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Original Article

Effect of TPA, Okadaic Acid and 1α,25-dihydroxyvitamin D3 on Neoplastic Transformation Induced by 60Co Gamma-rays or 252Cf Fission Neutrons in Balb/c 3T3 Cells

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Pages 253-262 | Received 20 Dec 1990, Accepted 21 Jul 1991, Published online: 03 Jul 2009

References

  • Bertram J.S. Effects of serum concentration on the expression of carcinogen-induced transformation in the C3H/10T1/2 CL8 cell line. Cancer Research 1977; 37: 514–523
  • Bialojan C., Takai A. Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Biochemical Journal 1988; 256: 283–290
  • Borek C., Troll W. Modifiers of free radicals inhibit in vitro the oncogenic actions of X-rays, bleomycin, and the tumour promoter 12-O-tetradecanoyl-phorbol 13-acetate. Proceedings of the National Academy of Science of the United States of America 1983; 80: 1304–1307
  • Chida K., Hashiba H., Fukushima M., Suda T., Kuroki T. Inhibition of tumour promotion in mouse skin by 1α,25-dihydroxyvitamin D3. Cancer Research 1985; 45: 5426–5430
  • Enomoto T., Yamasaki H. Phorbol ester-mediated inhibition of intercellular communication in BALB/c 3T3 cells: relationship to enhancement of cell transformation. Cancer Research 1985; 45: 2681–2688
  • Franceschi R.T. Interaction of the 1α,25-dihydroxyvitamin D3 receptor with RNA and synthetic polyribonucleotides. Proceedings of the National Academy of Science of the United States of America 1984; 81: 2337–2341
  • Goldstein B.D., Witz G., Amoruso M., Troll W. Protease inhibitors antagonize the activation of polymorphonuclear leukocyte oxygen consumption. Biochemical and Biophysical Research Communications 1979; 88: 854–860
  • Han A., Elkind M.M. Enhanced transformation of mouse 10T1/2 cells by 12-O-tetradecanoylphorbol-13-acetate following exposure to X-rays or to fission-spectrum neutrons. Cancer Research 1982; 42: 477–483
  • Hoshi M., Takeoka S., Tsujimura T., Kuroda T., Kawami M., Sawada S. Dosimetric evaluation of 252Cf beam for use in radiobiology studies at Hiroshima University. Physics in Medicine and Biology 1988; 33: 473–480
  • Huh N., Satoh M., Nose K., Abe E., Suda T., Rajewsky M.F., Kuroki T. 1α,25-dihydroxyvitamin D3 induces anchorage-independent growth and c-Kis-ras expression of BALB/3T3 and NIH/3T3 cells. Japanese Journal of Cancer Research (Gann) 1987; 78: 99–102
  • ICRU. The quality factor in radiation protection. ICRU Report 40. ICRU, Washington, DC 1986
  • Kakunaga T. A quantitative system for assay of malignant transformation by chemical carcinogens using a clone derived from Balb-3T3. International Journal of Cancer 1973; 12: 463–473
  • Katoh F., Fitzgerald D.J., Giroldi L., Fujiki H., Sugimura T., Yamasaki H. Okadaic acid and phorbol esters: comparative effects of these tumor promoters on cell transformation, intercellular communication and differentiation in vitro. Japanese Journal of Cancer Research 1990; 81: 590–597
  • Kennedy A.R., Mondal S., Heidelberger C., Little J.B. Enhancement of X-ray transformation by 12-O-tetradecanoyl-phorbol-13-acetate in a cloned line of C3H mouse embryo cells. Cancer Research 1978; 38: 439–443
  • Kennedy A.R., Murphy G., Little J.B. Effect of time and duration of exposure to 12-O-tetradecanoyl-phorbol-13-acetate on X-ray transformation of C3H 10T1/2 cells. Cancer Research 1980; 40: 1915–1920
  • Kennedy A.R., Troll W., Little J.B. Role of free radicals in the initiation and promotion of radiation transformation in vitro. Carcinogenesis 1984; 5: 1213–1218
