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Original Article

Kinetics of Chromosome Lesion Repair in Synchronized Quiescent and Proliferating CHO Cells

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Pages 1009-1023 | Received 03 Jan 1990, Accepted 15 May 1990, Published online: 03 Jul 2009

References

  • Bedford J.S., Cornforth M.N. Relationship between the recovery from sublethal X-ray damage and the rejoining of chromosome breaks in normal human fibroblasts. Radiation Research 1987; 111: 406–423
  • Bryant P.E. Enzymatic restriction of mammalian cell DNA using Pvu II and Bam H1: evidence for the double-strand break origin of chromosomal aberrations. International Journal of Radiation Biology 1984; 46: 57–65
  • Bryant P.E. Use of restriction endonucleases to study relationships between DNA double-strand breaks, chromosomal aberrations and other end-points in mammalian cells. International Journal of Radiation Biology 1988; 54: 869–890
  • Bryant P.E., Birch D.A., Jeggo P.A. High chromosomal sensitivity of Chinese hamster xrs-5 cells to restriction endonuclease included DNA double-strand breaks. International Journal of Radiation Biology 1987; 50: 537–554
  • Catcheside D.G., Lea D.E., Thoday J.M. The production of chromosome structural changes in Tradescantia microspores in relation to dosage, intensity and temperature. Journal of Genetics 1946; 47: 137–157
  • Chadwick K.H., Leenhouts H.P. The Molecular Theory of Radiation Biology. Springer Verlag, Berlin and Heidelberg 1981
  • Dikomey E. Induction and repair of DNA strand breaks in X-irradiated proliferating and quiescent CHO cells. International Journal of Radiation Biology 1990; 57: 1169–1182
  • Dikomey E., Franzke J. DNA repair kinetics after exposure to X-irradiation and to internal β-rays in CHO cells. Radiation and Environmental Biophysics 1986; 25: 189–194
  • Giaccia A., Weinstein R., Hu J., Stamato T.D. Cell cycle-dependent repair of double-strand DNA breaks in a γ-ray-sensitive Chinese hamster cell. Somatic Cell and Molecular Genetics 1985; 11: 485–491
  • Gerweck L.E., Epp E.R., Michaels H.B., Ling C.C., Peterson E.C. Repair of sublethal damage in mammalian cells irradiated at ultrahigh dose rates. Radiation Research 1979; 77: 156–169
  • Iliakis G. Radiation-induced potentially lethal damage: DNA lesions susceptible to fixation. International Journal of Radiation Biology 1988; 53: 541–584
  • Iliakis G., Seaner R. Differences in inhibition by beta-arabino-furanosyladenine (ara A) of radiation induced DNA damage repair in exponentially growing and plateau-phase CHO-cells. Radiation and Environmental Biophysics 1988; 27: 295–305
  • Iliakis G., Pantelias G.E., Okayasu R., Seaner R. 125IdUrd-induced chromosome fragments, assayed by premature chromosome condensation, and DNA double-strand breaks have similar repair kinetics G1-phase CHO-cells. International Journal of Radiation Biology 1987; 52: 705–722
  • Iliakis G., Pantelias G.E., Seaner R. Effect of arabino-furanosyladenine on radiation-induced chromosome damage in plateau-phase CHO cells measured by premature chromosome condensation: Implications for repair and fixation of α-PLD. Radiation Research 1988; 114: 361–378
  • Kemp L.M., Sedgewick S.G., Jeggo P.A. X-ray sensitive mutants of Chinese hamster ovary cells defective in double-strand break rejoining. Mutation Research 1984; 132: 189–196
  • Kolin-Gerresheimer J., Bauchinger M. Dependence of the frequency of harlequin-stained cells on BrdUrd-concentrations in human lymphocyte cultures. Mutation Research 1981; 91: 251–254
  • Lea D.E. Actions of Radiations on Living Cells. Cambridge University Press, Cambridge 1946
  • Lopez B., Coppey J. Promotion of double-strand break repair by human nuclear extracts preferentially involves recombination with intact homologous DNA. Nucleic Acids Research 1987; 15: 6813–6826
  • Natarajan A.T., Obe G. Molecular mechanisms involved in the production of chromosomal aberrations. I. Utilization of Neurospora endonuclease in G2 stage of the cell cycle. Mutation Research 1978; 52: 137–149
  • Natarajan A.T., Zwanenburg T.S.B. Mechanisms for chromosomal aberrations in mammalian cells. Mutation Research 1982; 95: 1–6
  • Natarajan A.T., Obe G. Molecular mechanisms involved in the production of chromosomal aberrations. III. Restriction endonucleases. Chromosoma (Berlin) 1984; 90: 120–127
