Uptake and retention of nitroimidazole-carboranes designed for boron neutron capture therapy in experimental murine tumours: 11 detection by B magnetic resonance spectroscopy

References

• ADAMS, G. E., AHMED, I., SHELDON, P. W. and STRATFORD, I. J., 1984, Radiation sensitisation and chemopotentiation: R5U1069 a compound more efficient than misonida-zole in vitro and in vivo. British Journal of Cancer, 49, 571–578.
   PubMed Web of Science ®Google Scholar
• BARTH, R. F., SOLO WAY, A. H. and FAIRCHILD, R. G., 1990, Boron neutron capture therapy of cancer. Cancer Research, 50, 1061–1070.
   PubMed Web of Science ®Google Scholar
• BARTH, R. F., SOLOWAY, A. H., FAIRCHILD, R. G. and BRUGGER, R. M., 1992, Boron neutron capture therapy for cancer. Realities and prospects. Cancer, 70, 2995–3007.
   PubMed Web of Science ®Google Scholar
• BENDEL, p., DAVIS, M., BERMAN, E. and KABALKA, G. W., 1990, A method for imaging nuclei with a short T2 relaxation and its application to boron-11 imaging of a BNCT agent in an intact rat. Journal of Magnetic Resonance, 88, 369–375.
   Web of Science ®Google Scholar
• CODERRE, J., RUBIN, p., FREEDMAN, A., HANSEN, J., WOODING, T. S., JOEL, D. and GASH, D., 1994, Selective ablation of rat tumours by boron neutron capture therapy. Interna-tional Journal of Radiation Oncology, Biology and Physics, 28, 1067–1077.
   PubMed Web of Science ®Google Scholar
• GARRECHT, B. M. and CHAPMAN, J. D., 1983, The labelling of EMT-6 tumours in BALB/C mice with 14C-misonidazole. British Journal of Radiology, 56, 745–753.
   PubMedGoogle Scholar
• GOUDGAON, N. M., ELKATTAN, G. F. and SCHINAZI, R. F., 1994, Boron containing pyrimidines, nucleosides and oligonucleotides for neutron capture therapy. Nucleo-sides and Nucleotides, 13, 849–880.
   Web of Science ®Google Scholar
• HATANAKA, H. and NAKAGAWA, Y, 1994, Clinical results of long-surviving brain tumour patients who underwent boron neutron capture therapy. International Journal of Radia-tion Oncology, Biology, and Physics, 28, 1061–1066.
   PubMed Web of Science ®Google Scholar
• HAWTHORNE, M. F., 1993, The role of chemistry in the devel-opment of boron neutron capture therapy of cancer. Angewandte Chemie, International Edition in English, 32, 950–984.
   Web of Science ®Google Scholar
• HOECKEL, M., SCHLENGER, K., KNOOP, C. and VAUPEL, p., 1991, Oxygenation of carcinomas of the uterine cervix: evaluation by computerised 02 tension measure-ments. Cancer Research, 51, 6098–6102.
   PubMed Web of Science ®Google Scholar
• KABALKA, G. W., DAVIS, M. and BENDEL, P., 1988, Boron-11 MRI and MRS of intact animals infused with a boron neutron capture agent. Magnetic Resonance in Medicine, 8, 231–237.
   PubMed Web of Science ®Google Scholar
• KABALKA, G. W., CHENG, G-Q., BENDEL, p., MICCA, P. L. and SLATKIN, D. N., 1991, In vivo boron-11 MRI and MRS using (B24H22S2)4- in the rat. Magnetic Resonance Imaging, 9, 969–973.
   Google Scholar
• KENNEDY, K. A., TEICHER, B. A., ROCKWELL, S. and SARTORELLI, A. C., 1980, The hypoxic tumour cell: a target for selective cancer chemotherapy. Biochemical Pharmacology, 29, 1–8.
   PubMed Web of Science ®Google Scholar
• KEYES, S. R., FRACASSO, P. M., HEIMBROOK, D. C., ROCKWELL, S., SUGAR, S. G. and SARTORELLI, A. C., 1985, Chemother-apeutic attack of hypoxic cells by the bioreductive agent, mitomycin C. Cancer Research, 45, 3642–3645.
