61
Views
209
CrossRef citations to date
0
Altmetric
Original Article

Human Lymphocytes Exposed to Low Doses of Ionizing Radiations Become Refractory to High Doses of Radiation as Well as to Chemical Mutagens that Induce Double-strand Breaks in DNA

, , , &
Pages 39-48 | Published online: 03 Jul 2009

References

  • Bender M.A., Griggs H.G., Bedford J.S. Mechanisms of chromosomal aberration production. III. Chemicals and ionizing radiation. Mutation Research 1974; 23: 197–212
  • Bodycote J., Wolff S. Metabolic breakdown of [3H]thymidine and the inability to measure human lymphocyte proliferation by incorporation of radioactivity. Proceedings of the National Academy of Sciences, U.S.A. 1986; 83: 4749–4753
  • Demple B., Halbrook J. Inducible repair of oxidative DNA damage in Escherichia coli. Nature 1983; 304: 466–468
  • Evans H.J. Molecular mechanisms in the induction of chromosome aberrations. Progress in Genetic Toxicology, D. Scott, B.A. Bridges, F.H. Sobels. Elsevier/North-Holland, Amsterdam 1977; 57–74
  • Heindorff K., Michaelis A., Aurich O., Rieger R. Peroxide pretreatment of Vicia faba root-tip meristems results in ‘clastogenic adaptation’ to maleic hydrazide but not to TEM. Mutation Research 1985; 142: 23–27
  • Howard A., Cowie F.G. Induced resistance in a desmid Closterium moniliferum. Radiation Research 1976; 65: 540–549
  • Lloyd R.S., Haidle C.W., Robberson D.L., Dodson M.L., Jr. A physical map of bleomycin-specific fragmentation sites on PM2 bacteriophage DNA. Current Microbiology 1978; 1: 45–50
  • Natarajan A.T., Obe G., van Zeeland A.A., Palitti F., Meijers M., Verdegaal-Immerzeel E.A.M. Molecular mechanisms involved in the production of chromosomal aberrations. II. Utilization of Neurospora endonuclease for the study of aberration production by X-rays in G1 and G2 stages of the cell cycle. Mutation Research 1980; 69: 293–305
  • Olivieri G., Bodycote J., Wolff S. Adaptive response of human lymphocytes to low concentrations of radioactive thymidine. Science 1984; 223: 594–597
  • Povirk L.F., Wübker W., Köhnlein W., Hutchinson F. DNA double-strand breaks and alkali-labile bonds produced by bleomycin. Nucleic Acids Research 1977; 4: 3573–3580
  • Rieger R., Michaelis A., Nicoloff H. Inducible repair processes in plant root tip meristems? ‘Below-additivity effects’ of unequally fractionated clastogen concentrations. Biologisches Zentralblatt 1982; 101: 125–138
  • Rieger R., Michaelis A., Takehisa S. ‘Clastogenic cross-adaptation’ is dependent on the clastogens used for induction of chromatid aberrations in Vicia faba root-tip meristems. Mutation Research 1985; 144: 171–175
  • Samson L., Cairns J. A new pathway for DNA repair in Escherichia coli. Nature 1977; 267: 281–283
  • Samson L., Schwartz J.L. Evidence for an adaptive DNA repair pathway in CHO and human skin fibroblast cell lines. Nature 1980; 287: 861–863
  • Samson L., Schwartz J.L. The induction of resistance to alkylating damage in mammalian cells. Induced Mutagenesis: Molecular Mechanisms and their Implications for Environmental Protection, C.W. Lawrence. Plenum, New York 1983; 291–309
  • Schubert I., Rieger R., Michaelis A. Effects of ‘G2-repair’ inhibitors on ‘clastogenic adaptation’ in Vicia faba. Molecular and General Genetics 1986; 204: 174–179
  • Shadley J., Wolff S. Very low doses of X-rays can cause human lymphocytes to become less susceptible to ionizing radiation. Mutagenesis 1987; 2: 95–96
  • Sobels F.H. Organic peroxides and mutagenic effects in Drosophila. Nature 1956; 177: 979–980
  • Sybenga J., Kleijer G. ‘Below-additivity’ and ‘protective effects’ of dose fractionation in Crotalaria intermedia. Mutation Research 1976; 34: 131–140
  • Tomasz M., Mercado C.M., Olson J., Chatterjie N. The mode of interaction of mitomycin C with deoxyribonucleic acid and other polynucleotides in vitro. Biochemistry 1974; 13: 4878–4887
  • Wiencke J.K., Afzal V., Olivieri G., Wolff S. Evidence that the [3H]thymidine-induced adaptive response of human lymphocytes to subsequent doses of X-rays involves the induction of a chromosomal repair mechanism. Mutagenesis 1986; 1: 375–380
  • Wolff S. Genetic effects and radiation-induced cell death. Frontiers of Radiation Therapy and Oncology, J.M. Vaeth. S. Karger, Basel 1972; 6: 459–469
  • Wolff S. Relation between DNA repair, chromosome aberrations, and sister chromatid exchanges. DNA Repair Mechanisms, P.C. Hanawalt, E.C. Friedberg, C.F. Fox. Academic Press, New York 1978; 751–760

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.