15
Views
23
CrossRef citations to date
0
Altmetric
Research Article

P53 deficiency produces fewer regenerating spermatogenic tubules after irradiation

Pages 677-682 | Published online: 03 Jul 2009

References

  • BIANCHI, M., 1983, Cytotoxic insult to germinal tissue: Part. 1, Testis. In Cytotoxic Insult to Tissue, edited by C. S. Potten and J. H. Hendry (Edinburgh: Churchill-Livingstone), pp. 258–307.
  • BIANCHI, M., DELIC, J. I., HURTADO-DE-CATALFO, G. and HENDRY, J. H., 1985, Strain differences in the radiosensitivity of mouse spermatogonia. InternationalJournal of Radiation Biology, 48, 579–588.
  • BRASH, D. E., 1996, Cellular proofreading. Nature Medicine, 2, 525–527.
  • CLARKE, A. R., PURDIE, C. A., HARRISON, D. J., MORRIS, R. G., BIRD, C. C., HOPPER, M. L. and WYLLIE, A. H., 1993, Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature, 362, 849–852.
  • Cu' Y, WANG, L., LORD B. I., ROBERTS S. A., POTTEN C. S., HENDRYI H. and SCOTT D., 1996, Gamma-ray induced cell killing and chromosome abnormalities in p53-deficient mice. Radiation Research (in press).
  • DI LEONARDI, A., LINKE, S. P., CLARKIN, K. and WAD, G. M., 1994, DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cipl in normal human fibroblasts. Genes and Development, 81, 2540–2551.
  • DONEHOWER, L. A., HARVEY, M., SLAGLE, B. L., MCARTHUR, M. J., MONTGOMERY J R. C. A., BUTEL, J. S. and BRADLEY, A., 1992, Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature, 356, 215–221.
  • HENDRY, J. H., 1979, A new derivation from split-dose data of the complete survival curve for clonogenic normal cells in vivo. Radiation Research, 78, 404–414.
  • HENDRY, J. H., ROBERTS, S. A. and POTTEN, C. S., 1992, The clonogen content of murine intestinal crypts: depen-dence on radiation dose used in its determination. Radiation Research, 132, 115–119.
  • LEE, J. M. and BERNSTEIN, A., 1993, P53 mutations increase resistance to ionising radiation. Proceedings of the National Academy Sciences, USA, 90, 5742–5746.
  • LOWE, S. W., SCHMITT, E. M., SMITH, S. W., OSBORNE, B. A. and JACKS, T., 1993, P53 is required for radiation-induced apoptosis in mouse thymocytes. Nature, 362, 847–849.
  • LoTEm, J. and SACHS, L., 1993, Hematopoietic cells from mice deficient in wild-type p53 are more resistant to induction of apoptosis by some agents. Blood, 82, 1092–1096.
  • MERRITT, A. J., POTTEN, C. S., KEMP, C., HICKMAN, J., LANE, A., BALMAIN, A. and HALL, P., 1994, The role of p53 in spontaneous and radiation-induced intestinal cell apoptosis in normal and p53 deficient mice. Cancer Research, 54, 614–617.
  • O'CONNOR, P. M., JACKMAN,J., JONDLE, D., BHATIA, K., MAGRATH, I. and KOHN, K. W., 1993, Role of the p53 tumor suppres-sor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma cell lines. Cancer Research, 53, 4776–4780.
  • PARDO, F. S., Su, M., BORER, C., PREFFER, F., DOMBROWSKI, D., GERWECK, L. and SCHMIDT, E. V., 1994, Transfection of rat embryo cells with mutant p53 increases their intrinsic radiation resistance. Radiation Research, 140, 180–185.
  • POTTEN, C. S., HENDRY, J. H., MooRE, J. V., 1987, New estimates of the number of cryptogenic cells in crypts of murine small intestine. Virchows Archives B, 53, 227–234.
  • ROBERTS, S. A., 1990, DRFIT: a program for fitting radiation survival models. International Journal of Radiation Biology, 57, 1243–1246.
  • ROBERTS, S. A., HENDRY, J. H. and POTTEN C. S., 1995, Deduction of the clonogen content of intestinal crypts: a direct comparison of two-dose and multiple-dose methodologies. Radiation Research, 141, 303–308.
  • ROTTER, V., SCHWARTZ, D., ALMON, E., GOLDFINGER, N., KAPON, A., MESHORER, A., DONEHOWER, L. A. and LEVINE, A. J., 1993, Mice with reduced levels of p53 protein exhibit the testicular giant-cell degenerative syndrome. Proceedings of the National Academy of Sciences, USA, 90, 9075–9079.
  • SCHWARTZ, D., GOLDFINGER, N. and ROTTER, V., 1993, Expression LOWE, of p53 protein in spermatogenesis is confined to the tetraploid pachytene primary spermatocytes. Oncogene, 8, 1487–1494.
  • SJoBLom, T. and LAHDETIEJ., 1996, Expression of p53 in normal and y-irradiated rat testis suggests a role for p53 in meiotic recombination and repair. Oncogene, 12, 2499–2505.
  • SLICKENMEYER, W. J., NELSON, W. G., SLEBOS, R. J. and RASTAN, M. B., 1993, Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage. Cancer Research, 53, 4164–4167.
  • VAN BEEK, M. E. A. B., DAvms, J. A. G. and DE Roou, D. G., 1986,
  • Variation in the sensitivity of the mouse spermatogo-nial stem cell population to fission neutron irradiation during the cycle of the seminiferous epithelium. Radia-tion Research, 108, 282–295.
  • WITHERS, H. R., 1985, Spermatogenic colonies. In Cell Clones; Manual of Mammalian Cell Techniques, edited by C. S. Potten and J. H. Hendry (Edinburgh: Churchill-Living-stone), pp. 105–113.
  • WITHERS, H. R., HUNTER, N., BARKLEY, H. T. and REID, B.O., 1974, Radiation survival and regeneration characteristics of spermatogenic stem cells of mouse testis. Radiation Research, 57, 88–103.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.