182
Views
28
CrossRef citations to date
0
Altmetric
Papers

Genetic variation in bitter taste and plasma markers of anti-oxidant status in college women

, PhD, , , &
Pages 35-45 | Published online: 13 Aug 2009

References

  • Al-Delaimy WK, Ferrari P, Slimani N, Pala V, Johansson I, Nilsson S. Plasma carotenoids as biomarkers of intake of fruits and vegetables: individual-level correlations in the European Prospective Investigation into Cancer and Nutrition (EPIC). Eur J Clin Nutr 2005; 59: 1387–1396
  • Anliker JA, Bartoshuk L, Ferris AM, Hooks LD. Children's food preferences and genetic sensitivity to the bitter taste of 6-n-propylthiouracil (PROP). Am J Clin Nutr 1991; 54: 316–320
  • Bartoshuk LM, Duffy VB, Miller IJ. PTC/PROP tasting: anatomy, psychophysics, and sex effects. Physiol Behav 1994; 56: 1165–1171
  • Basson MD, Bartoshuk LM, Dichello SZ, Panzini L, Weiffenbach JM, Duffy VB. Association between 6-n-propylthiouracil (PROP) bitterness and colonic neoplasms. Dig Dis Sci 2005; 50: 483–489
  • Bell KI, Tepper BJ. Short-term vegetable intake by young children classified by 6-n-propylthoiuracil bitter-taste phenotype. Am J Clin Nutr 2006; 84: 245–251
  • Block G, Norkus E, Hudes M, Mandel S, Helzlsouer K. Which plasma antioxidants are most related to fruit and vegetable consumption?. Am J Epidemiol 2001; 154: 1113–1118
  • Boyd WC. Taste reactions to antithyroid substances. Science 1950; 112: 153
  • Brevik A, Andersen LF, Karlsen A, Trygg KU, Blomhoff R, Drevon CA. Six carotenoids in plasma used to assess recommended intake of fruits and vegetables in a controlled feeding study. Eur J Clin Nutr 2004; 58: 1166–1173
  • Bruno RS, Leonard SW, Li J, Bray TM, Traber MG. Lower plasma alpha-carboxyethyl-hydroxychroman after deuterium-labeled alpha-tocopherol supplementation suggests decreased vitamin E metabolism in smokers. Am J Clin Nutr 2005; 81: 1052–1059
  • Casagrande SS, Wang Y, Anderson C, Gary TL. Have Americans increased their fruit and vegetable intake? The trends between 1988 and 2002. Am J Prev Med 2007; 32: 257–263
  • Dinehart ME, Hayes JE, Bartoshuk LM, Lanier SL, Duffy VB. Bitter taste markers explain variability in vegetable sweetness, bitterness, and intake. Physiol Behav 2006; 87: 304–313
  • Drayna D, Coon H, Kim UK, Elsner T, Cromer K, Otterud B, Baird L, Peiffer AP, Leppert M. Genetic analysis of a complex trait in the Utah Genetic Reference Project: a major locus for PTC taste ability on chromosome 7q and a secondary locus on chromosome 16p. Human Genetics 2003; 112: 567–572
  • Drewnowski A, Gomez-Carneros C. Bitter taste, phytonutrients, and the consumer: a review. Am J Clin Nutr 2000; 72: 1424–1435
  • Drewnowski A, Henderson SA, Hann CS, Shore AB. Taste responses to naringin, a flavonoid, and the acceptance of grapefruit juice are related to genetic sensitivity to 6-n-propylthiouracil. Am J Clin Nutr 1997; 66: 391–397
  • Drewnowski A, Henderson SA, Levine A, Hann C. Taste and food preferences as predictors of dietary practices in young women. Pub Health Nutr 1999; 2: 513–519
  • Drewnowski A, Henderson SA, Hann CS, Berg WA, Ruffin MT. Genetic taste markers and preferences for vegetables and fruit of female breast care patients. J Am Dietet Assoc 2000; 100: 191–197
  • Drewnowski A, Henderson SA, Cockroft JE. Genetic sensitivity to 6-n-propylthiouracil has no influence on dietary patterns, body mass indexes, or plasma lipid profiles of women. J Am Diet Assoc 2007; 107: 1340–1348
  • ESA Inc. 1996. Simultaneous analysis of carotenoids, retinoids, tocopherols, Vitamin K1, and Coenzyme-Q10 in plasma. Application Note #10-1176P. http://www.esainc.com/resources/literature/ ( Accessed 10 June 2008)
  • Fenwick GR, Heaney RK, Mullin WJ. Links Glucosinolates and their breakdown products in food and food plants. Crit Rev Food Sci Nutr. 1983; 18(2)123–201
