Haematopoietic Growth Factors in the Treatment of Therapeutic and Accidental Irradiation-induced Bone Marrow Aplasia

References

• Andrew R. (1993) Biology of the c-kit ligand in haematopoiesis. Symposium on Cytokines, Science and the Therapeutic Context Current Practice, Controversies and Future Applications. 35th ASH meeting, Saint Louis, MissouriUSA, 1993, G.D. Demetri, E.J. Shpall. University of Colorado, School of Medicine, DenverColorado, USA, 8–9, In
   Google Scholar
• Andrews R.G., Bensinger W.I., Knitter G.H., Bartelmez S.H., Longin K., Bernstein I.D., Appelbaum F.R., Zsebo K.M. The Ligand for c-kit, stem cell factor, stimulates the circulation of cells that engraft lethally irradiated baboons. Blood 1992; 80: 2715–2720
   PubMed Web of Science ®Google Scholar
• Antman K.S., Griffin J.D., Elias A., Socinski M.A., Ryan L., Cannistra S.A., Oette D., Whitley M., Frei E., III, Schnipper L.E. Effect of recombinant human granulocyte-macrophage colony-stimulating factor on chemotherapy-induced myelosuppression. New England Journal of Medicine 1988; 319: 593–599
   PubMed Web of Science ®Google Scholar
• Atkinson K., Matias C., Guiffre A., Seymour R., Cooley M., Biggs J., Munro V., Gillis S. In vivo administration of granulocyte colony-stimulating factor (G-CSF) granulocyte-macrophage CSF, interleukin 1 (IL-1) and IL-4, alone and in combination, after allogeneic murine hematopoietic stem cell transplantation. Blood 1991; 77: 1376–1382
   PubMed Web of Science ®Google Scholar
• Baranov A.E. (1993) Is allogeneic bone marrow transplantation needed in case of severe uniform whole-body irradiation: experience from a recent accident (NESHWISH, Belarus) and previous accident. Second Consensus Development Conference on the Treatment of Radiation Injuries. April, 14–17. AFRRI, 67–67, Edited by: Bethesda, Bethesda, USA
   Google Scholar
• Baranov A.E., Selidovkin G.D., Butturini A., Gale R.P. Haematopoietic recovery after 10 Gy acute total-body irradiation. Blood 1994; 83: 378–384
   Web of Science ®Google Scholar
• Bender J., Maples P., Uwerzagt K., Shilling M., Williams S., Van Epps D. Expansion of neutrophilic precursor and progenitor cells in suspension culture of CD34 + cells enriched from human bone marrow. Experimental Hematology 1993; 21: 870–877
   PubMed Web of Science ®Google Scholar
• Bensinger W.I., Price T.H., Dale D.C., Appelbaum F.R., Clift R., Lilleby K., Williams B., Storb R., Thomas E.D., Buckner C.D. The effect of daily recombinant human granulocyte colony-stimulating factor administration on normal granulocyte donors undergoing. Blood 1993; 81: 1883–1888
   PubMed Web of Science ®Google Scholar
• Bettelheim P., Valent P., Andreeff M., Tafuri A., Haimi J., Gorischer C., Muhm M., Sillaber C., Haas O., Vieder L., Maurer D., Schulz G., Speiser W., Geissler K., Kier P., Hinterberger W., Lechner K. Recombinant human granulocyte-macrophage colony-stimulating factor in combination with standard induction chemotherapy in de novo acute myeloid leukemia. Blood 1991; 77: 700–711
   PubMed Web of Science ®Google Scholar
• Biesma B., de Vries E.G., Willemse P.H., Slutter W.J., Postmus P.E., Limburg P.C., Stern A.C., Vellenga E. Efficacy and tolerability of recombinant human granulocyte-macrophage colony-stimulating factor in patients with chemotherapy-related leukopenia and fever. European Journal of Cancer 1990; 26: 932–936
   PubMed Web of Science ®Google Scholar
• Bock G., Marsh J. Molecular Control of Haematopoiesis. CIBA Foundation, Symposium 148. Wiley, ChichesterEngland 1990
   Google Scholar
• Brach M.A., Devos S., Gruss H.J., Herrmann F. Prolongation of survival of human polymorphonuclear neutrophils by granulocyte-macrophage colony-stimulating factor is caused by inhibition of programmed cell death. Blood 1992; 80: 2920–2924
