DNA Radiolysis by Fast Neutrons

References

• Achey Ph., Duryea H. Production of DNA strand breaks by the hydroxyl radicals. International Journal of Radiation Biology 1974; 25: 595–601
   Web of Science ®Google Scholar
• Adinarayama M., Bothe E., Schulte-Frohlinde D. Hydroxyl radicalinduced strand break formation in single-stranded polynucleotides and singlestranded DNA in aqueus solution as measured by light scattering and by conductivity. International Journal of Radiation Biology 1988; 54: 723–737
   PubMedGoogle Scholar
• Barendsen G.W. Responses of cultured cells, tumors and normal tissues to radiations of different linear energy transfer. Current Topics of Radiation Research 1968; IV: 293–356
   Google Scholar
• Barendsen G.W., Koot C.J., Van Kersen G.R. The effect of oxygen on impairment of the proliferative capacity of human cells in culture by ionizing radiations of different LET. International Journal of Radiation Biology 1966; 10: 317–327
   Web of Science ®Google Scholar
• Belli M., Cherubini R., Galeazzi G., Mazzucato S., Moschini G., Sapora O., Simone G., Tabocchini M.A. Proton irradiation facility for radiobiological studies at a 7 MeV Van der Graaf accelerator. Nuclear Instruments and Methods in Physics Research 1987; A256: 576–580
   Google Scholar
• Belli M., Cherubini R., Finotto S., Moschini G., Sapora O., Simone G., Tabocchini M.A. RBE-LET relationship for the survival of V79 cells irradiated with low energy protons. International Journal of Radiation Biology 1989; 55: 93–104
   PubMed Web of Science ®Google Scholar
• Billen D. The role of hydroxyl radical scavenger in preventing DNA strand breaks induced by X irradiation of toluene-treated E. coli. Radiation Research 1984; 97: 626–629
   PubMed Web of Science ®Google Scholar
• Blakely E., Tobias C.A., Yang T.C.H., Smith K.C., Lyman J.T. Inactivation of human kidney cells by high-energy monoenergetic heavy-ion beams. Radiation Research 1979; 80: 122–160
   PubMed Web of Science ®Google Scholar
• Blazek E.R., Peak M.J. The role of hydroxyl radical quenching in the protection by acetate and ethylene-diaminetetraacetate of supercoiled plasmid DNA from ionizing radiation-induced strand breakage. International Journal of Radiation Biology 1988; 53: 237–247
   Web of Science ®Google Scholar
• Blocher D. DNA double strand break repair determines the RBE of alpha-particles. International Journal of Radiation Biology 1988; 54: 761–771
   PubMed Web of Science ®Google Scholar
• Blok J., Loman H. The effects of gamma radiation in DNA. Current Topics in Radiation Research Quarterly 1973; 9: 165–245
   PubMedGoogle Scholar
• Blok J., Luthjens L.H., Roos A.L.M. The radiosensitivity of bacteriophage DNA in aqueous solution. Radiation Research 1967; 30: 468–482
   PubMed Web of Science ®Google Scholar
• Chaterjee A., Magee J.L. Theoretical investigation of the production of strand breaks in DNA by water radicals. Radiation Protection Dosimetry 1985; 13: 137–140
   Google Scholar
• Chaterjee A., Magee J.L. Radiation Chemistry, Farhataziz, M.A.J. Rodgers. VCH Publishers, New York 1987; 173–199, In
   Google Scholar
• Christensen R.C., Tobias C.A., Taylor W.D. Heavy-ion-induced single-and double-strand breaks in φ-174 replicative form DNA. International Journal of Radiation Biology 1972; 22: 457–477
   Web of Science ®Google Scholar
• Coogan T.P., Rosenblum I.Y. DNA double-strand damage and repair following gamma irradiation in isolated spermatogenic cells. Mutation Research 1988; 194: 183–191
   PubMedGoogle Scholar
• Cowan R., Collis C.M., Grigg G.W. Breakage of double-stranded DNA due to single-stranded nicking. Journal of Theoretical Biology 1987; 127: 229–245
   PubMed Web of Science ®Google Scholar
• Ekert B., Sabattier R., Pironin M. Unusual alkaline elution pattern induced in mammalian cell DNA by fast neutrons p(34)+Be. International Journal of Radiation Biology 1988; 54: 39–53
   PubMed Web of Science ®Google Scholar
• Ferradini C., Pucheault J. Biologie de l'Action des Rayonnements Ionisants. Masson, Paris 1983; 11–12, 25–82.
