Transformation and Radiosensitivity of Human Diploid Skin Fibroblasts Transfected with SV40 T-antigen Mutants Defective in RB and P53 Binding Domains

References

• Arlett C.F., Green M.H.L., Priestley A., Harcourt S.A., Mayne L.V. Comparative human cellular radiosensitivity: I. The effect of SV40 transformation and immortalization on the gamma-irradiation survival of skin derived fibroblasts from normal individuals and from ataxia-telangiectasia patients and heterozygotes. International Journal of Radiation Biology 1988; 54: 911–928
   PubMed Web of Science ®Google Scholar
• Carroll R.B., Hager K., Dulbecco R. Simian virus 40 T-antigen binds to DNA. Proceedings of the National Academy of Sciences, USA 1974; 71: 3754–3757
   PubMed Web of Science ®Google Scholar
• Chen S., Paucha E. Indentification of a region of simian virus 40 large T antigen required for cell transformation. Journal of Virology 1990; 64: 3350–3357
   PubMed Web of Science ®Google Scholar
• Clark R., Lane D.P., Tjian R. Use of monoclonal antibodies as probes of simian virus 40 T antigen ATPase activity. Journal of Biological Chemistry 1981; 256: 11854–11858
   PubMed Web of Science ®Google Scholar
• DeCaprio J.A., Ludlow J.W., Figge J., Shew J.-Y., Huang C.-M., Lee W.-H., Marsilio E., Paucha E., Livingston D.M. SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. Cell 1988; 54: 275–283
   PubMed Web of Science ®Google Scholar
• Eddy B.Z., Borman G.S., Grubbs G.Z., Young R.D. Identification of the oncogenic substance in rhesus monkey kidney cell cultures as simian virus 40. Virology 1962; 17: 65–72
   PubMed Web of Science ®Google Scholar
• Fertil B., Dertinger H., Courdi A., Malaise E.P. Mean inactivation dose: A useful concept for intercomparison of human cell survival curves. Radiation Research 1984; 99: 73–84
   PubMed Web of Science ®Google Scholar
• Finley C.A., Philip W.H., Levine A.J. The p53 proto-oncogene can act as a suppressor of transformation. Cell 1989; 57: 1083–1093
   PubMed Web of Science ®Google Scholar
• Friend S.H., Bernards R., Rogeli S., Weinberg R.A., Rapaport J.M., Albert D.M., Dryja T.P. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcomas. Nature (London) 1986; 323: 643–646
   PubMed Web of Science ®Google Scholar
• Jat P.S., Sharp P. Large T antigens of simian virus 40 and polyomavirus efficiently establish primary fibroblasts. Journal of Virology 1986; 59: 746–750
   PubMed Web of Science ®Google Scholar
• Kalderon D., Smith A.E. In vitro mutagenesis of a putative DNA binding domain of SV40 large-T. Virology 1984; 139: 109–137
   PubMed Web of Science ®Google Scholar
• Kano Y., Little J.B. Efficient immortalization by SV40 T DNA of skin fibroblasts from patients with Wilms' tumor associated with chromosome 11P deletion. Molecular Carcinogenesis 1989; 2: 314–321
   PubMed Web of Science ®Google Scholar
• Lane D.P., Crawford L.V. T-antigen is bound to a host protein in SV40-transformed cells. Nature (London) 1979; 278: 261–263
   PubMed Web of Science ®Google Scholar
• Lee E.Y.H.P., To H., Slew J.-Y., Bookstein R., Scully P., Lee W.H. Inactivation of the retinoblastoma susceptibility gene in human breast cancers. Science 1988; 241: 218–221
   PubMed Web of Science ®Google Scholar
• Lewis A.M., Jr., Martin R.G. Oncogenicity of simian virus 40 deletion mutants that induce altered 17-kilodalton t-protein. Proceedings of the National Academy of Sciences, USA 1979; 76: 4299–4302
   PubMed Web of Science ®Google Scholar
• Linzer D.I.H., Levine A.J. Characterization of a 54k dalton cellular SV40 tumor antigen present in SV40 transformed cells and uninfected embryonal carcinoma cells. Cell 1979; 17: 43–52
   PubMed Web of Science ®Google Scholar
• Little J.B., Nove J. Sensitivity of human diploid fibroblast cell strains from various genetic disorders to acute and protracted radiation exposure. Radiation Research 1990; 123: 87–92
   PubMed Web of Science ®Google Scholar
• Martin R.G. The transformation of cell growth and transmogrification of DNA synthesis by simian virus 40. Advances in Cancer Research 1981; 34: 1–68
   PubMedGoogle Scholar
• McKay R.D.G. Binding of a simian virus 40 T-antigen-related protein to DNA. Journal of Molecular Biology 1981; 145: 471–488
   PubMed Web of Science ®Google Scholar
• Peden K.W.C., Pipas J.M., Pearson-White S., Nathans D. Isolation of mutants of an animal virus in bacteria. Science 1980; 209: 1392–1396
   PubMed Web of Science ®Google Scholar
• Peden K.W.C., Spinivasan A., Faber J.M., Pipas J.M. Mutants with changes within or near a hydrophobic region of simian virus 40 large tumor antigen are defective for binding cellular protein p53. Virology 1989; 168: 13–21
   PubMed Web of Science ®Google Scholar
• Pipas J.M., Peden K.W.C., Nathans D. Mutational analysis of simian virus 40 T antigen: isolation and characterization of mutants with deletions in the T-antigen gene. Molecular and Cellular Biology 1983; 3: 203–213
   PubMed Web of Science ®Google Scholar
• Prives C. The replication function of SV40 T antigen are regulated by phosphorylation. Cell 1990; 61: 735–738
   PubMed Web of Science ®Google Scholar
• Ray F.A., Peabody D.S., Cooper J.L., Cram L.S., Kraemer P.M. SV40 T antigen alone drives karyotype instability that precedes neoplastic transformation of human diploid fibroblasts. Journal of Cell Biochemistry 1990; 42: 13–31
   PubMed Web of Science ®Google Scholar
• Su L.-N., Little J.B. Transformation and radiosensitivity of human diploid skin fibroblasts transfected with activated ras oncogene and SV40 T-antigen. International Journal of Radiation Biology 1992, 1992
   Web of Science ®Google Scholar
• Tjian R., Fey G., Graessmann A. Biological activity of purified simian virus 40 T-antigen proteins. Proceedings of the National Academy of Sciences, USA 1978; 75: 1279–1283
   PubMed Web of Science ®Google Scholar
• Tjian R., Robbins A. Enzymatic activities associated with purified simian virus 40 T-antigen proteins. Proceedings of the National Academy of Sciences, USA 1979; 76: 610–615
   PubMed Web of Science ®Google Scholar
• Tooze J. Molecular Biology of Tumor Viruses2nd edition. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 1981, Part 2,
   Google Scholar
• Topp W.C., Rifkin D.B., Sleigh M.J. SV40 mutants with an altered small-t protein are tumorigenic in newborn hamsters. Virology 1981; 111: 341–350
   PubMed Web of Science ®Google Scholar