- GLACKEN, M. W., 1988, Catabolic control of mammalian cell Culture. Biotechnology, 6, 1041-1050.
- HAMILTON, E., FENELL, M. and STAFFORD, D. M., 1995, Modification of tumor glucose metabolism for therapeutic benefit. Acta Oncologica, 34, 429-433.
- HOLAHAN, P. K., KNIZNER, S. A., GABRIEL, C. M. and SWENBBRG C. E., 1988, Alterations in phosphate metabolism during cellular recovery of radiation damage in yeast, international Journal of Radiation Biology, 54, 545-562.
- HOPPER, S. and SEGAL, H. L., 1962, Kinetic studies of rat liver ghitamic-alanine transaminase. Journal of Biological Chemistry, 237, 3189-3195.
- HORNSBY, P. J. and GILL, G. N., 1981, Regulation of glutamine and pyruvate oxidation in cultured adrenocortical cells by Cortisol, antioxidants and oxygen: effects on cell proliferation. Journal of Cellular Physiology, 109, 111-120.
- JACOBS, A. E. M., OOSTERH OF, A. and VEERKAMP, J. H., 1990, 2-Deoxy-D-glucose uptake in cultured human muscle cells, Biochimica et Blophyslca Acta, 1051, 230-236.
- JAIN, V. K., GUPTA, I. and LATA, K., 1982, Energetics of cellular repair processes in a respiratory-deficient mutant of yeast. Radiation Research, 92, 463-473.
- JAIN, V. K., HOLTZ, G. W., POHLIT, W. and PUROHIT, S. C., 1977a, Inhibition of unscheduled DNA synthesis and repair of potentially lethal X-ray damage by 2-deoxy-D-glucose in yeast. International Journal of Radiation Biology, 32, 175-180.
- JAIN, V. K., KALIA, V. K., SHARMA, R., MAHARAIAN, V. and MENON, M., 1985, Effects of 2-deoxy-D-glucose on gtycolysis, proliferation kinetics and radiation response of human Cancer Cells. International Journal of Radiation Oncology, Biology, Physics, 11, 943-950.
- JAIN, V. K., POHLIT W. and PUROHIT S. C., 1975, Influence of energy metabolism on the repair of X-ray damage in living cells IV. Effects of 2-deoxy-D-glucose on the repair phenomena during fractionated irradiation of yeast. Radiation and Environmental Biophysics, 12, 315-320.
- JAIN, V. K., PORSCHEN, W. and FEINENDEGEN, L. E., 1977b, Optimization of cancer therapy: Part II-Effects of combining 2-deoxy-D-glucose treatment with gammairradiation On Sarcoma-180. Indian Journal of Experimental Biology, 15, 714-718.
- JAIN, V. K., PUROHIT, S. C. and POHLIT, W., 1977c, Optimization of cancer therapy: Part I--X-ray induced potentially lethal damage by 2-deoxy-D-glucose in Ehrlich ascites tumour Cells. Indian Journal of Experimental Biology, 15, 711-713.
- KAPISZEWSKA, M. and LANGE, C., 1988, The effects of reduced temperature and/or starvation conditions on the radiosensitivity and repair of potentially lethal damage and sublethal damage in L5178Y-R and L5178Y-S cells. Radiation Research, 113, 458-472.
- LITTLE, J. B., 1971, Repair of potentially lethal radiation damage in mammalian cells: enhancement by conditioned medium from stationary cultures, international Journal of Radiation Biology, 20, 87-92.
- MATSUDAIRA, H., FURUNO, I. and OTSUKA, H., 1970, Possible requirement of adenosine triphosphate for the rejoining of x-ray induced damage breaks in the DNA of Ehrlich ascites tumour Cells. International Journal of Radiation Biology, 17, 339-347.
- MCKEEHAN, W. L., 1982, Glycolysis, glutaminolysis and cell proliferation. Cell Biology International Reports, 6, 1041-1050.
- MEDINA, M. A., SANCHEZ-JIMENEZ, F., MARQUEZ, F. J., PEREZ-RODRIGUES, J., QUeSADA, A. R. and NUNEZ DE CASTRO, I., 1988, Glutamine and glucose as energy substrates for Ehrlich ascites tumour cells. Biochemistry International, 16, 339-347.
