The sine qua non of the fish invitrome today and tomorrow in environmental radiobiology

References

• Azzam EI, de Toledo SM, Little JB. 2001. Direct evidence for the participation of gap junction-mediated intercellular communication in the transmission of damage signals from alpha-particle irradiated to nonirradiated cells. Proc Natl Acad Sci U S A. 98:473–478.
   PubMed Web of Science ®Google Scholar
• Babich H, Shopsis C, Borenfreund E. 1986. In vitro cytotoxicity testing of aquatic pollutants (cadmium, copper, zinc, nickel) using established fish cell lines. Ecotoxicol Environ Saf. 11:91–99.
   PubMed Web of Science ®Google Scholar
• Bairoch A. 2018. The cellosaurus, a cell-line knowledge resource. Version 2. J Biomol Tech. 29:25–38.
   PubMedGoogle Scholar
• Belisheva NK, Lammer H, Biernat HK, Vashenuyk EV. 2012. The effect of cosmic rays on biological systems – an investigation during GLE events. Astrophys Space Sci Trans. 8:7–17.
   Google Scholar
• Belova NV, Emel’yanova NG, Makeeva AP, Ryabov IN. 2007. The state of the reproductive system of several fish species from water bodies polluted with radionuclides during the Chernobyl catastrophe. J Ichthyol. 47:366–384.
   Google Scholar
• Bjerkås E, Holst JC, BjerkåS I, 2004. Cataract in farmed and wild Atlantic salmon (Salmo salar L.). Anim Eye Res. 23:3–13.
   Google Scholar
• Björnsson B. 2004. Can UV-treated seawater cause cataract in juvenile cod (Gadus morhua L.)? Aquaculture. 240:187–199.
   Web of Science ®Google Scholar
• Bols NC, Pham PH, Dayeh VR, Lee LEJ. 2017. Invitromatics, invitrome, and invitroomics: introduction of three new terms for in vitro biology and illustration of their use with the cell lines from rainbow trout. In Vitro Cell Dev Biol Anim. 53:383–405.
   PubMed Web of Science ®Google Scholar
• Cassidy CL, Lemon JA, Boreham DR. 2007. Impacts of low-dose gamma-radiation on genotoxic risk in aquatic ecosystems. Dose Response. 5:323–332.
   PubMedGoogle Scholar
• Chen S, Hong Y, Scherer SJ, Schartl M. 2001. Lack of ultraviolet-light inducibility of the medakafish (Oryzias latipes) tumor suppressor gene p53. Gene. 264:197–203.
   PubMed Web of Science ®Google Scholar
• Choi VW, Konishi T, Oikawa M, Iso H, Cheng SH, Yu KN. 2010. Adaptive response in zebrafish embryos induced using microbeam protons as priming dose and X-ray photons as challenging dose. J Radiat Res. 51:657–664.
   PubMed Web of Science ®Google Scholar
• Cohen J, Vo NTK, Chettle D, McNeill FE, Seymour CB, Mothersill CE. 2020. Quantifying biophoton emissions from human cells directly exposed to low-dose gamma radiation. Dose Response. 18:1559325820926763.
   Web of Science ®Google Scholar
• Cohen J, Vo NTK, Seymour CB, Mothersill CE. 2019. Parallel comparison of pre-conditioning and post-conditioning effects in human cancers and keratinocytes upon acute gamma irradiation. Int J Radiat Biol. 95:170–178.
   PubMed Web of Science ®Google Scholar
• Costa SR, Velasques RR, Hoff MLM, Souza MM, Sandrini JZ. 2019. Characterization of different DNA repair pathways in hepatic cells of Zebrafish (Danio rerio). DNA Repair (Amst). 83:102695.
   PubMed Web of Science ®Google Scholar
• Curtis JJ, Vo NTK, Seymour CB, Mothersill CE. 2020. 5-HT2A and 5-HT3 receptors contribute to the exacerbation of targeted and non-targeted effects of ionizing radiation-induced cell death in human colon carcinoma cells. Int J Radiat Biol. 96:482–490.
