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Original Articles

A scanning and image processing system with integrated design for automated micronucleus scoring

ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon & ORCID Icon
Pages 628-641 | Received 08 Jul 2019, Accepted 01 Jan 2020, Published online: 07 Feb 2020

References

  • Ainsbury EA, Bakhanova E, Barquinero JF, Brai M, Chumak V, Correcher V, Darroudi F, Fattibene P, Gruel G, Guclu I, et al. 2011. Review of retrospective dosimetry techniques for external ionising radiation exposures. Radiat Prot Dosimetry. 147(4):573–592.
  • Ainsbury EA, Higueras M, Puig P, Einbeck J, Samaga D, Barquinero JF, Barrios L, Brzozowska B, Fattibene P, Gregoire E, et al. 2016. Uncertainty of fast biological radiation dose assessment for emergency response scenarios. Int J Radiat Biol. 93(1):127–135.
  • Ainsbury EA, Lloyd DC. 2010. Dose estimation software for radiation biodosimetry. Health Phys. 98(2):290–295.
  • Beinke C, Barnard S, Amicis AD, Sanctis SD, Herodin F, Valente M, Meineke V, Little MP, Abend M. 2012. Performance of the dicentric assay in a recent NATO exercise of established and emerging biodosimetry methods. 13th IRPA (International Radiation Protection Association) International Congress. p. 1–10. http://www.irpa.net/members/TS2c.2.pdf.
  • Bian D, Tsui JC, Repin M, Garty G, Turner H, Lawrence Yao Y, Brenner DJ. 2016. Liquid handling optimization in high-throughput biodosimetry tool. J Med Device. 10(4):0410071–4100710.
  • BIPM Joint Committee for Guides in Metrology. 2008. Evaluation of measurement data — guide to the expression of uncertainty in measurement. Organ Stand Geneva ISBN. 50(Sept):134.
  • Bolognesi C, Balia C, Roggieri P, Cardinale F, Bruzzi P, Sorcinelli F, Lista F, D’Amelio R, Righi E. 2011. Micronucleus test for radiation biodosimetry in mass casualty events: evaluation of visual and automated scoring. Radiat Meas. 46(2):169–175.
  • Brzozowska B, Ainsbury E, Baert A, Beaton-Green L, Barrios L, Barquinero JF, Bassinet C, Beinke C, Benedek A, Beukes P, et al. 2016. RENEB accident simulation exercise. Int J Radiat Biol. 93(1):1–6.
  • Castelain P, Van Hummelen P, Deleener A, Kirsch-Volders M. 1993. Automated detection of cytochalasin-B blocked binucleated lymphocytes for scoring micronuclei. Mutagenesis. 8(4):285–293.
  • De Sanctis S, De Amicis A, Di Cristofaro S, Franchini V, Regalbuto E, Mammana G, Lista F. 2014. Cytokinesis-block micronucleus assay by manual and automated scoring: calibration curves and dose prediction. Health Phys. 106(6):745–749.
  • Decordier I, Papine A, Plas G, Roesems S, Vande Loock K, Moreno-Palomo J, Cemeli E, Anderson D, Fucic A, Marcos R, et al. 2009. Automated image analysis of cytokinesis-blocked micronuclei: an adapted protocol and a validated scoring procedure for biomonitoring. Mutagenesis. 24(1):85–93. doi:10.1093/mutage/gen057
  • Decordier I, Papine A, Vande Loock K, Plas G, Soussaline F, Kirsch-Volders M. 2011. Automated image analysis of micronuclei by IMSTAR for biomonitoring. Mutagenesis. 26(1):163–168.
  • Fenech M. 2000. The in vitro micronucleus technique. Mutat Res Mol Mech Mutagen. 455(1–2):81–95.
  • Fenech M, Kirsch-Volders M, Rossnerova A, Sram R, Romm H, Bolognesi C, Ramakumar A, Soussaline F, Schunck C, Elhajouji A, et al. 2013. HUMN project initiative and review of validation, quality control and prospects for further development of automated micronucleus assays using image cytometry systems. Int J Hyg Environ Health. 216(5):541–552.
  • Frieauff W, Martus HJ, Suter W, Elhajouji A. 2013. Automatic analysis of the micronucleus test in primary human lymphocytes using image analysis. Mutagenesis. 28(1):15–23.
  • Garty G, Chen Y, Salerno A, Turner H, Zhang J, Lyulko O, Bertucci A, Xu Y, Wang H, Simaan N, et al. 2010. The RABIT: a rapid automated biodosimetry tool for radiological triage. Health Phys. 98(2):209–217.
