13
Views
21
CrossRef citations to date
0
Altmetric
Original Article

The Inherent Cellular Sensitivity to 62·5 MeV(p→Be+) Neutrons of Human Cells Differing in Photon Sensitivity

, , &
Pages 805-812 | Received 05 Aug 1991, Accepted 06 Dec 1991, Published online: 03 Jul 2009

References

  • Barendsen G.W., Broerse J.J. Differences in radiosensitivity of cells from various types of experimental tumours in relation to RBE of 15 MeV neutrons. International Journal of Radiation Oncology, Biology and Physics 1977; 3: 211–214
  • Battermann J.J., Breur K., Hart G.A.M., Peperzeel H.A. Observations on pulmonary metastases in patients after single doses and multiple fractions of fast neutrons and cobalt-60 gamma rays. European Journal of Cancer 1981; 17: 539–548
  • Battermann J.J., Mijnheer B.J. The Amsterdam fast neutron therapy project: A final report. International Journal of Radiation Oncology, Biology and Physics 1986; 12: 2093–2099
  • Broerse J.J., Barendsen G.W. Relative biological effectiveness of fast neutrons for effects on normal tissues. Current Topics in Radiation Research Quarterly 1973; 8: 305–350
  • Budach V., Stuschke M., Budach W., Molls M., Sack H. Radiation response in 10 high-grade human soft tissue sarcoma xenografts to photons and fast neutrons. International Journal of Radiation Oncology, Biology and Physics 1990; 19: 941–943
  • Deacon J., Peckham M.J., Steel G.G. The radioresponsiveness of human tumours and the initial slope of the cell survival curve. Radiotherapy and Oncology 1984; 2: 317–323
  • Duncan W., Arnott S.J., Battermann J.J., Orr J.A., Schmitt G., Kerr G.R. Fast neutrons in the treatment of head and neck cancers: the results of a multi-centre randomly controlled trial. Radiotherapy and Oncology 1984; 2: 293–301
  • Duncan W., Orr J.A., Arnott S.J., Jack W.J., Kerr G.R., Williams J.R. Fast neutron therapy for squamous cell carcinoma in the head and neck region: results of a randomized trial. International Journal of Radiation Oncology, Biology and Physics 1987; 13: 171–178
  • Errington R.D., Ashby D., Gore S.M., Abrams K.R., Myint S., Bonnett D.E., Blake S.W., Saxton T.E. High energy neutron treatment for pelvic cancers: study stopped because of increased mortality. British Medical Journal 1991; 302: 1045–1051
  • Fauer G., Walker C. The response of endothelial cells to high energy neutron irradiation. International Journal of Radiation Biology 1991; 60: 33–38
  • Fertil B., Malaise E.P. Inherent cellular radiosensitivity as a basic concept for human tumour radiotherapy. International Journal of Radiation Oncology, Biology and Physics 1981; 7: 621–629
  • Fertil B., Deschavanne P.J., Gueulette J., Possoz A., Wambersie A., Malaise E.P. In vitro radiosensitization of six human cell lines. II. Relation to the RBE of 50MeV neutrons. Radiation Research 1982; 90: 526–537
  • Gragg R.L., Hamphrey R.M., Meyn R.E. The response of Chinese Hamster Ovary cells to fast neutron radiotherapy beams. II. Sublethal and potentially lethal damage recovery capabilities. Radiation Research 1977; 71: 461–470
  • Gragg R.L., Humphrey R.M., Thames H.D., Meyn R.E. The response of Chinese Hamster Ovary cells to fast neutron radiotherapy beams. III. Variation in relative biological effectiveness with position in cell cycle. Radiation Research 1978; 76: 283–291
  • Gray L.H., Conger A.D., Ebert M., Hornsey S., Scott O.C.A. The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy. British Journal of Radiology 1953; 26: 638–648
  • Gregoire V., Gueulette J., de Coster B.M., Octave-Prignot M., Wambersie A. Early repair kinetics of intestine and lung in mice, after fast neutron and photon irradiation. Stahlentherapie Onkologie 1989; 165: 272–275
  • Hall E.J., Novak J.K., Kellerer A.M., Rossie R.M., Marino S., Goodman L.J. RBE as a function of neutron energy. I. Experimental observations. Radiation Research 1975; 64: 245–255
  • Hall E.J., Withers H.R., Geraci J.P., Meyn R.E., Rasey J., Todd P., Sheline G.E. Radiological intercomparisons of fast neutron beams used for therapy in Japan and the United States. International Journal of Radiation Oncology, Biology and Physics 1979; 5: 277–233
  • Joiner M.C., Field S.B. The response of mouse skin to irradiation with neutrons from the 62 MV cyclotron at Chatterbridge, U.K. Radiotherapy Oncology 1988; 12: 153–166
  • Millar B.C., Fielden E.M., Millar J.L. Interpretation of survival-curve data for Chinese hamster cell line V-79 using the multitarget, multitarget with initial slope, and alpha, beta equations. International Journal of Radiation Biology 1978; 33: 599–603
  • Peacock J.H., Cassoni A.M., McMillan T.J., Steel G.G. Radiosensitive human tumour cell lines may not be recovery deficient. International Journal of Radiation Biology 1988; 54: 945–953
  • Steel G.G. Cellular sensitivity to low dose-rate irradiation focuses the problem of tumour radioresistance. Radiotherapy Oncology 1991; 20: 71–83
  • Taylor G.C., Scott M.C., Fletcher J.G. Microdosimetric measurements on the Clatterbridge neutron cancer therapy cyclotron. Radiation Protection Dosimetry 1990; 31: 443–447
  • Todd P., Geraci J.P., Furcinitti P.S., Rossi R.M., Mikage F., Theus R.B., Schroy C.B. Comparison of the effects of various cyclotron-produced fast neutrons on the reproductive capacity of cultured human kidney (T-1) cells. International Journal of Radiation Oncology, Biology and Physics 1978; 4: 1015–1022
  • Wambersie A. Fast neutron therapy at the end of 1988—a survey of the clinical data. Stahlentherapie Onkologie 1990; 166: 52–60
  • Warenius H.M., Errington R.D. Clinical aspects of particle radiotherapy. Radiobiology in Radiotherapy. Springer Verlag, London 1987, Chapter 13.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.