   PubMed Web of Science ®Google Scholar
• Curtis TM, Collins AM, Gerlach BD, Brennan LM, Widder MW, van der Schalie WH, Vo NTK, Bols NC. 2013. Suitability of invertebrate and vertebrate cells in a portable impedance-based toxicity sensor: temperature mediated impacts on long-term survival. Toxicol In Vitro. 27:2061–2066.
   PubMed Web of Science ®Google Scholar
• Dowling K, Seymour C, Mothersill C. 2005. Delayed cell death and bystander effects in the progeny of Chinook salmon embryo cells exposed to radiation and a range of aquatic pollutants. Int J Radiat Biol. 81:89–96.
   PubMed Web of Science ®Google Scholar
• Fan Z, Liu L, Huang X, Zhao Y, Zhou L, Wang D, Wei J. 2017. Establishment and growth responses of Nile tilapia embryonic stem-like cell lines under feeder-free condition. Dev Growth Differ. 59:83–93.
   PubMed Web of Science ®Google Scholar
• Garnier-Laplace J, Geras'kin S, Della-Vedova C, Beaugelin-Seiller K, Hinton TG, Real A, Oudalova A. 2013. Are radiosensitivity data derived from natural field conditions consistent with data from controlled exposures? A case study of Chernobyl wildlife chronically exposed to low dose rates. J Environ Radioact. 121:12–21.
   PubMed Web of Science ®Google Scholar
• Gattuso A, Garofalo F, Cerra MC, Imbrogno S. 2018. Hypoxia tolerance in teleosts: implications of cardiac nitrosative signals. Front Physiol. 9:366.
   PubMed Web of Science ®Google Scholar
• Glasauer SM, Neuhauss SC. 2014. Whole-genome duplication in teleost fishes and its evolutionary consequences. Mol Genet Genomics. 289:1045–1060.
   PubMed Web of Science ®Google Scholar
• Graf M, Hartmann N, Reichwald K, Englert C. 2013. Absence of replicative senescence in cultured cells from the short-lived killifish Nothobranchius furzeri. Exp Gerontol. 48:17–28.
   PubMed Web of Science ®Google Scholar
• Hall EJ, Giaccia AJ. 2006. Radiobiology for the radiologist. 6th ed. Philadelphia (PA): Lippincott Williams & Wilkins.
   Google Scholar
• Hancock S, Vo NTK, Byun SH, Zainullin VG, Seymour CB, Mothersill CE. 2019a. Effects of historic radiation dose on the frequency of sex-linked recessive lethals in Drosophila populations following the Chernobyl nuclear accident. Environ Res. 172:333–337.
   PubMed Web of Science ®Google Scholar
• Hancock S, Vo NTK, Goncharova RI, Seymour CB, Byun SH, Mothersill CE. 2020. One-decade-spanning transgenerational effects of historic radiation dose in wild populations of bank voles exposed to radioactive contamination following the Chernobyl nuclear disaster. Environ Res. 180:108816.
   PubMed Web of Science ®Google Scholar
• Hancock S, Vo NTK, Omar-Nazir L, Batlle JVI, Otaki JM, Hiyama A, Byun SH, Seymour CB, Mothersill C. 2019b. Transgenerational effects of historic radiation dose in pale grass blue butterflies around Fukushima following the Fukushima Dai-ichi nuclear power plant meltdown accident. Environ Res. 168:230–240.
   PubMed Web of Science ®Google Scholar
• Hartmann N, Reichwald K, Lechel A, Graf M, Kirschner J, Dorn A, Terzibasi E, Wellner J, Platzer M, Rudolph KL, et al. 2009. Telomeres shorten while Tert expression increases during ageing of the short-lived fish Nothobranchius furzeri. Mech Ageing Dev. 130:290–296.