   PubMed Web of Science ®Google Scholar
• Bunn P.A., Crowley J., Hazuka M. The role of GM-CSF in limited stage SCLC: a randomized phase III study of the Southwest Oncology Group (SWOG). Proceedings of the American Society of Clinical Oncology 1992; 11: 974–974
   Google Scholar
• Butturini A., De Souza P.C., Gale R.P., Cordiero J.M., Lopes D.M., Neto C., Cunha C.B., De Souza C.E., Ho W.G., Tabak D.G., Sampai J.M., Burla A., The Navy Hospital Radiation Team. Use of recombinant granulocyte-macrophage colony-stimulating factor in the Brazil radiation accident. Lancet 1988; ii: 471–475
   Google Scholar
• Butturini A., Gale R. Role of haematopoietic growth factors in radiation victims. RhGM-CSF following the Goiânia accident. Treatment of Radiation Injuries, D. Browne, J.F. Weiss, J. MacVittie, M.V. Pillai. Plenum, New York 1990; 127–132, In
   Google Scholar
• Cazzola M., Ponchio L., Beguin Y., Rosti V., Bergamaschi G., Liberato N.L., Fregoni V., Nalli G., Barosi G., Ascari E. Subcutaneous erythropoietin for treatment of refractory anaemia in haematologic disorders. Results of a phase I/II clinical trial. Blood 1992; 79: 29–37
   PubMed Web of Science ®Google Scholar
• Collins C., Livingston R.B., Ellis G., Caron D. Effect of PIXY on haematopoietic recovery after high-dose cyclophosphamide (CTX) etoposide (VP-16) and cisplatin (CDDP) (CEP) in women with breast carcinoma. Blood 1993; 82: 10–10, 366a, 1447.
   Web of Science ®Google Scholar
• Crawford J., Figlin R., Chang A., Hamm J., Wasserheit C., Lee M., Champion M., Manfreda S., Isaacs R. Phase I/II trial of recombinant human interleukin-6 (rhIL-6) and granulocyte colony stimulating factor (rhG-CSF) following ifosphamide, carboplatine and etoposide (ICE) chemotherapy in patients with advanced Non Small Cell Lung Carcinoma (NSCLC). Blood 1993; 82: 10–10, 367a, 1454.
   Web of Science ®Google Scholar
• Crawford J., Ozer H., Stroller R., Johnson D., Lyman G., Tabbara I., Kris M., Grous J., Picozzi V., Rausch G., Smith R., Gradishar W., Yamanda A., Vincent M., Stewart M., Glaspy J. Reduction by granulocyte colony-stimulating factor of fever and neutropenia induced by chemotherapy in patients with small-cell lung cancer. New England Journal of Medicine 1991; 325: 164–170
   PubMed Web of Science ®Google Scholar
• Crown J., Jakubowski A., Kemeny N., Gordon M., Gasparetto C., Wong G., Sheridan C., Toner G., Meisenberg B., Botet J., Appelwhite J., Sinha S., Moore M., Kelsen D., Buhles W., Gabrilove J. Phase I/II trial of recombinant human interleukin-1 with and without 5-fluorouracil in patients with gastrointestinal cancer receiving 5-fluorouracil. Blood 1991; 78: 1420–1425
   PubMed Web of Science ®Google Scholar
• Dercksen M.W., Hoekman K., Ten BoekkelHuinink W.W., Rankin E., Wagstaff J., Pinedoh M. Efficacy and tolerability of rhuIL-3 for patients (pts) with small cell lung cancer (SCLC) or ovarian cancer (OV) treated with chemotherapy (CT). Proceedings of the American Society of Clinical Oncology 1992; 11: 1020–1020
   Google Scholar
• De Vries E.G., Biesma B., Willemse P.H., Mulder N.H., Stern A.C., Aalders J.G., Vellenga E. A double blind placebo controlled study with granulocyte-macrophage colony-stimulating factor during chemotherapy for ovarian carcinoma. Cancer Research 1991; 51: 116–122
   PubMed Web of Science ®Google Scholar
• Du X.X., Keller D., Maze R., Williams D.A. Comparative effects of in vivo treatment using interleukin 11 and stem cell factor on reconstitution in mice after bone marrow transplantation. Blood 1993; 82: 1016–1022
   PubMed Web of Science ®Google Scholar
• Eschbach J.W., Kelly M.R., Haley N.R., Abels R.I., Adamson J.W. Treatment of the anemia of progressive renal failure with recombinant human erythropoietin. New England Journal of Medicine 1989; 321: 158–163