  • Garty G, Chen Y, Turner HC, Zhang J, Lyulko OV, Bertucci A, Xu Y, Wang H, Simaan N, Randers-Pehrson G, et al. 2011. The RABiT: a rapid automated biodosimetry tool for radiological triage. II. Technological developments. Int J Radiat Biol. 87(8):776–790.
  • Hulber E. 2009. Overview of PADC nuclear track readers. Recent trends and solutions. Radiat Meas. 44(9–10):821–825.
  • Iarmarcovai G, Ceppi M, Botta A, Orsière T, Bonassi S. 2008. Micronuclei frequency in peripheral blood lymphocytes of cancer patients: a meta-analysis. Mutat Res. 659(3):274–283.
  • International Atomic Energy Agency (IAEA). 2011. Cytogenetic dosimetry: applications in preparedness for and response to radiation emergencies. Vienna: IAEA. https://www.iaea.org/publications/8735/cytogenetic-dosimetry-applications-in-preparedness-for-and-response-to-radiation-emergencies.
  • Lloyd DC, Edwards AA, Szłuińska M. 2006. The minimum detectable dose by biodosimetry in a radiation overexposure. In: Cigna AA, Durante M, editors. Radiation risk estimates in normal and emergency situations. NATO Security through Science Series. Dordrecht: Springer. doi:10.1007/1-4020-4956-0_25
  • Lyulko O V, Garty G, Randers-Pehrson G, Turner HC, Szolc B, Brenner DJ. 2014. Fast image analysis for the micronucleus assay in a fully automated high-throughput biodosimetry system. Radiat Res. 181(2):146–161.
  • Maes A, Hond E, Vershaeve L. 2007. Automated image analysis of micronuclei in binucleated human lymphocytes. Microsc Anal. 21(1):7–9.
  • Repin M, Pampou S, Garty G, Brenner DJ. 2019. RABiT-II: a fully-automated micronucleus assay system with shortened time to result. Radiat Res. 191(3):232.
  • Romm H, Barnard S. 2013. Laboratory intercomparison of the cytokinesis-block micronucleus assay. Radiat Res. 180(2):120–128.
  • Rossnerova A, Spatova M, Rossner P, Solansky I, Sram RJ. 2009. The impact of air pollution on the levels of micronuclei measured by automated image analysis. Mutat Res Fundam Mol Mech Mutagen. 669(1–2):42–47.
  • Rossnerova A, Spatova M, Schunck C, Sram RJ. 2011. Automated scoring of lymphocyte micronuclei by the MetaSystems Metafer image cytometry system and its application in studies of human mutagen sensitivity and biodosimetry of genotoxin exposure. Mutagenesis. 26(1):169–175.
  • Seimetz M, Bellido P, García P, Mur P, Iborra A, Soriano A, Hülber T, García López J, Jiménez-Ramos MC, Lera R, et al. 2018. Spectral characterization of laser-accelerated protons with CR-39 nuclear track detector. Rev Sci Instrum. 89(2):023302.
  • Smereka M, Dulęba I. 2008. Circular object detection using a modified Hough transform. Int J Appl Math Comput Sci. 18(1):85–91.
  • Sullivan JM, Prasanna PGS, Grace MB, Wathen LK, Wallace RL, Koerner JF, Coleman CN. 2013. Assessment of biodosimetry methods for a mass-casualty radiological incident: medical response and management considerations. Health Phys. 105(6):540–554.
  • Tamizh Selvan G, Chaudhury NK, Venkatachalam P. 2015. Comparison of results of the manual and automated scoring of micronucleus frequencies in 60Co-irradiated peripheral blood lymphocytes for triage dosimetry. Appl Radiat Isot. 97(Aug):70–77.
  • Varga D, Johannes T, Jainta S, Schuster S, Schwarz BU, Kiechle M, Patino GB, Vogel W. 2004. An automated scoring procedure for the micronucleus test by image analysis. Mutagenesis. 19(5):391–397.
  • Verhaegen F, Vral A, Seuntjens J, Schipper NW, de Ridder L, Thierens H. 1994. Scoring of radiation-induced microuclei in cytokinesis-blocked human lymphocytes by automated image analysis. Cytometry. 17(2):119–127.
  • Vral A, Fenech M, Thierens H. 2011. The micronucleus assay as a biological dosimeter of in vivo ionising radiation exposure. Mutagenesis. 26(1):11–17.
  • Willems P, August L, Slabbert J, Romm H, Oestreicher U, Thierens H, Vral A. 2010. Automated micronucleus (MN) scoring for population triage in case of large scale radiation events. Int J Radiat Biol. 86(1):2–11.

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