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Research Article

Epstein-Barr virus-transformed lymphoblastoid cell lines of ataxia telangiectasia patients are defective in X-ray-induced apoptosis

Pages 709-716 | Published online: 03 Jul 2009

  • BEAMISH, H., KHANNA, K. K. and LAVIN, M. F., 1994, Ionizing radiation and cell cycle progression in ataxia telangiectasia. Radiation Research, 138, S130-S133.
  • BEAMISH, H. and LAVIN, M. F., 1994, Radiosensitivity in ataxiatelangiectasia: anomalies in radiation-induced cell cycle delay. International Journal of Radiation Biology, 65, 175-184.
  • CANMAN, C. E., WOLFF, A. C., CHEN, C.-Y., FORNACE JR, A. J. and KASTAN, M. B., 1994, The p53-dependent Gl cell cycle checkpoint pathway and ataxia-telangiectasia. Cancer Research, 54, 5054-5058.
  • CASTRO, J., HEIDEN, T., WANG, N. and TRIBUKAIT, B., 1993, Preparation of cell nuclei from fresh tissues for highquality DNA flow cytometry. Cytometry, 14, 793-804.
  • DUCHAUD, E., RIDET, A., DELIC, Y., CUNDARI, E., MOUSTACCHI, E. and ROSSELLI, F., 1994, Changes in the radiationinduced apoptotic response in homozygotes and heterozygotes for the ataxia-telangiectasia gene. C R Acad Sd III, 317, 983-989.
  • DUCHAUD, E., RIDET, A., STOPPA-LYONNET, D., JANIN, N., MOUSTACCHI, E. and ROSSELLI, F., 1996, Deregulated apoptosis in ataxia telangiectasia: association with clinical stigmata and radiosensitivity. Cancer Research, 56, 1400-1404.
  • FORAY, N., PRIESTLEY, A., ALSBETH, G., BADIE, C., CAPULAS, E. P., ARLETT, C. F. and MALAISE, E. P., 1997, Hypersensitivity of ataxia telangiectasia fibroblasts to ionizing radiation is associated with repair deficiency of DNA double-strand breaks. International Journal of Radiation Biology, 72, 271-283.
  • FOTEDAR, R., DIEDRICH, L. and FOTEDAR, A., 1996, Apoptosis and the cell cycle. Progress in CellCycle Research, 2, 147-163.
  • HUMAR, B, MULLER, H. and SCOTT, R. J., 1997, Elevated frequency of p53-independent apoptosis after irradiation increases levels of DNA breaks in ataxia telangiectasia lymphoblasts. International Journal of Radiation Biology, 72, 257-269.
  • JORGENSEN, T. J. and SHILOH, Y., 1996, The ATM gene and the radiobiology of ataxia-telangiectasia. International Journal of Radiation Biology, 69, 527-537.
  • KASTAN, M. B, ZHAN, Q., EL-DEIRY, W. S., CARRIER, F., JACKS, T., WALSH, W. V., PLUNKETT, B. S., VOGELSTEIN, B. and FORNACE, A. J., 1992, A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxiatelangiectasia. Cell, 71, 587-597.
  • KHANNA, K. K., BEAMISH, H., YAN, J., HABSO, K., WILLIAMS, R., DUNN, I. and LAVIN, M. F., 1995, Nature of G1/S cell cycle checkpoint defect in ataxia-telangiectasia. Oncogme, 11, 609-618.
  • KHANNA, K. K. and LAVIN, M. F., 1993, Ionizing radiation and UV induction of p53 protein by different pathways in ataxia-telangiectasia cells. Oncogme, 8, 3307-3312.
  • LÜCKE-HUHLE, C., 1994, Alterations in oncogene expression and radiosensitivity in the most frequently used SV40-transformed human skin fibroblasts. International Journal of Radiation Biology, 65, 665-673.
  • MAITY, A., MCKENNA, W. G. and MUCHEL, R. J., 1994, The molecular basis for cell cycle delays following ionizing radiation: a review. Radiotherapy and Oncology, 31, 1-13.