   PubMed Web of Science ®Google Scholar
• Estey E., Thall P.F., Kantarjian H., O'Brien S., Koller C.A., Beran M., Gutterman J., Deisseroth A., Keating M. Treatment of newly diagnosed acute myelogenous leukemia with granulocyte-macrophage colony-stimulating factor (GM-CSF) before and during continuous infusion high dose ara-C + daunorubicin: comparison to patients treated without GM-CSF. Blood 1992; 79: 2246–2255
   PubMed Web of Science ®Google Scholar
• Fao P. Erythropoietin: clinical applications. Acta Hematologica 1991; 86: 162–168
   PubMed Web of Science ®Google Scholar
• Fushiki M., Abe M. Randomized double blinded controlled study of rHG-CSF in patients with neutropenia induced by radiation therapy. Proceedings of the American Society of Clinical Oncology 1992; 11: 1437–1437
   Google Scholar
• Gabrielove J.L., Jakubowski A., Scher H., Sternberg C., Wong G., Grous J., Yagoda A., Fain K., Moore M.A., Clarkson B., Oettgen H., Alton K., Welte K., Souza L. Effect of granulocyte colony stimulating factor on neutropenia and associated morbidity due to chemotherapy for transitional-cell carcinoma of the urothelium. New England Journal of Medicine 1988; 318: 1414–1422
   PubMed Web of Science ®Google Scholar
• Ganem G., Solal-Celigny P. Utilisation en thérapeutique des facteurs de croissance hématopoïétiques. Edition Techniques Encyclopédie Médico-Chirurgicale (Paris, France). Hématologie 1993; 7–7, 13 070-A-10
   Google Scholar
• Ganser A., Seipelt G., Hoelzer D. The role of GM-CSF, G-CSF, Interleukin 3 and erythropoietin in myelodysplastic syndromes. American Journal of Clinical Oncology (CCT) 1991; 14(Suppl. 1)S34–S39
   Google Scholar
• Ganser A., Seipelt G., Lindemann A., Ottmann O.G., Falk S., Eder M., Herrmann F., Becher R., Hoffken K., Büchner T., Klausmann M., Frisch J., Schluz G., Mertelsmann R., Hoelzer D. Effects of recombinant human interleukin 3 in patients with myelodysplastic syndromes. Blood 1990; 76: 455–462
   PubMed Web of Science ®Google Scholar
• Gianni A.M., Siena S., Bregni M., Tarella C., Stern A.C., Pileri A., Bonadonna G. Granulocytemacrophage colony-stimulating factor to harvest circulating haematopoietic stem cells for autotransplantation. Lancet 1989; ii: 580–585
   Google Scholar
• Glaspy J., Bleeker G., Crawford J., Stoller R., Strauss M. The impact of therapy with filigrastim (recombinant granulocyte colony stimulating factor) on the health care cost associated with cancer chemotherapy. European Journal of Cancer 1993; 29 A(suppl. 7)S23–S30
   Google Scholar
• Gordon M.S., Sledge G.W., Battiato L., Breeden E., Cooper R., McCaskill-Stevens W., Kuca B., Kaye J., Hoffman R. The in vivo effects of subcutaneously (SC) administered recombinant human interleukin 11 (Neumega™ rhIL-11 growth factor, rhIL-11) in women with breast cancer (BC). Blood 1993; 82(10)498a–498a, 1976
   Web of Science ®Google Scholar
• Gorin N.C., Coiffier B., Hayat M., Fouillard L., Kuentz M., Flesch M., Colombat P., Boivin P., Slavin S., Philip T. Recombinant human granulocytemacrophage colony-stimulating factor after high-dose chemotherapy and autologous bone marrow transplantation with unpurged and purged marrow in non-Hodgkin's lymphoma: a double bline placebo control trial. Blood 1992; 80: 1149–1157
   PubMed Web of Science ®Google Scholar
• Greenberg P.L., Negrin R., Nagler A. The use of haematopoietic growth factors in the treatment myelodysplastic syndromes. Cancer Survey 1990; 9: 199–212
   PubMedGoogle Scholar
• Haylock D.N., To L.B., Dowse T.L., Juttner C.A., Simmons P.J. Ex vivo expansion and maturation of peripheral blood CD34+ cells into the myeloid lineage. Blood 1992; 80: 1405–1412
   PubMed Web of Science ®Google Scholar