  • Kennedy A.R. Effects of protease inhibitors and vitamin E in the prevention of cancer. Nutrients and Cancer Prevention. Humana Press, Clifton, New Jersey 1990; 79–98
  • Kuroki T., Sasaki K., Chida K., Abe E., Suda T. 1α,25-dihydroxyvitamin D3 markedly enhances chemically-induced transformation in BALB 3T3 cells. Japanese Journal of Cancer Research (Gann) 1983; 74: 611–614
  • Little J.B. Quantitative studies of radiation transformation with the A31-11 mouse BALB/3T3 cell line. Cancer Research 1979; 39: 1474–1480
  • MacKintosh C., Cohen P. Identification of high levels of type 1 and type 2A protein phosphatases in higher plants. Biochemical Journal 1989; 262: 335–339
  • Murray A.W., Fitzgerald D.J. Tumour promoters inhibit metabolic cooperation in cocultures of epidermal and 3T3 cells. Biochemical and Biophysical Research Communications 1979; 91: 395–401
  • Nagamine Y., Ziegler A. Okadaic acid induction of the urokinase-type plasminogen activator gene occurs independently of cAMP-dependent protein kinase and protein kinase C and is sensitive to protein synthesis inhibition. The European Molecular Biology Organization Journal 1991; 10: 117–122
  • Nishizuka Y. The role of protein kinase C in cell surface signal transduction and tumour promotion. Nature 1984; 308: 693–698
  • Reznikoff C.A., Bertram J.S., Brankow D.W., Heidelberger C. Quantitative and qualitative studies of chemical transformation of cloned C3H mouse embryo cells sensitive to postconfluence inhibition of cell division. Cancer Research 1973; 33: 3239–3249
  • Rivedal E., Mikalsen S.-O., Sanner T. The non-phorbol ester tumour promoter okadaic acid does not promote morphological transformation or inhibit junctional communication in hamster embryo cells. Biochemical and Biophysical Research Communications 1990; 167: 1302–1308
  • Sasaki K., Chida K., Hashiba H., Kamata N., Abe E., Suda T., Kuroki T. Enhancement by 1α,25-dihydroxyvitamin D3 of chemically induced transformation of BALB 3T3 cells without induction of ornithine decarboxylase or activation of protein kinase C. Cancer Research 1986; 46: 604–610
  • Sugamura M., Fujiki H., Suguri H., Yoshizawa S., Horita M., Nakayasu M., Ojika M., Wakamatsu K., Yamada K., Sugimura T. Okadaic acid: an additional non phorbol-12-tetradecanoate-13-acetate type tumour promoter. Proceedings of the National Academy of Science of the United States of America 1988; 85: 1768–1771
  • Woloschak G.E., Chang-Liu C.-M., Shearin-Jones P. Regulation of protein kinase C by ionizing radiation. Cancer Research 1990; 50: 3963–3967
  • Wood A.W., Chang R.L., Huang M.-T., Uskokovic M., Conney A.H. 1α,25-dihydroxyvitamin D3 inhibits phorbol ester-dependent chemical carcinogenesis in mouse skin. Biochemical and Biophysical Research Communications 1983; 116: 605–611
  • Yamasaki H., Enomoto K., Fitzgerald D.J., Mesnil M., Katoh F., Hollstein M. Role of intercellular communication in the control of critical gene expression during multistage carcinogenesis. Cell Differentiation, Genes and Cancer, IARC Scientific Publications No. 92. IARC, Lyon 1988; 57–75
  • Yotti L.P., Chang C.C., Trosko J.E. Elimination of metabolic cooperation in Chinese hamster cells by a tumour promoter. Science 1979; 206: 1089–1091
  • Zimmerman R., Cerutti P. Active oxygen acts as a promoter of transformation in mouse embryo C3H/10T1/2/C18 fibroblasts. Proceedings of the National Academy of Science of the United States of America 1984; 81: 2085–2087

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