Liposomal Muramyl Tripeptide Phosphatidylethanolamine (MTP-PE) Promotes Haemopoietic Recovery in Irradiated Mouse

References

• Adam A., Lederer E. Muramylpeptides as immunomodulators. ISI Atlas of Science. Immunology 1988; 1: 205–214
   Google Scholar
• Ainsworth E.J. From endotoxins to newer immunomodulators: survival-promoting effects of microbial polysaccharide complexes in irradiated animals. Pharmacology and Therapeutics 1988; 39: 223–241
   PubMed Web of Science ®Google Scholar
• Baschang G. Muramylpeptides and lipopeptides: studies towards immunostimulants. Tetrahedron 1989; 45: 6331–6360
   Google Scholar
• Behling U.H. The radioprotective effect of bacterial endotoxin. Beneficial Effects of Endotoxin, A. Nowotny. Plenum, New York 1983; 127–148, In
   Google Scholar
• Broudy V.C., Kaushansky K., Shoemaker S.G., Aggarval B.B., Adamson J.W. Muramyl dipeptide induces production of hemopoietic growth factors in vivo by a mechanism independent of tumor necrosis factor. Journal of Immunology 1990; 144: 3789–3794
   Google Scholar
• Creaven P.J., Cowens J.W., Brenner D.E., Dadey B.M., Han T., Huben R., Karakousis C., Frost H., LeSher D., Hanagan J., Andrejcio K., Cushman M.K. Initial clinical trial of the macrophage activator muramyl tripeptide-phosphatidylethanolamine encapsulated in liposomes in patients with advanced cancer. Journal of Biological Response Modifiers 1990; 9: 492–498
   PubMedGoogle Scholar
• Denekamp J. Cell kinetics and radiation biology. International Journal of Radiation Biology 1986; 49: 357–380
   Web of Science ®Google Scholar
• Deyev L.I., Kravtzov G.M., Kudryashov Y.B. Radioprotective action of liposomes containing serotonin. Radiobiologiya 1976; 16: 287–289
   Google Scholar
• Eppstein D.A., Van Der Pas M.A., Fraser-Smith E.B., Kurahara C.G., Felgner P.L., Matthews T.R., Waters R.V., Venuti M.C., Jones G.H., Metha R., Lopez-Berestein G. Liposome-encapsulated muramyl dipeptide analogue enhances non-specific host immunity. International Journal of Immunotherapy 1986; 2: 115–126
   Google Scholar
• Faradji A., Bohbot A., Frost H., Schmitt-Goguel M., Siffert J.C., Dufour P., Eber M., Lallot C., Wiesel M.L., Bergerat J.P., Oberling F. Phase I study of liposomal MTP-PE-activated autologous monocytes administered intraperitoneally to patients with peritoneal carcinomatosis. Journal of Clinical Oncology 1991; 9: 1251–1260
   Google Scholar
• Fedoročko P., Brezáni P., Macková N. Radioprotection of mice by the bacterial extract Broncho-Vaxom: haemopoietic stem cells and survival enhancement. International Journal of Radiation Biology 1992; 61: 511–518
   Web of Science ®Google Scholar
• Fidler I.J. Macrophages and metastasis—a biological approach to cancer therapy: presidential address. Cancer Research 1985; 45: 4714–4726
   PubMed Web of Science ®Google Scholar
• Fidler I.J. Immunomodulation of macrophages for cancer and antiviral therapy. Site-Specific Drug Delivery, E. Tomlinson, S.S. Davis. Wiley, Chichester 1986; 111–118, In
   Google Scholar
• Fidler I.J., Nii A., Utsugi T., Brown D., Bakouche O., Kleinerman E.S. Differential release of TNF-alpha, IL-1, and PGE2 by human blood monocytes subsequent to interaction with different bacterial-derived agents. Lymphokine Research 1990; 9: 449–463
   Google Scholar
• Frost H., Murray J.L., Chaudri H.A., Van Damme J. Interleukin-6 induction by a muramylpeptide derivative in cancer patients. Journal of Biological Response Modifiers 1990; 9: 160–166
