48
Views
61
CrossRef citations to date
0
Altmetric
Original Article

Modulation of Radiation-induced Chromosome Aberrations by DMSO, an OH Radical Scavenger. 1: Dose—response Studies in Human Lymphocytes Exposed to 220 kV X-rays

, , , &
Pages 875-890 | Received 21 Sep 1987, Accepted 21 Jan 1988, Published online: 03 Jul 2009

References

  • Ashwood-Smith M.J. Lack of genetic damage in mammalian cells after cryopreservation at -196°C. Experimental Hematology 1979; 7: 21–26
  • Ashwood-Smith M.J. Current concepts concerning radioprotective and cryoprotective properties of dimethyl sulfoxide in cellular systems. Annals of the New York Academy of Sciences 1975; 246–256
  • Ashwood-Smith M.J. Radioprotective and cryoprotective properties of dimethyl sulfoxide in cellular systems. Annals of the New York Academy of Sciences 1967; 141: 45–62
  • Ashwood-Smith M.J. The radioprotective action of dimethyl sulphoxide and various other sulphoxides. International Journal of Radiation Biology 1961; 3: 41–48
  • Atkinson A.C. Likelihood ratios, posterior odds and information criteria. Journal of Econometrics 1981; 16: 15–20
  • Bauchinger M., Schmid E., Braselmann H. Cell survival and radiation induced chromosome aberrations. II. Experimental findings in human lymphocytes analysed in first and second post-irradiation metaphases. Radiation and Environmental Biophysics 1986; 25: 253–260
  • Braselmann H., Bauchinger M., Schmid E. Cell survival and radiation induced chromosome aberrations. I. Derivation of formulae for the determination of transmission and survival parameters of aberrations. Radiation and Environmental Biophysics 1986; 25: 243–251
  • Carrano A.V. Chromosome aberrations and radiation-induced cell death II. Predicted and observed cell survival. Mutation Research 1973; 17: 355–366
  • Chadwick K.H., Leenhouts. Monographs on Theoretical and Applied Genetics, 5: The Molecular Theory of Radiation Biology, R. Frankel, G.A.E. Gall, M. Grossman, H.F. Linskens, D. deZeeuw. Springer-Verlag, Heidelberg 1981
  • Chapman J.D., Gillespie C.J. Radiation-induced events and their time scale in mammalian cells. Advances in Radiation Biology 1981; 9: 143–198
  • Chapman J.D., Doern S.D., Reuvers A.P., Gillespie C.J., Chatterjee A., Blakely E.A., Smith K.C., Tobias C.A. Radioprotection by DMSO of mammalian cells exposed to x-rays and to heavy charged-particle beams. Radiation and Environmental Biophysics 1979; 16: 29–41
  • Chapman J.D., Reuvers A.P., Doern S.D., Gillespie C.J., Dugle D.L. Radiation chemical probes in the study of mammalian cell inactivation and their influence on radiobiological effectiveness. Fifth Symposium on Microdosimetry, J. Booz, H.G. Epert, B.G.R. Smith. Commission of the European Communities. 1976
  • Chapman J.D., Dugle D.L., Reuvers A.P., Gillespie C.J., Borsa J. Chemical radiosensitization studies with mammalian cells growing in vitro. Radiation Research. Academic Press, Inc. 1975 a; 752–760
  • Chapman J.D., Gillespie C.J., Reuvers A.P., Dugle D.L. The inactivation of Chinese hamster cells by x-rays: The effects of chemical modifiers on single- and double-events. Radiation Research 1975 b; 64: 365–375
  • Chapman J.D., Reuvers A.P., Borsa J., Greenstock C.L. Chemical radioprotection and radiosensitization of mammalian cells growing in vitro. Radiation Research 1973; 56: 291–306
  • Corn B.W., Liber H.L., Little J.B. Differential effects of radical scavengers on X-ray-induced mutation and cytotoxicity in human cells. Radiation Research 1987; 109: 100–108
  • Cox R., Masson W.K. Do radiation-induced thioguanine-resistant mutants of cultured mammalian cells arise by HGPRT gene mutation or X-chromosome rearrangement?. Nature 1978; 276: 629–630
  • Dewey W.C., Furman S.C., Miller H.H. Comparison of lethality and chromosomal damage induced by x-rays in synchronized Chinese hamster cells in vitro. Radiation Research 1970; 43: 561–581
  • Dolphin G.W., Purrott R.J. Use of radiation-induced chromosome aberrations in human lymphocytes for dosimetry. Advances in Physical and Biological Radiation Detectors. Proceedings of a Symposium. International Atomic Energy Agency, Vienna, Austria 1970; 611–622
  • Frome E.L., DuFrain R.J. Maximum likelihood estimation for cytogenetic dose-response curves. Biometrics 1986; 42: 73–84
  • Gillespie C.J., Chapman J.D., Reuvers A.P., Dugle D.L. The inactivation of Chinese hamster cells by X-rays: synchronized and exponential cell populations. Radiation Research 1975; 64: 353–364
  • Grillmaier R.E. Vorlaufige Ergebnisse von Untersuchungen an eingefrorenen und bei tiefen Temperaturen bestrahlten Lymphozyten* II. Untersuchungen der Chromosomen-Aberrationstraten bei Lymphozyten nach Bestrahlung im eingefrorenen und auf -196°C abgekuhlten Zustand. Biophysik 1971; 7: 126–132
  • Gumrich K., Virsik-Peuckert R.P., Harder D. Temperature and the formation of radiation-induced chromosome aberrations. I. The effect of irradiation temperature. International Journal of Radiation Biology 1986; 49: 665–672
  • ICRU. Quantitative concepts and dosimetry in radiobiology. Report No. 30, International Commission on Radiation Units and Measurements, Washington, D.C. 1979
