18
Views
45
CrossRef citations to date
0
Altmetric
Research Article

Chromosome analysis by fluorescence in situ hybridization: further indications for a non-DNA-proportional involvement of single chromosomes in radiation-induced structural aberrations

Pages 385-392 | Published online: 03 Jul 2009

  • BARRIOS, L., M IROÂ, R., CABALLIÂN, M. R., FUSTER, C., G UEDEA, F., SUBIAS, A., and EGOZCU E, J., 1989, Cytogenetic effects of radiotherapy; breakpoint distribution in induced chromosome aberrations. Cancer Genetics and Cytogenetics, 41, 61 -70.
  • BAUCH INGER, M., and GOÈTZ, G., 1979, Distribution of radiation induced lesions in human chromosomes and dose-effect relation analysed with G-banding. Radiation and Environmental Biophysics, 16, 355 -366.
  • BAUCH INGER, M., SCH MID, E., ZITZELSBERGER, H., BRASELMANN, H., and NAHRSTEDT, U., 1993, Radiation-induced chromosome aberrations analysed by two-colour ¯ uorescence in situ hybridization with composite whole chromosome-specific DNA probes and a pancentromeric DNA probe. International Journal of Radiation Biology, 64, 179-184.
  • CO LLINS, C., KUO, W. L., SEGRAVES, R., FUSCO E, J., PINKEL, D., and GRAY, J. W., 1991, Construction and characterization of plasmid libraries enriched in sequences from single human chromosomes. Genomics, 11, 997 -1006.
  • FINNON, P., LLOYD, D. C., and EDWARDS, A. A., 1995, Fluorescence in situ hybridization detection of chromosomal aberrations in human lymphocytes: applicability to biological dosimetry. International Journal of Radiation Biology, 68, 429 -435.
  • JOH NSO N, G. D., and DE C. N OG UEIRA A RAUJO, G. M., 1981, A simple method of reducing the fading of immuno-¯ uorescenceduringmicroscopy.Immunological Methods, 43, 349 -350.
  • KNEHR,S.,ZITZELSBERGER,H., BRASELMANN,H., and
  • BAUCH INGER, M., 1994, Analysis for DNA-proportional
  • distribution of radiation-induced chromosome aberra
  • tions in various triple combinations of hum an chromo
  • somesusing¯ uorescenceinsituhybridization.
  • International Journal of Radiation Biology, 65, 683 -690.
  • LUCAS, J. N., AWA, A., STRAUME, T., PO GGENSEE, M., KODAMA, Y., N AKANO, M., O HTAKI, K., WEIER, H. -U., PINKEL, D., GRAY, J., and LITTLEFIELD, G., 1992, Rapid translocation frequency analysis in man decades after exposure to ionizing radiation. International Journal of Radiation Biology, 62, 53 -63.
  • M ORTON, N. E., 1991, Parameters of the human genome. Proceedings of the National Academy of Sciences, USA, 88, 7474-7476.
  • SACHS, R. K., AWA, A., KO DAMA, Y., N AKANO, M., O HTAKI, K., and LUCAS, J. N., 1993, Ratios of radiation-produced chromosome aberrations as indicators or large-scale DNA-geometry during interphase. Radiation Research, 133, 345 -350.
  • SAVAGE, J. R. K., and SIMPSON, P., 1994, FISH `painting‚ patterns resulting from complex exchanges. Mutation Research, 312, 51 -60.
  • SCH MID, E., ZITZELSBERGER, H., BRASELMANN, H., GRAY, J. W., and BAUCH INGER, M., 1992, Radiation-induced chromosome aberrations analysed by ¯ uorescence in situ hybridization with a triple combination of composite whole chromosome-specifi c DNA probes. International Journal of Radiation Biology, 62, 673-678.
  • TUCKER, J. D., and SENFT, J. R., 1994, Analysis of naturally occurring and radiation-induced breakpoint locations in human chrom osomes 1, 2 and 4. Radiation Research, 140, 31 -36.
  • TUCKER, J. D., MO RGAN, W. F., AWA, A. A., BAUCH INGER, M., BLAKEY, D., CORNFORTH, M. N., LITTLEFIELD, L. G., NATARAJAN, A. T., and SHASSERE, C., 1995, A proposed system for scoring structural aberrations detected by chromosome painting. Cytogenetics and Cell Genetics, 68, 211-221.
  • W EIER, H.-U. G., LUCAS, J. N., POGG ENSEE, M., SEGRAVES, R., PINKEL, D., and GRAY, J. W., 1991, Two-color hybridization with high complexity chromosome-specific probes and a degenerate alpha-satellite probe DNA allows unambiguousdiscriminationbetweensymmetrical and asymm etrical translocations. Chromosoma, 100, 371-376.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.