   PubMedGoogle Scholar
• Galelli A., Charlot B., Phillips N.C., Chedid L. Induction of colony-stimulating activity in mice by injection of liposomes containing lipophilic muramyl peptide derivatives. Cancer Research 1989; 49: 810–815
   PubMed Web of Science ®Google Scholar
• Galelli A., Chedid L. Modulation of myelopoiesis in vivo by synthetic adjuvant-active muramyl peptides: induction of colony-stimulating activity and stimulation of stem cell proliferation. Infection and Immunity 1983; 42: 1081–1085
   Google Scholar
• Galelli A., Lefrancier P., Chedid L. Colony-stimulating activity induced by synthetic muramyl peptides: variation with chemical structure and association with anti-infectious activity. Infection and Immunity 1984; 46: 495–500
   Google Scholar
• Hoogevest P. van, Fankhauser P. An industrial liposomal dosage form for muramyl-tripeptide-phosphatidylethanolamine (MTP-PE). Liposomes in the Therapy of Infectious Diseases and Cancer, G. Lopez-Berestein, I.J. Fidler. Liss, New York 1989; 453–466, In
   Google Scholar
• Kleinerman E.S., Erickson K.L., Schroit A.J., Fogler W.E., Fidler I.J. Activation of tumoricidal properties in human blood monocytes by liposomes containing lipophilic muramyl tripeptide. Cancer Research 1983; 43: 2010–2014
   PubMed Web of Science ®Google Scholar
• Kleinerman E.S., Murray J.L., Snyder J.S., Cunningham J.E., Fidler I.J. Activation of tumoricidal properties of monocytes from cancer patients following intravenous administration of liposomes containing muramyl tripeptide phosphatidylethanolamine. Cancer Research 1989; 49: 4665–4670
   PubMed Web of Science ®Google Scholar
• Koff W.C., Showalter S.D., Hampar B., Fidler I.J. Protection of mice against fatal herpes simplex type 2 infection by liposomes containing muramyl tripeptide. Science 1985; 228: 295–297
   Google Scholar
• Laver J., Abboud M., Warren D., Gillio A., Martin D., O'Relly R.J., Moore M.A.S. Hemotological effects of IL-1 following myelosuppressive chemoradiotherapy. Lymphokine Receptor Interactions, D. Fradelizi, J. Bertoglio. Colloque INSERM/John Libbey Eurotext, Paris 1989; 219–227, In
   Google Scholar
• Maeda M., Knowles R.D., Kleinerman E.S. Muramyl tripeptide phosphatidylethanolamine encapsulated in liposomes stimulates monocyte production of tumor necrosis factor and interleukin-1 in vitro. Cancer Communications 1991; 3: 313–321
   PubMed Web of Science ®Google Scholar
• Meijne E.I.M., van der Winder-van Groenewegen R.J.M., Ploemacher R.E., Vos O., David J.A.G., Huiskamp R. The effects of X-irradiation on hematopoietic stem cell compartments in the mouse. Experimental Hematology 1991; 19: 617–623
   PubMed Web of Science ®Google Scholar
• Melissen P.M.B., van Vianen W., Rijsbergen Y., Bakker-Woudenberg I.A.J.M. Free versus liposome-encapsulated muramyl tripeptide phosphatidylethanolamine in treatment of experimental Klebsiella pneumoniae infection. Infection and Immunity 1992; 60: 95–101
   PubMed Web of Science ®Google Scholar
• Morrissey P., Charrier K., Bressler L., Alpert A. The influence of IL-1 treatment on the reconstitution of the hemopoietic and immune systems after sublethal radiation. Journal of Immunology 1988; 140: 4204–4210
   PubMed Web of Science ®Google Scholar
