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Original Article

Inactivation of C3H 10T½ Cells by Monoenergetic High LET Alpha-particles

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Pages 813-820 | Received 04 Oct 1991, Accepted 11 Jan 1992, Published online: 03 Jul 2009

References

  • Barendsen G.W. LET dependence of linear and quadratic terms in dose-response relationships for cellular damage: correlations with the dimensions and structures of biological targets. Radiation Protection Dosimetry 1990; 31: 235–239
  • Bertram J.S., Heidelberger C. Cell cycle dependency of oncogenic transformation induced by N-methyl-N′-nitro-N-nitrosoguanidine in culture. Cancer Research 1974; 34: 526–537
  • Bettega D., Calzolari P., Ottolenghi A., Tallone-Lombardi L. Oncogenic transformation induced by high and low LET radiations. Radiation Protection Dosimetry 1990; 31: 279–283
  • Biersack J.P., Ziegler J.F. TRIM 91, The Transport of Ions in Matter. IBM Research, Yorktown, NY 1991, version 91.00. 10598
  • Bird R.P., Rohrig N., Colvett R.D., Geard C.R., Marino S.A. Inactivation of synchronized chinese hamster V79 cells with charged-particle track segments. Radiation Research 1980; 82: 277–289
  • Brenner D.J. Radon: current challenges in cellular radiobiology. International Journal of Radiation Biology 1992; 61: 3–13
  • Cartwright B.G., Shirk E.K., Price P.B. A nuclear track recording polymer of unique sensitivity and resolution. Nuclear Instruments and Methods 1978; 153: 457–460
  • Cox. R., Thacker J., Goodhead D.T., Munson J.R. Mutation and inactivation of mammalian cells by various ionising radiations. Nature 1977; 267: 425–427
  • Goodhead D.T., Munson R.J., Thacker J., Cox R. Mutation and inactivation of cultured mammalian cells exposed to beams of accelerated heavy ions. IV. Biophysical interpretation. International Journal of Radiation Biology 1980; 37: 135–167
  • Hieber L., Ponsel G., Roos H., Fenn S., Fromke E., Kellerer A.M. Absence of a dose-rate effect in transformation of C3H10T½ by α-particles. International Journal of Radiation Biology 1987; 52: 859–869
  • Iliakis G., Wright E., Ngo F.Q.H. Possible importance of PLD repair in the modulation of BrdUrd and IdUrd-mediated radiosensitization in plateau-phase C3H10T½ mouse embryo cells. International Journal of Radiation Biology 1987; 51: 541–548
  • Inkret W.C., Eisen Y., Harvey W.F., Koehler A.M., Raju M.R. Radiobiology of α particles. I. Exposure system and dosimetry. Radiation Research 1990; 123: 304–310
  • James F., Roos M. Function Minimization and Error Analysis. CERN Computer Center Program Library D506, Geneva 1983
  • Kennedy A.R., Fox M., Murphy G., Little J.B. Relationship between X-ray exposure and malignant transformation in C3H 10T½ cells. Proceedings of the National Academy of Sciences, USA 1980; 77: 7262–7266
  • Kraft G. Radiobiological effects of very heavy ions: inactivation, induction of chromosome aberrations and strand breaks. Nuclear Science Applications 1987; 3: 1–28
  • Lloyd E.L., Gemmell M.A., Henning C.B., Cemmell D.S., Zabransky B.J. Cell survival following multiple-track alpha particle irradiation. International Journal of Radiation Biology 1979; 35: 23–31
  • Mothersill C., Seymour C. The influence of lethal mutations on the quantification of radiation transformation frequencies. International Journal of Radiation Biology 1987; 51: 723–729
  • Nagasawa H., Little J.B. Induction of chromosome aberrations and sister chromatid exchanges by X-rays in density-inhibited cultures of mouse 10T½ cells. Radiation Research 1981; 87: 538–551
  • Nagasawa H., Robertson J., Little J.B. Induction of chromosomal aberrations and sister chromatid exchanges by alpha particles in density-inhibited cultures of mouse 10T½ and 3T3 cells. International Journal of Radiation Biology 1990; 57: 35–44
  • Otsu H., Yasukawa M., Terasima T. In vitro properties and tumorigenicity of radiation-transformed clones of mouse 10T½ cells. Journal of Radiation Research 1983; 24: 118–130
  • Pardee A.B. G1 events and regulation of cell proliferation. Science 1989; 246: 603–608
  • Raju M.R., Eisen Y., Carpenter S., Inkret W.C. Radiobiology of α particles. III. Cell inactivation by α particle traversal of the cell nucleus. Radiation Research 1991; 128: 204–209
  • Reznikoff C.A., Brankow D.W., Heidelberger C. Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of growth. Cancer Research 1973; 33: 3231–3238
  • Roberts C.J., Goodhead D.T. The effect of 238Pu α-particles on the mouse fibroblast cell line C3H10T½: characterization of source and RBE for cell survival. International Journal of Radiation Biology 1987; 52: 871–882
  • Schillaci M.E., Carpenter S., Raju M.R., Sebring R.J., Wilder M.E., Goodhead D.T. Radiobiology of ultrasoft X-rays. II. Cultured C3H mouse cells (10T½). Radiation Research 1989; 118: 83–92
  • Sinclair R., Bishop D.H.L. Synchronous culture of strain-L mouse cells. Nature 1965; 205: 1272–1273
  • Stranden E. Radon in dwellings and lung cancer—a discussion. Health Physics 1980; 38: 301–306
  • Terzaghi M., Little J.B. Repair of potentially lethal radiation damage in mammalian cells is associated with enhancement of malignant transformation. Nature 1975; 253: 548–549
  • Tretyakova S.P., Borcea C., Kalpakchieva R. The use of CR-39 plastic detector for the detection and identification of ions with 2 ≤ Z ≤ 5. Nuclear Instruments and Methods 1984; 221: 371–377
  • Wulf H., Kraft-Weyrather W., Miltenburger H.G., Blakely E.A., Tobias C.A., Kraft G. Heavy ion effects on mammalian cells: inactivation measurements with different cell lines. Radiation Research 1985; 104: S122–S134
  • Yang T.C.H., Craise L.M., Mei M.T., Tobias C.A. Neoplastic cell transformation by heavy charged particles. Radiation Research 1985; 104: S177–S187
  • Ziegler J.F. Helium Stopping Powers and Ranges in all Elements. Pergamon Press, New York 1977

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