• Hermann F., Lindemann A., Klien H., Lubbert M., Schultz G., Mertelsmann R. Effect of recombinant granulocyte-macrophage colony-stimulating factor in patients with myelodysplastic syndrome with excess blasts. Leukemia 1989; 5: 335–338
   Google Scholar
• Herodin F., Mestries J.C., Janodet D., Martin S., Mathieu J., Gascon M.P., Pernin M.O., Ythier A. Recombinant glycosylated human interleukin 6 accelerates peripheral blood platelet count recovery in radiation induced bone marrow depression in baboons. Blood 1992; 80: 688–695
   PubMed Web of Science ®Google Scholar
• Hervatin F., Leniger C., Thierry D., Traineau R., Benbunan M., Carosela E., Gluckman E. Enrichment of cord blood and bone marrow CD34+ cells. Experimental Hematology 1993; 21: 1068–1068
   Google Scholar
• IAEA. The Radiological Accident in Goiânia. International Atomic Energy Agency, Vienna 1988, STI/PUB/815
   Google Scholar
• IAEA. The Radiological Accident in San Salvador. International Atomic Energy Agency, Vienna 1990, STI/PUB/847
   Google Scholar
• IAEA. The Radiological Accident in Soreq. International Atomic Energy Agency, Vienna 1993, STI/PUB/925
   Google Scholar
• Iizumi T., Sato S., Iiyama T., Hata R., Amemiy H., Tomomasa H., Yasaki T., Umeda T. Recombinant human interleukin 1 beta-analogue as a regulator of haematopoiesis in patients receiving chemotherapy for urogenital cancers. Cancer 1991; 68: 1520–1523
   PubMed Web of Science ®Google Scholar
• Jonsson B., Karlsson G. Outcome measurement in economic evaluations of growth factors. European Journal of Cancer 1993; 29A(Suppl. 7)S19–S22
   Google Scholar
• Kojima S., Fukuda M., Miyajima Y., Matsuyama T., Horibe K. Treatment of aplastic anemia in children with recombinant human granulocyte colony-stimulating factor. Blood 1991; 77: 937–941
   PubMed Web of Science ®Google Scholar
• Koller M.R., Emerson S.G., Palsson B.O. Large-scale expansion of human stem and progenitor cells from bone marrow mononuclear cells in continuous perfusion cultures. Blood 1993; 82: 378–384
   PubMed Web of Science ®Google Scholar
• Kotake T., Miki T., Akaza H., Kubota Y., Nishio Y., Matsumura Y., Ota K., Ogawa N. Effect of recombinant granulocyte colony-stimulating factor (rG-CSF) on chemotherapy-induced neutropenia in patients with urogenital cancer. Cancer Chemotherapy and Pharmacology 1991; 27: 253–257
   PubMed Web of Science ®Google Scholar
• Kurzrock R., Talpaz M., Estrov Z., Rosenblum M.G., Gutterman J.R. Phase I study of recombinant human interleukin 3 in patients with bone marrow failure. Journal of Clinical Oncology 1991; 9: 1241–1250
   PubMed Web of Science ®Google Scholar
• Lapidot T., Pflumio F., Doedens M., Murdoch B., Williams D.E., Dick J.E. Cytokine stimulation of multilineage haematopoiesis from immature human cells engrafted in SCID mice. Science 1992; 255: 1137–1141
   PubMed Web of Science ®Google Scholar
• Laporte J.P., Fouillard L., Douay L., Eugene-Jolchine I., Isnard F., Stachowiak J., Najman A., Gorin N.C. GM-CSF instead of autologous bone-marrow transplantation after the BEAM regimen. Lancet 1991; 338: 601–602
   PubMed Web of Science ®Google Scholar
• Leary A., Wong G., Clark S., Smith A.G., Ogawa M. Leukemia inhibitory factor differentiation-inhibiting activity/human interleukin for DA cells augments proliferation of human haematopoietic stem cells. Blood 1990; 75: 1960–1964
   PubMed Web of Science ®Google Scholar
• Lecorroler A.G., Moatti J.P., Detrounay B., Fagani C., Blaise D., Maraninchi D. L'évaluation des facteurs de croissance hématopoïétiques (FCH): de la minimisation des coûts à une véritable analyse économique. Cahier d'Oncologie 1993; 2: 267–273
   Google Scholar
• Lieschke G.J., Burgess A.W. Granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor. New England Journal of Medicine 1992; 327(1)28–35, (2), 99–106.
