13
Views
22
CrossRef citations to date
0
Altmetric
Original Article

Cell Inactivation and DNA Single- and Double-strand Breaks in Cultured Mammalian Cells Irradiated by a Thermal Neutron Beam

, , , &
Pages 795-809 | Received 23 Jan 1986, Accepted 03 Apr 1986, Published online: 03 Jul 2009

References

  • Ahnström G., Edvardsson K.A. Radiation-induced single-strand breaks in DNA determined by rate of alkaline strand separation and hydroxylapatite chromatography: an alternative to velocity sedimentation. International Journal of Radiation Biology 1974; 26: 493–497
  • Altman P.L., Ditter D.S. Biology Data Book Isecond edition. Federation of American Societies for Experimental Biology. 1972; 392–392
  • Ban S., Ikushima F., Sugahara T. Reduction in proliferative life span of human diploid cells after exposure to a reactor radiation beam. Radiation Research 1981; 87: 1–9
  • Bauchinger M., Schmid E., Rimpl G., Kühn H. Chromosome aberrations in human lymphocytes after irradiation with 15·0-MeV neutrons in vitro 1. Dose-response relation on RBE. Mutation Research 1975; 27: 103–109
  • Bradley M.O., Kohn K.W. X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution. Nucleic Acid Research 1979; 7: 793–804
  • Bryant P.E., Blöcher D. Measurement of the kinetics of DNA double strand break repair in Ehrlich ascites tumour cells using the unwinding method. International Journal of Radiation Biology 1980; 38: 335–347
  • Christensen R.C., Tobias C.A., Taylor W.D. Heavy-ion-induced single-and double-strand breaks in φ-174 replicative form DNA. International Journal of Radiation Biology 1972; 22: 457–477
  • Deering R.A., Rice R. Heavy ion irradiation of HeLa cells. Radiation Research 1962; 17: 774–786
  • Elkind M.M. Damage and repair processes relative to neutron and charged particle irradiation. Current Topics in Radiation Research Quarterly 1970; 7: 17–21
  • Elkind M.M. The initial part of the survival curve. Implications for low-dose, low-dose-rate radiation response. Radiation Research 1977; 71: 9–23
  • Furuno I., Yada T., Matsudaira H., Maruyama T. Induction and repair of DNA strand breaks in cultured mammalian cells following fast neutron irradiation. International Journal of Radiation Biology 1979; 36: 639–648
  • Hall E.J., Novak J.K., Kellerer A.M., Rossi H.H., Marino S., Goodman L.J. RBE as a function of neutron energy 1. Experimental observations. Radiation Research 1975; 64: 245–255
  • Hesselwood I.P. DNA strand breaks in resistant and sensitive lymphoma cells detected by the hydroxyapatite chromatographic technique. International Journal of Radiation Biology 1978; 34: 461–469
  • Jung H., Zimmer K.G. Current Topics in Radiation Research Vol. II, M. Ebert, A. Howard. North-Holland, Amsterdam 1966; 69–69
  • Kampf G., Tolkendorft E., Regel K., Abel H. Cell inactivation and DNA strand break rates after irradiation with X-rays and fast neutrons. Studia Biophysica 1977; 62: 17–24
  • Kellerer A.M., Hall E.J., Rossi H.H., Teedla P. RBE as a function of neutron energy II. Statistical analysis. Radiation Research 1976; 65: 172–186
  • Kobayashi T., Kanda K. Analytical calculation of Boron-10 dosage in cell nucleus for neutron capture therapy. Radiation Research 1982; 91: 77–94
  • Kohn K.W., Erickson L.C., Ewig R.A.G., Friedman C.A. Fractionation of DNA from mammalian cells by alkaline elution. Biochemistry 1976; 15: 4629–4637
  • Körner I.J., Günther K., Malz W. Kinetics of DNA single-strand break rejoining in X- and neutron-irradiated Chinese hamster cells. Studia Biophysica 1978; 70: 175–182
  • McNally N.J., Ronde J.D., Hinchliffe M. The effect of sequential irradiation with X-rays and fast neutrons on the survival of V79 Chinese hamster cells. International Journal of Radiation Biology 1984; 45: 301–310
  • McNally N.J., Ronde J.D., Hinchliffe M. Survival of V79 cells following simultaneous irradiation with X-rays and neutrons in air or hypoxia. International Journal of Radiation Biology 1985; 48: 847–855
  • McWilliams R.S., Cross W.G., Kaplan J.G., Birnboim H.C. Rapid rejoining of DNA strand breaks in resting human lymphocytes after irradiation by low doses of 60Co γ-rays of 14·6-MeV neutrons. Radiation Research 1983; 94: 499–507
  • Maki H., Saito M., Kawai K., Honda Y., Akaboshi M. The contribution of the nuclear reaction 1H(n,γ)2D to the yield of DNA single strand breaks in cultured mammalian cells irradiated by thermal neutrons. International Journal of Radiation Biology 1985; 48: 545–554
  • Moss A.J., Baker M.L., Prior R.M., Erichsen E.A., Nagle W.A., Dalrymple G.V. Fast neutron and X-ray induced single strand DNA breaks in cultured mammalian cells. Radiology 1976; 119: 459–461
  • Nakanishi T., Ichihashi M., Mishima Y., Matsuzawa T., Fukuda H. Thermal neutron capture therapy of malignant melanoma: in vitro radiological analysis. International Journal of Radiation Biology 1980; 37: 573–580
  • Ngo F.Q.H., Blakely E.A., Tobias C.A. Sequential exposures of mammalian cells to low- and high-LET radiations 1. Lethal effects following X-ray and Neon-ion irradiation. Radiation Research 1981; 87: 59–78
  • Railton R., Lawson R.C., Porter D. Interaction of γ-ray and neutron effects on the proliferative capacity of Chinese hamster cells. International Journal of Radiation Biology 1975; 27: 75–82
  • Ritter M., Cleaver J.E., Tobias C.A. High-LET radiations induce a large production of non-rejoining DNA breaks. Nature 1977; 266: 653–655
  • Sakai K., Okada S. Radiation-induced DNA damage and cellular lethality in cultured mammalian cells. Radiation Research 1980; 98: 479–490
  • Ujeno Y., Takimoto K. Deuterium isotope effect on radiation damages to mammalian cells. Annual Reports of the Research Reactor Institute Kyoto University 1980; 13: 62–66
  • Utsumi H., Hill C.K., Ben-Hur E., Elkind M.M. Single-hit potentially lethal damage: Evidence of its repair in mammalian cells. Radiation Research 1981; 87: 576–591
  • Van Der Schans G.P., Paterson M.C., Cross W.G. DNA strand break and rejoining in cultured human fibroblasts exposed to fast neutrons or gamma rays. International Journal of Radiation Biology 1983; 44: 75–85
  • Weibezahn K.F., Coquerelle T. Radiation induced DNA double strand breaks are rejoined by ligation and recombination processes. Nucleic Acid Research 1981; 9: 3139–3150

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.