   PubMed Web of Science ®Google Scholar
• Harvey DM, Levine AJ. 1991. p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts. Genes Dev. 5:2375–2385.
   PubMed Web of Science ®Google Scholar
• Hollstein M, Sidransky D, Vogelstein B, Harris CC. 1991. p53 mutations in human cancers. Science. 253:49–53.
   PubMed Web of Science ®Google Scholar
• Hong N, Li Z, Hong Y. 2011. Fish stem cell cultures. Int J Biol Sci. 7:392–402.
   PubMed Web of Science ®Google Scholar
• Hurem S, Martín LM, Lindeman L, Brede DA, Salbu B, Lyche JL, Aleström P, Kamstra JH. 2018. Parental exposure to gamma radiation causes progressively altered transcriptomes linked to adverse effects in zebrafish offspring. Environ Pollut. 234:855–863.
   PubMed Web of Science ®Google Scholar
• Imanaka T, Hayashi G, Endo S. 2015. Comparison of the accident process, radioactivity release and ground contamination between Chernobyl and Fukushima-1. J Radiat Res. 56:i56–i61.
   PubMed Web of Science ®Google Scholar
• International Atomic Energy Agency (IAEA). 2013. INES: The International Nuclear and Radiological Event Scale User’s Manual. [accessed 2020 May 23]. https://www-pub.iaea.org/MTCD/Publications/PDF/INES2013web.pdf
   Google Scholar
• International Union for Conservation of Nature and Natural Resources (IUCN). 2020. The IUCN Red List of Threatened Species. Version 2020-1. Table 1a “Number of species evaluated in relation to the overall number of described species, and numbers of threatened species by major groups of organisms”. [accessed 2020 May 24]. https://www.iucnredlist.org/resources/summary-statistics#Summary%20Tables
   Google Scholar
• Kamstra JH, Hurem S, Martin LM, Lindeman LC, Legler J, Oughton D, Salbu B, Brede DA, Lyche JL, Aleström P. 2018. Ionizing radiation induces transgenerational effects of DNA methylation in zebrafish. Sci Rep. 8:15373.
   PubMed Web of Science ®Google Scholar
• Krause MK, Rhodes LD, Van Beneden RJ. 1997. Cloning of the p53 tumor suppressor gene from the Japanese medaka (Oryzias latipes) and evaluation of mutational hotspots in MNNG-exposed fish. Gene. 189:101–106.
   PubMed Web of Science ®Google Scholar
• Kurihara Y, Rienkjkarn M, Etoh H. 1992. Cytogenetic adaptive response of cultured fish cells to low doses of X-rays. J Radiat Res. 33:267–274.
   PubMed Web of Science ®Google Scholar
• Lane DP. 1992. Cancer. p53, guardian of the genome. Nature. 358:15–16.
   PubMed Web of Science ®Google Scholar
• Laskowski L, Williams D, Seymour C, Mothersill C. 2020. Environmental and industrial developments in radiation cataractogenesis. Int J Radiat Biol.
   PubMed Web of Science ®Google Scholar
• Laycock NLC, Schirmer K, Bols NC, Sivak JG. 2000. Optical properties of rainbow trout lenses after in vitro exposure to polycyclic aromatic hydrocarbons in the presence or absence of ultraviolet radiation. Exp Eye Res. 70:205–214.
   PubMed Web of Science ®Google Scholar
• Le M, Fernandez-Palomo C, McNeill FE, Seymour CB, Rainbow AJ, Mothersill CE. 2017. Exosomes are released by bystander cells exposed to radiation-induced biophoton signals: reconciling the mechanisms mediating the bystander effect. PLoS One. 12:e0173685.
   PubMed Web of Science ®Google Scholar
• Le M, McNeill FE, Seymour C, Rainbow AJ, Mothersill CE. 2015. An observed effect of ultraviolet radiation emitted from beta-irradiated HaCaT cells upon non-beta-irradiated bystander cells. Radiat Res. 183:279–290.