  • Food and Nutrition Board. 2000. Dietary reference intakes for vitamin C, vitamin E, selenium, and carotinoids. Appendix F. National Academy of Sciences. Washington, DC: National Academy Press.
  • Ford ES, Sowell A. Serum alpha-tocopherol status in the United States population: findings from the Third National Health and Nutrition Examination Survey. Am J Epidemiol 1999; 150: 290–300
  • Ford ES, Schleicher RL, Mokdad AH, Ajani UA, Liu S. Distribution of serum concentrations of alpha-tocopherol and gamma-tocopherol in the US population. Am J Clin Nutr 2006; 84: 375–383
  • Fox AL. The relationship between chemical constitution and taste. Proc Natl Acad Sci USA 1932; 18: 115–120
  • Gao X, Wilde PE, Lichtenstein AH, Bermudez OI, Tucker KL. The maximal amount of dietary alpha-tocopherol intake in U.S. adults (NHANES 2001–2002). J Nutr 2006; 136: 1021–1026
  • Gao X, Qi L, Qiao N, Choi HK, Curhan G, Tucker KL, Ascherio A. Intake of added sugar and sugar-sweetened drink and serum uric acid concentration in US men and women. Hypertension 2007; 50: 306–312
  • Glanz K, Basil M, Maibach E, Goldberg J, Snyder D. Why Americans eat what they do: taste, nutrition, cost, convenience, and weight control concerns as influences on food consumption. J Am Diet Assoc 1998; 98: 1118–1126
  • Goldstein GL, Daun H, Tepper BJ. Adiposity in middle-aged women is associated with genetic taste blindness to 6-n-propylthiouracil. Obesity Res 2005; 13: 1017–1023
  • Green BG, Dalton P, Cowart B, Shaffer G, Rankin K, Higgins J. Evaluating the 'Labeled Magnitude Scale' for measuring sensations of taste and smell. Chem Senses 1996; 21: 323–334
  • Guo SW, Reed DR. The genetics of phenylthiocarbamide perception. Ann Hum Biol 2001; 28: 111–142
  • Jerzsa-Latta M, Krondl M, Coleman P. Use and perceived attributes of cruciferous vegetables in terms of genetically-mediated taste sensitivity. Appetite 1990; 15: 127–134
  • Kant AK. Nature of dietary reporting by adults in the third National Health and Nutrition Examination Survey, 1988–1994. J Am Coll Nutr 2002; 21: 315–327
  • Keller KL, Steinmann L, Nurse RJ, Tepper BJ. Genetic taste sensitivity to 6-n-propylthiouracil influences food preference and reported intake in preschool children. Appetite 2002; 38: 3–12
  • Kim UK, Jorgenson E, Coon H, Leppert M, Risch N, Drayna D. Positional cloning of the human quantitative trait locus underlying taste sensitivity to phenylthiocarbamide. Science 2003; 299: 1221–1225
  • Kirkmeyer SV, Tepper BJ. Understanding creaminess perception of dairy products using free-choice profiling and genetic responsivity to 6-n-propylthiouracil. Chem Senses 2003; 28: 527–536
  • Kirkmeyer SV, Tepper BJ. Consumer reactions to creaminess and genetic sensitivity to 6-n-propylthiouracil: a multidimentional study. Food Qual Pref 2005; 16: 545–556
  • Krebs-Smith SM, Heimendinger J, Patterson BH, Subar AF, Kessler R, Pivonka E. Psychosocial factors associated with fruit and vegetable consumption. Am J Health Promot 1995; 10: 98–104
  • Lykkesfeldt J, Loft S, Poulsen HE. Determination of ascorbic acid and dehydroascorbic acid in plasma by high-performance liquid chromatography with coulometric detection—are they reliable biomarkers of oxidative stress?. Anal Biochem 1995; 229: 329–335
  • MacCrehan WA. Determination of retinol, alpha-tocopherol, and beta-carotene in serum by liquid chromatography. Methods Enzymol 1990; 189: 172–181
  • Mattes R, Labov J. Bitter taste responses to phenylthiocarbamide are not related to dietary goitrogen intake in human beings. J Am Diet Assoc 1989; 89: 692–694
  • Mattes RD. 6-n-Propylthiouracil taster status: dietary modifier, marker or misleader?. Genetic variation in taste sensitivity. New York: Marcel Dekker, J Prescott, BJ Tepper, 2004; 229–250
  • Niculescu L, Stancu C, Sima A, Toporan D, Simionescu M. The total peroxyl radical trapping potential in serum—an assay to define the stage of atherosclerosis. J Cell Mol Med 2001; 5: 285–294
