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Research Article

RBE for the induction of apoptosis in human peripheral lymphocytes exposed in vitro to high-LET radiation generated by accelerated nitrogen ions

Pages 169-177 | Published online: 03 Jul 2009

  • CRAMP, W. A., YATVIN, M. B. and HARMS-RINGDAHL, M., 1994, Recent developments in the radiobiology of cellular membranes. AcIa Oncologica. 33, 945-952.
  • DATTA, R., COLE, A. and ROBINSON, S., 1976, Use of track-end alpha particles from 241Am to study radiosensitive sites in CHO Cells. Radiation Research, 65, 139-151.
  • DIGGS, L. W., STRUM, D. and BELL, A., 1985, The Morphology of Human Blood Cells. (Abbot Park, USA, Abbott Laboratories), p. 15.
  • GERACI, J. P., THROWER, P. D., JACKSON, K. L., CHRISTENSEN, G. M. and Fox, M. S., 1974, The RBE of cyclotron fast neutrons for interphase death in rat thymocytes in vitro. International Journal of Radiation Biology, 25, 403-405.
  • HAIMOVITZ-FRIEDMAN, A., KAN, C. C., EHLEITBR, D., PERSAUD, R. S., McLOUHLIN, M., FUKS, Z. and KOLESNICK, R. N., 1994, Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis. Journal of Experimental Medicine, 180, 525-535.
  • HEDGES, M. J. and HORNSEY, S., 1978, The effect of X-ray and neutrons on lymphocytes death and transformation. International Journal of Radiation Biology, 33, 291-300.
  • HEILMANN, J., RINK, H., TAUCHER-SCHOLZ, G. and KRAFT, G., 1993, DNA strand break induction and rejoining and cellular recovery in mammalian cells after heavy-ion irradiation. Radiation Research, 135, 46-55.
  • HENDRY, J. H., POTTEN, C. S., CHADWICK, C. and BIANCHI, M., 1982, Cell death (apoptosis) in the mouse small intestine after low doses: effects of dose-rate, 14.7 MeV neutrons, and 600 MeV (maximum energy) neutrons. International Journal of Radiation Biology, 42, 611-620.
  • HENDRY, J. H., POTTEN, C. S. and MERRITT, A., 1995, Apoptosis induced by high- and low-LET radiations. Radiation and Environmental Biophysics, 34, 59-62.
  • LANGLEY, R. E., PALAYOOR, S. T., COLEMAN, C. N. and BUMP, E. A., 1993, Modifiers of radiation-induced apoptosis. Radiation Research, 136, 320-326.
  • LOBRICH, M. COOPER, P. K. and RYDBERG, B., 1996, Non-random distribution of DNA double-strand breaks induced by particle irradiation. International Journal of Radiation Biology, 70, 493-503.
  • MEIJER, A. E., KRONQVIST, U.-S. E., LEWBNSOHN, R. and HARMS-RINGDAHL, M., 1997, The RBE of accelerated nitrogen-ions for apoptosis in human peripheral lymphocytes exposed in vitro. Proceedings of the 12th Meeting On Microdosimetry. In Microdosimetry--An Interdisciplinary Approach. Edited by D. T. Goodhead, P. O'Neill, H. G. Menzel (Hartnolls Ltd, Bodmin, Cornwall, UK) pp. 199-202.
  • MEIJER, A. E., KRONQVIST, U.-S. E., LEWENSOHN, R. and HARMS-RINGDAHL, M., 1997, Induction of apoptosis in human peripheral lymphocytes after in vitro exposure to high- or low-LET radiation. Proceedings of the 27th Annual Meeting of European Society of Radiation Biology. Radioprotection, 32, Numéro spécial de C1-189.
  • OHYAMA, H., YAMADA, T., OHKAWA, A. and WATANABE, I., 1985, Radiation-induced formation of apoptotic bodies in rat thymus. Radiation Research, 101, 123-130.
  • PALAYOOR, S. T., HUMM, J. L., ATCHBR, R. W., HINES, J. J. and MACKLIS, R. M., 1993, G2M arrest and apoptosis in murine T lymphoma cells following exposure to 212Bi alpha particle irradiation. Nuclear Medicine and Biology. 20, 795-805.
  • RADFORD, I. R., 1986, Evidence for a general relationship between the induced level of DNA double-strand breakge and cell-killing after X-irradiation of mammalian Cells. International Journal of Radiation Biology, 49, 611-620.
  • RADFORD, I. R. and MURFHY, T. K., 1994, Radiation response of mouse lymphoid and myeloid cell lines. Part III. Different signals can lead to apoptosis and may influence sensitivity to killing by DNA double-stand breakage. International Journal of Radiation Biology, 65, 229-239.
  • RAMAKRISHNAN, N., MCCLAIN, D. E. and CATRAVAS, G. N., 1993, Membranes as sensitive targets in thymocyte apoptosis. International Journal of Radiation Biology, 63, 693-701.
  • RITTER, M. A., CLEAVER, J. E. and TOBIAS, C. A., 1977, High-LET radiations induce a large proportion of non-rejoining DNA breaks. Nature, 266, 653-655.
  • ROOTS, R., YANG, T. C., CRAISE, L., BLAKELY, E. A. and TOBIAS, C. A., 1979, Impaired repair capacity of DNA breaks induced in mammalian cellular DNA by accelerated heavy ions. Radiation Research, 78, 38-49.
  • RYDBERG, B., LOBRICH, M. and COOPER, P K., 1994, DNA double-strand breaks induced by high-energy neon and iron ions in human fibroblasts. I. Pulsed-field gel electrophoresis method. Radiation Research, 139, 133-141.
  • STENERLOW, B., BLOMQUIST, E., GRUSELL, E., HARTMAN, T. and CARLSSON, J., 1996, Rejoining of DNA double-strand breaks induced by accelerated nitrogen ions. International Journal of Radiation Biology, 70, 413-420.
  • SUNGUROV, A. Y. and SHARLAEVA, T. M., 1988, Thymocyte membrane changes and modifications of interphase death. International Journal of Radiation Biology, 53, 501-506.
  • WARENIUS, H. M. and DOWN, J. D., 1995, RBE of fast neutrons for apoptosis in mouse thymocytes. International Journal of Radiation Biology, 68, 625-629.
  • WEBER, K. J. and FLENTIE, M., 1993, Lethality of heavy ion-induced DNA double-strand breaks in mammalian cells. International Journal of Radiation Biology, 64, 169-178.
  • WYLLIE, A. H., KERR, J. F. and CURRIE, A. R., 1980, Cell death: the Significance Of apoptosis. International Review of Cytology, 68, 251-306.

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