291
Views
3
CrossRef citations to date
0
Altmetric
Original Articles

Suppression of innate immune signaling molecule, MAVS, reduces radiation-induced bystander effect

, , , &
Pages 102-110 | Received 11 Mar 2020, Accepted 30 Jul 2020, Published online: 20 Aug 2020

References

  • Aten JA, Stap J, Krawczyk PM, van Oven CH, Hoebe RA, Essers J, Kanaar R. 2004. Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains. Science. 303:92–95.
  • Azzam EI, Jay-Gerin JP, Pain D. 2012. Ionizing radiation-induced metabolic oxidative stress and prolonged cell injury. Cancer Lett. 327:48–60.
  • Banoth B, Cassel SL. 2018. Mitochondria in innate immune signaling. Translat Res. 202:52–68.
  • Buskiewicz IA, Montgomery T, Yasewicz EC, Huber SA, Murphy MP, Hartley RC, Kelly R, Crow MK, Perl A, Budd RC, et al. 2016. Reactive oxygen species induce virus-independent MAVS oligomerization in systemic lupus erythematosus. Sci Signal. 9:ra115.
  • Castanier C, Zemirli N, Portier A, Garcin D, Bidere N, Vazquez A, Arnoult D. 2012. MAVS ubiquitination by the E3 ligase TRIM25 and degradation by the proteasome is involved in type I interferon production after activation of the antiviral RIG-I-like receptors. BMC Biol. 10:44.
  • Clutton S. 1997. The importance of oxidative stress in apoptosis. Br Med Bull. 53:662–668.
  • d'Adda di Fagagna F, Reaper PM, Clay-Farrace L, Fiegler H, Carr P, Von Zglinicki T, Saretzki G, Carter NP, Jackson SP. 2003. A DNA damage checkpoint response in telomere-initiated senescence. Nature. 426:194–198.
  • Du Y, Pan D, Jia R, Chen Y, Jia C, Wang J, Hu B. 2020. The reduced oligomerization of MAVS mediated by ROS enhances the cellular radioresistance. Oxid Med Cell Longev. 2020:2167129.
  • Edwards GO, Botchway SW, Hirst G, Wharton CW, Chipman JK, Meldrum RA. 2004. Gap junction communication dynamics and bystander effects from ultrasoft X-rays. Br J Cancer. 90:1450–1456.
  • Huang Y, Liu H, Li S, Tang Y, Wei B, Yu H, Wang C. 2014. MAVS-MKK7-JNK2 defines a novel apoptotic signaling pathway during viral infection. PLoS Pathog. 10:e1004020.
  • Ivanov VN, Zhou H, Ghandhi SA, Karasic TB, Yaghoubian B, Amundson SA, Hei TK. 2010. Radiation-induced bystander signaling pathways in human fibroblasts: a role for interleukin-33 in the signal transmission. Cell Signal. 22:1076–1087.
  • Lei Y, Moore CB, Liesman RM, O'Connor BP, Bergstralh DT, Chen ZJ, Pickles RJ, Ting JP. 2009. MAVS-mediated apoptosis and its inhibition by viral proteins. PLoS One. 4:e5466.
  • Little JB. 2003. Genomic instability and bystander effects: a historical perspective. Oncogene. 22:6978–6987.
  • Liu F, Gu J. 2011. Retinoic acid inducible gene-I, more than a virus sensor. Protein Cell. 2:351–357.
  • Loo YM, Gale M. Jr. 2011. Immune signaling by RIG-I-like receptors. Immunity. 34:680–692.
  • Morgan WF. 2012. Non-targeted and delayed effects of exposure to ionizing radiation: I. Radiation-induced genomic instability and bystander effects in vitro. 2003. Radiat Res. 178:AV223–AV236.
  • Mothersill C, Seymour C. 1997. Survival of human epithelial cells irradiated with cobalt 60 as microcolonies or single cells. Int J Radiat Biol. 72:597–606.
  • Mothersill C, Seymour CB. 2004. Radiation-induced bystander effects – implications for cancer. Nat Rev Cancer. 4:158–164.
  • Nagasawa H, Little JB. 1992. Induction of sister chromatid exchanges by extremely low doses of alpha-particles. Cancer Research. 52:6394–6396.
  • Ramesh R, Marrogi AJ, Munshi A, Abboud CN, Freeman SM. 1996. In vivo analysis of the ‘bystander effect’: a cytokine cascade. Exp Hematol. 24:829–838.
  • Ranoa DR, Parekh AD, Pitroda SP, Huang X, Darga T, Wong AC, Huang L, Andrade J, Staley JP, Satoh T, et al. 2016. Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs. Oncotarget. 7:26496–26515.
  • Rout AK, Udgata SR, Dehury B, Pradhan SP, Swain HS, Behera BK, Das BK. 2019. Structural bioinformatics insights into the CARD-CARD interaction mediated by the mitochondrial antiviral-signaling protein of black carp. J Cell Biochem. 120:12534–12543.
  • Scott I. 2010. The role of mitochondria in the mammalian antiviral defense system. Mitochondrion. 10:316–320.
  • Shao C, Lyng FM, Folkard M, Prise KM. 2006. Calcium fluxes modulate the radiation-induced bystander responses in targeted glioma and fibroblast cells. Radiat Res. 166:479–487.
  • Wan XS, Zhou Z, Ware JH, Kennedy AR. 2005. Standardization of a fluorometric assay for measuring oxidative stress in irradiated cells. Radiat Res. 163:232–240.
  • Wang R, Coderre JA. 2005. A bystander effect in alpha-particle irradiations of human prostate tumor cells. Radiat Res. 164:711–722.
  • Wang X, Zhang J, Fu J, Wang J, Ye S, Liu W, Shao C. 2015. Role of ROS-mediated autophagy in radiation-induced bystander effect of hepatoma cells. Int J Radiat Biol. 91:452–458.
  • Widel M, Lalik A, Krzywon A, Poleszczuk J, Fujarewicz K, Rzeszowska-Wolny J. 2015. The different radiation response and radiation-induced bystander effects in colorectal carcinoma cells differing in p53 status. Mutat Res. 778:61–70.
  • Yoneyama M, Fujita T. 2009. RNA recognition and signal transduction by RIG-I-like receptors. Immunol Rev. 227:54–65.
  • Yoneyama M, Kikuchi M, Natsukawa T, Shinobu N, Imaizumi T, Miyagishi M, Taira K, Akira S, Fujita T. 2004. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat Immunol. 5:730–737.
  • Zhang D, Zhou T, He F, Rong Y, Lee SH, Wu S, Zuo L. 2016. Reactive oxygen species formation and bystander effects in gradient irradiation on human breast cancer cells. Oncotarget. 7:41622–41636.
  • Zhou Z, Jia X, Xue Q, Dou Z, Ma Y, Zhao Z, Jiang Z, He B, Jin Q, Wang J. 2014. TRIM14 is a mitochondrial adaptor that facilitates retinoic acid-inducible gene-I-like receptor-mediated innate immune response. Proc Natl Acad Sci USA. 111:E245–E254.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.