   PubMedGoogle Scholar
• MIURA, M., GABEL, D., OENBRINK, G. and FAIRCHILD, R. G., 1992, Preparation of carboranyl porphyrins for boron neu-tron capture therapy. Tetrahedron Letters, 33, 2247–2250.
   Google Scholar
• OKUNIEFF, P., HOECKEL, M., DUNPHY, E. P., SCHLENGER, K., KNOOP, C. and VAUPEL, P., 1993, Oxygen tension dis-tributions are sufficient to explain the local response of human breast tumours treated with radiation alone. International Journal of Radiation Oncology Biology and Physics, 26, 631–636.
   PubMed Web of Science ®Google Scholar
• SCOBIE, M. and THREADGILL, M. D., 1994a, Tumour-targetted boranes. Part 3. Synthesis of carbamate-linked nitroimidazole-carboranes designed for boron neu-tron capture therapy of cancer. Journal of the Chemical Society, Perkin Transactions, 1, 2059–2063.
   Google Scholar
• SCOBIE, M. and THREADGILL, M. D., 1994b, Tumour-targetted boranes. 4. Synthesis of nitroimidazole-carboranes with polyether-isoxazole links. Journal of Organic Chem-istry, 59, 7008–7013.
   Web of Science ®Google Scholar
• STRATFORD, I. J., 1992, Bioreductive drugs in cancer therapy. British Journal of Radiology, (Suppl. 24), 128–136.
   Google Scholar
• STRATFORD, I. J., ADAMS, G. E., BREMNER, J. C. M., COLE, S., EDWARDS, H. E., ROBERTSON, N. and WOOD, P. J., 1994, Manipulation and exploitation of the tumour micro-environment for therapeutic benefit. International Journal of Radiaion Biology, 65, 85–94.
   Google Scholar
• SWENSON, D. H., LASTER, B. H. and METZGER, R. L., 1996, Synthesis and evaluation of a boronated nitroimida-zole for boron neutron capture therapy. Journal of Medicinal Chemistry, 39, 1540–1544.
   PubMed Web of Science ®Google Scholar
• TJARKS, W., ANISUZZAMAN, A. K. M., Liu, L., SOLOWAY, R. F., BARTH, R. F., PERKINS, D. J. and ADAMS, D. M., 1992, Synthesis and in vitro evaluation of boronated uridine and glucose derivatives for boron neutron capture therapy. Journal of Medicinal Chemistry, 35, 1628–1633.
   Google Scholar
• TWENTYMAN, P. R., BROWN, J. M., GRAY, J. W., FRANKO, A. L., SCA/LES, M. A. and KALLMAN, R. F., 1980, A new mouse tumour model system (RIF-1) for comparison of end-point studies. Journal of the National Cancer Institute, 64, 595–604.
   Google Scholar
• WILBUR, D. S., HAMLIN, D. K., LIVESY, J. C., SRIVASTAVA, R. R., LARAMORE, G. E. and GRIFFIN, T. W., 1994, Synthesis and radioiodination of a nic/o-1,2-carboranyl derivative of 2-nitro imidazole. Nuclear Medicine and Biology, 21, 601 — 611.
   Web of Science ®Google Scholar
• WOOD, P. J. SANSOM, J. M., STRATFORD, L J., SZABO, C., COLE, S., BUTLER, S., THIEMERMANN, C. and ADAMS, G. E., 1994, Induction of hypoxia in experimental murine tumours by the nitric oxide synthase inhibitor, NG-nitro-L-arginine. Cancer Research, 54, 6458–6463.
   PubMed Web of Science ®Google Scholar
• WYZLIC, I. M. and SoLowfio A. H., 1992, A general, convenient way to carborane-containing amino acids for boron neutron capture therapy. Tetrahedron Letters, 33, 7489–7490.
   Google Scholar
• WYZLIC, I. M., TJARKS, W., SOLOWAY, A. H., ANISUZZAMAN, A. K. M., RONG, F. G. and BARTH, R. F. (1994). Strategies for the design and synthesis of boronated nucleic acid and protein components as potential delivery agents for neutron capture therapy. International Journal of Radia-tion Oncology, Biology and Physics, 28, 1203–1214.
   Google Scholar