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Original Article

Mutation Induction in V79 Chinese Hamster Cells by Very Heavy Ions

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Pages 975-987 | Received 30 Jan 1990, Accepted 10 May 1990, Published online: 03 Jul 2009

References

  • Baltschukat K., Horneck G., Bücker H., Facius R. Mutation induction in spores of Bacillus subtilis by accelerated heavy ions. Radiation and Environmental Biophysics 1986; 25: 183–187
  • Barkas W.H. Nuclear Research Emulsion. Academic Press, New York 1963; 1: 349–424
  • Butts J.J., Katz R. Theory of RBE for heavy ion bombardment of dry enzymes and viruses. Radiation Research 1967; 30: 855–871
  • Chu E.H.Y., Malling H.V. Mammalian cell genetics. II. Chemical induction of specific locus mutations in Chinese hamster cells in vitro. Proceedings of the National Academy of Sciences, USA 1968; 61: 1306–1312
  • Cox R., Masson W.K. Do radiation-induced thioguanine resistant mutants of cultured mammalian cells arise by HGPRT gene mutation or X-chromosome rearrangement?. Nature 1978; 276: 629–630
  • Cox R., Masson W.K. Mutation and inactivation of cultured mammalian cells exposed to beams of accelerated heavy ions. III. Human diploid fibroblasts. International Journal of Radiation Biology 1979; 36: 149–160
  • Cox R., Thacker J., Goodhead D.T., Munson R.J. Mutation and inactivation of mammalian cells by various ionizing radiations. Nature 1977; 267: 425–427
  • Geard C.R. Initial changes in the cell cycle progression of Chinese hamster V79 cells induced by high LET charged particles. Radiation Research 1980; 83: 696–709
  • Gibbs R.A., Canalaris J., Hodgson G.S., Martin R.F. Molecular characterization of a 125J decay and X-ray induced HPRT-mutants in CHO cells. International Journal of Radiation Biology 1987; 51: 193–199
  • Gillin F.D., Roufa D., Beaudet A.L., Caskey C.T. 8-Azaguanine resistance in mammalian cells. Genetics 1972; 72: 239–252
  • Goodhead D.T., Thacker J., Munson R.J., Cox R. Mutation and inactivation of cultured mammalian cells exposed to beams of accelerated heavy ions. IV. Biophysical interpretation. International Journal of Radiation Biology 1980; 37: 135–167
  • ICRP. Recommendations of the International Commission on Radiological Protection. 1977, (Annual), ICRP 1
  • Kiefer J. Cellular and subcellular effects of very heavy ions. International Journal of Radiation Biology 1985; 48: 873–892
  • Kiefer J., Rase S., Schneider E., Straaten H., Kraft G., Liesem H. Heavy ion effects on yeast cells: Induction of canavanine resistant mutants. International Journal of Radiation Biology 1982; 42: 591–600
  • Kiefer J., Straaten H. A track structure model based on classical collision dynamics. Physics in Medicine and Biology 1986; 31: 1201–1209
  • Kiefer J., Straaten H. Calculations of energy deposition in microscopical sites by heavy ions. Abstracts of the Third Workshop on Heavy Charged Particles in Biology and Medicine. GSI-report, 87-11, A7, 1987
  • Knaap A.G.A.C., Simons J.W.I.M. A mutational assay system for L5178Y mouse lymphoma cells using HPRT deficiency as market. The occurrence of a long expression time for mutations induced by X-rays and EMS. Mutation Research 1975; 30: 97–110
  • Kraft G. Radiobiological effects of very heavy ions: inactivation, induction of chromosome alterations and strand breaks. Nuclear Science Application 1987; 3: 1–28
  • Kraft G., Daues H.W., Fischer B., Kopf U., Liebold H.P., Quis D., Stelzer H., Kiefer J., Schöpfer F., Schneider E., Weber K., Wulf H., Dertinger H. Irradiation chamber and sample changer for biological samples. Nuclear Instruments and Methods 1980; 168: 175–179
  • Kranert T., Schneider E., Kiefer J. Heavy ion irradiation induces mutations in mammalian cells. GSI-Report 1988; 88-1: 228–228
  • Kranert T., Schneider E., Kiefer J. Mutation induction in mammalian cells by very heavy ions. Proceedings of the 21st Annual Meeting of the European Society of Radiation Biology 1988, Israel. E. Riklis. VCH, Weinheim/Deerfield 1990
  • Kronenberg A., Blakely E.A. Locus specificity for mutation induction in human lymphoblastoid cells: LET effects. Proceedings of the CEC/DOE Workshop on Cell Transformation Systems Relevant to Radiation-induced Cancer in Man, DublinIreland, 1989, (in press)
  • Kronenberg A., Little J. Mutation induction by low doses of fast neutrons, X-rays, or selected heavy ions in a human B-lymphoblastoid cell line. Abstracts of the Third Workship on Heavy Charged Particles in Biology and Medicine 1987; 11-87: D16–D16, GSI-REPORT
  • Kronenberg A., Little J. Locus specificity for mutation induction in human cells exposed to accelerated heavy ions. International Journal of Radiation Biology 1989; 55: 913–924
  • Liber H.L., Yandell B.W., Little J.B.A. Comparison of mutations induction at the TK- and HGPRT-locus in human lymphoblastoid cells. Quantitative differences are due to an additional class of mutations at the autosomal TK-locus. Mutation Research 1989; 216: 9–17
  • Olivie P.L. Cell contact during expression of radiation mutation in Chinese hamster V79 spheroids. Radiation Research 1984; 99: 36–43
  • Thacker J. The nature of mutants induced by ionizing radiation in cultured hamster cells. III. Molecular characterization of HPRT deficien mutants induced by gammarays or alpha-particles showing that the majority have deletions of all or part of the HPRT gene. Mutation Research 1986; 160: 267–275
  • Thacker J., Stretch A., Stephens M.A. Mutation and inactivation of cultured mammalian cells exposed to beams of accelerated heavy ions. II. Chinese hamster V79 cells. International Journal of Radiation Biology 1979; 36: 137–148
  • Thilly W.G., Deluca J.G., Furth E.E. Genelocus mutation assays in diploid human lymphoblast lines. Chemical Mutagens, F.J. De Serres, A. Hollaender. Plenum, New York 1980; 6: 331–364
  • Vrieling H., Simons J.W.I.M., Arwet F., Natarajan A.T., van Zeeland A.A. Mutations induced by Xrays at the HPRT-locus in cultured Chinese hamster cells are mostly large deletions. Mutation Research 1985; 144: 281–286
  • Waligorsky M.P.R., Sinclair G.L., Katz R. Radiosensitivity parameters for neoplastic transformations in C3H 10T½ cells. Radiation Research 1987; 111: 424–437
  • Wulf H. Der Einfluss von Schwerionenstrahlen auf das Überleben und Wachstum von Säugetierzellen in vitro. GSI-Report 3-83. 1983

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