References
- Brown J.M. Clinical perspectives for the use of new hypoxic cell sensitizers. International Journal of Radiation Oncology, Biology, Physics 1982; 8: 1491–1497
- Brown J.M. Clinical trials of radiosensitizers: what should we expect?. International Journal of Radiation Oncology, Biology, Physics 1984; 10: 425–429
- Brown J.M., Workman P. Partition coefficient as a guide to the development of radiosensitizers which are less toxic than misonidazole. Radiation Research 1980; 82: 171–190
- Coleman C.N. Hypoxic cell radiosensitizers: Expectation and progress in drug development. International Journal of Radiation Oncology, Biology, Physics 1985; 11: 323–329
- Coleman C.N., Urtasun R.C., Wasserman T.H., Hancock S., Harris J.W., Halsey J., Hirst V.K. Initial report of the Phase I trial of the hypoxic cell radiosensitizer SR-2508. International Journal of Radiation Oncology, Biology, Physics 1984; 10: 1749–1753
- Coleman C.N., Wasserman T.H., Urtasun R.C., Halsey J., Hirst V.K., Hancock S., Phillips T.L. Phase I trial of the hypoxic cell radio-sensitizer SR-2508: the results of the five to six week drug schedule. International Journal of Radiation Oncology, Biology, Physics 1986; 12: 1105–1108
- Dische S., Saunders M.I., Flockhart I.R., Lee M.E., Anderson P. Misonidazole—a drug for trial in radiotherapy and oncology. International Journal of Radiation Oncology, Biology, Physics 1979; 5: 851–860
- Fujita T., Iwasa J., Hannsch C. A new substitute constant, π, derived from partition coefficients. Journal of the American Chemical Society 1964; 86: 5175–5180
- McNally N.J., Denekamp J., Sheldon P., Flockhart I.R., Stewart F.A. Radiosensitization by Misonidazole (Ro 07-0582). The importance of timing and tumour concentration of sensitizer. Radiation Research 1978; 73: 568–580
- Murayama C., Tanaka N., Miyamoto Y., Sakaguchi M., Mori T. In vitro and in vivo radiosensitizing effects of 2-nitroimidazole derivatives with sugar component. Strahlen Therapie und Onkologie 1987; 163: 385–390
- Powell H.C., Myers R.R. The blood-nerve barrier and the pathologic significance of nerve edema. Implications of the Blood-brain Barrier and its Manipulation, E.A. Neuwelt. Plenum, New York 1989; 1: 199–202
- Roberts J.T., Bleehen N.M., Workman P., Walton M.I. A phase I study of the hypoxic cell radiosensitizer Ro-03-8799. International Journal of Radiation Oncology, Biology, Physics 1984; 10: 1755–1758
- Rowland M., Tozer T.N. Clinical Pharmacokinetics: Concepts and Applications. Lea & Febiger, Philadelphia 1980; 288–290
- Sasai S., Shibamoto Y., Takahashi M., Abe M., Wang J., Zhou L., Nishimoto S., Kagiya T. A new potent 2-nitroimidazole nucleoside hypoxic cell radiosensitizer, RP170. Japanese Journal of Cancer Research 1989; 80: 1113–1118
- Saunders M.I., Anderson P.J., Bennett M.H., Dische S., Minchinton A., Stratford M.R.L., Tothill M. The clinical testing of Ro 03-8799—pharmacokinetics, toxicology, tissue and tumor concentrations. International Journal of Radiation Oncology, Biology, Physics 1984; 10: 1759–1763
- Shibamoto Y., Nishimoto S., Mi F., Sasai K., Kagiya T., Abe M. Evaluation of various types of new hypoxic cell sensitizers using the EMT6 single cell-spheroid-solid tumour system. International Journal of Radiation Biology 1987; 52: 347–357
- Shibamoto Y., Nishimoto S., Shimokawa K., Hisanaga Y., Zhou L., Wang J., Sasai K., Takahashi M., Abe M., Kagiya T. Characteristics of fluorinated nitroazoles as hypoxic cell radiosensitizers. International Journal of Radiation Oncology, Biology, Physics 1989; 16: 1045–1048
- Wasserman T.H., Phillips T.L., Johnson R.J., Gomer C.J., Lawrence G.A., Sadee W., Marques R.A., Levin V.A., VanRaalte G. Initial United States clinical and pharmacologic evaluation of misonidazole (Ro-07-0582), a hypoxic cell radiosensitizer. International Journal of Radiation Oncology, Biology, Physics 1979; 5: 775–786
- White R.A.S., Workman P., Brown J.M. The pharmacokinetics and tumour and neural tissue penetrating properties of SR-2508 and SR-2555 in the dog—hydrophilic radiosensitizers potentially less toxic than misonidazole. Radiation Research 1980; 84: 542–561
- Williams M.V., Denekamp J., Minchinton A.I., Stratford M.R.L. In vivo assessment of basic 2-nitroimidazole radiosensitizers. British Journal of Cancer 1982; 46: 127–137