  • MCKINNON, P. J., 1987, Ataxia-telangiectasia: an inherited disorder of ionizing-radiation sensitivity in man. Progress in the elucidation of the underlying biochemical defect. Human Genetics, 75, 197-208.
  • MEIIER, A. E., KRONQVIST, U.-S. E., LEWENSOHN, R. and HARMS-RINGDAHL, M., 1998, RBE for the induction of apoptosis in human peripheral lymphocytes exposed in vitro to high-LET radiation generated by accelerated nitrogen ions. International Journal of Radiation Biology, 73, 169-177.
  • MEYN, M. S., 1995, Ataxia-telangiectasia and cellular responses to DNA damage. Cancer Research, 55, 5991-6001.
  • MEYN, M.S., STRASPELD, L. and ALLEN, C., 1994, Testing the role of p53 in the expression of genetic instability and apoptosis in ataxia-telangiectasia. International Journal of Radiation Biology, 66, S141-S149.
  • PAINTER, R. B. and YOUNG, B. R., 1980, Radiosensitivity in ataxia-telangiectasia: a new explanation. Proceeding of the National Academy of Sciences, USA, 77, 7315-7317.
  • RUSSEL, J., WHELDON, T. E. and STANTON, P., 1995, A radioresistant variant derived from a human neuroblastoma cell line is less prone to radiation-induced apoptosis. Cancer Research, 55, 4915-4921.
  • SAVITSKY, K., BAR-SHIRA, A., GILAD, S., ROTMAN, G., ZIV, Y., VANAGAITE, L., TAGLE, D. A., SMITH, S., UZIEL, T., SFEZ, S., ASHKENAZI, M., PECKER, I., FRYDMAN, M., HARNIK, R., PATANIALI, S. R., SIMMONS, A., CLINES, G. A., SARTIEL, A., GATTI, R. A., CHESSA, L., SANAL, O., LAVIN, M. F., JASPERS, N. G. J., TAYLOR, A. M. R., ARLETT, C. F., MIKI, T., WEISSMAN, S. M., LOVETT, M., COLLINS, F. S. and SHILOH, Y., 1995, A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science, 268, 1749-1753.
  • SILES, E., VILLALOBOS, M., VALENZUELA, M. T., NUNEZ, M. I., GORDON, A., MCMILLAN, T. J., PEDRAZA, V. and RUIZ DE ALMODOVAR, J. M., 1996, Relationship between p53 status and radiosensitivity in human tumour cell lines. British Journal of Cancer, 73, 581-588.
  • SKOG, S., LEWENSOHN, R., HE, Q., BORG, A.-L. and GATTI, R., 1997, Kinetics of Gl/S and G2/M transition in X-irradiated ataxia-telangiectasia cells. Cancer Detection and Prevention, 21, 91-102.
  • VIDAIR, C. A., CHEN, C. H., LING, C. C. and DEWEY, W. C., 1996, Apoptosis induced by X-irradiation of rec-myc cells is postmitotic and not predicted by the time after irradiation or behaviour of sister cells. Cancer Research, 56, 4116-4118.
  • WALKER, P. R., KOKILEVA, L., LEBLANC, J. and SIKORSKA, M., 1993, Detection of the initial stages of DNA fragmentation in apoptosis. Bio Techniques, 15, 1032-1040.
  • WYLLIE, H., KERR, J. F. and CURRIE, A. R., 1980, Cell death: the significance of apoptosis. International Review of Cytology, 68, 251-306.
  • XIE, G., HABBERSETT, R. C., JIA, Y., PETERSON, S. R., LEHNERT, B. E., BRADBURY, E. M. and D'ANNA, J. A., 1998, Requirements for p53 and the ATM gene product in the regulation of Gl/S and S phase checkpoints. Oncogene, 16, 721-736.
  • ZHIVOTOVSKY, B, WADE, D., GAHM, A., ORRENIUS, S. and NICOTERA, P., 1994b, Formation of 50 kbp chromatin fragments in isolated liver nuclei is mediated by protease and endonuclease activation. FEBS Letters, 351, 150-154.
  • ZHIVOTOVSKY, B, WADE, D., NICOTERA, P. and ORRENIUS, S., 1994a, Role of nucleases in apoptosis. International Archive of Allergy and Immunology, 105, 333-338.

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