  • Ostashevsky J.Y. A model relating cell survival to DNA fragment loss and unrepaired double-strand breaks. Radiation Research 1989; 118: 437–466
  • Pantelias G.E., Maillie H.D. The measurement of immediate and persistent radiation-induced chromosome damage in rodent primary cells using premature chromosome condensation. Health Physics 1985; 49: 425–433
  • Pantelias G.E., Wolff S. Cytosine arabinoside is a potent clastogen and does not affect the repair of X-ray-induced chromosome fragments in unstimulated human lymphocytes. Mutation Research 1985; 151: 65–72
  • Preston R.J. Radiation damage to DNA and its repair in the formation of chromosome aberrations. Radiation-Induced Chromosome Damage in Man, T. Ishihara, M.S. Sasaki. A. R. Liss, New York 1983; 111–125
  • Radford Y.R. Effect of cell-cycle position and dose on the kinetics of DNA double-strand breakage repair in X-irradiated Chinese hamster cells. International Journal of Radiation Biology 1987; 52: 555–563
  • Raju M.M., Frank J.P., Bain E., Trujillo T.T., Tobey R.A. Repair of potentially lethal damage in Chinese hamster cells after X- and α-irradiation. Radiation Research 1977; 71: 614–621
  • Rao S.B., Hopwood L.E. Modification of mutation frequency in plateau-phase Chinese hamster ovary cells exposed to gamma radiation during recovery from potentially lethal damage. International Journal of Radiation Biology 1982; 42: 501–508
  • Rowley R., Kort L. The effect of modulators of radiation-induced G2 arrest on the repair of radiation-induced DNA damage detectable by neutral filter elution. International Journal of Radiation Biology 1988; 54: 749–759
  • Schmid E., Bauchinger M., Mergenthaler W. Analysis of the time relationship of X-ray induced primary breaks in the formation of dicentric chromosomes. International Journal of Radiation Biology 1976; 30: 339–346
  • Tobias C.A. The repair-misrepair model in radiobiology. Comparison to other models. Radiation Research 1985; 104: 77–95
  • Van Ankeren S.C., Murray D., Meyn R.E. Induction and rejoining of γ-rayinduced DNA single- and double-strand breaks in Chinese hamster AA8 cells and in two radiosensitive clones. Radiation Research 1988; 116: 511–525
  • Van der Schans G.P., Paterson M.C., Cross W.G. DNA strand break and rejoining in cultured human fibroblasts exposed to fast neutrons or gamma rays. International Journal of Radiation Biology 1983; 44: 75–85
  • Virsik R.P., Harder D. Recovery kinetics of radiation-induced chromosome aberrations in human G0 lymphocytes. Radiation and Environmental Biophysics 1980; 18: 221–238
  • Virsik-Peuckert R.P., Harder D. Kinetics of the effect of ara C on chromosome aberration yield in irradiated human lymphocytes. International Journal of Radiation Biology 1986a; 49: 103–108
  • Virsik-Peukert R.P., Harder D. Temperature and the formation of radiation-induced chromosome aberrations. II. The temperature dependence of lesion repair and lesion interaction. International Journal of Radiation Biology 1986b; 49: 673–681
  • Weibezahn K.F., Coquerelle T. Radiation induced DNA double strand breaks are rejoined by ligation and recombination processes. Nucleic Acids Research 1981; 9: 3139–3150
  • Weibezahn K.F., Lohrer H., Herrlich P. Double-strand break repair and G2 block in Chinese hamster ovary cells and their radiosensitive mutants. Mutation Research 1985; 145: 177–183
  • Wheeler K.T., Nelson G.B., Terrell K.E., Wallen C.A. Regulation of DNA repair kinetics in proliferative and quiescent tumour cells. International Journal of Radiation Biology 1988; 54: 245–255
  • Winans L.F., Dewey W.C., Dettor C.M. Repair of sublethal and potentially lethal X-ray damage in synchronous Chinese hamster cells. Radiation Research 1972; 52: 333–351
  • Winegar R.A., Preston R.Y. The induction of chromosome aberrations by restriction endonucleases that produce blunt-end or cohesive-end double-strand breaks. Mutation Research 1988; 197: 141–149
  • Wlodek D., Hittelman W.N. The relationship of DNA and chromosome damage to survival of synchronized X-irradiated L51784 cells. Radiation Research 1988; 115: 566–575
  • Zhang S., Dong W. Chromosomal aberrations induced by the restriction endonucleases Eco R I, Pst I, Sal I and Bam HI in CHO-cells. Mutation Research 1987; 180: 109–114

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