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Original Article

Nuclear Glutathione and Oxygen Enhancement of Radiosensitivity

Pages 3-6 | Received 14 Jul 1986, Accepted 08 Sep 1986, Published online: 03 Jul 2009

References

  • Alper T., Howard-Flanders P. Role of oxygen in modifying the radiosensitivity of E. coli B. Nature 1956; 178: 978–979
  • Edgren M., Nishidai T., Scott O.C.A., Révész L. Combined effect of misonidazole and glutathione depletion by buthionine sulphoximine on cellular radiation response. International Journal of Radiation Biology 1985; 47: 463–474
  • Edgren M.R., Sölen G., Révész L. Specificity of endogenous glutathione in determining the oxygen enhancement of cellular radiosensitivity. International Journal of Radiation Oncology, Biology, Physics 1986; 12: 1147–1150
  • Griffith O.W. Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine. Analytical Biochemistry 1980; 106: 207–212
  • Griffith O.W., Meister A. Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine. Journal of Biological Chemistry 1979; 254: 7558–7560
  • Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with folin phenol reagent. Journal of Biological Chemistry 1951; 193: 265–275
  • Nüsse M., Kramer J. Flow cytometric analysis of micronuclei found in cells after irradiation. Cytometry 1984; 5: 20–25
  • Révész L. The role of endogenous thiols in intrinsic radio-protection. Review. International Journal of Radiation Biology 1985; 47: 361–368
  • Tietze F. Enzymatic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues. Analytical Biochemistry 1969; 27: 502–522

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