DNA Double-strand Breaks Induced by Low Energy Protons in V79 Cells

References

• Ahnström G., Bryant P.E. DNA double-strand breaks generated by the repair of X-ray damage in Chinese hamster cells. International Journal of Radiation Biology 1982; 41: 671–676
   Web of Science ®Google Scholar
• Aufderheide E., Rink H., Hieber L., Kraft G. Heavy ion effects on cellular DNA: strand breaks induction and repair in cultured diploid lens epithelial cells. International Journal of Radiation Biology 1987; 51: 779–790
   Web of Science ®Google Scholar
• Belli M., Cera F., Cherubini R., Goodhead D.T., Haque A.M.I., Ianzini F., Moschini G., Nikjio H., Sapora O., Simone G., Stevens D.L., Tabocchini M.A., Tiveron P. Inactivation induced by deuterons of various LET in V79 cells. Radiation Protection Dosimetry 1994; 52: 305–310
   Web of Science ®Google Scholar
• Belli M., Cera F., Cherubini R., Haque A.M.I., Ianzini F., Moschini G., Sapora O., Simone G., Tabocchini M.A., Tiveron P. Inactivation and mutation induction in V79 cells by low energy protons: re-evaluation of the results at the LNL facility. International Journal of Radiation Biology 1993; 63: 331–337
   PubMed Web of Science ®Google Scholar
• Belli M., Cera F., Cherubini R., Ianzini F., Moschini G., Sapora O., Simone G., Tabocchini M.A., Tiveron P. Mutation induction and RBE-LET relationship of low energy protons in V79 cells. International Journal of Radiation Biology 1991; 59: 459–465
   PubMed Web of Science ®Google Scholar
• Belli M., Cera F., Cherubini R., Ianzini F., Moschini G., Sapora O., Simone G., Tabocchini M.A., Tiveron P. RBE-LET relationship for survival and mutation induction of V79 cells irradiated with low energy protons: re-evaluation of the LET values at the LNL facility. International Journal of Radiation Biology 1992a; 61: 145–146
   Web of Science ®Google Scholar
• Belli M., Cherubini R., Finotto S., Moschini G., Sapora O., Simone G., Tabocchini M.A. RBE-LET relationship for the survival of V79 cells irradiated with low energy protons. International Journal of Radiation Biology 1989; 55: 93–104
   PubMed Web of Science ®Google Scholar
• Belli M., Cherubini R., Galeazzi G., Mazzucato S., Moschini G., Sapora O., Simone G., Tabocchini M.A. Proton irradiation facility for radiobiological studies at a 7MV Van de Graaff accelerator. Nuclear Instruments and Methods in Physics Research, A 1987; 256: 576–580
   Web of Science ®Google Scholar
• Belli M., Goodhead D.T., Ianzini F., Simone G., Tabocchini M.A. Direct comparison of biological effectiveness of protons and α-particles of the same LET. II. Mutation induction at the HPRT locus in V79 cells. International Journal of Radiation Biology 1992b; 61: 625–629
   PubMed Web of Science ®Google Scholar
• Blöcher D. DNA double-strand breaks in Ehrlich ascites tumour cells at low doses of X-rays. I. Determination of induced breaks by centrifugation at reduced speed. International Journal of Radiation Biology 1982; 42: 317–328
   Web of Science ®Google Scholar
• Blöcher D. DNA double-strand break repair determines the RBE of α-particles. International Journal of Radiation Biology 1988; 54: 761–777
   PubMed Web of Science ®Google Scholar
• Bryant P.E. Enzymatic restriction of mammalian cell DNA using PvuII and Bam HI: evidence for the double-strand break origin of chromosomal aberrations. International Journal of Radiation Biology 1984; 46: 57–65
   Web of Science ®Google Scholar
• Bryant P.E. Enzymatic restriction of mammalian cell DNA: evidence for double-strand breaks as potentially lethal lesions. International Journal of Radiation Biology 1985; 48: 55–60
   Web of Science ®Google Scholar
• Bryant P.E. Use of restriction endonucleases to study relationships between DNA double-strand breaks, chromosomal aberrations and other end-points in mammalian cells. International Journal of Radiation Biology 1988; 54: 869–890
