17
Views
15
CrossRef citations to date
0
Altmetric
Original Article

Radiosensitization by Metal Complexes of 4(5)-nitroimidazole

&
Pages 947-958 | Received 14 Jul 1989, Accepted 10 Nov 1989, Published online: 03 Jul 2009

References

  • Abrams M., Jiondomenico C., Vollano J.F., Schwartz D.H. A convenient preparation of the trichlorodiammineplatinate ion. Inorganic Chimica Acta 1987; 131: 3–4
  • Adams G.E., Fielden E.M., Hardy C., Millar B.C., Stratford I.J., Williamson C. Radiosensitization of hypoxic mammalian cells in vitro by some 5-substituted-4-nitroimidazoles. International Journal of Radiation Biology 1981; 40: 153–161
  • Adams G.E., Sheldon P.W., Stratford I.J. Evaluation of novel radiation sensitizers in vitro and in vivo. International Journal of Radiation Oncology, Biology, Physics 1982; 8: 419–421
  • Bales J.R., Mazid M.A., Sadler P.J., Aggarwal A., Kuroda R., Neidle S., Gilmour D.W., Peart B.J., Ramsden C.A. Platinum (II) complexes of nitroimidazoles: synthesis, characterisation, and X-ray crystal structures of cis-dichlorobis [1-(2-hydroxyethyl)-2-hydroxymethyl-5-nitroimidazole]platinum (II) and trans-dichlorobis [1-(2-hydroxy-3-methoxypropyl)-2-nitroimidazole] platinum (II). Journal of the Chemical Society, Dalton Transactions 1985; 795–802
  • Butler J., Hoey B.M., Swallow A.J. The radiation chemistry of some platinum-containing radiosensitizers and related compounds. Radiation Research 1985; 102: 1–13
  • Chan P.K.L. Ruthenium nitroimidazole complexes as radiosensitizers, Ph.D. thesis. University of British Columbia. 1988
  • Chan P.K.L., Skov K.A., Farrell N.P., James B.R. A new ruthenium radiosensitizer: RuCl2(DMSO)2(4-nitroimidazole)2. International Journal of Radiationa Oncology Biology, Physics 1986; 12: 1059–1062
  • Chan P.K.L., Skov K.A., James B.R. Further studies on toxic and radiosensitizing properties of ruthenium complexes of 4-nitroimidazoles. International Journal of Radiation Biology 1987; 52: 49–55
  • Chan P.K.L., Chan P.K.H., Frost D.C., James B.R., Skov K.A. Ruthenium (II) complexes of 4-nitroimidazoles: Their characterization solution chemistry and radiosensitizing activity. Canadian Journal of Chemistry 1988; 66: 117–122
  • Chan P.K.L., James B.R., Frost D.C., Chan P.K.H., Hu H-L., Skov K.A. Effects of halide (X) and sulphoxide (R2SO) replacement within the ruthenium(II) nitroimidazole complexes, RuX2(R2SO)m(nitroimidazole)n, m = 1-3, n=1 or 2: their characterization, solution chemistry, radiosensitizing activity, and related properties. Canadian Journal of Chemistry 1989; 67: 508–516
  • Evans D., Green M. The use of metal complexes to counter and exploit tumour tissue hypoxia in radio- and chemo-therapy. Journal of Inorganic Biochemistry 1989; 36: 286–286, (Abstract)
  • Farrell N.P., Skov K.A. Radiosensitizers targeted to DNA using platinum. Synthesis, characterization and DNA binding of cis-[PtCl2(NH3)(radiosensitizer)]. Journal of the Chemical Society, Chemical Communications 1987; 1043–1044
  • Farrell N.P., Fonseca E., Skov K.A. Tautomeric forms of 4(5)-nitroimidazole stabilized on platinum: synthesis and characterization, and crystal and molecular structure of cis-[dichlorobis(4-nitroimidazole)platinum(II)]. For submission to Inorganic Chemistry 1990
  • Farrell N.P., Gomes Carneiro T., Einstein F.W.B., Jones T., Skov K.A. Synthesis and characterization of nitroimidazole complexes of platinum and palladium and the crystal and molecular structure of trans-dichlorobis(misonidazole)Platinum(II). Inorganica Chimica Acta 1984; 92: 61–66
