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Original Articles

Muscle regeneration after high-dose radiation exposure: therapeutic potential of Hedgehog pathway modulation?

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Pages 968-979 | Received 08 Oct 2021, Accepted 29 Nov 2021, Published online: 17 Dec 2021

References

  • Anderson C, Williams VC, Moyon B, Daubas P, Tajbakhsh S, Buckingham ME, Shiroishi T, Hughes S, Borycki A-G. 2012. Sonic hedgehog acts cell-autonomously on muscle precursor cells to generate limb muscle diversity. Genes Dev. 26(18):2103–2117.
  • Appell HJ, Forsberg S, Hollmann W. 1988. Satellite cell activation in human skeletal muscle after training: evidence for muscle fiber neoformation. Int J Sports Med. 9(4):297–299.
  • Bajaj P, Reddy B, Millet L, Wei C, Zorlutuna P, Bao G, Bashir R. 2011. Patterning the differentiation of C2C12 skeletal myoblasts. Integr Biol (Camb). 3(9):897–909.
  • Berman DM, Karhadkar SS, Maitra A, Montes De Oca R, Gerstenblith MR, Briggs K, Parker AR, Shimada Y, Eshleman JR, Watkins DN, et al. 2003. Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours. Nature. 425(6960):846–851.
  • Bey E, Prat M, Duhamel P, Benderitter M, Brachet M, Trompier F, Battaglini P, Ernou I, Boutin L, Gourven M, et al. 2010. Emerging therapy for improving wound repair of severe radiation burns using local bone marrow-derived stem cell administrations. Wound Repair Regen. 18(1):50–58.
  • Blau HM, Chiu CP, Webster C. 1983. Cytoplasmic activation of human nuclear genes in stable heterocaryons. Integr Biol (Camb). 32(4):1171–1180.
  • Bonifas JM, Pennypacker S, Chuang PT, McMahon AP, Williams M, Rosenthal A, De Sauvage FJ, Epstein EH. 2001. Activation of expression of hedgehog target genes in basal cell carcinomas. J Invest Dermatol. 116(5):739–742.
  • Bürglin TR. 2008. The Hedgehog protein family. Genome Biol. 9(11):241.
  • Caiozzo VJ, Giedzinski E, Baker M, Suarez T, Izadi A, Lan M, Cho-Lim J, Tseng BP, Limoli CL. 2010. The radiosensitivity of satellite cells: cell cycle regulation, apoptosis and oxidative stress. Radiat Res. 174(5):582–589.
  • Caradu C, Guy A, James C, Reynaud A, Gadeau A-P, Renault M-A. 2018. Endogenous Sonic Hedgehog limits inflammation and angiogenesis in the ischaemic skeletal muscle of mice. Cardiovasc Res. 114(5):759–770.
  • Collins CA, Olsen I, Zammit PS, Heslop L, Petrie A, Partridge TA, Morgan JE. 2005. Stem cell function, self-renewal, and behavioral heterogeneity of cells from the adult muscle satellite cell niche. Cell. 122(2):289–301.
  • Elia D, Madhala D, Ardon E, Reshef R, Halevy O. 2007. Sonic hedgehog promotes proliferation and differentiation of adult muscle cells: involvement of MAPK/ERK and PI3K/Akt pathways. Biochim Biophys Acta. 1773(9):1438–1446.
  • Forcheron F, Agay D, Scherthan H, Riccobono D, Herodin F, Meineke V, Drouet M. 2012. Autologous adipocyte derived stem cells favour healing in a minipig model of cutaneous radiation syndrome. PLoS One. 7(2):e31694.
  • François S, Eder V, Belmokhtar K, Machet M-C, Douay L, Gorin N-C, Benderitter M, Chapel A. 2017. Synergistic effect of human bone morphogenic protein-2 and mesenchymal stromal cells on chronic wounds through hypoxia-inducible factor-1 α induction. Sci Rep. 7(1):4272.
  • François S, Mouiseddine M, Mathieu N, Semont A, Monti P, Dudoignon N, Saché A, Boutarfa A, Thierry D, Gourmelon P, et al. 2007. Human mesenchymal stem cells favour healing of the cutaneous radiation syndrome in a xenogenic transplant model. Ann Hematol. 86(1):1–8.
