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Original Article

Establishment of a Novel Immortalized Cell Line from Ataxia Telangiectasia Fibroblasts and Its Use for the Chromosomal Assignment of Radiosensitivity Gene

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Pages 989-997 | Received 07 Feb 1990, Accepted 15 May 1990, Published online: 03 Jul 2009

References

  • Arlett C.F., Green M.H.L., Priestley A., Harcourt S.A., Mayne L.V. Comparative human cellular radiosensitivity: I The effect of SV40 transformation and immortalization on the gamma-irradiation survival of skin derived fibroblasts from normal individuals and from ataxia-telangiectasia patients and heterozygotes. International Journal of Radiation Biology 1988; 54: 911–928
  • Birnboim H.C., Doly J. A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acids Research 1979; 7: 1513–1517
  • Boder E. Ataxia-telangiectasia: an overview. Ataxia-Talangiectasia: Genetics, Neuropathology and Immunology of a Degenerative Disease of Childhood, R.A. Gatti, M. Swift. Alan R. Liss, New York 1985; 1–63
  • Gatti R.A., Berkel I., Boder E., Braedt G., Charmley P., Concannon P., Ersoy F., Foroud T., Jaspers N.G.J., Lange K., Lathrop G.M., Leppert M., Makamura Y., O'Connell P., Paterson M., Salser W., Sanal O., Silver J., Sparkes R.S., Susi E., Weeks D.E., Wei S., White R., Yoder F. Localization of an ataxia-telangiectasia gene to chromosome 11q22-23. Nature 1988; 336: 577–580
  • Gluzman Y., Frisque R.J., Sambrook J. Origin-defective mutants of SV40. Cold Spring Harbor Symposia and Quantitative Biology 1980; 44: 293–299
  • Graham F.L., van der Eb A.J. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology 1973; 52: 456–467
  • Hanawalt P.C., Sarasin A. Cancer-prone hereditary diseases with DNA processing abnormalities. Trends in Genetics 1986; 2: 124–129
  • Hashimoto T., Nakano Y., Owada M.K., Kakunaga T., Furuyama J.I. Establishment of cell lines derived from ataxia telangiectasia and xeroderma pigmentosum patients with high radiation sensitivity. Mutation Research 1986; 166: 215–220
  • Jaspers N.G.J., Painter R.B., Paterson M.C., Kidson C., Inoue T. Complementation analysis of ataxia telangiectasia. Ataxia-Telangiectasia: Genetics, Neuropathology and Immunology of a Degenerative Disease of Childhood, R.A. Gatti, M. Swift. Alan R. Liss, New York 1985; 147–162
  • Kapp L.N., Painter R.B. Stable radioresistance in ataxia-telangiectasia cells containing DNA from normal human cells. International Journal of Radiation Biology 1989; 56: 667–675
  • Koi M., Shimizu M., Morita H., Yamada H., Oshimura M. Construction of mouse A9 clones containing a single human chromosome tagged with neomycin-resistance gene via microcell fusion. Japanese Journal of Cancer Research 1989; 80: 413–418
  • Komatsu K., Kodama S., Okumura Y., Koi M., Oshimura M. Restoration of radiation resistance in ataxia-telangiectasia cells by the introduction of normal human chromosome 11. Mutation Research 1990; 235: 59–63
  • Mayne L.V., Jones T., Dean S.W., Harcourt S.A., Lowe J.E., Priestley A., Steingrimsdottir H., Sykes H., Green M.H.L., Lehmann A.R. SV40-transformed normal and DNA-repair-deficient human fibroblasts can be transfected with high frequency but retain only limited amounts of integrated DNA. Gene 1988; 66: 65–76
  • Murnane J.P., Fuller L.F., Painter R.B. Establishment of a permanent pSV ori--transformed ataxia-telangiectasia cell line. Experimental Cell Research 1985; 158: 119–126
  • Nordeen S.K., Schaefer V.G., Edgell M.H., Hutchinson C.A., Schultz L.D., Swift M. Evaluation of wasted mouse fibroblasts and SV40-transformed human fibroblasts as models of ataxia telangiectasia in vitro. Mutation Redsearch 1984; 140: 219–222
  • Seabright M. A rapid banding technique for human chromosomes. Lancet 1971; ii: 971–972
  • Taylor A.M.R., Harnden D.G., Arlett C.F., Harcourt S.A., Lehmann A.R., Stevens S., Bridges B.A. Ataxia-telangiectasia: a human mutation with abnormal radiation sensitivity. Nature 1975; 258: 427–429
  • Ziv Y., Jaspers N.G.J., Etkin S., Danieli T., Trakhtenbrot L., Amiel A., Ravia Y., Shiloh Y. Cellular and molecular characteristics of an immortalized ataxia-telangiectasia (group AB) cell line. Cancer Research 1989; 49: 2495–2501

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