50
Views
43
CrossRef citations to date
0
Altmetric
Original Article

Microdosimetric Specification of Radiation Quality in Neutron Radiation Therapy

, &
Pages 865-883 | Published online: 03 Jul 2009

References

  • Amols H.I., Dicello J.F., Awschalom M., Coulson L., Johnsen S.W., Theus R.B. Physical characterization of neutron beams produced by protons and deuterons of various energies bombarding beryllium and lithium targets of several thicknesses. Medical Physics 1977; 4: 486–493
  • Barendsen G.W. Impairment of the proliferative capacity of human cells in culture by α-particles with differing linear-energy transfer. International Journal of Radiation Biology 1964; 8: 453–466
  • Battermann J.J., Hart A.A.M., Breur K. Dose-effect relations for tumour control and complication rate after fast neutron therapy for pelvic tumours. British Journal of Radiology 1981; 54: 899–904
  • Beach J.L., Milavickas L.R. Microdosimetric measurements of radiation quality variations in homogeneous phantoms irradiated by fast neutrons. Medical Physics 1982; 9: 52–59
  • Beauduin M., Gueulette J., de Coster B.M., Gregoire V., Octave-Prignot M., Vynckier S., Wambersie A. Radiobiological intercomparisons of fast neutron beams used in therapy. Proceedings of the EORTC-Heavy Particles Therapy Group Meeting, Munich, October 1987. Strahlentherapie und Onkologie 1989; 165: 263–267
  • Bewley D.K., Cullen B.M., Astor M., Hall E.J., Blake S.W., Bonnett D.E., Zaider M. Changes in biological effectiveness of the neutron beam at Clatterbridge (62 MeV p on Be) measured with cells in vitro. British Journal of Radiology 1989; 62: 344–347
  • Binns P.J., Hough J.H. Lineal energy measurements in two fast neutron beams—d(16)+Be and p(66)+Be. Proceedings of the 6th Symposium on Neutron Dosimetry, Munchen, 1987, edited by H. Schraube, G. Burger and J. Booz. Radiation Protection Dosimetry 1988; 23: 385–388
  • Booz J., Fidorra J. Microdosimetric investigations on collimated fast neutron beams for radiation therapy: II. The problem of radiation quality and RBE. Physics Medicine and Biology 1981; 26: 43–56
  • Bridier A., Fache P. Etudes dosimétriques et microdosimétriques de faisceaux de particules à transfer linéique d'énergie élevée. Rapport CEA-R-4655, Université Paul Sabatier, Toulouse 1975, Thesis
  • Cox R., Thacker J., Goodhead D.T., Munson R.J. Mutation and inactivation of mammalian cells by various ionising radiations. Nature 1977; 267: 425–427
  • Goodhead D.T. (1987) Biophysical models of radiation action. Introductory review. Proceedings of the 8th International Congress of Radiation Research, Edinburgh, July, 1987, E.M. Folden, J.F. Fowler, J.H. Hendry, D. Scott. Taylor & Francis, London, 2: 306–311
  • Gueulette J., Breteau N., Sabattier R., Wambersie A. RBE of p(34) + Be neutrons for early intestinal tolerance in mice. Radiobiological intercomparison between Orléans (p(34) + Be neutrons) and Louvain-la-Neuve (d(50) + Be neutrons). Proceedings of the EORTC workshop on high-LET particles in radiation therapy, Orléans, May 1983, edited by J. Battermann, J. P. Le Bourgeois, A. Wambersie and N. Breteau. Journal Européen de Radiothérapie 1984; 5: 175–179
  • Hall E.J., Kellerer A. Review of RBE data for cells in culture. Proceedings of the 3rd Meeting on ‘Fundamental and practical aspects of the application of fast neutrons and other high LET particles in clinical radiotherapy’, G.W. Barendsen, J.J. Broerse, J.J. Breur. 1979; 171–174
  • Hartmann G., Menzel H.G., Shuhmacher H. (1981) Different approaches to determine effective quality factors and dose equivalent using the Rossi-counter. Proceedings of the 4th Symposium on Neutron Dosimetry, München, 1981, G. Burger, H.G. Ebert. CEC, Luxembourg, 225–236, EUR 7448
  • Heintz P.H., Johnsen S.W., Peek N.F. Neutron energy spectra and dose distribution spectra of cyclotron produced neutron beams. Medical Physics 1977; 4: 250–254
  • ICRU. Microdosimetry. ICRU Report 36, International Commission on Radiation Units and Measurements, Washington, D.C. 1983
  • Joiner M.C., Field S.B. The response of mouse skin to irradiation with neutrons from the 62 MeV cyclotron at Clatterbridge, UK. Radiotherapy and Oncology 1988; 12: 153–166
  • Kellerer A.M., Rossi H.H. The theory of dual radiation action. Current Topics in Radiation Research Quarterly 1972; 8: 85–157
  • Kliauga P., Bonnett D., Waker A. A microdosimetric comparison of high energy neutron therapy facilities: Clatterbridge and M. D. Anderson. Proceedings of the 10th Symposium on Microdosimetry, Rome, 1989. Radiation Protection Dosimetry 1990, in press
  • Menzel H.G., Schuhmacher H. (1981) Comparison of microdosimetric characteristics of four fast neutron therapy facilities. Proceedings of the 7th Symposium on Microdosimetry, Oxford, 1980, J. Booz, H.G. Ebert, H.D. Hartfield. CEC, Luxembourg, 1217–1232, EUR 7147