  • Giarretta I, Gaetani E, Bigossi M, Tondi P, Asahara T, Pola R. 2019. The Hedgehog signaling pathway in ischemic tissues. IJMS. 20(21):5270. https://doi.org/https://doi.org/10.3390/ijms20215270.
  • Hadden MK. 2014. Hedgehog pathway agonism: therapeutic potential and small-molecule development. ChemMedChem. 9(1):27–37.
  • Hahn H, Wojnowski L, Zimmer AM, Hall J, Miller G, Zimmer A. 1998. Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome. Nat Med. 4(5):619–622.
  • Harris RJC. 1963. Cellular basis and aetiology of late somatic effects of ionizing radiation. Cellular basis and aetiology of late somatic effects of ionizing radiation [Internet]. [accessed 2021 Oct 2]. https://www.cabdirect.org/cabdirect/abstract/19631605348.
  • Hawke TJ, Garry DJ. 2001. Myogenic satellite cells: physiology to molecular biology. J Appl Physiol (1985). 91(2):534–551.
  • Heretsch P, Tzagkaroulaki L, Giannis A. 2010. Cyclopamine and hedgehog signaling: chemistry, biology, medical perspectives. Angew Chem Int Ed Engl. 49(20):3418–3427.
  • Hoerth E, Kodym R. 2004. Involvment of c-Abl in the radiation-induced inhibition of myoblast differentiation. Int J Radiat Biol. 80(10):729–736.
  • Hopewell JW. 1990. The skin: its structure and response to ionizing radiation. Int J Radiat Biol. 57(4):751–773.
  • Hu JK-H, McGlinn E, Harfe BD, Kardon G, Tabin CJ. 2012. Autonomous and nonautonomous roles of Hedgehog signaling in regulating limb muscle formation. Genes Dev. 26(18):2088–2102.
  • Ikeda S, Hachisu R, Yamaguchi A, Gao YH, Okano T. 2000. Radiation retards muscle differentiation but does not affect osteoblastic differentiation induced by bone morphogenetic protein-2 in C2C12 myoblasts. Int J Radiat Biol. 76(3):403–411.
  • Jurdana M. 2008. Radiation effects on skeletal muscle. Radiol Oncol. 42(1):15–22. doi:https://doi.org/10.2478/v10019-007-0034-5.
  • Koleva M, Kappler R, Vogler M, Herwig A, Fulda S, Hahn H. 2005. Pleiotropic effects of sonic hedgehog on muscle satellite cells. Cell Mol Life Sci. 62(16):1863–1870.
  • Lataillade J-J, Bey E, Thepenier C, Prat M, Leclerc T, Bargues L. 2010. Skin engineering for burns treatment. Bull Acad Natl Med. 194(7):1339–1351.
  • Lataillade JJ, Doucet C, Bey E, Carsin H, Huet C, Clairand I, Bottollier-Depois JF, Chapel A, Ernou I, Gourven M, et al. 2007. New approach to radiation burn treatment by dosimetry-guided surgery combined with autologous mesenchymal stem cell therapy. Regen Med. 2(5):785–794.
  • Lefaix JL, Delanian S. 2005. Menace terroriste nucléaire: approche médicale. Arcueil, France: John Libbey Eurotext Plc; p. 87–95.
  • Linard C, Brachet M, L’homme B, Strup-Perrot C, Busson E, Bonneau M, Lataillade J-J, Bey E, Benderitter M. 2018. Long-term effectiveness of local BM-MSCs for skeletal muscle regeneration: a proof of concept obtained on a pig model of severe radiation burn. Stem Cell Res Ther. 9(1):299.
  • Mauro A. 1961. SATELLITE CELL OF SKELETAL MUSCLE FIBERS. J Biophys Biochem Cytol. 9(2):493–495.
  • McMahon DK, Anderson PA, Nassar R, Bunting JB, Saba Z, Oakeley AE, Malouf NN. 1994. C2C12 cells: biophysical, biochemical, and immunocytochemical properties. Am J Physiol. 266(6):C1795–C1802.