   PubMed Web of Science ®Google Scholar
• Lee JM, Bernstein A. 1993. p53 mutations increase resistance to ionizing radiation. Proc Natl Acad Sci U S A. 90:5742–5746.
   PubMed Web of Science ®Google Scholar
• Lehman TA, Modali R, Boukamp P, Stanek J, Bennett WP, Welsh JA, Metcalf RA, Stampfer MR, Fusenig N, Rogan EM. 1993. p53 mutations in human immortalized epithelial cell lines. Carcinogenesis. 14:833–839.
   PubMed Web of Science ®Google Scholar
• Lerebours A, Gudkov D, Nagorskaya L, Kaglyan A, Rizewski V, Leshchenko A, Bailey EH, Bakir A, Ovsyanikova S, Laptev G, et al. 2018. Impact of environmental radiation on the health and reproductive status of fish from chernobyl. Environ Sci Technol. 52:9442–9450.
   PubMed Web of Science ®Google Scholar
• Li Z. 2019. Effects of temperature on the proliferation of human and fish lens epithelial cells [master’s thesis]. Waterloo (ON): University of Waterloo.
   Google Scholar
• Liu M, Tee C, Zeng F, Sherry JP, Dixon B, Bols NC, Duncker BP. 2011. Characterization of p53 expression in rainbow trout. Comp Biochem Physiol C Toxicol Pharmacol. 154:326–332.
   PubMed Web of Science ®Google Scholar
• Lyng FM, Seymour CB, Mothersill C. 2002. Early events in the apoptotic cascade initiated in cells treated with medium from the progeny of irradiated cells. Radiat Prot Dosimetry. 99:169–172.
   PubMed Web of Science ®Google Scholar
• Mitani H. 1983. Lethal and mutagenic effects of radiation and chemicals on cultured fish cells derived from the erythrophoroma of goldfish (Carassius auratus). Mutat Res. 107:279–288.
   PubMedGoogle Scholar
• Mitani H, Etoh H, Egami N. 1982. Resistance of a cultured fish cell line (CAF-MM1) to γ irradiation. Radiat Res. 89:334–347.
   PubMed Web of Science ®Google Scholar
• Montgomery DW, Simpson SD, Engelhard GH, Birchenough SNR, Wilson RW. 2019. Rising CO2 enhances hypoxia tolerance in a marine fish. Sci Rep. 9:15152.
   PubMed Web of Science ®Google Scholar
• Mothersill C, Bristow RG, Harding SM, Smith RW, Mersov A, Seymour CB. 2011. A role for p53 in the response of bystander cells to receipt of medium borne signals from irradiated cells. Int J Radiat Biol. 87:1120–1125.
   PubMed Web of Science ®Google Scholar
• Mothersill C, Bucking C, Smith RW, Agnihotri N, Oneill A, Kilemade M, Seymour CB. 2006. Communication of radiation-induced stress or bystander signals between fish in vivo. Environ Sci Technol. 40:6859–6864.
   PubMed Web of Science ®Google Scholar
• Mothersill C, Oughton DH, Schofield Pn, Abend M, Adam-Guillermin C, Ariyoshi K, Beresford NA, Bonisoli-Alquati A, Cohen J, Dubrova Y. 2020. From tangled banks to toxic bunnies; a reflection on the issues involved in developing an ecosystem approach for environmental radiation protection. Int J Radiat Biol. DOI: 10.1080/09553002.2020.1793022
   Web of Science ®Google Scholar
• Mothersill C, Rusin A, Seymour C. 2017. Low doses and non-targeted effects in environmental radiation protection; where are we now and where should we go? Environ Res. 159:484–490.