- PERSSON, M., BLEIBERG, B., Kiss, D. and MILES, J., 1991, Measurement of plasma acetate kinetics using high-performance liquid chromatography. Analytical Biochemistry, 198, 149-153.
- POHLIT, W. and HEYDER, I. R., 1981, The shape of dose-survival curves for mammalian cells and repair of potentially lethal damage analyzed by hypertonic treatment. Radiation Research, 87, 613-634.
- PUROHIT, S. C. and POHLIT, W., 1982, Experimental evaluation of the glucose antimetabolite, 2-deoxy-D-glucose (2-DG) as a possible adjuvant to radiotherapy of tumors: I. Kinetics of growth and survival of Ehrlich ascites tumor cells (EATC) in vitro and of growth of solid tumors after 2-DG and X-irradiation. International Journal of Radiation Oncology. Biology. Physics, 8, 495-499.
- REITZER, L. J., WICE, B. M. and KENNEL, D., 1979, Evidence that glutamine, not sugar, is the major energy source for Cultured HeLa Cells. Journal of Biological Chemistry, 8, 2669-2676.
- RICHTER, C., SCHWEIZER, M., COSSARIZZA, A. and FRANCESCHI, C., 1996, Control of apoptosis by the cellular ATP level. FEBS utters, 378, 107-110.
- SAUER, L. A., STAYMAN, J. W. and DAUCHY, R. T., 1982, Amino acid, glucose and lactic acid utilization in vivo by rat tumors. Cancer Research, 42, 4090-4097.
- SEYMOUR, C. B. and MOTHERSILL, C., 1987, The effect of glycolysis inhibitors on the recovery of CHO-K1 cells from split-dose irradiation. Acta Oncologica, 26, 367-371.
- SEYMOUR, C. B., MOTHERSILL, C. and MORIARTY, M. J., 1985, Glucose analogues alter the response of CHO-K1 cells to gamma irradiation. Acta Radiologica Oncology, 24, 351-356.
- SIMONIDES, W. S., ZAREMBA, R., VAN HARDEVELD, C. and VAN DER LAARSE, W. J., 1988, A nonenzymatic method for the determination of picomole amounts of lactate using HPLC: its application to single muscle fibres. Analytical Biochemistry, 169, 268-273.
- SPIRO, I. J., KENNEDY, K. A., STICKLER, R. and LING, C. C., 1985, Cellular and molecular repair of X-ray-induced damage: dependence on oxygen tension and nutritional Status. Radiation Research, 101, 144-155.
- THAMES, H. D., 1989, Repair kinetics in tissues: alternative models. Radiotherapy and Oncology, 14, 321-327.
- VAN STEVENINCK, J., 1968, Transport and transport-associated phosphorylation of 2-deoxy-D-glucose in yeast. Biochimica et Biophysica Acta, 163, 368-394.
- VARNES, M. E., TUTTLE, S. W. and BIAGLOW, J. E., 1984, Nitroheterocycle metabolism in mammalian cells. Stimulation of the hexose monophophosphate shunt. Biochemical Pharmacology, 33, 1671-1677.
- VERMA, A., SHARMA, R. and JAIN, V. K., 1982, Energetics of DNA repair in UV-irradiated peripheral blood leukocytes from chronic myeloid leukaemia patients. Photochemistry and Photobiology, 36, 627-632.
- WICK, A. N., DRURY, D. R., NAKADA, H. I. and WOLFE, J. B., 1957, Localization of the primary metabolic block produced by 2-dexyglucose. Journal of Biological Chemistry, 224, 963-969.
- YUSHOK, W. D., 1964, Metabolism of ascites tumor cells II. Inhibition of respiration by nonglycolyzable sugars phosphorylated by hexokinase. Cancer Research, 24, 187-192.
- ZIELKE, H. R., OZAND, P. T., TILDON, J. T., SEVDALIAN, D. A. and CORNBLATH, M., 1978, Reciprocal regulation of glucose and glutamine utilization by cultured human diploid fibroblasts. Journal of Cellular Physiology, 95, 41-48.
- ZIELKE, H. R., ZIELKE, C. I. and OZAND, P. T., 1984, Glutamine: a major energy source for cultured mammalian cells. Federation Proceedings, 43, 121-125.
The effects of 2-deoxyglucose and amino-oxyacetic acid on the radiation response of mammalian cells in vitro
Reprints and Corporate Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Academic Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.