects of imatinib mesylate on radiosensitivity and chemosensitivity of breast cancer cells. BMC Cancer. 10:412–426.
   Web of Science ®Google Scholar
• Williams CB, Yeh ES, Soloff AC. 2016. Tumor-associated macrophages: unwitting accomplices in breast cancer malignancy. NPJ Breast Cancer. 2:15025.
   PubMed Web of Science ®Google Scholar
• Yu YC, Yang PM, Chuah QY, Huang YH, Peng CW, Lee YJ, Chiu SJ. 2013. Radiation-induced senescence in securin-deficient cancer cells promotes cell invasion involving the IL-6/STAT-3 and PDGF-BB/PDGFR pathways. Sci Rep. 3:1675–1686.
   PubMed Web of Science ®Google Scholar
• Zhang J, Chen Y, Xin XL, Li QN, Li M, Lin LP, Geng MY, Ding J. 2010. Oligomannurarate sulfate blocks tumor growth by inhibiting NF-kappaB activation. Acta Pharmacol Sin. 31:375–381.
   PubMed Web of Science ®Google Scholar
• Zhang L, Zhou L, Du J, Li M, Qian C, Cheng Y, Peng Y, Xie J, Wang D. 2014. Induction of apoptosis in human multiple myeloma cell lines by Ebselen via enhancing the endogenous reactive oxygen species production. BioMed Res Int. 2014:696107.
   PubMedGoogle Scholar