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Original Articles

Ferulic acid produces neuroprotection against radiation-induced neuroinflammation by affecting NLRP3 inflammasome activation

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Pages 1442-1451 | Received 20 Apr 2021, Accepted 05 Mar 2022, Published online: 21 Apr 2022

References

  • Abderrazak A, Syrovets T, Couchie D, El Hadri K, Friguet B, Simmet T, Rouis M. 2015. NLRP3 inflammasome: from a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases. Redox Biol. 4:296–307.
  • Alcocer-Gómez E, Castejón-Vega B, Cordero M. 2017. Stress-induced NLRP3 inflammasome in human diseases. Adv Protein Chem Struct Biol. 108:127–162.
  • Battleday R, Brem A. 2016. Modafinil for cognitive neuroenhancement in healthy non-sleep-deprived subjects: a systematic review. Eur Neuropsychopharmacol. 26(2):391.
  • Brown P, Ahluwalia M, Khan O, Asher A, Wefel J, Gondi V. 2018. Whole-brain radiotherapy for brain metastases: evolution or revolution? J Clin Oncol. 36(5):483–491.
  • Buthut M, Haussmann R, Seidlitz A, Krause M, Donix M. 2018. [Cognitive deficits following brain tumor radiation therapy]. Nervenarzt. 89(4):423–430.
  • Cascella M, Di Napoli R, Carbone D, Cuomo G, Bimonte S, Muzio M. 2018. Chemotherapy-related cognitive impairment: mechanisms, clinical features and research perspectives. Recenti Prog Med. 109(11):523–530.
  • Chaudhary A, Jaswal V, Choudhary S, Sonika Sharma A, Beniwal V, Tuli H, Sharma S. 2019. Ferulic acid: a promising therapeutic phytochemical and recent patents advances. Recent Pat Inflamm Allergy Drug Discov. 13(2):115–123.
  • Chen N, Yang M, Zhou M, Xiao J, Guo J, He L. 2017. L-carnitine for cognitive enhancement in people without cognitive impairment. Cochrane Database Syst Rev. 3:CD009374.
  • Fan H, Tang H, Chen Z, Wang H, Zhang L, Jiang Y, Li T, Yang C, Wang X, Li X, et al. 2020. Inhibiting HMGB1-RAGE axis prevents pro-inflammatory macrophages/microglia polarization and affords neuroprotection after spinal cord injury. J Neuroinflammation. 17(1):295.
  • Gugliandolo A, Giacoppo S, Bramanti P, Mazzon E. 2018. NLRP3 inflammasome activation in a transgenic amyotrophic lateral sclerosis model. Inflammation. 41(1):93–103.
  • Helson L. 2018. Radiation-induced demyelination and remyelination in the central nervous system: a literature review. Anticancer Res. 38(9):4999–5002.
  • Heneka M, Kummer M, Stutz A, Delekate A, Schwartz S, Vieira-Saecker A, Griep A, Axt D, Remus A, Tzeng T, et al. 2013. NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice. Nature. 493(7434):674–678.
  • Hickman S, Izzy S, Sen P, Morsett L, El Khoury J. 2018. Microglia in neurodegeneration. Nat Neurosci. 21(10):1359–1369.
  • Huang H, Hong Q, Tan H, Xiao C, Gao Y. 2016. Ferulic acid prevents LPS-induced up-regulation of PDE4B and stimulates the cAMP/CREB signaling pathway in PC12 cells. Acta Pharmacol Sin. 37(12):1543–1554.
  • Labzin L, Heneka M, Latz E. 2018. Innate immunity and neurodegeneration. Annu Rev Med. 69:437–449.
  • Liu Y, Chen J, Zhang Z, Ma X, Chen Y, Du X, Liu H, Zong Y, Lu G. 2017. NLRP3 inflammasome activation mediates radiation-induced pyroptosis in bone marrow-derived macrophages. Cell Death Dis. 8(2):e2579.
  • Liu Y, Zhang X, Yan D, Wang Y, Wang N, Liu Y, Tan A, Chen X, Yan H. 2020. Chronic acrylamide exposure induced glia cell activation, NLRP3 infl-ammasome upregulation and cognitive impairment. Toxicol Appl Pharmacol. 393:114949.
  • Ma Z, Gao Y, Tan H, Liang Q, Wang S. 2005. Study of blood-tonifying mechanisms of Siwutang of Traditional Chinese Medicine by technology of TCM moleculomics. World Sci Technol. 7(3):24–28 + 85–86.
  • Ma Z, Hong Q, Wang Y, Tan H, Xiao C, Liang Q, Lu B, Gao Y. 2011. Effects of ferulic acid on hematopoietic cell recovery in whole-body gamma irradiated mice. Int J Radiat Biol. 87(5):499–505.
  • Ma Z, Hong Q, Wang Y, Tan H, Xiao C, Liang Q, Wang D, Gao Y. 2011. Ferulic acid protects lymphocytes from radiation-predisposed oxidative stress through extracellular regulated kinase. Int J Radiat Biol. 87(2):130–140.
  • Niu L, Luo S, Xu Y, Wang Z, Luo D, Yang H, Li W, He J, Zhong X, Liu Z, et al. 2020. The critical role of the hippocampal NLRP3 inflammasome in social isolation-induced cognitive impairment in male mice. Neurobiol Learn Mem. 175:107301.
