17
Views
7
CrossRef citations to date
0
Altmetric
Original Article

Strontium-90 Induced Bone Tumours in Beagle Dogs: Effects of Route of Exposure and Dose Rate

, , , &
Pages 821-831 | Received 26 Jun 1991, Accepted 26 Nov 1991, Published online: 03 Jul 2009

References

  • Benjamin S.A., Hahn F.F., Chiffelle T.L., Boecker B.B., Hobbs C.H., Jones R.K., McClellan R.D., Snipes M.B. Occurrence of hemangiosarcomas in beagles with internally deposited radionuclides. Cancer Research 1975; 35: 1745–1755
  • Dougherty T.F., Stover B.J., Dougherty J.H., Jee W.S.S., Mays C.W., Rehfeld C.E., Christensen W.R., Goldthorpe H.C. Studies of the biological effects of 226Ra, 239Pu, 228Ra, 228Th, and 90Sr in adult beagles. Radiation Research 1962; 17: 625–681
  • Evans R.D. The effect of skeletal deposited alpha-ray emitters in man. British Journal of Radiology 1966; 39: 881–895
  • Finkel M.P., Biskis B.O., Greco I., Camden R.W. Strontium-90 toxicity in dogs: status of Argonne study on influence of age and dosage pattern. Biomedical Implications of Radiostrontium Exposure, M. Goldman, L.K. Bustad. US Atomic Energy Commission Conference, US Department of Commerce, Springfield, VA 1972; 285–308
  • Gillettt N.A., Muggenburg B.A., Boecker B.B., Hahn F.F., Seiler F.A., Rebar A.H., Jones R.K., McClellan R.O. Single inhalation exposure to 90SrCl2 in the Beagle dog: Hematological effects. Radiation Research 1987a; 110: 267–288
  • Gillett N.A., Muggenburg B.A., Boecker B.B., Griffith W.C., Hahn F.F., McClellan R.O. Single inhalation exposure to 90SrCl2 in the beagle dog: late biological effects. Journal of the National Cancer Institute 1987b; 79: 359–376
  • Gossner W. Pathogenesis of radionuclide-induced bone tumors. Metals in Bone, N.D. Priest. MTP, Lancaster 1984; 303–320, EULEP
  • Howard E.B., Clarke W.J., Karagianes M.T., Palmer R.F. Strontium-90 induced bone tumors in miniature swine. Radiation Research 1969; 39: 594–602
  • Current Veterinary Therapy. X. Small Animal Practice, R.W. Kirk. W. B. Saunders, Philadelphia 1989
  • Lloyd R.D., Mays C.W., Atherton D.R. Distribution of injected 226Ra and 90Sr in the beagle skeleton. Health Physics 1976; 30: 183–189
  • Mays C.W., Spiess H. Bone sarcomas in patients given radium-224. Radiation Carcinogenesis: Epidemiology and Biological Significance, J.D. Boice, J.F. Fraumeni. Raven Press, New York 1984; 241–252
  • Mays C.W., Dougherty T.F., Taylor G.N., Lloyd R.D., Stover B.J., Jee W.S.S., Christensen W.R., Dougherty J.H., Atherton D.R. Radiation-induced bone cancer in beagles. Delayed Effects of Bone-Seeking Radionuclides, C.W. Mays, W.S.S. Jee, R.D. Lloyd, B.J. Stover, J.H. Dougherty, G.N. Taylor. University of Utah Press, Salt Lake City 1969; 387–498
  • McClellan, R.O., Jones, R.K. 90Sr-induced neoplasia: a selective review. Delayed Effects of Bone-Seeking Radionuclides, C.W. Mays, Jee, W.S., Lloyd, R.D., et al. University of Utah Press, Salt Lake City 1969; 293–322
  • Annual report of the fission product inhalation program, 1966–67, R.O. McClellan, F.C. Rupprecht. US Atomic Energy Commission Report, LF-38, 1967; 1–8
  • Momeni M.H., Jow N., Bradley E. Temporal and spatial marrow dose from 90Sr-90Y in beagles: A measurement of geometry-distribution factor. Health Physics 1975; 288: 285–294
  • Momeni M.H., Jow N., Bradley E. 90Sr-90Y dose distribution in beagles: Injection relative to ingestion. Health Physics 1976; 30: 3–19
  • Nilsson A., Bierke P., Walinder G., Broomé-Karlsson A. Age and dose-related carcinogenicity of 90Sr. Acta Radiologica 1980; 19: 223–228
  • Nilsson A., Morgan J.P., Book S.A. Investigations of 90Sr in dogs. I. Pathogenesis of radiation-induced bone tumors. Acta Radiologica 1985; 24: 95–111
  • Parks N.J. Dynamics of life-span strontium-90 distribution in beagles with uniformly labeled skeletons acquaired by radionuclide ingestion from in utero to adulthood. Metals in Bone, N.D. Priest. MTP Press Ltd, Lancaster 1984; 107–115, CEUP
  • Pool R.R. Tumors of bone and cartilage. Tumors of Domestic Animals3rd edn, J.E. Moulton. University of California Press, Berkeley 1990
  • Pool R.R., Romer W.R.J., Goldman M. Induction of tumors involving bone in beagles fed toxic levels of strontium-90. American Journal of Roentgenology Radium Therapy Nuclear Medicine 1973; 4: 900–908
  • Pool R.R., Morgan J.P., Parks N.J. Comparative pathogenesis of radium-induced intracortical bone in lesions in humans and beagles. Health Physics 1983; 44: 155–177
  • Raabe O.G., Book S.A., Parks N.J., Chrisp C.E., Goldman M. Lifetime studies of 226Ra and 90Sr toxicity in beagles—a status report. Radiation Research 1981a; 86: 515–528
  • Raabe O.G., Parks N.J., Book S.A. Dose-response relationships for bone tumors in beagles exposed to 226Ra and 90Sr. Health Physics 1981b; 40: 863–880
  • Raabe O.G., Book S.A., Parks N.J. Lifetime bone cancer dose-response relationships in beagles and people from skeletal burdens of 226Ra and 90Sr. Health Physics 1983; 44: 33–48
  • Roessner A., Hobik H.P., Immenkamp M., Grundmann E. Ultrastructure of telangiectatic osteosarcoma. Journal of Cancer Research and Clinical Oncology 1979; 95: 197–207
  • Rosner B. Fundamentals of Biostatistics. Duxbury Press, Boston 1982; 324–329, section 10.6
  • UNSCEAR. Report: Sources, Effects and Risks of Ionizing Radiation. United Nations, New York 1988
  • Vaughan J., Williamson M. 90Sr in the rabbit: The relative risks of osteosarcoma and squamous cell carcinoma. Delayed Effects of Bone-Seeking Radionuclides, C.W. Mays, W.S. Jee, R.D. Lloyd, B.J. Stover, J.H. Dougherty, G.N. Taylor. University of Utah Press, Salt Lake City 1969; 337–355

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.