• Murray J.L., Kleinerman E.S., Cunningham J.E., Tatom J.R., Anderjcio K., Lepe-Zuniga J., Lamki L.M., Rosenblum M.G., Frost H., Gutterman J.U., Fidler I.J., Krakoff I.H. Phase I trial of liposomal muramyl tripeptide phosphatidylethanolamine in cancer patients. Journal of Clinical Oncology 1989; 7: 1915–1925
   PubMed Web of Science ®Google Scholar
• Neta R. In vivo effects and interactions of recombinant interleukin 1 and tumor necrosis factor in radio-protection and in induction of fibrinogen. Tumor Necrosis Factor/Cachectin and Related Cytokines, J. Bonavida, J. Gifford, H. Kirchner, D. Old. Karger, Basel 1988a; 246–251, In
   Google Scholar
• Neta R. Cytokines in radioprotection and therapy of radiation injury. Biotherapy 1988b; 1: 41–45
   PubMedGoogle Scholar
• Neta R., Douches S., Oppenheim J.J. Interleukin 1 is a radioprotector. Journal of Immunology 1986; 136: 2483–2485
   PubMed Web of Science ®Google Scholar
• Neta R., Oppenheim J.J., Douches S.D. Interdependence of the radioprotective effects of human recombinant interleukin 1, tumor necrosis factor, granulocyte colony stimulating factor, and murine recombinant granulocyte-macrophage colony-stimulating factor. Journal of Immunology 1988b; 140: 108–111
   PubMed Web of Science ®Google Scholar
• Neta R., Sztein M.B., Oppenheim J.J., Gillis S., Douches S.D. The in vivo effects of interleukin 1. I. Bone marrow cells are induced to cycle after administration of interleukin 1. Journal of Immunology 1987; 139: 1861–1866
   PubMed Web of Science ®Google Scholar
• Neta R., Vogel S.N., Sipe J.D., Wong G.G., Nordan R.P. Comparison of in vivo effects of human recombinant IL 1 and human recombinant IL 6 in mice. Lymphokine Research 1988a; 7: 403–412
   PubMedGoogle Scholar
• Nishiguchi I., Furuta Y., Hunter N., Murray D., Milas L. Radioprotection of hematopoietic tissue in mice by indomethacin. Radiation Research 1990; 122: 188–192
   PubMed Web of Science ®Google Scholar
• Patchen M.L., Chirigos M.A., Brook I. Use of glucan-P and sixteen other immunopharmaceutical agents in prevention of acute radiation injury. Comments on Toxicology 1988; 2: 217–231
   Google Scholar
• Patchen M.L., MacVittie T.J., Williams J.L., Schwartz G.N., Souza L.M. Administration of interleukin-6 stimulates multilineage hematopoiesis and acelerates recovery from radiation-induced hematopoietic depression. Blood 1991; 77: 472–480
   PubMed Web of Science ®Google Scholar
• Ploemacher R.E., van Os R., van Beurden C.A.J., Down J.D. Murine haemopoietic stem cells with long-term engraftment and marrow repopulating ability are more resistant to gamma-radiation than are spleen colony forming cells. International Journal of Radiation Biology 1992; 61: 489–499
   PubMed Web of Science ®Google Scholar
• Roman V., Bocquier F., Leterrier F., Fatome M. Action radioprotective de la cystéamine incorporée dans des liposomes administrés par voie orale a la souris. Comptes Rendus Académie des Sciences, Paris, Ser. III 1982; 295: 191–193
   Google Scholar
• Richardson E.C., Alving C.R. Radioprotective effects of lipid A, liposomes, and liposomes containing lipid A in mice. Biochimica et Biophysica Acta 1987; 903: 519–524
   Google Scholar
• Schumann G. Biological activities of a lipophilic muramylpeptide (MTP-PE). Immunostimulants: Now and Tomorrow, I. Azuma, G. Jollés. Japan Science Society, Tokyo 1987; 71–77, In
   Google Scholar
