Radiation-induced Heart Disease: Review of Experimental Data on Dose Reponse and Pathogenesis

References

• Adler K., Fröhlich D., Gottschild D., Neumann G., Neumeister K. Myokardszintigraphische Untersuchungen mit 201Thallium nach Strahlentherapie im Thoraxbereich. Zeitschrift für Klinische Medizin 1987; 42: 2343–2346
   Google Scholar
• Annest L.S., Anderson R.P., Li W., Hafermann M.D. Coronary artery disease following mediastinal radiation therapy. Journal of Thoracic and Cardiovascular Surgery 1983; 85: 257–263
   PubMedGoogle Scholar
• Applefeld M.M., Wiernik P.H. Cardiac disease after radiation therapy for Hodgkin's disease: analysis of 48 patients. American Journal of Cardiology 1983; 51: 1679–1681
   PubMed Web of Science ®Google Scholar
• Barnes M., Pass H., DeLuc A., Tochner Z., Potter D., Terrill R., Sindelar W.F., Kinsella T.J. Response of the mediastinal and thoracic viscera of the dog to intraoperative radiation therapy (IORT). International Journal of Radiation Oncology, Biology and Physics 1987; 13: 371–378
   PubMedGoogle Scholar
• Blitzer P.H., Hutchison G.B., Salenius S.A., Hsieh C.-C. Increased incidence of cardiac deaths long after irradiation of the heart. Radiation Research Society 35th Annual Meeting February, 1987
   Google Scholar
• Boivin J.F., Hutchison G.B. Coronary artery mortality after irradiation for Hodgkin's disease. Cancer 1982; 49: 2470–2475
   PubMed Web of Science ®Google Scholar
• Brosius F.C., Waller B.F., Roberts W.L. Analysis of 16 young (aged 15–33 years) necropsy patients who received over 3,500 rads to the heart. American Journal of Medicine 1981; 70: 519–530
   PubMed Web of Science ®Google Scholar
• Brown J.M., Fajardo L.F., Stewart J.R. Mural thombosis of the heart induced by radiation. Archives of Pathology 1973; 96: 1–4
   PubMedGoogle Scholar
• Burns R.J., Bar-Shlomo B.-Z., Druck M.N., Herman J.G., Gilbert B.W., Perrault D.J., McLaughlin P.R. Detection of radiation cardiomyopathy by gated radionuclide angiography. American Journal of Medicine 1983; 74: 297–302
   PubMed Web of Science ®Google Scholar
• Byhardt R., Brace K., Ruckdeschel J., Chang P., Martin R., Wiernik P. Dose and treatment factors in radiation-related pericardial effusion associated with the mantle technique for Hodgkin's disease. Cancer 1975; 35: 795–802
   PubMed Web of Science ®Google Scholar
• Carmel R.J., Kaplan H.S. Mantle irradiation in Hodgkin's disease: an analysis of technique, tumour eradication and complications. Cancer 1976; 37: 2813–2825
   PubMed Web of Science ®Google Scholar
• Catteral M., Evans W. Myocardial injury from therapeutic irradiation. British Heart Journal 1960; 22: 168–174
   PubMedGoogle Scholar
• Cilliers G.D., Harper I.S., Lochner A. Radiation-induced changes in the ultrastructure and mechanical function of the rat heart. Radiotherapy and Oncology 1989; 16: 311–326
   PubMed Web of Science ®Google Scholar
• Cohn K.E., Stewart J.R., Fajardo L.F., Hancock E.W. Heart disease following radiation. Medicine 1967; 46: 281–298
   PubMed Web of Science ®Google Scholar
• Cosset J.M., Henry-Amar M., Girinski T., Malaise E., Dupouy N., Dutreix J. Late toxicity of radiotherapy in Hodgkin's disease: The role of fraction size. Acta Oncologica 1988; 27: 123–129
   PubMed Web of Science ®Google Scholar
• Douglas B.G., Fowler J.F. The effect of multiple small doses of X-rays on skin reactions in the mouse and a basic interpretation. Radiation Research 1976; 66: 401–426
   PubMed Web of Science ®Google Scholar
• Down J.D. The nature and relevance of late lung pathology following localised irradiation of the thorax in mide and rats. British Journal of Cancer 1986; 53(Supplement VII)330–332
   Google Scholar
