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Original Article

Transformation and Mutagenic Potential of Porphyrin Photodynamic Therapy in Mammalian Cells

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Pages 651-660 | Received 04 Sep 1987, Accepted 16 Nov 1987, Published online: 03 Jul 2009

References

  • Ames B.N. Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases. Science 1983; 221: 1256–1264
  • Ananthaswami H.N. Neoplastic transformation of C3H mouse embryo 10T 1/2 cells by 8-methoxypsoralen plus UVA radiation. Journal of Investigative Dermatology 1985; 85(2)102–106
  • Benedict W.F., Banerjee A., Gardner A., Jones P.A. Induction of morphological transformation in mouse C3H/10T 1/2 clone 8 cells and chromosomal damage in hamster cells by cancer chemotherapeutic agents. Cancer Research 1977; 37: 2202–2208
  • Ben-Hur E., Fujihara T., Suzuki F., Elkind M.M. Genetic toxicology of the photosensitization of Chinese hamster cells by phthalocyanines. Photochemistry and Photobiology 1987; 45: 227–230
  • Blazek E.R.N., Hariharan T.V. Alkaline elusion studies of hematoporphyrin derivative photosensitized DNA damage and repair in Chinese hamster ovary cells. Photochemistry and Photobiology 1984; 40: 5–13
  • Bradley M.O., Erickson L.C. Comparison of the effects of hydrogen peroxide and X-ray irradiation on toxicity, mutation and DNA damage/repair in mammalian cells (V-79). Biochimica et Biophysica Acta 1981; 654: 135–141
  • Buettner G.R., Need M.J. Hydrogen peroxide and hydroxyl free radical production by hematoporphyrin derivative, ascorbate and light. Cancer Letters, 25: 297–304
  • Burger P.M., Simmons J.W. Mutagenicity and carcinogenicity of 8-MOP-UVA in cell culture. Bulletin of Cancer 1978; 65: 133–148
  • Burki J.H., Lam C.K., Wood R.D. UV-light induced mutations in synchronous CHO cells. Mutation Research 1980; 69: 347–356
  • Cerutti P.A. Prooxidant states and tumor promotion. Science 1985; 227: 375–381
  • Crute J.J., Wahl A.F., Bambara R.A., Murant R.S., Gibson S.L., Hilf R. Inhibition of mammalian DNA polymerases by hematoporphyrin derivative and photoradiation. Cancer Research 1986; 46: 153–159
  • de Mol. N.J., Beijersbergen G.M.J., Mohn G.R., Glickman B.W., Kleef P.M. On the involvement of singlet oxygen in mutation induction by 8-methoxypsoralen and UVA irradiation in E. coli K-12. Mutation Research 1981; 82: 23–20
  • Porphyrin Localization and Treatment of Tumors, D.R. Doiron, C.J. Gomer. Alan R. Liss, New York 1984
  • Dougherty T.J. Photodynamic therapy (PDT) of malignant tumors. CRC Critical Review 1984; 2: 83–116
  • Dubbelman T.M.A.R. Porphyrin-photosensitized modification of subcellular structures. Photodynamic Therapy of Tumors and Other Diseases, G. Jori, C. Perria. Libreria Progetto, PadovaItaly 1985; 93–99
  • Evensen J.F., Moan J. Photodynamic action and chromosomal damage: A comparison of hematoporphyrin derivative (HPD) and light with X-irradiation. British Journal of Cancer 1982; 45: 456–465
  • Gibson S.L., Cohen H.J., Hilf R. Evidence against the production of superoxide by photoirradiation of hematoporphyrin derivative. Photochemistry and Photobiology 1984; 40: 441–448
  • Gomer C.J. DNA damage and repair in CHO cells following hematoporphyrin photoradiation. Cancer Letters 1980; 11: 161–167
  • Gomer C.J., Dougherty T.J. Determination of 3H and 14C-hematoporphyrin derivative distribution in malignant and normal tissue. Cancer Research 1979; 39: 146–151
  • Gomer C.J., Ferrario A., Murphree A.L. The effect of localized porphyrin photodynamic therapy on the induction of tumor metastasis. British Journal of Cancer 1987; 56: 27–32
  • Gomer C.J., Rucker N., Banerjee A., Benedict W.F. Comparison of mutagenicity and induction of sister chromatid exchange in Chinese hamster cells exposed to hematoporphyrin derivative photoradiation, ionizing radiation or ultraviolet radiation. Cancer Research 1983; 43: 2622–2627
  • Gomer C.J., Rucker N., Ferrario A., Murphree A.L. Expression of potentially lethal damage in Chinese hamster cells exposed to hematoporphyrin derivative photodynamic therapy. Cancer Research 1986; 46: 3348–3352
  • Gomer C.J., Rucker N., Razum N.J., Murphree A.L. In vitro and in vivo light dose rate effects related to hematoporphyrin derivative photodynamic therapy. Cancer Research 1985; 45: 1973–1977
  • Hall E.J., Hei T.K. Oncogenic transformation with radiation and chemicals. International Journal of Radiation Biology 1985; 48(1)1–18
  • Hariharan P.V., Cortney J., Eleczko S. Production of hydroxyl radicals in cell systems exposed to hematoporphyrin and red light. International Journal of Radiation Biology 1980; 37: 691–694
