Radiosensitivity of human breast cancer cell lines of different hormonal responsiveness. Modulatory effects of oestradiol

References

• BARTEK, J., IGG0, R., GANNON, J., and LANE, D. P., 1990, Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines. Oncogene, 10, 893–899.
   Google Scholar
• BoDR, V. A., PHILLIPS, D. H., and HANAWALT, P. C., 1987, Heterogeneous DNA damage and repair in the mam-malian genoma. Cancer Research, 47, 6426–6436.
   PubMedGoogle Scholar
• CHM, S. M., OLEINICK, N. L., FRIEDMAN, L. R., and STAMBROOK, J. P., 1982, Hypersensitivity of DNA in transcriptionally active chromatin to ionizing radiation. Biochimica et Biophysica Acta, 699, 15–21.
   PubMedGoogle Scholar
• DEL MORAL, R., FERNANDEZ, J. 0., LOPEZ-GONZALEZ, J. D., GOMEZ, M., RUIZ DE ALMODOVAR, J. M., OLEA, N., and PEDRAZA, V., 1991, Kinetics of cellular proliferation and hormonal receptors in EVSA-T breast cancer cell line. Revista Espanola de Fisiologia, 7, 25–30.
   Google Scholar
• ELIA, M. C., and BRADLEY, M. 0., 1992, Influence of chromatin structure on the induction of DNA double strand breaks by ionizing radiation, Cancer Research, 52, 1580–1586.
   Google Scholar
• HAIMOVITZ-FRIEDMAN, A., VLODAVSKY, I., CHAUDHURI, A., WITTE, L., and FUKS, Z., 1991, Autocrine effects of fibroblast growth factor in repair of radiation damage in endothelial cells. Cancer Research, 51, 2552–2558.
   PubMed Web of Science ®Google Scholar
• ILIAKIS, G. E., METZGER, L., DENKO, N., and STAMATO, T. D., 1991, Detection of DNA double-strand breaks in synchro-nous cultures of CHO cells by means of asymmetric field inversion gel electrophoresis. International Journal of Radiation Biology, 59, 321–341.
   PubMed Web of Science ®Google Scholar
• KEYDAR, I., CHEN, L., KARBY, S., WEISS, F. R., DELAREA, J., RADU, M., CHAITCIK, S. and BRENNER, H. J., 1979, Establishment and characterization of a cell line of human breast carcinoma origin. European Journal of Cancer, 15, 659–670.
   PubMed Web of Science ®Google Scholar
• KWOK, T. T., and SUTHERLAND, R. M., 1989, Enhancement of sensitivity of human squamous carcinoma cells to radiation by epidermal growth factor. Journal of the National Cancer Institute, 81, 1020–1024.
   PubMed Web of Science ®Google Scholar
• LIPPMAN, M., BOLAN, G., and HUFF, K., 1976, The effects of estrogen and antiestrogens on hormone-responsive human breast cancer in long-term tissue culture. Cancer Research, 36, 4595–4601.
   PubMed Web of Science ®Google Scholar
• LOTTERING, M. L., HAAG, M., and SEEGERS, J., 1992, Effects of 17/3-estradiol metabolites on cell cycle events in MCF-7 cells. Cancer Research, 52, 5926–5932.
   PubMed Web of Science ®Google Scholar
• MCILWRATH, A. J., VASEY, P. A., Ross, G. M., and BROWN, R., 1994, Cell cycle arrests and radiosensitivity of human tumor cell lines: Dependence on wild-type p53 for radio-sensitivity. Cancer Research, 54, 3718–3722.
   PubMed Web of Science ®Google Scholar
• NUNEZ, M. I., VILLALOBOS, M., OLEA, N., VALENZUELA, M. T., PEDRAZA, V., MCMILLAN, T. J., and RUIZ DE ALMODOVAR, J. M., 1995, Radiation-induced DNA double-strand break rejoining in human tumour cells. British Journal of Cancer, 71, 311–316.
   Google Scholar
• OKAYASU, R., BLöVHER, D. M., and Rums, G. E., 1988, Variation through the cell cycle of DNA neutral filter elution dose response in X-irradiated synchronous CHO-cells. International Journal of Radiation Biology, 53, 729–747.
   Google Scholar
• OLEA, N., VILLALOBOS, M., RUIZ DE ALMODOVAR, J. M., and PEDRAZA, V., 1992, MCF-7 Breast cancer cells grown as multicellular spheroids in vitro: effects of 17)3 estradiol. International Journal of Cancer, 50, 112–117.
