Cellular Responses to Ionizing Radiation: Effects of Interrupting DNA Repair with Chemical Agents

References

• Ahnström G., Bryant P.E. DNA double-strand breaks generated by the repair of X-ray damage in Chinese hamster cells. International Journal of Radiation Biology 1982; 4: 671–676
   Google Scholar
• Bender M.A., Preston R.J. Role of base damage in aberration formation: interaction of aphidicolin and X-rays. Progress in Mutation Research 1982; 4: 37–46
   Google Scholar
• Ben-Hur E. Enhanced radiation-induced killing of Chinese hamster cells by dideoxythymidine. Radiation Research 1981; 88: 155–164
   PubMed Web of Science ®Google Scholar
• Ben-Hur E. Involvement of poly(ADP-ribose) in the radiation response of mammalian cells. International Journal of Radiation Biology 1984; 46: 659–671
   Web of Science ®Google Scholar
• Ben-Hur E., Elkind M.M. Poly(ADP-ribose) metabolism in X-irradiated Chinese hamster cells: its relation to repair of potentially lethal damage. International Journal of Radiation Biology 1984; 45: 515–523
   Google Scholar
• Berry J.R., Evans H.J., Robinson D.M. Perturbations in X-ray dose response in vitro with time after plating; a pitfall in the comparison of results obtained by different laboratories using asynchronous cell systems. Experimental Cell Research 1966; 42: 512–522
   PubMed Web of Science ®Google Scholar
• Bryant P.E. Effects of ara A and fresh medium on chromosome damage and DNA double-strand break repair in X-irradiated stationary cells. British Journal of Cancer 1984; 49(VI)61–65
   Google Scholar
• Bryant P.E., Blöcher D. The effects of 9-β-d-arabinofuranosyladenine on the repair of DNA strand breaks in X-irradiated Ehrlich ascites tumour cells. International Journal of Radiation Biology 1982; 42: 385–394
   Web of Science ®Google Scholar
• Bryant P.E., Iliakis G. Possible correlations between cell killing, chromosome damage and DNA repair after X-irradiation. DNA Repair and its Inhibition, A. Collins, C.S. Downes, R.T. Johnson. IRL Press, Oxford 1984; 291–308
   Google Scholar
• Cleaver J.E., Park S.D. Enhanced ligation of repair sites under conditions of inhibition of poly(ADP-ribose) synthesis by 3-aminobenzamide. Mutation Research 1986; 173: 287–290
   Google Scholar
• Collins A.R.S. DNA synthesis in mammalian cells: its integration within the cell cycle. University of Cambridge. 1972, PhD thesis
   Google Scholar
• Collins A.R.S. DNA damage in ultraviolet-irradiated HeLa and CHO-K1 cells examined by alkaline lysis and hydroxyapatite chromatography. Biochimica et Biophysica Acta 1977; 478: 461–473
   PubMedGoogle Scholar
• Collins A. Poly(ADP-ribose) is not involved in the rejoining of DNA breaks accumulated to high levels in u.v.-irradiated HeLa cells. Carcinogenesis 1985; 6: 1033–1036
   Google Scholar
• Collins A., Johnson R.T. Novobiocin; an inhibitor of the repair of u.v.-induced but not X-ray-induced damage in mammalian cells. Nucleic Acids Research 1979; 7: 1311–1320
   PubMed Web of Science ®Google Scholar
• Collins A.R.S., Squires S., Johnson R.T. Inhibitors of repair DNA synthesis. Nucleic Acids Research 1982; 10: 1203–1213
   PubMed Web of Science ®Google Scholar
• Debenham P.G., Webb M.B.T., Jones N.J., Cox R. Molecular studies on the nature of the repair defect in ataxia-telangiectasia and their implications for cellular radiobiology. Molecular Biology of DNA Reapir, A. Collins, R.T. Johnson, J.M. Boyle. Company of Biologists, Cambridge 1987; 177–189
   Google Scholar
• Downes C.S., Ord M.J., Mullinger A.M., Collins A.R.S., Johnson R.T. Novobiocin inhibition of DNA excision repair may occur through effects on mitochondrial structure and ATP metabolism, not on repair topoisomerases. Carcinogenesis 1985; 6: 1343–1352
   PubMed Web of Science ®Google Scholar
• Filatov M.V., Noskin L.A. Sensitization of human cells by inhibitors of DNA synthesis following the action of DNA-damaging agents. Mutation Research 1983; 110: 393–399
   Google Scholar
• George A.M., Lunec J., Cramp W.A., Brennan S., Lewis P.D., Whish W.J.D. The effects of benzamide ADP-ribosyl transferase inhibitros on cell survival and DNA strand-break repair in irradiated mammalian cells. International Journal of Radiation Biology 1986; 49: 783–798
   Web of Science ®Google Scholar
• Held K.D., Bren G.D. Effects of oxygen and dithiothreitol on radiation induced DNA damage in cells. Abstracts; Mechanisms of DNA Damage and Repair. National Bureau of Standards, GaithersburgU.S.A. 1985
   Google Scholar
• Henner W.D., Grunberg S.M., Haseltine W.A. Sites and structure of γ-radiation-induced DNA strand breaks. Journal of Biological Chemistry 1982; 257: 11750–11754
   PubMed Web of Science ®Google Scholar