• Engerman R.L., Pfaffenbach D., Davis M.D. Cell turnover in capillaries. Laboratory Investigation 1967; 17: 738–743
   PubMed Web of Science ®Google Scholar
• Fajardo L.F., Stewart J.R., Cohn K.E. Morphology of radiation induced heart disease. Archives of Pathology 1968; 86: 512–519
   PubMedGoogle Scholar
• Fajardo L.F., Stewart J.R. Experimental radiation-induced heart disease. American Journal of Pathology 1970; 59: 299–316
   PubMed Web of Science ®Google Scholar
• Fajardo L.F., Stewart J.R. Capillary injury preceding radiation-induced myocardial fibrosis. Radiology 1971; 101: 429–433
   PubMed Web of Science ®Google Scholar
• Fajardo L.F., Stewart J.R. Pathogenesis of radiation-induced myocardial fibrosis. Laboratory Investigation 1973; 29: 244–257
   PubMed Web of Science ®Google Scholar
• Gavin P.R., Gillette E.L. Radiation response of the canine cardiovascular system. Radiation Research 1982; 90: 489–500
   PubMed Web of Science ®Google Scholar
• Geist B.J., Trott K.-R., Lauk S. Physiologic consequences of local heart irradiation in rats. International Journal of Radiation Oncology, Biology and Physics 1990; 18: 1107–1113
   PubMedGoogle Scholar
• Gillette E.L., McChesney S.L., Hoopes P.J. Isoeffect curves for radiation-induced cardiomyopathy in the dog. International Journal of Radiation Oncology, Biology and Physics 1985; 11: 2091–2097
   PubMedGoogle Scholar
• Gomez G.A., Park J.J., Panahon A.M., Parthasarathy K.L., Pearce J., Reese P., Bakshi S., Henderson E.S. Heart size and function after radiation therapy to the mediastinum in patients with Hodgkin's disease. Cancer Treatment Report 1983; 67: 1099–1103
   PubMedGoogle Scholar
• Gottdiener J.S., Katin M.J., Borer J.S., Bacharach S.L., Green M.V. Late cardiac effects of therapeutic mediastinal irradiation. Assessment by echocardiography and radionuclide angiography. New England Journal of Medicine 1983; 308: 569–588
   PubMed Web of Science ®Google Scholar
• Greenwood R.D., Rosenthal A., Cassady R., Jaffe N., Nadas A.S. Constrictive pericarditis in childhood due to mediastinal irradiation. Circulation 1974; 50: 1033–1039
   PubMed Web of Science ®Google Scholar
• Haas J.M. Symptomatic constrictive pericarditis developing 45 years after radiation therapy to the mediastinum. American Heart Journal 1969; 77: 89–95
   PubMedGoogle Scholar
• Hobson B., Denekamp J. Endothelial proliferation in tumours and normal tissues: continuous labelling studies. British Journal of Cancer 1984; 49: 405–413
   PubMed Web of Science ®Google Scholar
• Host H., Brennhovd I.O., Loeb M. Postoperative radiotherapy in breast cancer—long-term results from the Oslo study. International Journal of Radiation Oncology, Biology and Physics 1986; 12: 727–732
   PubMed Web of Science ®Google Scholar
• Ikäheimo M.J., Niemelä M.M., Linnaluoto M.M., Jakobsson M.J.T., Takkunen J.T., Taskinen P.J. Early cardiac changes related to radiation therapy. American Journal of Cardiology 1985; 56: 943–946
   PubMed Web of Science ®Google Scholar
• Khan M.Y. Radiation-induced cardiomyopathy. I. An electron microscopic study of cardiac muscle cells. American Journal of Pathology 1973; 73: 131–146
   PubMed Web of Science ®Google Scholar
• Khan M.Y., Ohanian M. Radiation-induced cardiomyopathy. II. An electron microscopic study of myocardial microvasculature. American Journal of Pathology 1974; 74: 125–136
   PubMed Web of Science ®Google Scholar
• Lagrange J.-L., Darcourt J., Benoliel J., Bensadoun R.-J., Mignedo O. Acute cardiac effects of mediastinal irradiation: Asessment by radionuclide angiography. International Journal of Radiation Oncology, Biology and Physics 1991, (Accepted for publication)
   PubMedGoogle Scholar
• Lauk S. Strain differences in the radiation response of the rat heart. Radiotherapy and Oncology 1986; 5: 333–335