  • Farrell N.P., Hu T.T.H., Souchard J.P., Wimmer F.L., Cros S., Johnson N.P. Cytostatic trans-platinum(II) complexes. Journal of Medical Chemistry 1989; 32: 2240–2241
  • Grimison A., Ridd J.H., Smith B.V. The mechanisms of N-substitution in glyoxaline derivatives. Part I: Introduction, and study of prototropic equilibria involving 4(5)-Nitroglyoxaline. Journal of the Chemical Society 1960; 1352–1352
  • Heindel N.D. Enhancement of tumor incorporation of radiosensitizers: Some suggestions from a radiopharmaceutical viewpoint. Radiation Sensitizers: their use in the clinical management of cancer, L.W. Brady. Masson Publishing, New York 1980; 91–97
  • Lippard S. New chemistry of an old molecule cis-[Pt(NH3)2Cl2]. Science 1982; 218: 1075–1082
  • Ma H., Hardy C.R., O'Neill P. Formation of halide-ions on one-electron reduction of halogenated nitroimidazoles in aqueous solution. A radiolytic study. International Journal of Radiation Biology 1982; 41: 151–160
  • Reedijk J., Fichtinger-Schepman A.M.J., van Ooosterom A.T., van de Putte P. Platinum amine coordination compounds as anti-tumor drugs, molecular aspects of the mechanism of action. Structure and Bonding. Springer-Verlag, Berlin Heidelberg 1987; 67: 53–89
  • Skov K.A., Farrell N.P. Binding mode of 2-amino-5-nitrothiazole (ANT) in platinum complexes trans-[PtCl2(ANT)2] affects DNA binding, toxicity and radio-sensitizing ability. International Journal of Radiation Biology 1987; 52: 289–297
  • Skov K.A., Adomat H., Konway D.C., Farrell N.P. Assessment of DNA binding of platinum radiosensitizer complexes by inhibition of restriction enzymes. Chemico-Biological Interactions 1987a; 62: 117–129
  • Skov K.A., Farrell N.P., Adomat H. Platinum complexes with one radiosensitizing ligand [PtCl2(NH3)(sensitizer)]. Radiation Research 1987b; 112: 273–282
  • Stratford I.J., Williamson C., Hardy C. Cytotoxic properties of a 4-nitroimidazole (NSC 38087): A radiosensitizer of hypoxic cells in vitro. British Journal of Cancer 1981; 44: 109–109
  • Stratford I.J., Hoe S., Adams G.E., Hardy C., Williamson C. Abnormal radiosensitizing and cytotoxic properties of ortho-substituted nitroimidazoles. International Journal of Radiation Biology 1983; 43: 31–43
  • Stratford I.J., Adams G.E., Hardy C., Hoe S., O'Neill P., Sheldon P.W. Thiol reactive nitroimidazoles: radiosensitization studies in vitro and in vivo. International Journal of Radiation Biology 1984; 46: 731–745
  • Storm C.B., Freeman C.M., Butcher R.J., Turner A.H., Rowan N.S., Johnson F.O., Sinn E. Nitration of metal ion coordinated imidazole and the crystal structure of pentaammine (4-nitroimidazolato)cobalt(III) chloride. Inorganic Chemistry 1983; 22: 678–682
  • Varnes M.E., Biaglow J.E. Interactions of the carcinogen 4-nitroquinoline 1-oxide with the non-protein thiols of mammalian cells. Cancer Research 1979; 39: 2960–2965
  • Wardman P. The kinetics of the reaction of ‘anomalous’ 4-nitroimidazole radiosensitizers with thiols. International Journal of Radiation Biology 1982; 41: 231–235
  • Watts M.E., Dennis M.F., Stratford M.R.L., Wardman P. Glutathione-reactive nitro compounds as radiosensitizers: Mechanistic and therapeutic implications. International Journal of Radiation Oncology, Biology, Physics 1986; 12: 1135–1138
  • Wong T.W., Whitmore G.F., Gulyas S. Studies on the toxicity and radiosensitizing ability of misonidazole under conditions of prolonged incubation. Radiation Research 1978; 75: 541–555

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.