   PubMed Web of Science ®Google Scholar
• Lindeman A., Ganser A., Hermann F., Frisch J., Siepelt G., Schulz G., Hoelzer D., Elsman R. Biologic effects of recombinant human interleukin 3 in vivo. Journal Clinical Oncology 1991; 9: 2120–2127
   PubMed Web of Science ®Google Scholar
• Logothetis C.J., Dexeus F.H., Sella A., Amato R.J., Kilbourn R.G., Finn L., Gutterman J.U. Escalated therapy for refractory urothelial tumours: methotrexate-vinblastine-doxorubicin-cisplatin plus unglycosilated recombinant human granulocyte-macrophage colony-stimulating factor. Journal of the National Cancer Institute 1990; 82: 667–672
   PubMed Web of Science ®Google Scholar
• Luikart S., MacDonald M., Herzan D., Modeas C., Goutsou M., Clamon G., Maurer H., Perry M.C., Green M.R. Ability of twice daily granulocyte-macrophage colony-stimulating factor (GM-CSF) to support dose escalation of etoposide (VP-16) and carboplatin (CBDCA) in extensive small cell lung cancer (SCLC). Proceedings of the American Society of Clinical Oncology 1991; 10: 242–242, 825a.
   Google Scholar
• Lyman G.H., Lyman C.G., Sanderson R.A., Balducci L. Decision analysis of haematopoietic growth factor use in patients receiving cancer chemotherapy. Journal of the National Cancer Institute 1993; 85: 488–493
   PubMed Web of Science ®Google Scholar
• MacVittie T.J., Monroy R.L., Patchen M.L., Souza L.M. therapeutic use of recombinant human G-CSF (rhG-CSF) in a canine model of sublethal and lethal whole-body irradiation. International Journal of Radiation Biology 1990; 57: 723–736
   PubMed Web of Science ®Google Scholar
• MacVittie T.J., Monroy R., Vigneulle R.M., Zeman G.H., Jackson W.E. The relative biological effectiveness of mixed fission-neutron-γ-radiation on the haematopoietic syndrome in the canine: effect of therapy on survival. Radiation Research 1991; 128: 529–536, (Suppl.)