   PubMedGoogle Scholar
• Lauk S. Endothelial alkaline phosphatase activity loss as an early stage in the development of radiation-induced heart disease in rats. Radiation Research 1987; 110: 118–128
   PubMed Web of Science ®Google Scholar
• Lauk S., Trott K.-R. Endothelial proliferation in the rat heart following local heart irradiation. International Journal of Radiation Biology 1990; 57: 1017–1030
   PubMed Web of Science ®Google Scholar
• Lauk S., Zimmer H.G. Vergleich von funktionellen und morphologischen Untersuchungsergebnissen am lokal bestrahlten Rattenherzen, Jahresbericht Experimentelle Tumortherapie. GSF-Bericht 1984; 31/85: 73–76
   Google Scholar
• Lauk S., Böhm M., Feiler G., Geist B.J., Erdmann E. Increased number of cardiac adrenergic receptors following local heart irradiation. Radiation Research 1989; 119: 157–165
   PubMed Web of Science ®Google Scholar
• Lauk S., Kiszel Z., Buschmann J., Trott K.-R. Radiation induced heart disease in rats. International Journal of Radiation Oncology, Biology and Physics 1985; 11: 801–808
   PubMed Web of Science ®Google Scholar
• Lauk S., Rüth S., Trott K.-R. The effects of dose-fractionation on radiation-induced heart disease in rats. Radiotherapy and Oncology 1987; 8: 363–367
   PubMed Web of Science ®Google Scholar
• Macleod C.A., Schwartz H., Linton D.B. Constrictive pericarditis following irradiation therapy. Journal of the American Medical Association 1969; 24: 2281–2282
   Google Scholar
• Martin R.G., Ruckdeschel J.C., Chang C., Byhardt R., Bouchard R.J., Wiernik P.H. Radiation-related pericarditis. American Journal of Cardiology 1975; 35: 216–220
   PubMed Web of Science ®Google Scholar
• McChesney S.L., Gillette E.L., Orton E.C. Canine cardiomyopathy after whole heart and partial lung irradiation. International Journal of Radiation Oncology, Biology and Physics 1988a; 14: 1169–1174
   PubMed Web of Science ®Google Scholar
• McChesney S.L., Gillette E.L., Powers B.E. Radiation-induced cardiomyopathy in the dog. Radiation Research 1988b; 113: 120–132
   PubMedGoogle Scholar
• McChesney S.L., Gillette S., Powers B.E., Orton E.C., Gillette E.L. Early radiation response of the canine heart and lung. Radiation Research 1991; 125: 34–41
   PubMedGoogle Scholar
• Morgan G.W., Freeman A.P., McLean R.G., Jarvie B.H., Giles R.W. Late cardiac, thyroid and pulmonary sequelae of mantle radiotherapy for Hodgkin's disease. International Journal of Radiation Oncology, Biology and Physics 1985; 11: 1925–1931
   PubMed Web of Science ®Google Scholar
• Morgenroth K., Junge-Hülsing G., Hauss W.H. Über Veränderungen am Rattenherzen nach gezielter Röntgenbestrahlung. Strahlentherapie 1967; 133: 610–620
   PubMedGoogle Scholar
• Murray J.C., Parkins C.S. Collagen synthesis in CBA mouse heart after total thoracic irradiation. Radiotherapy Oncology 1988; 13: 137–143
   PubMed Web of Science ®Google Scholar
• Nakatani T., Shinohara H., Fukuo Y., Morisawa S., Matsuda T. Pericardium of rodents: pores connect the pericardial and pleural cavities. Anatomical Records 1988; 220: 132–137
   PubMedGoogle Scholar
• Phillips S.J., Reid A.J., Rugh R. Electrocardiographic and pathologic changes after X-irradiation in dogs. American Heart Journal 1964; 68: 524–533
   PubMedGoogle Scholar
• Pierce R.H., Haferman M.D., Kagan A.R. Changes in the transverse cardiac diameter following irradiation for Hodgkin's disease. Radiology 1969; 93: 619–624
   PubMed Web of Science ®Google Scholar
• Savage D.E., Constine L.S., Schwartz R.G., Rubin P. Radiation effects on left-ventricular function and myocardial perfusion in long term survivors of Hodgkin's disease. International Journal of Radiation Oncology, Biology and Physics 1990; 19: 721–727
   PubMed Web of Science ®Google Scholar