  • Johansen I., Howard-Flanders P. Macromolecular repair and free radical scavenging in the protection of bacteria against x-rays. Radiation Research 1965; 24: 184–200
  • Kaul B.L. Protection against radiation-induced chromosome breakage in Vicia faba by dimethyl sulfoxide. Radiation Botany 1969; 9: 111–114
  • Lea D.E., Catcheside D.G. The mechanism of the induction by radiation of chromosome aberrations in Tradescantia. Journal of Genetics 1942; 44: 216–245
  • Littlefield L.G., Joiner E.E., Frome E.L., Colyer S.P. Modulation of radiation-induced chromosome aberrations by DMSO—an OH radical scavenger. Environmental Mutagenesis 1987 a; 9(8)61–61
  • Littlefield L.G., Joiner E.E., Frome E.L., Colyer S.P., Sayer A.M. Modification of X-ray induced chromosome aberrations-radioprotection by DMSO. Radiation Research: Proceedings of the 8th International Congress of Radiation Research, EdinburghScotland, July, 1987, E.M. Fielden, J.F. Fowler, J.H. Hendry, D. Scott. Taylor & Francis Ltd., London 1987 b; 1: 146–146
  • Littlefield L.G., Joiner E.E., Colyer S.P., Frome E.L. Effects of cryopreservation on the recovery of radiation-induced chromosome aberrations in human lymphocytes. Radiation Protection Dosimetry 1987 c; 18: 25–29
  • Lloyd D.C., Purrott R.J., Dolphin G.W., Bolton D., Edwards A.A. The relationship between chromosome aberrations and low LET radiation dose to human lymphocytes. International Journal of Radiation Biology 1975; 28: 75–90
  • Michaels H.B., Peterson E.C., Epp E.R. Effects of modifiers of the yield of hydroxyl radicals on the radiosensitivity of mammalian cells at ultrahigh dose rates. Radiation Research 1983; 95: 620–636
  • Mikaelsen, Knut. The protective effect of glutathione against radiation-induced chromosome aberrations. Science 1952; 116: 172–174
  • Okada S., Nakamura N., Sakai K. Radioprotection of intracellular genetic material. Radioprotectors and Anticarcinogens, O.F. Nygaard, M.G. Simic. Academic Press, New York 1983; 339–356
  • Perry P., Wolff S. New Giemsa method for the differential staining of sister chromatids. Nature 1974; 251: 156–158
  • Prosser J.S., Stimpson L.D. The influence of anoxia or oxygenation on the induction of chromosome aberrations in human lymphocytes by 15-MeV neutrons. Mutation Research 1981; 84: 365–373
  • Prosser J.S., White C.M., Edwards A.A. The effect of oxygen concentration on the x-ray induction of chromosome aberrations in human lymphocytes. Mutation Research 1979; 61: 287–295
  • Revell S.H. The breakage-and-reunion theory and the exchange theory for chromosomal aberrations induced by ionizing radiation: a short history. Advances in Radiation Biology 1974; 4: 367–416
  • Reuvers A.P., Greenstock C.L., Borsa J., Chapman J.D. Studies on the mechanism of chemical radioprotection by dimethyl sulphoxide. International Journal of Radiation Biology 1973; 24: 533–536
  • Roots R., Okada S. Estimation of life times and diffusion distance of radicals involved in x-ray-induced DNA strand breaks or killing of mammalian cells. Radiation Research 1975; 64: 306–320
  • Roots S., Okada S. Protection of DNA molecules of cultured mammalian cells from radiation-induced single-strand scissions by various alcohols and SH compounds. International Journal of Radiation Biology 1972; 21: 329–342
  • Sasaki M.S., Matsubara S. Free radical scavenging in protection of human lymphocytes against chromosome aberration formation by gamma-ray irradiation. International Journal of Radiation Biology 1977; 32: 439–445
  • Sax K. Types and frequencies of chromosomal aberrations induced by X-rays. Cold Spring Harbor Symposium 1941; 9: 93–103
  • Savage J.R.K. Sites of radiation-induced chromosome exchanges. Current Topics in Radiation Research 1970; 6: 129–194
  • Schwartz J.L., Giovanazzi S.M., Grdina D. (1987) 2-[(Aminopropyl)Amino] ethanethiol (WR1065)-mediated reduction in 60Co gamma ray and fission-spectrum neutron-induced chromosome damage in V79 cells. Radiation Research: Proceedings of the 8th International Congress of Radiation Research, EdinburghScotland, July, 1987, E.M. Fielden, J.F. Fowler, J.H. Hendry, D. Scott. Taylor & Francis, London, 1: 145–145
  • Virsik R.P., Harder D. Numerical relationship between cells with radiation-induced chromosome aberrations and cells lethally injured by radiation. Radiation and Environmental Biophysics 1980; 18: 73–77
  • Virsik R.P., Harder D. Effect of L-cysteine on the dose-effect relationship for chromosome aberrations in irradiated human lymphocytes. International Journal of Radiation Biology 1982; 42: 211–214
  • Ward J.F. Symposium on radical processes in radiobiology and carcinogenesis. Some biochemical consequences of the spatial distribution of ionizing radiation-produced free radicals. Radiation Research 1981; 86: 185–195
  • Ward J.F. Biochemistry of DNA lesions. Radiation Research 1985; 104: S103–S111
  • Ward J.F., Blakely W.F., Joner E.I. Mammalian cells are not killed by DNA single-strand breaks caused by hydroxyl radicals from hydrogen peroxide. Radiation Research 1985; 103: 383–392
  • Wolff, Sheldon. Some aspects of the chemical protection against radiation damage to Vicia faba chromosomes. Genetics 1954; 39: 356–364

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.