   PubMed Web of Science ®Google Scholar
• Mothersill C, Seymour C. 2019. Targets, pools, shoulders, and communication - a reflection on the evolution of low-dose radiobiology. Int J Radiat Biol. 95:851–860.
   PubMed Web of Science ®Google Scholar
• Murley J, Miller R, Weichselbaum R, Grdina D. 2017. TP53 mutational status and ROS effect the expression of the survivin-associated radio-adaptive response. Radiat Res. 188:659–670.
   Web of Science ®Google Scholar
• O'Neill-Mehlenbacher A, Kilemade M, Elliott A, Mothersill C, Seymour C. 2007. Comparison of direct and bystander effects induced by ionizing radiation in eight fish cell lines. Int J Radiat Biol. 83:593–602.
   PubMed Web of Science ®Google Scholar
• O'Reilly JP, Mothersill C. 1997. Comparative effects of UV A and UV B on clonogenic survival and delayed cell death in skin cell lines from humans and fish. Int J Radiat Biol. 72:111–119.
   PubMed Web of Science ®Google Scholar
• Pereira S, Bourrachot S, Cavalie I, Plaire D, Dutilleul M, Gilbin R, Adam-Guillermin C. 2011. Genotoxicity of acute and chronic gamma-irradiation on zebrafish cells and consequences for embryo development. Environ Toxicol Chem. 30:2831–2837.
   PubMed Web of Science ®Google Scholar
• Pereira S, Malard V, Ravanat JL, Davin AH, Armengaud J, Foray N, Adam-Guillermin C. 2014. Low doses of gamma-irradiation induce an early bystander effect in zebrafish cells which is sufficient to radioprotect cells. PLoS One. 9:e92974.
   PubMed Web of Science ®Google Scholar
• Pham PH, Vo NTK, Tan EJH, Russell S, Jones G, Lumsden JS, Bols NC. 2017. Development of an Atlantic salmon heart endothelial cell line (ASHe) that responds to lysophosphatidic acid (LPA). In Vitro Cell Dev Biol Anim. 53:20–32.
   PubMed Web of Science ®Google Scholar
• Puck TT, Marcus PI. 1956. Action of X-rays on mammalian cells. J Exp Med. 103:653–666.
   PubMed Web of Science ®Google Scholar
• Rau Embry M, Billiard SM, Di Giulio RT. 2006. Lack of p53 induction in fish cells by model chemotherapeutics. Oncogene. 25:2004–2010.
   PubMed Web of Science ®Google Scholar
• Ribeiro JC, Barnetson AR, Fisher RJ, Mameghan H, Russell PJ. 1997. Relationship between radiation response and p53 status in human bladder cancer cells. Int J Radiat Biol. 72:11–20.
   PubMed Web of Science ®Google Scholar
• Ryan LA, Seymour CB, O'Neill-Mehlenbacher A, Mothersill CE. 2008. Radiationinduced adaptive response in fish cell lines. J Environ Radioact. 99:739–747.
   PubMed Web of Science ®Google Scholar
• Ryu JH, Kim MS, Kang JH, Kim DH, Nam YK, Gong SP. 2018. Derivation of the clonal-cell lines from Siberian sturgeon (Acipenser baerii) head-kidney cell lines and its applicability to foreign gene expression and virus culture. J Fish Biol. 92:1273–1289.
   PubMed Web of Science ®Google Scholar
• Saroya R, Smith R, Seymour C, Mothersill C. 2009. Injection of resperpine into zebrafish, prevents fish to fish communication of radiation-induced bystander signals: confirmation in vivo of a role for serotonin in the mechanism. Dose Response. 8:317–330.
   PubMed Web of Science ®Google Scholar
• Sazykina TG, Kryshev AI. 2003. EPIC database on the effects of chronic radiation in fish: Russian/FSU data. J Environ Radioact. 68:65–87.