  • Piccioni A, Gaetani E, Palladino M, Gatto I, Smith RC, Neri V, Marcantoni M, Giarretta I, Silver M, Straino S, et al. 2014. Sonic hedgehog gene therapy increases the ability of the dystrophic skeletal muscle to regenerate after injury. Gene Ther. 21(4):413–421.
  • Renault M-A, Robbesyn F, Chapouly C, Yao Q, Vandierdonck S, Reynaud A, Belloc I, Traiffort E, Ruat M, Desgranges C, et al. 2013. Hedgehog-dependent regulation of angiogenesis and myogenesis is impaired in aged mice. Arterioscler Thromb Vasc Biol. 33(12):2858–2866.
  • Renault M-A, Vandierdonck S, Chapouly C, Yu Y, Qin G, Metras A, Couffinhal T, Losordo DW, Yao Q, Reynaud A, et al. 2013. Gli3 regulation of myogenesis is necessary for ischemia-induced angiogenesis. Circ Res. 113(10):1148–1158.
  • Reyes EH, Baciu F, Benderitter M, Lataillade JJ, Bey E, Trompier F, Tamarat R. 2016. Medical Response to Radiological Accidents in Latin America and International Assistance. Radiat Res. 185(4):359–365.
  • Riccobono D, Agay D, François S, Scherthan H, Drouet M, Forcheron F. 2016. Contribution of INTRAMUSCULAR autologous adipose tissue-derived stem cell injections to treat cutaneous radiation syndrome: preliminary results. Health Phys. 111(2):117–126.
  • Riccobono D, Nikovics K, François S, Favier A-L, Jullien N, Schrock G, Scherthan H, Drouet M. 2018. First insights into the M2 inflammatory response after adipose-tissue-derived stem cell injections in radiation-injured muscles. Health Phys. 115(1):37–48.
  • Sakurai T, Ueda T, Kawai M, Tobita H, Miyakoshi J. 2009. Protective effects of insulin-like growth factor-I on the decrease in myogenic differentiation by ionizing radiation. Int J Radiat Biol. 85(2):153–158.
  • Sanchez P, Hernández AM, Stecca B, Kahler AJ, DeGueme AM, Barrett A, Beyna M, Datta MW, Datta S, Ruiz I Altaba A. 2004. Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling. Proc Natl Acad Sci U S A. 101(34):12561–12566.
  • Straface G, Aprahamian T, Flex A, Gaetani E, Biscetti F, Smith RC, Pecorini G, Pola E, Angelini F, Stigliano E, et al. 2009. Sonic hedgehog regulates angiogenesis and myogenesis during post-natal skeletal muscle regeneration. J Cell Mol Med. 13(8B):2424–2435.
  • Teperino R, Aberger F, Esterbauer H, Riobo N, Pospisilik JA. 2014. Canonical and non-canonical Hedgehog signalling and the control of metabolism. Semin Cell Dev Biol. 33:81–92.
  • Voronova A, Coyne E, Al Madhoun A, Fair JV, Bosiljcic N, St-Louis C, Li G, Thurig S, Wallace VA, Wiper-Bergeron N, et al. 2013. Hedgehog signaling regulates MyoD expression and activity. J Biol Chem. 288(6):4389–4404.
  • Wu Y, Zhao RCH, Tredget EE. 2010. Concise review: bone marrow-derived stem/progenitor cells in cutaneous repair and regeneration. Stem Cells. 28(5):905–915.
  • Yao Q, Renault M-A, Chapouly C, Vandierdonck S, Belloc I, Jaspard-Vinassa B, Daniel-Lamazière J-M, Laffargue M, Merched A, Desgranges C, et al. 2014. Sonic hedgehog mediates a novel pathway of PDGF-BB-dependent vessel maturation. Blood. 123(15):2429–2437.
  • Zammit PS, Partridge TA, Yablonka-Reuveni Z. 2006. The skeletal muscle satellite cell: the stem cell that came in from the cold. J Histochem Cytochem. 54(11):1177–1191.