   PubMed Web of Science ®Google Scholar
• Bryant P.E. Restriction endonuclease and radiation-induced DNA double-strand breaks and chromosomal aberrations: similarity and differences. Chromosomal Aberrations: Basic and Applied Aspects, G. Obe, A.T. Natarayan. Springer-Verlag, Berlin 1989; 61–69, In
   Google Scholar
• Chadwick K.H., Leenhouts H.P. The Molecular Theory of Radiation Biology. Springer-Verlag, Berlin 1981
   Google Scholar
• Charlton D.E., Nikjio H., Humm J.L. Calculation of initial yields of single- and double-strand breaks in cell nuclei from electrons, protons and α-particles. International Journal of Radiation Biology 1989; 56: 1–19
   PubMed Web of Science ®Google Scholar
• Cole A., Meyn R.E., Chen R. A relative contribution of unrepaired single-strand and double-strand DNA breaks to biological damage. Biophysical Journal 1979; 25: 155a–155a
   Google Scholar
• Folkard M., Prise K.M., Vojnovic D.S., Roper M.J., Michael B.D. The irradiation of V79 cells by protons with energy below 2 MeV. Part I. Experimental arrangement and measurement of cell survival. International Journal of Radiation Biology 1989; 56: 221–237
   PubMed Web of Science ®Google Scholar
• Fox R.A. The analysis of single-strand breaks in E. coli using a curve-fitting procedure. International Journal of Radiation Biology 1976; 30: 67–78
   Web of Science ®Google Scholar
• Frankenberg D., Frankenberg-Schwager M., Blöcher D., Adamczyk C. Initial and irreparable double-strand breaks in the DNA of irradiated eukaryotic cells in dependence of dose-rate and LET; implications for survival studies. Proceedings of the 7th Symposium on Microdosimetry, J. Booz, H.G. Ebert, H.D. Hartfield. Harwood, London 1981; 1033–1042
   Google Scholar
• Frankenberg D., Frankenberg-Schwager M., Harbich R. Interpretation of the shape of survival curves in terms of induction and repair/misrepair of DNA double-strand breaks. British Journal of Cancer 1984; 49(VI)233–238
   Google Scholar
• Goodhead D.T. Relationship of microdosimetric techniques to applications in biological systems. Dosimetry of Ionizing Radiation, K.R. Kase, B.E. Bjarngaard, F.M. Attix. Academic, Orlando 1987; 2: 1–89, In
   Google Scholar
• Goodhead D.T. The initial physical damage produced by ionizing radiations. International Journal of Radiation Biology 1989; 56: 623–634
   PubMed Web of Science ®Google Scholar
• Goodhead D.T., Belli M., Mills A.J., Bance D.A., Allen L.A., Hall S.C., Lanzini F., Simone G., Stevens D.L., Stretch A., Tabocchini M.A., Wilkinson R.E. Direct comparison between protons and α-particles of the same LET. I. Irradiation methods and inactivation of asynchronous V79, HeLa and C3H10T1/2 cells. International Journal of Radiation Biology 1992; 61: 611–624
   PubMed Web of Science ®Google Scholar
• Goodhead D.T., Nikjio H. Track structure analysis of ultrasoft X-rays compared to high- and low-LET radiations. International Journal of Radiation Biology 1989; 55: 513–529
   PubMed Web of Science ®Google Scholar
• Hamm R.N., Turner J.E. Model calculations of radiation-induced DNA damage. Biophysical Modelling of Radiation Effects, K.H. Chadwick, G. Moschini, M.N. Varma. Adam Hilger, Bristol 1992; 53–60, In
   Google Scholar
• Henner W.D., Grunberg S.M., Haseltine W.A. Enzyme action at 3′ termini of ionizing radiation-indced DNA strand breaks. Journal of Biological Chemistry 1983; 258: 15198–15205
   PubMed Web of Science ®Google Scholar
• Jenner T.J., Belli M., Goodhead D.T., Ianzini F., Simone G., Tabocchini M.A. Direct comparison of biological effectiveness of protons and α-particles of the same LET. III. Initial yield of DNA double-strand breaks in V79 cells. International Journal of Radiation Biology 1992; 61: 631–637
   PubMed Web of Science ®Google Scholar
• Jenner T.J., deLara C.M., O'Neill P., Stevens D.L. The induction and rejoining of DNA double-strand breaks in V79-4 mammalian cells by γ- and α-irradiation. International Journal of Radiation Biology 1993; 64: 265–273