  • Nieswind A, Krondil M, Shrott M. Genetic influences on the selection of brassica vegetables by elderly individuals. NutrRes 1988; 8: 13–20
  • Prior RL, Wu X, Schaich K. Standardized methods for the determination of antioxidant capacity and phenolics in foods and dietary supplements. J Agric Food Chem 2005; 53: 4290–4302
  • Rautiainen S, Serafini M, Morgenstern R, Prior RL, Wolk A. The validity and reproducibility of food-frequency questionnaire-based total antioxidant capacity estimates in Swedish women. Am J Clin Nutr 2008; 87: 1247–1253
  • Sacerdote C, Guarrera S, Smith GD, Grioni S, Krogh V, Masala G, Mattiello A, Palli D, Panico S, Tumino R, Veglia F, Matullo G, Vineis P. Lactase persistence and bitter taste response: instrumental variables and mendelian randomization in epidemiologic studies of dietary factors and cancer risk. Am J Epidemiol 2007; 166: 576–581
  • Sandell MA, Breslin PA. Variability in a taste-receptor gene determines whether we taste toxins in food. Curr Biol 2006; 16: R792–R794
  • Scalbert A, Williamson G. Dietary intake and bioavailability of polyphenols. J Nutr 2000; 130: 2073S–2085S
  • Steiner JE, Glaser D., Hawilo M.E., Berridge K.C. Comparative expression of hedonic impact; affective reactions to taste by human infants and other primates. Neurosci Behav Rev 2001; 25: 53–74
  • Steinmetz KA, Potter JD. Vegetables, fruit, and cancer prevention: a review. J Am Diet Assoc 1996; 96: 1027–1039
  • Tepper BJ, Nurse RJ. Fat perception is related to PROP taster status. Physiol Behav 1997; 61: 949–954
  • Tepper BJ, Nurse RJ. PROP taster status is related to the perception and preference for fat. Ann NY Acad Sci 1998; 855: 802–804
  • Tepper BJ, Christensen CM, Cao J. Development of brief methods to classify individuals by PROP taster status. Physiol Behav 2001; 73: 571–577
  • Tepper BJ, Keller KL, Ullrich NV. Genetic variation in taste and preferences for bitter and pungent foods: Implications for chronic disease risk. Challenges in taste chemistry and biology. Symposium Series 867, TL Hofmann, CT Ho, W Pickenhagen. American Chemical Society, Washington, DC 2003; 60–74
  • Timpson NJ, Christensen M, Lawlor DA, Gaunt TR, Day IN, Ebrahim S, Davey Smith G. TAS2R38 (phenylthiocarbamide) haplotypes, coronary heart disease traits, and eating behavior in the British Women's Heart and Health Study. Am J Clin Nutr 2005; 81: 1005–1011
  • Timpson NJ, Heron J, Day IN, Ring SM, Bartoshuk LM, Horwood J, Emmett P, Davey-Smith G. Refining associations between TAS2R38 diplotypes and the 6-n-propylthiouracil (PROP) taste test: findings from the Avon Longitudinal Study of Parents and Children. BMC Genet 2007; 8: 51
  • Turnbull B, Matisoo-Smith E. Taste sensitivity to 6-n-propylthiouracil predicts acceptance of bitter-tasting spinach in 3–6-y-old children. Am J Clin Nutr 2002; 76: 1101–1105
  • USDA. 2005. Dietary Guidelines for Americans. Available online at: wwwhealthgov/dietaryguidelines/dga2005/document/defaulthtm. ( Accessed 10 June 08)
  • Valkonen M, Kuusi T. Spectrophotometric assay for total peroxyl radical-trapping antioxidant potential in human serum. J Lipid Res 1997; 38: 823–833
  • Wooding S, Kim UK, Bamshad MJ, Larsen J, Jorde LB, Drayna D. Natural selection and molecular evolution in PTC, a bitter-taste receptor gene. Am J Hum Genet 2004; 74: 637–646
  • World Health Organization. 2002. Report of a Joint WHO/FAO Expert Consultation. Report Series 916. World Health Organization & Food and Agriculture Organization of the United Nations. World Health Organization, GenevaSwitzerland.
  • Yackinous CA, Guinard JX. Relation between PROP (6-n-propylthiouracil) taster status, taste anatomy and dietary intake measures for young men and women. Appetite 2002; 38: 201–209
  • Zhao L, Kirkmeyer SV, Tepper BJ. A paper screening test to assess genetic taste sensitivity to 6-n-propylthiouracil. Physiol Behav 2003; 78: 625–633

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.