• Hiss E.A., Preston R.J. The effect of cytosine arabinoside on the frequency of single-strand breaks in DNA of mammalian cells following irradiation or chemical treatment. Biochimica et Biophysica Acta 1977; 478: 1–8
   PubMed Web of Science ®Google Scholar
• Iliakis G., Nüsse M. Aphidicolin promotes repair of potentially lethal damage in irradiated mammalian cells synchronised in S-phase. Biochemical and Biophysical Research Communications 1982; 104: 1209–1214
   Google Scholar
• Iliakis G., Nüsse M., Bryant P. Effects of aphidicolin on cell proliferation, repair of potentially lethal damage and repair of DNA strand breaks in Ehrlich ascites tumour cells. International Journal of Radiation Biology 1982; 42: 417–434
   Web of Science ®Google Scholar
• Jain V.K., Kalia V.K., Sharma R., Maharajan V., Menon M. Effects of 2-deoxy-d-glucose on glycolysis, proliferation kinetics and radiation response of human cancer cells. International Journal of Radiation Oncology, Biology, Physics 1985; 11: 943–950
   PubMed Web of Science ®Google Scholar
• James M.R., Lehmann A.R. Role of poly(adenosine diphosphate ribose) in deoxyribonucleic acid repair in human fibroblasts. Biochemistry 1982; 21: 4007–4013
   PubMed Web of Science ®Google Scholar
• Johnson R.T., Collins A.R.S., Waldren C.A. Prematurely condensed chromosomes and the analysis of DNA and chromosome lesions. Premature Chromosome Condensation, P.N. Rao, R.T. Johnson, K. Sperling. Academic Press, New York, London 1982; 253–308
   Google Scholar
• Keyse S.M., Tyrrell R.M. Evidence that novobiocin and nalidixic acid do not inhibit excision repair in u.v.-irradiated human skin fibroblasts at a pre-incision step. Carcinogenesis 1985; 6: 1231–1233
   PubMedGoogle Scholar
• Kihlman B.A., Andersson H.C. Synergistic enhancement of the frequency of chromatid aberrations in cultured human lymphocytes by combinations of inhibitors of DNA repair. Mutation Research 1985; 150: 313–325
   PubMedGoogle Scholar
• Kihlman B.A., Hartley B. Hydroxyurea: effect on Vicia chromosomes previously exposed to X-rays or to radiomimetic chemicals. Experimental Cell Research 1967; 48: 629–634
   PubMedGoogle Scholar
• Kihlman B.A., Natarajan A.T. Potentiation of chromosomal alterations by inhibitors of DNA repair. DNA Repair and its Inhibition, A. Collins, C.S. Downes, R.T. Johnson. IRL Press, Oxford 1984; 319–339
   Google Scholar
• Little J.B., Weichselbaum R.R., Dahlberg W.K., Ueno A.M., Brown D.M. Abstracts: Radiation Research Society. Differential response of human and rodent cell lines to chemical inhibition of X-ray induced PLD repair. 34th Annual Meeting, Las Vegas, 1986
   Google Scholar
• Lunec J., Sun G.-Q., George A.M., Whish W.J.D., Cramp W.A. Post-irradiation inhibition of scheduled DNA synthesis and stimulation of ADP-ribosylation in sensitive and resistant L5178Y murine lymphoma cells. International Journal of Radiation Biology 1983; 44: 645–651
   Web of Science ®Google Scholar
• Mattern M.R., Scudiero D.A. Dependence of mammalian DNA synthesis on DNA supercoiling, III. Characterization of the inhibition of replicative and repair type DNA synthesis by novobiocin and nalidixic acid. Biochimica et Biophysica Acta 1981; 653: 248–258
   PubMed Web of Science ®Google Scholar
• Painter R.B. Effect of caffeine on DNA synthesis in irradiated and unirradiated mammalian cells. Journal of Molecular Biology 1980; 143: 289–301
   PubMed Web of Science ®Google Scholar
• Preston R.J. The effect of cytosine arabinoside on the frequency of X-ray-induced chromosome aberrations in normal human leukocytes. Mutation Research 1980; 69: 71–79
   PubMed Web of Science ®Google Scholar
• Preston R.J. DNA repair and chromosome aberrations: interactive effects of radiation and chemicals. Progress in Mutation Research 1982; 4: 25–35
   Google Scholar
• Seki S., Ohashi M., Ogura H., Oda T. Possible involvement of DNA polymerases α and β in bleomycin-induced unscheduled DNA synthesis in permeable HeLa cells. Biochemical and Biophysical Research Communications 1982; 104: 1502–1508
   Google Scholar
• Shall S. ADP-ribose in DNA repair: a new component of DNA excision repair. Advances in Radiation Biology 1984; 11: 1–69
   Google Scholar
• Smith P.J., Anderson C.O., Watson J.V. Abnormal responses of ataxiatelangiectasia cells to a topoisomerase II-interactive drug (epipodophyllotoxin). British Journal of Cancer 1986; 54: 354–354
   Google Scholar
• Taylor J.H., Haut W.F., Tung J. Effects of fluorodeoxyuridine on DNA replication, chromosome breakage, and reunion. Proceedings of the National Academy of Sciences, U.S.A. 1962; 48: 190–198
   PubMedGoogle Scholar
• Utsumi H., Bahari I., Elkind M.M. Abstracts: Radiation Research Society. Sublethal and potentially lethal damage: additional evidence for independent repair processes. 34th Annual Meeting, Las Vegas, 1986
   Google Scholar