   PubMed Web of Science ®Google Scholar
• Jenner T.J., Sapora O., O'Neill P., Fielden E.M. Eahancement of DNA damage in mammalian cells upon bioreduction of the nitroimidazole-aziridines RSU-1069 and RSU-1131. Biochemical Pharmacology 1988; 37: 3837–3842
   PubMed Web of Science ®Google Scholar
• Kampf G., Eichhorn K. DNA strand breakage by different radiation qualities and relations to cell killing: further results after the influence of α-particles and carbon ions. Studia Biophysica 1983; 93: 17–26
   Google Scholar
• Litwin S. Distribution of radioactive recovery in randomly cut sediment DNA. Journal of Applied Probability 1969; 6: 275–284
   Web of Science ®Google Scholar
• Michalik V. Particle track structure and its correlation with radiobiological endpoint. Physics in Medicine and Biology 1991; 36: 1001–1012
   PubMed Web of Science ®Google Scholar
• Millar B.C., Sapora O., Fielden E.M., Loverock P.S. The application of rapid-lysis techniques in radiobiology. IV. The effect of glycerol and DMSO on Chinese hamster cell survival and DNA single-strand break production. Radiation Research 1981; 86: 506–514
   PubMed Web of Science ®Google Scholar
• Natarajan A.T., Obe G., von Zeeland A.A., Palitti F., Mejers M., VerdegaalImmerzell E.A.M. Molecular mechanisms involved in the production of chromosomal aberrations. II. Utilization of Neurospora endonuclease for the study of aberrations production by X-rays in G1 and G2 stages of the cell cycle. Mutation Research 1980; 69: 293–305
   PubMed Web of Science ®Google Scholar
• Okayasu R., Iliakis G. Linear DNA elution dose response curves obtained in CHO cells with non-unwinding filter elution after appropriate selection of the lysis conditions. International Journal of Radiation Biology 1989; 55: 569–581
   PubMed Web of Science ®Google Scholar
• Prise K.M., Folkard M., Davies S., Michael B.D. The irradiation of V79 mammalian cells by protons with energy below 2 MeV. Part II. Measurement of oxygen enhancement ratio and DNA damage. International Journal of Radiation Biology 1990; 58: 261–277
   PubMed Web of Science ®Google Scholar
• Radford I.R. Effect of radiomodifying agents on the ratio of X-ray induced lesions in cellular DNA: use in lethal lesion determination. International Journal of Radiation Biology 1986; 49: 621–637
   Web of Science ®Google Scholar
• Raju M.R., Carpenter S.G., Chmielewski J.J., Schillaci M.E., Wilder M.E., Freyer J.P., Johnson N.F., Schor P.L., Sebring R.J., Goodhead D.T. Radiobiology of ultrasoft X-rays. I. Cultured hamster cells (V79). Radiation Research 1987; 110: 396–412
   PubMed Web of Science ®Google Scholar
• Roots R., Holley W., Chatterjee A., Irizarry M., Kraft G. The formation of strand breaks in DNA after high-LET irradiation: a comparison of data from in vitro and cellular systems. International Journal of Radiation Biology 1990; 58: 55–69
   PubMed Web of Science ®Google Scholar
• Rydberg B. DNA strand breaks induced by low-energy heavy ions. International Journal of Radiation Biology 1985; 47: 57–61
   Web of Science ®Google Scholar
• Sapora O., Barone F., Belli M., Maggi A., Quintiliani M., Tabocchini M.A. Relationships between cell killing, mutation induction and DNA damage in X-irradiated V79 cells: the influence of oxygen and DMSO. International Journal of Radiation Biology 1991; 60: 467–482
   PubMed Web of Science ®Google Scholar
• Ward J.F. DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability. Progress in Nucleic Acids Research and Molecular Biology 1988; 35: 95–125
   PubMed Web of Science ®Google Scholar
• Weber K.J., Flentje M. DNA double-strand breakage and rejoining in mammalian cells by radiations of differing LET. 24th Annual Meeting of the European Society for Radiation Biology, ErfurtGermany, October, 4–8, 1992; 26–26, (Abs).
   Google Scholar