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Original Article

Dependence of the Yield of Strand Breaks Induced by γ-rays in DNA on the Physical Conditions of Exposure: Water Content and Temperature

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Pages 289-296 | Received 03 Apr 1992, Accepted 29 Sep 1992, Published online: 03 Jul 2009

References

  • Baverstock K.F., Will S. Evidecence for the dominance of direct excitation of DNA in the formation of strand breaks in cells following irradiation. International Journal of Radiation Biology 1989; 55: 563–568
  • Blazek E.R., Peak M.J. The role of hydroxyl radical quencing in the protection by acetate and ethylenediaminetetraacetate of supercoiled plasmid DNA from ionizing radiation-induced strand breakage. International Journal of Radiation Biology 1988; 53: 237–247
  • Hearst J.E., Vinograd J. The net hyudration of nucleic acid. Proceedings of the National Academy of Sciences of the United States of America 1961; 47: 825–830
  • Hempel K., Mildenberger E. Determination of G-values for single and double strand break inducation in plasmid DNA using agarose gel electrophoresis and a curve-fitting procedure. International Journal of Radiation Biology 1987; 52: 125–138
  • Hüttermann J., Röhrig M., Köhnlein W. Free radical from irradiated lyophilized DNA: influence of water of hydration. International Journal of Radiation Biology 1992; 61: 299–313
  • Jeffrey G., Saenger W. Hydrogen Bonding in Biological Structures. Springer-Verlag, New York 1991
  • Kevan L. Radiation chemistry of frozen aqueous solution. Radiation Chemistry of Aqueous Systems, G. Stein. Weizmann Science Press, Jerusalem 1968; 21–71, In
  • Klimczak U., Mark F., Worm K.-H., Schulte-Frohlinde E.D. Lethal damage in γ-irradiated plasmid DNA as a function of scavenger concentration. 40th Annual Meeting of the Radiation Research Society. P-21-2, The Radiation Research Society, Reston 1992
  • Krisch R.E., Flick M.B., Trumbore C.N. Radiation chemical mechanisms of single- and double-strand break formation in irradiated SV40 DNA. Radiation Research 1991; 126: 251–259
  • Lemotte P.K., Little J.B. DNA damage induced in human diploid cells by decay of incorporated radionucleotides. Cancer Research 1984; 44: 1337–1342
  • Lett J.T., Alexander P. Crosslinking and degradation of deoxyribonucleic acid gels with varying water contents when irradiated with electrons. Radiation Research 1961; 15: 159–173
  • Mathur-de Vré R., Bertinchamps A.J., Berendsen H.J.C. The effects of irradiation on the hydration characteristics of DNA and polynucleotides. I. An NMR study of frozen H2O and D2O solutions. Radiation Research 1976; 68: 197–214
  • Neary G.J., Simpson-Gildemeister V.F.W., Peacocke A.R. The influence of radiation quality and oxygen on strand breakage in dry DNA. International Journal of Radiation Biology 1970; 18: 25–40
  • Peak M.J., Stickley C.D., Peak J.G., Ito T. Strand breakage caused by gamma radiation in supercoiled DNA in the dry, humid and aqueous states. Radiation Research, Vol. 1, J.D. Chapman, W.D. Dewey, G.F. Whitmore. Academic Press, San Diego 1991; 121–121, In
  • Roots R., Kraft G., Gosschalk E. The formation of radiation-induced DNA breaks: the ratio of double-strand breaks to single-strand breaks. International Journal of Radiation Oncology Biology Physics 1985; 11: 259–265
  • Saenger W. Principles of Nucleic Acid Structure. Springer-Verlag, New York 1984
  • Sagstuen E., Hole E.O., Nelson W.H., Close D.M. The effect of environment upon DNA free radicals. The Early Effects of Radiation on DNA, E.M. Fielden, P. O'Neill. Springer-Verlag, New York 1991; 213–230, In
  • Siddiqi M.A., Bothe E. Single- and double-strand break formation in DNA irradiated in aqueous solution: dependence on dose and OH radical scavenger concentration. Radiation Research 1987; 112: 449–463
  • Spotheim-Maurizot M., Charlier M., Sabattier R. DNA radiolysis by fast neutrons. International Journal of Radiation Biology 1990; 57: 301–313
  • Steenken S. Purine bases, nucleosides, and nucleotides: aqueous solution redox chemistry and transformation reactions of their radical cations and e- and OH adducts. Chemical Reviews 1989; 89: 503–520
  • Swarts S.G., Sevilla M.D., Becker D., Tokar C.J., Wheeler K.T. Radiation-induced DNA damage as a function of hydration. I. Release of unaltered bases. Radiation Research 1992; 129: 333–344
  • Symons M.C.R. Application of electron spin resonance spectroscopy to the study of the effects of ionising radiation on DNA and DNA complexes. Journal of Chemical Society, Faraday Transactions 1 1987; 83: 1–11
  • Symons M.C.R. The role of radiation induced charge migration with DNA: ESR studies. The Early Effects of Radiation on DNA, E.M. Fielden, P. O'Neill. Springer-Verlag, New York 1991; 111–124, In
  • Van Lith D., de Haas M.P., Warman J.M., Hummel A. Highly mobile charge carriers in hydrated DNA and collagen formed by pulse ionization. Biopolymers 1983; 22: 807–810
  • Van Lith D., Warman J.M., de Haas M.P., Hummel A. Electron migration in hydrated DNA and collagen at low temperatures. Part 1—Effect of water concentration. Faraday Transactions of the Journal of the Chemical Society 1986; 82: 2933–2943
  • Van Touw J.H., Verbene J.B., Retel J., Loman H. Radiation-induced strand breaks in øX174 replicative form DNA: an improved experimental and theoretical approach. International Journal of Radiation Biology 1985; 48: 567–578
  • von Sonntag C. The Chemical Basis of Radiation Biology. Taylor & Francis, London 1987
  • Ward J.F. Some biochemical consequences of the spatial distribution of ionizing radiation-produced free radicals. Radiation Research 1981; 86: 185–195
  • Ward J.F. Ionizing radiation induced DNA damage: identities and DNA repair. Mechanisms of DNA Damage and Repair, M.G. Simic, L. Grossman, A.C. Upton. Plenum Press, New York and London 1986; 135–138, In
  • Ward J.F., Webb C.F., Limoli C.L., Milligan J.R. DNA lesions produced by ionizing radiation: locally multiply damaged sites. Ionizing Radiation Damage to DNA: Molecular Aspects, S.S. Wallace, R.B. Painter. Wiley-Liss, New York 1990; 43–50, In
  • Yoshimura T., Miyazaki T., Mochizuki S., Suzuki K., Watanabe M. Do OH radicals react with organic substances in gamma-irradiated frozen cells of golden hamster embryo?. Radiation Physics and Chemistry 1992; 40: 45–48

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