   Web of Science ®Google Scholar
• Mayani H., Dragowska W., Landsorp P.M. Cytokine-induced selective expansion and maturation of erythroid versus myeloid progenitors from purified cord blood precursor cells. Blood 1993; 12: 3252–3258
   Google Scholar
• Miura N., Okada S., Zsebo K.M., Miura Y., Suda T. Rat stem cell factor and IL-6 preferentially support the proliferation of c-kit-positive murine haematopoietic cells rather than their differentiation. Experimental Hematology 1993; 21: 143–149
   PubMed Web of Science ®Google Scholar
• Momin F., Kraut M., Lattin P., Valdivieso M. Thrombocytopenia in patients receiving chemoradiotherapy and G-SCF for locally advanced non small cell lung cancer. Proceedings of the American Society of Clinical Oncology 1992; 11: 983–983
   Google Scholar
• Monroy R., Skelly S., Davis T., MacVittie J. Therapeutic evaluation of interleukin 1 for stimulation of haematopoiesis in primates after autologous bone marrow transplantation. Biotherapy 1992; 4: 97–108
   PubMedGoogle Scholar
• Muench M.O., Firpo P.T., Moore M. Bone marrow transplantation with interleukin 1 plus Kit Ligand ex vivo expanded bone marrow accelerates haematopoietic reconstitution in mice without the loss of stem cell lineage and proliferative potential. Blood 1993; 81: 3463–3473
   PubMed Web of Science ®Google Scholar
• Muench M.O., Moore M. Accelerated recovery of peripheral blood cell counts in mice transplanted with in vitro cytokine expanded haematopoietic progenitors. Experimental Hematology 1992; 20: 611–615
   PubMed Web of Science ®Google Scholar
• Nemunaitis J., Anasetti C., Storb R., Bianco J.A., Buckner C.D., Onetto N., Martin P., Sander J., Sullivan K., Mori M., Shannon-Dorcy K., Bowden R., Appelbaum F., Hansen J., Singer J.W. Phase II trial of recombinant human granulocyte-macrophage colony-stimulating factor in patients undergoing allogenic bone marrow transplantation from unrelated donors. Blood 1992; 79: 2572–2577
   PubMed Web of Science ®Google Scholar
• Nemunaitis J., Buckner C.D., Appelbaum F.R., Higano C.S., Mori M., Bianco J., Epstein C., Lipani J., Hansen J., Storb R., Thomas E.D., Appelbaum F.R. Phase I-II trial of recombinant human granulocyte-macrophage colony-stimulating factor following allogenic bone marrow transplantation. Blood 1991b; 77: 2065–2071
   PubMed Web of Science ®Google Scholar
• Nemunaitis J., Rabinowe S.N., Singer J.W., Bierman P.J., Vose J.M., Freedman A.S., Onetto N., Gillis S., Oette D., Gold M., Buchner C.D., Hansen S.A., Appelbaum F.R., Armitage J.O., Naoler L.M. Recombinant human granulocyte-macrophage colony-stimulating factor after autologous bone marrow transplantation for lymphoid cancer. New England Journal of Medicine 1991 a; 324: 1773–1778
   PubMed Web of Science ®Google Scholar
• Nemunaitis J., Shannon-Dorcy K., Appelbaum F.R., Meyers J., Owens A., Day R., Ando D., O'Neil C., Buckner D., Singer J. Long-term follow-up of patients with invasive fungal disease who received adjunctive therapy with recombinant human macrophage colony-stimulating factor. Blood 1993; 82: 1422–1427
   PubMed Web of Science ®Google Scholar
• Nemunaitis J., Singer J.W., Buckner C.D., Durnam D., Epstein C., Hill R., Storb R., Thomas E.D., Appelbaum F.R. Use of human recombinant granulocyte-macrophage colony-stimulating factor in graft failure after bone marrow transplantation. Blood 1990; 76: 245–253
   PubMed Web of Science ®Google Scholar
• Ohno R., Tomonaga M., Kobayashi T., Kanamaru A., Shirakawa S., Masaoka T., Omine M., Oh H., Nomura T., Sakai Y., Irano M., Yokomaku S., Nakayama S., Yoshida Y., Miura A., Morishima Y., Dohy H., Niho Y., Hamajima N., Takaku F. Effect of granulocyte colony-stimulating factor after intensive induction therapy in relapsed or refractory acute leukemia. New England Journal of Medicine 1990; 323: 871–877