• Schumann G., van Hoogevest P., Fankhauser P., Probst A., Peil A., Court M., Schaffner J.C., Fischer M., Skripsky T., Graepel P. Comparison of free and liposomal MTP-PE: pharmacological, toxicologal and pharmacokinetic aspects. Liposomes in the Therapy of Infectious Diseases and Cancer, G. Lopez-Berestein, I.J. Fidler. Liss, New York 1989; 191–203, In
   Google Scholar
• Schwartz G.N., MacVittie T.J., Vigneulle R.M., Patchen M.L., Douches S.D., Oppenheim J.J., Neta R. Enhanced hematopoietic recovery in irradiated mice pretreated with interleukin-1 (IL-1). Immunopharmacology and Immunotoxicology 1987; 9: 371–389
   PubMed Web of Science ®Google Scholar
• Schwartz G.N., Patchen M.L., Neta R., MacVittie T.J. Radioprotection of mice with interleukin-1: relationship to the number of spleen colony-forming units. Radiation Research 1989; 119: 101–112
   PubMed Web of Science ®Google Scholar
• Sinclair W.K., Morton R.A. X-ray sensitivity during the cell generation cycle of cultured chinese hamster cells. Radiation Research 1966; 29: 450–474
   PubMed Web of Science ®Google Scholar
• Slordal L., Warren D.J., Moore M.A.S. Effect of recombinant murine tumor necrosis factor on hemopoietic reconstitution in sublethally irradiated mice. Journal of Immunology 1989; 142: 833–835
   PubMed Web of Science ®Google Scholar
• Sone S. Human monocyte activation to the tumoricidal state by liposome-encapsulated muramyl tripeptide and its therapeutic implication. Liposomes in the Therapy of Infectious Diseases and Cancer, G. Lopez-Berestein, I.J. Fidler. Liss, New York 1989; 125–134, In
   Google Scholar
• Swenson C.E., Popescu M.C., Ginsberg R.S. Preparation and use of liposomes in the treatment of microbial infections. Critical Reviews in Microbiology 1988; 15(1)S1–S31
   Google Scholar
• Till J.E., McCulloch E.A. A direct measurement of the radiation sensitivity of normal bone marrow cells. Radiation Research 1961; 14: 213–222
   PubMed Web of Science ®Google Scholar
• Till J.E., McCulloch E.A. Early repair process in marrow cells irradiated and proliferating in vivo. Radiation Research 1963; 18: 96–101
   PubMed Web of Science ®Google Scholar
• Thornalley P.J., Vajak M. Possible role for metallothionein in protection against radiation induced oxidative stress. Kinetics and mechanisms of its reaction with superoxide and hydroxyl radicals. Biochimica et Biophysica Acta 1985; 827: 36–44
   PubMed Web of Science ®Google Scholar
• Vacek A., Michurina T.V., Serova L.V., Rotkovská D., Bartoníčková A. Decrease in the number of progenitors of erythrocytes (BFUe, CFUe), granulocytes and macrophages (GM-CFC) in bone marrow of rats after a 14-day flight onboard the Cosmos-2044 biosatellite. Folia Biologica (Praha) 1991; 37: 35–41
   Google Scholar
• Wachsmuth E.D., Huber J. Stimulant effect of the immunomodulator MTP-PE on proliferation of monocytic cells in the guinea pig. Virchows Archiv B Cell Pathology 1989; 58: 45–57
   Google Scholar
• Walden T.L., Jr., Patchen M.L., MacVittie T.J. Leukotriene-induced radioprotection of hematopoietic stem cells in mice. Radiation Research 1988; 113: 388–395
   PubMed Web of Science ®Google Scholar
• Weinstein J.N., Leserman L.D. Liposomes as drug carriers in cancer chemotherapy. Pharmacology and Therapeutics 1984; 24: 207–233
   PubMed Web of Science ®Google Scholar
• Wuest B., Wachsmuth E.D. Stimulatory effect of N-acetyl muramyl dipeptide in vivo: proliferation of bone marrow progenitor cells in mice. Infection and Immunity 1982; 37: 452–462
   Google Scholar