   Google Scholar
• Fox J.C., McNally N.J. Cell survival and DNA double-strand break repair following X-ray or neutron irradiation of V79 cells. International Journal of Radiation Biology 1988; 54: 1021–1030
   PubMed Web of Science ®Google Scholar
• Frankenberg D., Frankenberg-Schwager M., Blocker D., Harbich R. Evidence for DNA double-strand breaks as the critical lesions in yeast cells irradiated with sparsely or densely ionizing radiation under oxic and anoxic conditions. Radiation Research 1981; 88: 524–532
   PubMed Web of Science ®Google Scholar
• Frankenberg-Schwager M. Review of repair kinetics for DNA damages induced in eukaryotic cells in vitro by ionizing radiations. Radiotherapy and Oncology 1989; 14: 307–320
   PubMed Web of Science ®Google Scholar
• Frankenberg-Schwager M., Frankenberg D., Blocker D., Adamczyk C. The linear relationship between DNA double strand breaks and radiation dose (30 MeV electrons) is converted into quadratic function by cellular repair. International Journal of Radiation Biology 1980; 37: 207–212
   Web of Science ®Google Scholar
• Frankenberg-Schwager M., Frankenberg D., Harbich R. Repair of DNA double strand breaks as a determinant of RBE of alpha particles. British Journal of Cancer 1984; 49(VI)169–173
   Google Scholar
• Freifelder D., Trumbo B. Matching of single-strand breaks to form doublestranded breaks in DNA. Biolymers 1969; 7: 681–693
   Web of Science ®Google Scholar
• Furuno I., Yada T., Matsudaira H., Maruyama T. Induction and repair of DNA strand breaks in cultured mammalian cells following fast neutron irradiation. International Journal of Radiation Biology 1979; 36: 639–648
   Web of Science ®Google Scholar
• Goodhead D.T., Nikjoo H. Track structure analysis of ultrasoft X-rays compared to high- and low-LET radiations. International Journal of Radiation Biology 1989; 55: 514–529
   Web of Science ®Google Scholar
• Griffin T.W., Wambersie A., Laramore G., Castro J. High LET: heavy particle trials. International Journal of Radiation Oncology, Biology and Physics 1988; 14: S83–S92
   Google Scholar
• Hagen U. Bestimmung von einzel- und doppelbrüchen in bestrahlter desoxyribonucleinsäure durch die moleculargewichtsverteilung. Biochimica et Biophysica Acta 1967; 134: 45–58
   Web of Science ®Google Scholar
• Hall E.J., Roizin-Towle L., Theus R.B., August L. Radiobiological properties of high energy cyclotron produced neutrons used in radiotherapy. Radiology 1975; 117: 173–178
   PubMed Web of Science ®Google Scholar
• Hempel K., Mildenberger E. Determination of G-values for single and double strand break induction in plasmic DNA using agarose gel electrophoresis and a curvefitting procedure. International Journal of Radiation Biology 1987; 52: 125–138
   Web of Science ®Google Scholar
• ICRU Publications. Microdosimetry, International Commission on Radiation Units and Measurements Report 36. ICRU Publication, BethesdaU.S.A. 1983; 91–91
   Google Scholar
• Kupperman A. Diffusion kinetics in radiation chemistry: an assessment. Physical Mechanisms in Radiation Biology, R.D. Cooper, R.W. Wood. Springfield, Virginia 1974; 155–183
   Google Scholar
• Maniatis T.C., Fritsch E.F., Sambrook J. Molecular Cloning. A Laboratory Manual. Cold Spring Harbor Laboratory. 1982; 88–96
   Google Scholar
• Neary G.J., Simpson-Gildemeister V.F.W., Peacocke A.R. The influence of radiation quality and oxygen on strand breakage in dry DNA. International Journal of Radiation Biology 1970; 18: 25–40
   Web of Science ®Google Scholar
• Onal A.M., Lemaire D.G.E., Bothe E., Schulte-Frohlinde D. Gammaradiolysis of poly(A) in aqueous solution: efficiency of strand break formation by primary water radicals. International Journal of Radiation Biology 1988; 53: 787–796
   Web of Science ®Google Scholar
• Peak M.J., Peak J.C., Carnes B.A., Chang Liu C.H., Hill C.K. DNA damage and repair in rodent and human cells after exposure to Janus fission spectrum neutrons: a minor fraction of single strand breaks as revealed by alkaline elution is refractory to repair. International Journal of Radiation Biology 1989; 55: 761–772
   PubMed Web of Science ®Google Scholar
• Perris A., Pialoglou P., Katsanos A.A., Sideris E.G. Biological effectiveness of low energy protons. I. Survival of Chines hamster cells. International Journal of Radiation Biology 1986; 50: 1093–1101