   PubMed Web of Science ®Google Scholar
• Oster W., Frisch J., Nicolay U., Schulz G. Interleukin 3 biological effects and clinical impact. Cancer 1991; 67: 2712–2717
   PubMed Web of Science ®Google Scholar
• Parmentier C., Biquard J.M. Les facteurs régulateurs de l'hématopoïèse. La Revue du Praticien 1992; 42: 2203–2206
   PubMedGoogle Scholar
• Patchen M.L., Fischer R., MacVittie T.J. Effects of combined administration of interleukin-6 and granulocyte colony-stimulating factor on recovery from radiation-induced haemopoietic aplasia. Experimental Hematology 1993; 21: 338–344
   PubMed Web of Science ®Google Scholar
• Patchen M., MacVittie T.J., Souza L.M. Postirradiation treatment with granulocyte colony-stimulating factor and pre-irradiation WR-2721 administration synergize to enhance haemopoietic reconstitution and increase survival. International Journal of Radiation, Oncology, Biology and Physics 1992; 22: 773–779
   PubMed Web of Science ®Google Scholar
• Pettengell R., Gurney H., Radford J.A., Deakin D.P., James R., Wilkinson P.M., Kane K., Bentley J., Crowther D. Granulocyte colony stimulating factor to prevent dose-limiting neutropenia in non-Hodgkin's lymphoma: a randomized controlled trial. Blood 1992; 80: 1430–1436
   PubMed Web of Science ®Google Scholar
• Pluda J.M., Yarchoan R., Smith P.D., McAtee N., Shay L.E., Oette D., Maha M., Wahl S.M., Myers C.E., Broder S. Subcutaneous recombinant granulocytemacrophage colony-stimulating factor used as a single agent and in alternating regimen with azidothymidine in leukopenic patients with severe human immunodeficiency virus infection. Blood 1990; 76: 463–472
   PubMed Web of Science ®Google Scholar
• Powles R., Smith C., Milan S., Treleaven J., Millar J., McElwain T., Gordon-Smith E., Miliken S., Tiley C. Human recombinant GM-CSF in allogenic bone marrow transplantation for leukemia: double blind, placebo control trial. Lancet 1990; 336: 1417–1420
   PubMed Web of Science ®Google Scholar
• Ravoet C., Piccart M.J., Bron D., Kerger J., Devaleriola D., Awada A., Bleiberg H., Lips S., Dewitte M., Von Graffenried B., Chatelain C., Stryckmans P. A phase I clinical trial of recombinant human interleukin 6 (rhIL-6) in solid tumour. Proceedings of the American Association for Cancer Research 1992; 33: 1389–1389
   Google Scholar
• Ritch P.S., Schiller J., Rivkin S., Witt P.L., Grossberg S.E., Breitmeyer J.B., Drechsler D., Truitt R.L., Von Hoff D.D., Borden E.C.W. Phase I evaluation of recombinant human interleukin 6. Blood 1993; 82(10)1453–1453, 367a.
   PubMed Web of Science ®Google Scholar
• Rusthoven J.J., Eisenhauer E., Mazurka J., Hirte H., O'Connell G., Muldal A., Lu H.X., Onetto N., Swenerton K., Jeffrey J. Phase I clinical trial of recombinant human interleukin 3 combined with Carboplatin in the treatment of patients with recurrent ovarian carcinoma. Journal of National Cancer Institute 1993; 85: 80–82
   Google Scholar
• Scher H.I., Seidman A.D., Bajorin D.F., Motzer R.J., Curley T., O'Ell M., Quinlivan S., Fair W., Herr H., Sheinfeld J., Sogani P., Russo P., Dershaw D.D., Tao Y., Begg C., Bosl G.J. Escalated Methotrexate, Vinblastine, Adriamycin and Cisplatin (E-MVAC) with granulocyte colony-stimulating factor (GCSF) in urothelial cancer. Proceedings of the American Society of Clinical Oncology 1992; 11: 610–610
   Google Scholar
• Schrezenmeier H., Spath-Schwalbe E., Drechsler S., Farber L., Stromeyer P., Porzsolt F., Heimpel H., Raghavachar A. Phase I trial of interleukin 6 (IL-6) in patients with advanced renal cell carcinoma and patients with aplastic anemia (AA): effects of long-term application and differences of haemopoietic response to IL-6 in patients with normal haemopoiesis versus patients with aplastic anemia. Blood 1993; 82(10)1455–1455, 368a.
