Advanced search
Publication Cover
International Journal of Radiation Biology Volume 62, 1992 - Issue 6
Submit an article Journal homepage
4
Views
1
CrossRef citations to date
0
Altmetric
Original Article

Lack of Differential G2 Chromosomal Radiosensitivity between Non-tumorigenic and Tumorigenic Human Hybrid Cells (HeLa × Skin Fibroblasts)

J.L. Redpath Department of Radiological Sciences, University of California, Irvine, CA, 92717, USA
,
C. Sun Department of Radiological Health Sciences, Colorado State University, Fort Collins, CO, 80523, USA
,
M. Colman Department of Radiological Sciences, University of California, Irvine, CA, 92717, USA
,
B. Loucas Department of Radiological Health Sciences, Colorado State University, Fort Collins, CO, 80523, USA
,
M. Muhllman-Diaz Department of Radiological Sciences, University of California, Irvine, CA, 92717, USA
&
J.S. Bedford Department of Radiological Health Sciences, Colorado State University, Fort Collins, CO, 80523, USA
Pages 679-685 | Received 06 Apr 1992, Accepted 23 Jul 1992, Published online: 03 Jul 2009

References

  • Bedford J.S., Mitchell J.B., Griggs H.G., Bender M.A. Radiation-induced cellular reproductive death and chromosome aberrations. Radiation Research 1978; 76: 573–586
  • Bender M.A., Viola M.V., Fiore J., Thompson M.H., Leonard R.C. Normal G2 chromosomal sensitivity and cell survival in the cancer family syndrome. Cancer Research 1988; 48: 2579–2584
  • Bender M.A., Viola M.V. Reply to Correspondence re: Michael Bender, et al., Normal G2 chromosomal radiosensitivity and cell survival in the cancer family syndrome. Cancer Research 1989; 48: 2579–2584, 1988, Cancer Research, 49, 4672–4673.
  • Carrano A.V. Chromosome aberrations and radiation-induced cell death. I. Transmission and survival parameters of aberrations. Mutation Research 1973a; 17: 341–353
  • Carrano A.V. Chromosome aberrations and radiation-induced cell death. II. Predicted and observed survival. Mutation Research 1973b; 17: 355–366
  • Colman M., Bhatt S., Candelaria M., Sun C., Redpath J.L. A comparison of the radiation sensitivities of non-tumorigenic and tumorigenic human hybrid cell lines. International Journal of Radiation Biology 1988; 53: 609–616
  • Dewey W.C., Stone L.E., Miller H.H., Giblak R.E. Radiosensitization with 5-bromodeoxyuridine of Chinese hamster cells X-irradiated during different phases of the cell cycle. Radiation Research 1971a; 47: 672–688
  • Dewey W.C., Miller H.H., Leeper D.B. Chromosomal aberrations and mortality of X-irradiated mammalian cells; emphasis on repair. Proceedings of the National Academy of Sciences, USA 1971b; 68: 667–661
  • Gantt R., Sanford K.K., Parshad R., Price F.M., Peterson W.D., Jr., Rhim J.S. Enhanced G2 chromatid radiosensitivity, an early stage in the neoplastic transformation of human epidermal keratinocytes in culture. Cancer Research 1987; 47: 1390–1397
  • Nagasawa H., Little J.B. Comparision of kinetics of X-ray-induced cell killing in normal, ataxia telaragiectasia, and hereditary retinoblastoma fibroblasts. Mutation Research 1983; 109: 297–308
  • Nagasawa H., Latt S.A., Lalande M.E., Little J.B. Effects of X-irradiation on cell cycle progression, induction of chromosomal aberations, and cell killing in ataxia telaragiectasia (AT) fibroblasts. Mutation Research 1985; 148: 71–82
  • Nagasawa H., Little J.B. Radiosensitivities of ten apparently normal human diploid fibroblast strains to cell-killing, G2-phase chromosomal aberrations, and cell cycle delay. Cancer Research 1988; 48: 4535–45538
  • Parshad R., Sanford K.K., Jones G.M. Chromosomal sensitivity during the G2 cell cycle period of skin fibroblasts from individuals with familial cancer. Proceedings of the National Academy of Sciences, USA 1985; 82: 5400–5403
  • Redpath J.L., Sun C. Sensitivity of a human hybrid cell line (HeLa × skin fibroblast) to radiation-induced neoplastic transformation in G2, M and mid-G1 phases of the cell cycle. Radiation Research 1990; 121: 206–211
  • Redpath J.L., Sun C., Colman M., Stanbridge E.J. Radiobiological studies of human hybrid cells (skin fibroblasts × HeLa) and their tumorigenic segregants. International Journal of Radiation Biology 1985; 48: 479–483
  • Revell S.H. Relationships between chromosome damage and cell death. Radiation-Induced Chromosome Damage in Man, T. Ishihara, M.S. Sasaki. Alan R. Liss, Inc, New York 1983; 215–233, In
  • Russell W.C., Newman C., Williamson D.H. A simple cytochemical technique for demonstration of DNA in cells infected with mycoplasmas and viruses. Nature 1975; 253: 461–462
  • Sanford K.K., Parshad R., Gantt R.R., Tarone R.E. A deficiency in chromatin repair, genetic instability, and predisposition to cancer. Critical Reviews in Oncology 1989a; 1: 323–341
  • Sanford K.K., Parshad R., Stanbridge E.J., Frost J.K., Jones G.M., Wilkinson J.E., Tarone R.E. Chromosomal radiosensitivity during the G2 cell cycle period and cytopathology of human normal × tumor cell hybrids. Cancer Research 1986; 46: 2045–2049
  • Sanford K.K., Parshad R., Tarone R.E. Correspondence re: Michael Bender, et al., Normal G2 chromosomal radiosensitivity and cell survival in the cancer family syndrome. Cancer Research 1989b; 48: 2579–2584, 1988, Cancer Research, 49, 4671–4672.
  • Savage J.R.K. Classification and relationships of induced chromosomal structural changes. Journal of Medical Genetics 1975; 12: 103–122
  • Stanbridge E.J., Flandemeyer R.R., Daniels D.W., Nelson-Rees W.A. Specific chromosome loss associated with expression of tumorigenicity in human cell hybrids. Somatic Cell Genetics 1981; 7: 699–712
  • Stanbridge E.J. der C.J., Doersen C.J., Nishimi R.Y., Peehl D.M., Weissman B.E., Wilkinson J.E. Human cell hybrids: analysis of transformation and tumorigenicity. Science (Washington, DC) 1982; 215: 252–259

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.