   Web of Science ®Google Scholar
• Radford I.R. The level of induced DNA double strand breakage correlates with cell killing after X-irradiation. International Journal of Radiation Biology 1985; 48: 45–54
   Web of Science ®Google Scholar
• Radford I.R. The dose-response for low-LET radiation-induced DNA doublestrand breakage: methods of measurement and implications for radiation action models. International Journal of Radiation Biology 1988; 54: 1–11
   PubMed Web of Science ®Google Scholar
• Radford I.R., Hodgson G.S., Matthews J.P. Critical DNA target size model of ionizing radiation-induced mammalian cell death. International Journal of Radiation Biology 1988; 54: 63–79
   PubMed Web of Science ®Google Scholar
• Ritter M.A., Cleaver J.E., Tobias C.A. High-LET radiation induce a large proportion of non-rejoining DNA breaks. Nature 1977; 266: 653–655
   PubMed Web of Science ®Google Scholar
• Roots R., Okada S. Protection of DNA molecules of cultured mammalian cells from radiation-induced single-strand scissions by various alcohols and SH compounds. International Journal of Radiation Biology 1972; 21: 329–342
   Web of Science ®Google Scholar
• Roots R., Kraft G., Gosschalk E. The formation of radiation induced DNA breaks: the ratio of double-strand breaks to single-strand breaks. International Journal of Radiation Oncology, Biology and Physics 1985; 11: 259–265
   PubMed Web of Science ®Google Scholar
• Sakai K., Susuki S., Nakamura N., Okada S. Induction and subsequent repair of DNA damage by fast neutrons in cultured mammalian cells. Radiation Research 1987; 110: 311–320
   PubMed Web of Science ®Google Scholar
• Sanner T., Pihl A. Significance and mechanism of the indirect effect in bacterial cells. The relative protective effect of added compounds in E. coli B1 irradiated in liquid and frozen suspension. Radiation Research 1969; 37: 216–227
   PubMed Web of Science ®Google Scholar
• Siddiqi M.A., Bothe E. Single- and double-strand break formation in DNA irradiated in aqueous solution: dependence on dose and OH radical scavenger concentration. Radiation Research 1987; 112: 449–463
   PubMed Web of Science ®Google Scholar
• Skov K.A. The contribution of hydroxyl radical to radiosensitization: a study of DNA damage. Radiation Research 1984; 99: 502–510
   PubMed Web of Science ®Google Scholar
• Tubiana M., Dutreix J., Dutreix A., Jockey P. Bases Physiques de la Radiotherapie et de la Radiobiologie. Masson & Cie, Paris 1963; 143–157
   Google Scholar
• Tubiana M., Dutreix J., Wambersie A. Radiobiologie. Hermann, Paris 1986; 219–250
   Google Scholar
• van der Schans G.P., Paterson M.C., Cross W.G. DNA strand breaks and rejoining in cultured human fibroblasts exposed to fast neutrons or gamma rays. International Journal of Radiation Biology 1983; 44: 75–85
   Web of Science ®Google Scholar
• van Rijn K., Mayer T., Blok J., Verberne J.B., Loman H. Reaction rate of OH radicals with φ 174 DNA: influence of salt and scavenger. International Journal of Radiation Biology 1985; 47: 309–317
   Web of Science ®Google Scholar
• van Touw J.H., Verberne J.B., Retel J., Loman H. Radiation-induced strand breaks in φ 174 replicative form DNA: an improved experimental and theoretical approach. International Journal of Radiation Biology 1985; 48: 567–578
   Web of Science ®Google Scholar
• von Sonntag C. The Chemical Basis of Radiation Biology. Taylor & Francis, London 1987; 31–56
   Google Scholar
• von Sonntag C., Hagen U., Schön-Bopp A., Schulte-Frohlinde D. Radiation induced strand breaks in DNA. Chemical and enzymatic analysis of end groups and mechanistic aspects. Advances in Radiation Biology 1981; 9: 109–245
   Google Scholar
• Wambersie A., Barendsen G.W., Breteau N. Overview and prospects of the application of fast neutrons in cancer therapy. Journal Européen de Radiotherapie, Oncologie, Radiophysique 1984; 5: 248–264
   Google Scholar
• Watt D.E. Absolute biological effectiveness of neutrons and photons. Radiation Protection Dosimetry 1988; 23: 63–67
   Web of Science ®Google Scholar
• Wilson W.E., Paretzke H.G. Calculation of distribution for energy imparted and ionization by fast protons in nanometer sites. Radiation Research 1981; 87: 521–537
   Web of Science ®Google Scholar