• Schultz-Hector S. Heart. Radiopathology of Organs and Tissues, E. Scherer, Ch. Streffer, K.R. Trott. Springer, Heidelberg 1991; 347–368
   Google Scholar
• Schultz-Hector S., Böhm M., Blöchel A., Dominiak P., Erdmann E., Müller-Schauenburg W., Weber A. Radiation-induced heart disease: Morphology, changes in catecholamine synthesis and content, β-adrenoceptor density and hemodynamic function in an experimental model. Radiation Research. 1991a, (Submitted)
   Google Scholar
• Schultz-Hector S., Sund M., Thames H.D. Fractionation response and repair kinetics of radiation-induced heart failure in the rat. Radiotherapy and Oncology 1991b, (Submitted)
   Google Scholar
• Stewart J.R., Fajardo L.F. Radiation-induced heart disease. Clinical and experimental aspects. Radiologic Clinics of North America 1971a; 9: 511–531
   PubMed Web of Science ®Google Scholar
• Stewart J.R., Fajardo L.F. Dose response in human and experimental radiation-induced heart disease. Radiology 1971b; 99: 403–408
   PubMed Web of Science ®Google Scholar
• Stewart J.R., Fajardo L.F., Cohn K.E., Page V. Experimental radiation-induced heart disease in rabbits. Radiology, 91: 814–817
   PubMedGoogle Scholar
• Stone H.L., Bishop V.S., Guyton A.C. Progressive changes in cardiovascular function after unilateral heart irradiation. American Journal of Physiology 1964; 206: 289–293
   PubMed Web of Science ®Google Scholar
• Strender L.E., Lindahl J., Larsson L.E. Incidence of heart disease and functional significance of changes in electrocardiogram 10 years after radiotherapy for breast cancer. Cancer 1986; 57: 929–934
   PubMed Web of Science ®Google Scholar
• Stryker J.A., Lee K.J., Abt A.B. The effects of X radiation on the canine heart. Radiation Research 1990; 82: 200–210
   Google Scholar
• Tarbell N.J., Thompson L., Mauch P. Thoracic irradiation in Hodgkin's disease: disease control and long-term complications. International Journal of Radiation Oncology, Biology and Physics 1990; 18: 275–281
   PubMed Web of Science ®Google Scholar
• Thames H.D., Rozell M.E., Tucker S.L., Ang K.K., Fisher D.R., Travis E.L. Direct analysis of quantal radiation response data. International Journal of Radiation Biology 1986; 49: 999–1009
   Web of Science ®Google Scholar
• Timmermans R., Gerber G.B. The effect of X-irradiation on cardiac beta-adrenergic receptors in the rabbit. Radiation Research 1984; 100: 510–518
   PubMed Web of Science ®Google Scholar
• Watchie J., Coleman N., Raffin T., Cox R., Rauibitschek A., Fahey T., Hoppe R., Venkessel A. Minimal long-term cardiopulmonary dysfunction following treatment for Hodgkin's disease. International Journal of Radiation Oncology, Biology and Physics 1987; 13: 517–524
   PubMed Web of Science ®Google Scholar
• Wheldon T.E., Jichalowski A.S., Kirk J. The effect of irradiation on function in self-renewing normal tissues with different proliferative organisation. British Journal of Radiology 1982; 55: 759–766
   PubMed Web of Science ®Google Scholar
• Wondergem J., van der Laarse A., van Ravels F.J.M., van Wermeskerken A.-M., Verhoeve H.R., de Graaf B.W., Leer J.W.H. In vitro assessment of cardiac performance after irradiation using an isolated working rat heart preparation. International Journal of Radiation Biology 1991; 59: 1053–1068
   PubMed Web of Science ®Google Scholar
• Yang V.V., Stearner S.P., Tyler S.A. Radiation-induced changes in the fine structure of the heart: comparison of fission neutrons and 60Co rays in the mouse. Radiation Research 1976; 67: 344–360
   PubMed Web of Science ®Google Scholar
• Yeung T.K., Hopewell J.W. Effects of single doses of irradiation on cardiac function in the rat. Radiotherapy and Oncology 1985; 3: 339–345
   PubMed Web of Science ®Google Scholar