  • O'Brien W, Pham L, Symons G, Monif M, Shultz S, McDonald S. 2020. The NLRP3 inflammasome in traumatic brain injury: potential as a biomarker and therapeutic target. J Neuroinflammation. 17(1):104.
  • Ownby R. 2010. Neuroinflammation and cognitive aging. Curr Psychiatry Rep. 12(1):39–45.
  • Parihar V, Allen B, Caressi C, Kwok S, Chu E, Tran K, Chmielewski N, Giedzinski E, Acharya M, Britten R, et al. 2016. Cosmic radiation exposure and persistent cognitive dysfunction. Sci Rep. 6:34774.
  • Passamonti L, Tsvetanov K, Jones P, Bevan-Jones W, Arnold R, Borchert R, Mak E, Su L, O'Brien J, Rowe J. 2019. Neuroinflammation and functional connectivity in Alzheimer's disease: interactive influences on cognitive performance. J Neurosci. 39(36):7218–7226.
  • Piirainen S, Youssef A, Song C, Kalueff A, Landreth G, Malm T, Tian L. 2017. Psychosocial stress on neuroinflammation and cognitive dysfunctions in Alzheimer's disease: the emerging role for microglia? Neurosci Biobehav Rev. 77:148–164.
  • Rehman S, Ali T, Alam S, Ullah R, Zeb A, Lee K, Rutten B, Kim M. 2019. Ferulic acid rescues LPS-induced neurotoxicity via modulation of the TLR4 receptor in the mouse hippocampus. Mol Neurobiol. 56(4):2774–2790.
  • Salau V, Erukainure O, Ibeji C, Olasehinde T, Koorbanally N, Islam M. 2020. Ferulic acid modulates dysfunctional metabolic pathways and purinergic activities, while stalling redox imbalance and cholinergic activities in oxidative brain injury. Neurotox Res. 37(4):944–955.
  • Shao S, Gao Y, Liu J, Tian M, Gou Q, Su X. 2018. Ferulic acid mitigates radiation injury in human umbilical vein endothelial cells in vitro via the thrombomodulin pathway. Radiat Res. 190(3):298–308.
  • Shin D, Lee G, Sohn S, Park S, Jung K, Lee J, Yang J, Cho J, Bae H. 2016. Regulatory T cells contribute to the inhibition of radiation-induced acute lung inflammation via Bee Venom phospholipase A2 in mice. Toxins. 8(5):131.
  • Sohn S, Lee J, Park S, Yoo H, Kang J, Shin D, Jung K, Lee Y, Cho J, Bae H. 2015. The inflammasome accelerates radiation-induced lung inflammation and fibrosis in mice. Environ Toxicol Pharmacol. 39(2):917–926.
  • Sui DM, Xie Q, Yi WJ, Gupta S, Yu XY, Li JB, Wang J, Wang JF, Deng XM. 2016. Resveratrol protects against sepsis-Associated encephalopathy and inhibits the NLRP3/IL-1β axis in microglia. Mediators Inflamm. 2016:1045657.
  • Tricco A, Ashoor H, Soobiah C, Rios P, Veroniki A, Hamid J, Ivory J, Khan P, Yazdi F, Ghassemi M, et al. 2018. Comparative effectiveness and safety of cognitive enhancers for treating Alzheimer's disease: systematic review and network metaanalysis. J Am Geriatr Soc. 66(1):170–178.
  • Tsai F, Wu L, Yang S, Cheng H, Tsai C, Wu C, Lin L. 2015. Ferulic acid reverses the cognitive dysfunction caused by amyloid β peptide 1-40 through anti-oxidant activity and cholinergic activation in rats. Am J Chin Med. 43(2):319–335.
  • Turnquist C, Harris B, Harris C. 2020. Radiation-induced brain injury: current concepts and therapeutic strategies targeting neuroinflammation. Neurooncol Adv. 2(1):vdaa057.
  • Wang H, Sun X, Zhang N, Ji Z, Ma Z, Fu Q, Qu R, Ma S. 2017. Ferulic acid attenuates diabetes-induced cognitive impairment in rats via regulation of PTP1B and insulin signaling pathway. Physiol Behav. 182:93–100.
  • Ward R, Li W, Abdul Y, Jackson L, Dong G, Jamil S, Filosa J, Fagan S, Ergul A. 2019. NLRP3 inflammasome inhibition with MCC950 improves diabetes-mediated cognitive impairment and vasoneuronal remodeling after ischemia. Pharmacol Res. 142:237–250.
  • Wei J, Wang H, Wang H, Wang B, Meng L, Xin Y, Jiang X. 2019. The role of NLRP3 inflammasome activation in radiation damage. Biomed Pharmacother. 118:109217.
  • Wei P, Yang F, Zheng Q, Tang W, Li J. 2019. The potential role of the NLRP3 inflammasome activation as a link between mitochondria ROS generation and neuroinflammation in postoperative cognitive dysfunction. Front Cell Neurosci. 13:73.
  • Wu K, Wang Z, Liu D, Qi X. 2014. Pharmacokinetics, brain distribution, release and blood-brain barrier transport of Shunaoxin pills. J Ethnopharmacol. 151(3):1133–1140.
  • Yang H, Qu Z, Zhang J, Huo L, Gao J, Gao W. 2016. Ferulic acid ameliorates memory impairment in d-galactose-induced aging mouse model. Int J Food Sci Nutr. 67(7):806–817.

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