   PubMed Web of Science ®Google Scholar
• Scholz S, Sela E, Blaha L, Braunbeck T, Galay-Burgos M, García-Franco M, Guinea J, Klüver N, Schirmer K, Tanneberger K, et al. 2013. A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment. Regul Toxicol Pharmacol. 67:506–530.
   PubMed Web of Science ®Google Scholar
• Semple SL, Vo NTK, Li AR, Pham PH, Bols NC, Dixon B. 2017. Development and use of an Arctic charr cell line to study antiviral responses at extremely low temperatures. J Fish Dis. 40:1423–1439.
   PubMed Web of Science ®Google Scholar
• Sever L, Vo NTK, Bols NC, Dixon B. 2014. The rainbow trout (Oncorhynchus mykiss) contain two calnexin genes which encode distinct proteins. Dev Comp Immunol. 42:211–219.
   PubMed Web of Science ®Google Scholar
• Sever L, Vo NTK, Bols NC, Dixon B. 2018. Tapasin’s protein interactions in the rainbow trout peptide-loading complex. Dev Comp Immunol. 81:262–270.
   PubMed Web of Science ®Google Scholar
• Shi X, Mothersill C, Seymour C. 2016a. No adaptive response is induced by chronic low-dose radiation from Ra-226 in the CHSE/F fish embryonic cell line and the HaCaT human epithelial cell line. Environ Res. 151:537–546.
   PubMed Web of Science ®Google Scholar
• Shi X, Seymour C, Mothersill C. 2016b. The effects of chronic, low doses of Ra-226 on cultured fish and human cells. Environ Res. 148:303–309.
   PubMed Web of Science ®Google Scholar
• Shi X, Seymour C, Mothersill C. 2018. Change of cell growth and mitochondrial membrane polarization in the progeny of cells surviving low-dose high-LET irradiation from Ra-226. Environ Res. 167:51–65.
   PubMed Web of Science ®Google Scholar
• Shima A, Setlow RB. 1984. Survival and pyrimidine dimers in cultured fish cells exposed to concurrent sun lamp ultraviolet and photoreactivating radiations. Photochem Photobiol. 39:49–56.
   PubMed Web of Science ®Google Scholar
• Shimada A, Shima A. 2004. Transgenerational genomic instability as revealed by a somatic mutation assay using the medaka fish. Mutat Res. 552:119–124.
   PubMed Web of Science ®Google Scholar
• Smith RW, Seymour CB, Moccia RD, Hinton TG, Mothersill CE. 2013a. The induction of a radiation-induced bystander effect in fish transcends taxonomic group and trophic level. Int J Radiat Biol. 89:225–233.
   PubMed Web of Science ®Google Scholar
• Smith RW, Seymour CB, Mothersill CE. 2013b. Short and long term bystander effect induction by fathead minnows (Pimephales promelas, Rafinesque, 1820) injected with environmentally relevant whole body doses of 226-Ra. J Environ Radioact. 126:133–136.
   PubMed Web of Science ®Google Scholar
• Sreetharan S, Thome C, Tsang KK, Somers CM, Manzon RG, Boreham DR, Wilson JY. 2018. Micronuclei formation in rainbow trout cells exposed to multiple stressors: Morpholine, heat shock, and ionizing radiation. Toxicol In Vitro. 47:38–47.
   PubMed Web of Science ®Google Scholar
• Stuart M, Festarini A, Schleicher K, Tan E, Kim SB, Wen K, Gawlik J, Ulsh B. 2016. Biological effects of tritium on fish cells in the concentration range of international drinking water standards. Int J Radiat Biol. 92:563–571.
   PubMed Web of Science ®Google Scholar
• Suzuki Y. 2015. Influences of radiation on carp from farm ponds in Fukushima. J Radiat Res. 56:i19–i23.
   PubMed Web of Science ®Google Scholar
• Vo NTK, Bender AW, Lee LEJ, Lumsden JS, Lorenzen N, Dixon B, Bols NC. 2015a. Development of a walleye cell line and use to study the effects of temperature on infection by viral haemorrhagic septicaemia virus group IVb. J Fish Dis. 38:121–136.