   Web of Science ®Google Scholar
• Schuening F.G., Appelbaum F.R., Deeg H.J., Sullivan-Pepe M., Graham T.C., Hackman R., Zsebo K.M., Storb R. Effects of recombinant canine stem cell factor, a c-kit ligand, and recombinant granulocyte colony-stimulating factor on haematopoietic recovery after otherwise lethal total body irradiation. Blood 1993; 81: 20–26
   PubMed Web of Science ®Google Scholar
• Sheridan W.P., Begley C.G., Juttner C.A., Szer J., To L.B., Maher D., McGrath K.M., Morstyn G., Fox R.M. Effects of peripheral blood progenitor cells mobilised by filigrastim (G-CSF) on platelet recovery after high dose chemotherapy. Lancet 1992; 339: 640–644
   PubMed Web of Science ®Google Scholar
• Srour E., Zanjani E., Brandt J., Cornetta K., Flake A.W., Hedrick K., Leemhuis T., Hoffman R. Detection of human stem cells in chimeric sheep transplantation in utero with adult human CD34+ HLA DR-bone marrow cells. Experimental Hematology 1992; 20: 746–746
   Web of Science ®Google Scholar
• Steward W.P. Granulocyte and granulocyte-macrophage colony-stimulating factors. Lancet 1993; 342: 153–157
   PubMed Web of Science ®Google Scholar
• Terstappen L.W., Buescher S., Nguyen M., Reading C. Differentiation and maturation of growth factor expanded human haematopoietic progenitors assessed by multidimensional flow cytometry. Leukemia 1992; 6: 1001–1010
   PubMed Web of Science ®Google Scholar
• Thierry D., Jullien D., Rigaud O., Hardy M., Vilcoq J.R., Magdelenat H. Human blood granulocyte macrophage progenitors (GM-CFU) during extended field radiation therapy. Acta Radiologica Oncology 1985; 24: 521–526
   PubMed Web of Science ®Google Scholar
• Tong J., Gordon M.S., Srour E.F., Cooper R.J., Orazi A., McNiece I., Hoffman R. In vivo administration of recombinant methionyl human stem cell factor expands the number of human marrow haematopoietic stem cell. Blood 1993; 82: 784–791
   PubMed Web of Science ®Google Scholar
• Troussard X., Gindrey B., Batho A., Macro M., Peny A.M., Reman O., Berger E., Leporrier M. Double hemibody irradiation with GM-CSF support in multiple myeloma. A pilot study. Blood 1992; 80(Suppl. 1)1474–1474, 121a.
   Google Scholar
• Vadhan-Raj S., Jeha S., Broxmeyer H.E., Hittelman W.N., Thompson P., Arcenas A., Hoots W.K., Estey E., Garrison L. Stimulation of haematopoiesis by Pixy 321 (GM-CSF/IL-3 fusion protein) in patients with bone marrow failure. Blood 1993; 82(10)1449–1449, 366a.
   Web of Science ®Google Scholar
• Valverde N.J., Cordeiro J.M., Oliveira A.R., Brandao-Mello C.E. The acute radiation syndrome in the 137Cs Brazilian accident, 1987. The Medical Basis for Radiation Accident Preparedness, II, Clinical Experience and Follow-up Since 1979, R.C. Ricks, S.A. Fry. Elsevier, North Holland. 1990; 89–107, In
   Google Scholar
• Welte K., Zeidler C., Reiter A., Muller W., Odenwald E., Souza L., Riehm H. Differential effects of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor in children with severe congenital neutropenia. Blood 1990; 75: 1056–1063
   PubMed Web of Science ®Google Scholar
• Williams D.A. Ex vivo expansion of haematopoietic stem and progenitor cells—robbing Peter to pay Paul?. Blood 1993; 81: 3169–3172
   PubMed Web of Science ®Google Scholar
• Wilson A. Meeting report (with extended abstracts). CEIR Forum on the effects of cytokines on radiation responses. International Journal of Radiation Biology 1993; 63: 529–540
   PubMed Web of Science ®Google Scholar
• Zimmer B.M., Berdel W.E., Ludwig W.D., Notter M., Reufi B., Thiel E. Fatal spleen rupture during induction chemotherapy with GM-CSF priming for acute monocytic leukemia. Clinical case report and in vitro studies. Leukemia Research 1993; 17: 277–283
   PubMed Web of Science ®Google Scholar
• Zsebo K.M., Smith K.A., Hartley C.A., Greenblatt M., Cooke K., Rich W., McNiece I.K. Radioprotection of mice by recombinant rat stem cell factor. Proceedings of the National Academy of Sciences, USA 1992; 89: 9464–9468
   PubMed Web of Science ®Google Scholar