   PubMed Web of Science ®Google Scholar
• OLEA, N., VILLALOBOS, M., THOMAS, J., LOPEZ GONZALEZ, J. D., RUIZ DE ALMODOVAR, J. M., and PEDRAZA, V., 1987, Gine-tica de proliferación en cultivos celulares MCF-7. II. Sincronización y reclutamiento celular hormonal-mente-inducidos. Revista Espanola de Fisiologia, 43, 215–222.
   PubMedGoogle Scholar
• OLIVE, P. L., 1992, DNA organization affects radiosensitivity and detection of initial DNA strand breaks. Interna-tional Journal of Radiation Biology, 62, 389–396.
   PubMed Web of Science ®Google Scholar
• OLIVE, P. L., WLODEKD, C., and BANATH, J. P., 1991, DNA double strand breaks measured in individual cells subjected to gel electrophoresis. Cancer Research, 51, 4671–4676.
   PubMed Web of Science ®Google Scholar
• OSBORNE, C. K., BOLDT, D., and ESTRADA, P., 1984, Human breast cancer cell cycle synchronization by estrogens and anti-estrogens in culture. Cancer Research, 43, 1433–1439.
   Google Scholar
• PEACOCK, J. H., EADY, J. J., EDWARDS, S. M., MCMILLAN, T. J., and STEEL, G. G., 1992, The intrinsic affi ratio for tumour cells: is it a constant? International Journal of Radiation Biology, 61, 479–487.
   PubMed Web of Science ®Google Scholar
• PEACOCK, J. H., RUIZ DE ALMODOVAR, J. M., MCMILLAN, T. J., and STEEL, G. G., 1993, The nature of the initial slope of radiation cell survival curves. British Journal of Radiology, Suppl. 24, 57–60.
   Google Scholar
• ROBINSON, J. P., 1993, Measurements of DNA. In: Handbook of Flow Cytometry Methods. Edited by: J. P. Robinson, Z. Darzynkiewicz, P. Dean, L. Dressler, H. Tanke and L. Wheeles (Wiley-Liss, New York), pp. 90–126.
   Google Scholar
• RUIZ DE ALMODOVAR, J. M., BUSH, C., PEACOCK, J. H., STEEL, G. G., WHITAKER, S. J., and MCMILLAN, T. J., 1994a, Dose-Rate effect for DNA damage induced by ionizing radiation in human tumor cells. Radiation Research, 138, S93—S96.
   Google Scholar
• RUIZ DE ALMODOVAR, J. M., MCMILLAN, T. J., OLEA, N., PEACOCK, J. H., PEDRAZA, V., STEEL, G. G., VILLALOBOS, M., and WHITAKER, S. J., 1993, Aspectos moleculares, celulares y multicelulares de la radiosensibilidad, In: Avances de la Investigacion Oncologica Espanola. Edited by: J. C. Lacal and M. Barbacid. (Farmiindustria, serie ciendfica, Madrid), pp. 187–226.
   Google Scholar
• Ruiz DE ALMODóVAR, J. M., NUNEZ, M. I., MCMILLAN, T. J., OLEA, N., MORT, N., VILLALOBOS, M., PEDRAZA, V., and STEEL, G. G., 1994c, Initial radiation-induced DNA damage in human tumour cell lines: a correlation with intrinsic cellular radiosensitivity, British Journal of Cancer, 69, 457–462.
   Google Scholar
• RUIZ DE ALMOD6VAR, J. M., STEEL, G. G., WHITAKER, S. J., and MCMILLAN, T. J., 1994b, A comparison of methods for calculating DNA double-strand break induction fre-quency in mammalian cells by pulsed-gel electro-phoresis. International Journal of Radiation Biology, 65, 641–649.
   Google Scholar
• SARKARIA, J. N., GIBSON, D. F. C., JORDAN, V. C., FOWLER, J. F., LIDSTRIM, M. J., and MULCAHY, R. T., 1993, Tamoxifen-induced increase in the potential doubling time (Tpot) of MCF-7 xenografts as determined by bromodeoxyuridine labelling and flow cytometry. Cancer Research, 53, 4413–4417.
   PubMedGoogle Scholar
• SARKARIA, J. N., MILLER, E. M., PARKER, C. J., JORDAN, V. C., and MULCAHY, R. T., 1994, 4-Hydroxytamoxifen, an active metabolite of tamoxifen, does not alter the radiation sensitivity of MCF-7 breast carcinoma cells irradiated in vitro. Breast Cancer Research and Treatment, 30, 159–165.