   PubMed Web of Science ®Google Scholar
• Vo NTK, Bender AW, Lumsden JS, Dixon B, Bols NC. 2016. Differential viral haemorrhagic septicaemia virus genotype IVb infection in fin fibroblast and epithelial cell lines from walleye, Sander vitreus (Mitchill), at cold temperatures. J Fish Dis. 39:175–188.
   PubMed Web of Science ®Google Scholar
• Vo NTK, Bols NC. 2016. Demonstration of primary cilia and acetylated α-tubulin in fish endothelial, epithelial and fibroblast cell lines. Fish Physiol Biochem. 42:29–38.
   PubMed Web of Science ®Google Scholar
• Vo NTK, Mikhaeil MS, Lee LEJ, Pham PH, Bols NC. 2015b. Senescence-associated β-galactosidase staining in fish cell lines and primary cultures from several tissues and species, including rainbow trout coelomic fluid and milt. In Vitro Cell Dev Biol Anim. 51:361–371.
   PubMed Web of Science ®Google Scholar
• Vo NTK, Moore L, Spiteri KW, Hanner R, Wilkie M, DeWitte-Orr SJ. 2018. Assessing off-target cytotoxicity of the field lampricide 3-trifluoromethyl-4-nitrophenol using novel lake sturgeon cell lines. Ecotoxicol Environ Saf. 162:536–545.
   PubMed Web of Science ®Google Scholar
• Vo NTK, Seymour CB, Mothersill CE. 2017a. Dose rate effects of low-LET ionizing radiation on fish cells. Radiat Environ Biophys. 56:433–441.
   PubMed Web of Science ®Google Scholar
• Vo NTK, Seymour CB, Mothersill CE. 2019a. The common field lampricide 3-trifluoromethyl-4-nitrophenol is a potential radiosensitizer in fish cells. Environ Res. 170:383–388.
   PubMed Web of Science ®Google Scholar
• Vo NTK, Seymour CB, Mothersill CE. 2019b. Radiobiological characteristics of descendant progeny of fish and amphibian cells that survive the initial ionizing radiation dose. Environ Res. 169:494–500.
   PubMed Web of Science ®Google Scholar
• Vo NTK, Sokeechand BSH, Seymour CB, Mothersill CE. 2017b. Characterizing responses to gamma radiation by a highly clonogenic fish brain endothelial cell line. Environ Res. 156:297–305.
   PubMed Web of Science ®Google Scholar
• Whicker FW, Schultz V. 1982. Radioecology: nuclear energy and the environment. Boca Raton (FL): CRC Press.
   Google Scholar
• Wolf K, Quimby MC. 1962. Established eurythermic line of fish cells in vitro. Science. 135:1065–1066.
   PubMed Web of Science ®Google Scholar
• Xing JG, El-Sweisi W, Lee LE, Collodi P, Seymour C, Mothersill C, Bols NC. 2009. Development of a zebrafish spleen cell line, ZSSJ, and its growth arrest by gamma irradiation and capacity to act as feeder cells. In Vitro Cell Dev Biol Anim. 45:163–174.
   PubMed Web of Science ®Google Scholar
• Yew FH, Chang LM. 1984. DNA replication and repair in Tilapia cells. I. The effect of ultraviolet radiation. J Cell Sci. 72:213–226.
   PubMed Web of Science ®Google Scholar
• Zeng F, Yu X, Sherry JP, Dixon B, Duncker BP, Bols NC. 2016. The p53 inhibitor, pifithrin-α, disrupts microtubule organization, arrests growth, and induces polyploidy in the rainbow trout gill cell line, RTgill-W1. Comp Biochem Physiol C Toxicol Pharmacol. 179:1–10.
   PubMed Web of Science ®Google Scholar