  • Menzel H.G. (1984) Proportional counter measurements in neutron therapy beams. IAEA STI/PUB/643. Proceedings of a Symposium on Advances in Dosimetry for Neutrons and Heavy Charged Particles for Therapy Applications, Vienna, 1982. Vienna, 105–126, IAEA-AG-371/3
  • Menzel H.G., Waker A.J., Hartmann G. Radiation quality studies of fast neutron therapy beam. Proceedings of the 5th Symposium on Microdosimetry, J. Booz, H.G. Ebert, B.R.G. Smith. CEC, Luxembourg 1976; 591–608, EUR 5452
  • Mijnheer B.J., Battermann J.J., Wambersie A. What degree of accuracy is required and can be achieved in photon and neutron therapy?. Radiotherapy and Oncology 1987; 8: 237–252
  • Oliver G.D., Walter J., Grant W.H., III, Amathers J.B. Radiation quality of fields produced by 16, 30 and 50 MeV deuterons on beryllium. Radiation Research 1975; 61: 366–373
  • Pihet P., Gueulette J., Menzel H.G., Grillmaier R.E., Wambersie A. Use of microdosimetric data of clinical relevance in neutron therapy planning Proceedings of the 6th Symposium on Neutron Dosimetry, Munich, October 1987. Radiation Protection Dosimetry 1988; 23: 471–474
  • Pihet P., Menzel H.G., Schmidt R., Beauduin M., Wambersie A. Biological weighting function for RBE specification of neutron therapy beams. Intercomparison of 9 European Centres. Proceedings of the 10th Symposium on Microdosimetry, Rome, 1989. Radiation Protection Dosimetry 1990, in press
  • Pihet P. Etude microdosimetrique de faisceaux de neutrons de haute energie. Applications dosimetriques et radiobiologiques. Universite Catholique de Louvain, Louvain-la-Neuve 1989, Thesis
  • Schmidt R., Hess A. Microdosimetric investigations for neutron therapy. Proceedings of the 6th Symposium on Neutron Dosimetry, Munich, October 1987. Radiation Protection Dosimetry 1988a; 23: 393–396
  • Schmidt R., Hess A. Component evaluation of event size spectra for a clinical 14 MeV neutron beam. Medical Physics 1988b; 15: 343–347
  • Stafford M.P., Horton J.L., Almond P.R. A microdosimetric characterization of a cyclotron-produced therapeutic neutron beam. Medical Physics 1987; 14: 1015–1019
  • Stinchcomb T.G., Kuchnir F.T., Myrianthopoulos L.C., Horton J.L., Roberts W.K. Correlation of microdosimetric measurements with relative biological effectiveness from clinical experience for two neutron therapy beams. Medical Physics 1986; 13: 201–206
  • Van Dam J. Radiobiological characteristics of high-LET radiations. Katholieke Universiteit Leuven, Leuven 1984, Thesis (Geaggregeerde voor het Hoger Onderwijs)
  • Varma M.N., Bond V.P. Empirical evaluation of cell critical volume dose vs. cell response function for pink mutations in Tradescantia. Proceedings of the 8th Symposium on Microdosimetry, Jülich, September 1982. CEC, EUR 8395 EN, Luxembourg 1982; 439–450
  • Waker A.J., Maughan R.L. Microdosimetric investigation of a fast neutron radiobiology facility utilising the d(4)-9Be reaction. Physics in Medicine and Biology 1986; 31: 1281–1290
  • Wambersie A., Gueulette J. (1984) Accuracy required in radiotherapy and in neutron therapy. IAEA STI/PUB/643. Proceedings of the Symposium on Advances in Dosimetry for Neutrons and Heavy Charged Particles for Therapy Applications, Vienna, 1982. IAEA, Vienna, 11–26, IAEA-AG-371/1
  • Wambersie A., Battermann J.J. (1985) Practical problems related to RBE in neutrontherapy. Proceedings of the 3rd Meeting on Progress in Radio-Oncology, Vienna, 1985. ICRO, 155–162, Progress in Radio-Oncology III
  • Wambersie A., Pihet P., Menzel H.G. The role of microdosimetry in radiotherapy. Proceedings of the 10th Symposium on Microdosimetry, Rome, 1989. Radiation Protection Dosimetry 1990, in press
  • Weaver K., Bichsel H., Eenmaa J., Wootton P. Measurement of photon dose fraction in a neutron radiotherapy beam. Medical Physics 1977; 4: 379–386
  • Wilson K.S.J., Field S.B. Further measurement of LET spectra with a 10 cm spherical Rossi counter. Proceedings of the 2nd Symposium on Microdosimetry, H.G. Ebert. CEC, EUR 4452, Luxembourg 1970; 137–137
  • Zaider M., Brenner D.J. On the microdosimetric definition of quality factors. Radiation Research 1985; 103: 302–316
  • Zeitz L., Canada T.R., Djordjevic B., Dymbort G., Freeman R., McDonald J.C., O'Neil J., Laughlin J.S. A biological determination of the variation of fast neutrons field quality with depth, RBE and OER. Radiation Research 1975; 63: 211–225
  • Zywietz F., Menzel H.G., Van Beuningen D., Schmidt R. A biological and microdosimetric intercomparison of 14 MeV d-T neutrons and 6 MeV cyclotron neutrons. International Journal of Radiation Biology 1982; 42: 223–228

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.