  • Harisiadis L., Muller R.C., Harisiadis S., Hall E.J. Oncogenic transformation and hyperthermia. British Journal of Radiology 1980; 534: 479–482
  • Henderson B.W., Waldow S.M., Mang T.S., Potter W.R., Malone P.B., Dougherty T.J. Tumor destruction and kinetics of tumor cell death in two experimental mouse tumors following photodynamic therapy. Cancer Research 1985; 45: 572–576
  • Hilf R., Warne N.W., Smail D.B., Gibson S.L. Photodynamic inactivation of selected intracellular enzymes by hematoporphyrin derivate and their relationship to tumor cell viability in vitro. Cancer Letters 1984; 24: 1483–1488
  • Jori G., Spikes J. Photobiochemistry of porphyrins. Topics in Photomedicine, K.C. Smith. Plenum Press, New York 1984; 183–318
  • Keene J.P., Kessel D., Land E.J., Redmond R.W., Truscott T.G. Direct detection of singlet oxygen sensitized by haematoporphyrin and related compounds. Photochemistry and Photobiology 1986; 43: 117–120
  • Kennedy A.R., Fox M., Murphy G., Little J.B. Relationship between X-ray exposure and malignant transformation in C3H 10T 1/2 cells. Cell Biology 1980; 77(12)7262–7266
  • Kessel D. Sites of photosensitization by derivatives of hematoporphyrin. Photochemistry and Photobiology 1986; 44: 489–494
  • Kripke M.L., Morrison W.L., Parrish J.A. Induction and transplantation of murine skin cancers induced by methoxalen plus ultraviolet (320–400 nm) radiation. Journal of the National Cancer Institute 1983; 68: 685–690
  • Lee See K., Forbes I.J., Betts W.H. Hydroxyl radical production by hematoporphyrin derivative. Australian Society for Medical Research 1985; 15: 127–127
  • Little F.M., Gomer C.J., Hyman S., Apuzzo M. Observations in studies of quantitative kinetics of tritium labelled hematoporphyrin derivative in the normal and neoplastic rat brain model. Journal of Neuro-Oncology 1984; 21: 361–367
  • Lytle C.D., Carney P.G., Matchette S., Felten R.P., Straight R.C. Low level mutagenesis of herpes virus by photodynamic treatment using hematoporphyrin derivative. Photochemistry and Photobiology 1987; 45: 80–S, (Abstract).
  • Moan J. Porphyrin photosensitization and phototherapy. Photochemistry and Photobiology 1986; 43: 681–690
  • Moan J., Smedshammer L., Christensen T. Photodynamic effects on human cells exposed to light in the presence of hematoporphyrin-pH effects. Cancer Letters 1980; 9: 327–332
  • Oshiro Y., Balwierz P.S., Piper C.E. Selection of fetal bovine serum for use in the C3H 10T 1/2 CL8 cell transformation assay system. Environmental Mutagenesis 1982; 4: 569–574
  • Reznikoff C.A., Bertram J.S., Brankow D.W., Heidelberger C. Quantitative and qualitative studies of chemical transformation of cloned C3H mouse embryo cells sensitive to post confluence inhibition of cell division. Cancer Research 1973; 33: 3239–3249
  • Sconfienza C., van de Vorst A., Jori G. Type I and Type II mechanisms in the photo-oxidation of l-tryptophan and tryptamine sensitized by hematoporphyrin in presence and absence of sodium dodecyl sulphate micelles. Photochemistry and Photobiology 1980; 31: 351–357
  • Selman S.H., Kreimer-Birnbaum M., Klaunig J.E., Goldblatt P.J., Keck R.W., Britton S.S. Blood flow in transplantable bladder tumors treated with hematoporphyrin derivative and light. Cancer Research 1984; 44: 1924–1927
  • Spikes J.D. Porphyrin and related compounds as photodynamic sensitizers. Annals of the New York Academy of Sciences 1975; 244: 496–508
  • Suzuki F., Han A., Lankas G.R., Utsumi H., Elkind M.M. Spectral dependencies of killing, mutation, and transformation in mammalian cells and their relevance to hazards caused by solar ultraviolet radiation. Cancer Research 1981; 41: 4916–4924
  • Thomas J.P., Hall R.D., Girotti A.W. Singlet oxygen intermediary in the photodynamic action of membrane-bound hematoporphyrin derivative. Cancer Letters 1987; 35: 295–302
  • Valenzeno D.P. Photomodification of biological membrane with emphasis on single oxygen mechanisms. Photchemistry and Photbiology 1987; 46: 147–160
  • Van Steveninck J., Tijssen K., Boegheim J.P.J., van der Zee J., Dubbelman T.M.A.R. Photodynamic generation of hydroxyl radicals by hematoporphyrin derivative and light. Photochemistry and Photobiology 1986; 44: 711–716
  • Weishaupt K.R., Gomer C.J., Dougherty T.J. Identification of singlet oxygen as the cytotoxic agent in photoinactivation of a murine tumor. Cancer Research 1976; 36: 2326–2329
  • Wilson B.C., Patterson M.S. The physics of photodynamic therapy. Physics in Medicine and Biology 1986; 31: 327–360

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