   PubMedGoogle Scholar
• SILES, E., VILLALOBOS, M., VALENZUELA, M. T., NUNEZ, M. I., GORDON, A., MCMILLAN, T. J., PEDRAZA, V., and RUIZ DE ALMODOVAR, J. M., 1996, Relationship between p53 status and radiosensitivity in human tumour cell lines, 73, 581–588.
   Google Scholar
• SOTO, A. M., and SONNENSCHEIN, C., 1985, The role of estrogens on the proliferation of human breast tumor cells (MCF-7). Journal of Steroid Biochemistry, 23, 87–94.
   PubMedGoogle Scholar
• SOULE, H. D., VAZQUEZ, J., LONG, A., ALBERT, S., and BRENNAN, M. J., 1973. A human cell line from a pleural effusion derived from a breast carcinoma. Journal of the National Cancer Institute, 51, 1409–1413.
   PubMed Web of Science ®Google Scholar
• SWEIGERT, A., ROWLEY, A., WARTERS, R., and DETHLEFSEN, L., 1988, Cell cycle effect on the induction of DNA double strand breaks by X-ray. Radiation Research, 121, 196–205.
   Google Scholar
• TAKAHASHI, K., and SUZUKI, K., 1993, Association of insulin-like growth-factor-I-induced DNA synthesis with phosphor-ylation and nuclear exclusion of p53 in human breast cancer MCF-7 cells. International Journal of Cancer, 55, 453–458.
   PubMedGoogle Scholar
• VAN DER MEER, Y, HUISKAMP, R., DAVIDS, J. A. G., VAN DER TWEEL, I., and DE Roou, D. G., 1992, The sensitivity of quiescent and proliferating mouse spermatogonial stem cells to X irradiation. Radiation Research, 130, 289–295.
   Google Scholar
• VILLALOBOS, M., ARANDA, M., NUN' EZ, M. I., BECERRA, D., OLEA, N., RUIZ DE ALMOD6VAR, J. M., and PEDRAZA, V., 1995a, Interaction between ionizing radiation, estrogens and antiestrogens in the modification of tumor micro-environment in estrogen dependent multicellular spheroids. Acta Oncologica, 34, 413–417.
   Google Scholar
• VILLALOBOS, M., OLEA, N., BROTONS, J. A., OLEA-SERRANO, M. F., Ruiz DE ALMODENAR, J. M., and PEDRAZA, V., 1995b, The E-SCREEN assay: Comparison between different MCF7 cell stocks. Environ Health Perspectives, 103, 844–850.
   Google Scholar
• VILLALOBOS, M., OLEA, N., GORGOJO, L., LOPEZ-GONZALEZ, J. G., RUIZ DE ALMODóVAR, J. M., and PEDRAZA, V., 1987, Gine-tica de proliferación en cultivos celulares MCF-7. I. Influencia relativa de los estrogenos y antiestrOgenos sobre el crecimiento de la población celular. Revista Espanola de Fisiologia, 43, 209–214.
   Google Scholar
• WARD, J. F., 1990, The yield of DNA double strand breaks produced intracellularly by ionizing radiation: a review, 1990. International Journal of Radiation Biology, 44, 75–85.
   Google Scholar
• WAZER, D. E., JOYCE, M., CHAN, W., GEWITZ, D., PECK-SUN, L., SOLARE, G., and SCHMIDT-ULRICH, R. K., 1993, Effects of Tam oxifen on the radiosensitivity of hormonally responsive and unresponsive breast carcinoma cells. Radiation Oncology Investigations, 1, 20–28.
   Google Scholar
• WAZER, D. E., TERCILLA, 0. F., LIN, P. S., and SCHMIDT-ULRICH, R. K., 1989, Modulation in the radiosensitivity of MCF-7 human breast carcinoma cells by 1713 estra-diol and tamoxifen. British Journal of Radiology, 62, 1009–1013.
   Google Scholar
• WHEELER, K. T., NELSON, G. B., TERRELL, K. E., and WALLEN, C. A., 1988, Regulation of DNA repair kinetics in prolif-erative and quiescent tumor cells. International Journal of Radiation Biology, 54, 245–255.
   PubMed Web of Science ®Google Scholar
• WHITAKER, S. J., UNG, Y, and MCMILLAN, T. J., 1995, DNA double strand break induction and rejoining as determinant of human tumor cell radiosensitivity. A pulsed gel electrophoresis study. International Journal of Radiation Biology, 67, 7–18.
   PubMed Web of Science ®Google Scholar