Meeting nutritional adequacy in the Brazilian population increases pesticide intake without exceeding chronic safe levels

References

• Agência Nacional de Vigilância Sanitária (ANVISA). 2016. Programa de Análise de Resíduos de Agrotóxicos em alimentos (PARA): Relatório das análises de amostras monitoradas no período de 2013 a 2015. Brasília; [accessed 2021 Dec 13]. https://www.gov.br/anvisa/pt-br/assuntos/agrotoxicos/programa-de-analise-de-residuos-em-alimentos/arquivos/3778json-file-1.
   Google Scholar
• Agência Nacional de Vigilância Sanitária (ANVISA). 2019. Programa de Análise de Resíduos de Agrotóxicos em alimentos (PARA): Relatório das amostras analisadas no período de 2017–2018 – Primeiro ciclo do plano plurianual 2017–2020. Brasília; [accessed 2021 Dec 13]. https://www.gov.br/anvisa/pt-br/assuntos/agrotoxicos/programa-de-analise-de-residuos-em-alimentos/arquivos/3770json-file-1.
   Google Scholar
• Aktar W, Sengupta D, Chowdhury A. 2009. Impact of pesticides use in agriculture: their benefits and hazards. Interdiscip Toxicol. 2(1):1–12.
   PubMedGoogle Scholar
• Bajwa U, Sandhu KS. 2014. Effect of handling and processing on pesticide residues in food- A review. J Food Sci Technol. 51(2):201–220.
   PubMed Web of Science ®Google Scholar
• Barré T, Vieux F, Perignon M, Cravedi JP, Amiot MJ, Micard V, Darmon N. 2016. Reaching nutritional adequacy does not necessarily increase exposure to food contaminants: evidence from a whole-diet modeling approach. J Nutr. 146(10):2149–2157.
   PubMed Web of Science ®Google Scholar
• Boedeker W, Watts M, Clausing P, Marquez E. 2020. The global distribution of acute unintentional pesticide poisoning: estimations based on a systematic review. BMC Public Health. 20(1):1875.
   PubMed Web of Science ®Google Scholar
• Bognár A. 2002. Tables on weight yield of food and retention factors of food constituents for the calculation of nutrient composition of cooked foods (Dishes). Karlsruhe: Federal Research Centre for Nutrition, Institute of Chemistry and Biology.
   Google Scholar
• Boobis AR, Ossendorp BC, Banasiak U, Hamey PY, Sebestyen I, Moretto A. 2008. Cumulative risk assessment of pesticide residues in food. Toxicol Lett. 180(2):137–150.
   PubMed Web of Science ®Google Scholar
• Bradman A, Quirós-Alcalá L, Castorina R, Schall RA, Camacho J, Holland NT, Barr DB, Eskenazi B. 2015. Effect of organic diet intervention on pesticide exposures in young children living in low-income urban and agricultural communities. Environ Health Perspect. 123(10):1086–1093.
   PubMed Web of Science ®Google Scholar
• Caldas ED, Tressou J, Boon PE. 2006. Dietary exposure of Brazilian consumers to dithiocarbamate pesticides – a probabilistic approach. Food Chem Toxicol. 44(9):1562–1571.
   PubMed Web of Science ®Google Scholar
• Carriquiry AL. 2003. Estimation of usual intake distributions of nutrients and foods. J Nutr. 133(2):601S–608S.
   PubMed Web of Science ®Google Scholar
• Darmon N, Drewnowski A. 2015. Contribution of food prices and diet cost to socioeconomic disparities in diet quality and health: a systematic review and analysis. Nutr Rev. 73(10):643–660.
   PubMed Web of Science ®Google Scholar
• Darmon N, Ferguson EL, Briend A. 2002. A cost constraint alone has adverse effects on food selection and nutrient density: an analysis of human diets by linear programming. J Nutr. 132(12):3764–3771.
   PubMed Web of Science ®Google Scholar
• De Rop J, Senaeve D, Jacxsens L, Houbraken M, van Klaveren J, Spanoghe P. 2019. Cumulative probabilistic risk assessment of triazole pesticides in Belgium from 2011 to 2014. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 36(6):911–921.
   PubMed Web of Science ®Google Scholar
• Defarge N, Spiroux de Vendômois J, Séralini GE. 2018. Toxicity of formulants and heavy metals in glyphosate-based herbicides and other pesticides. Toxicol Rep. 5:156–163.
   PubMed Web of Science ®Google Scholar
• Defarge N, Takács E, Lozano VL, Mesnage R, de Vendômois JS, Séralini GE, Székács A. 2016. Co-formulants in glyphosate-based herbicides disrupt aromatase activity in human cells below toxic levels. Int J Environ Res Public Health. 13(3):264.
   Web of Science ®Google Scholar
• Dos Santos Q, Sichieri R, Darmon N, Maillot M, Verly-Junior E. 2018. Food choices to meet nutrient recommendations for the adult Brazilian population based on the linear programming approach. Public Health Nutr. 21(8):1538–1545.
   PubMed Web of Science ®Google Scholar
• Eslami Z, Mahdavi V, Tajdar-Oranj B. 2021. Probabilistic health risk assessment based on Monte Carlo simulation for pesticide residues in date fruits of Iran. Environ Sci Pollut Res Int. 28(31):42037–42050.
   PubMed Web of Science ®Google Scholar
• European Commission. 2021. EU Pesticides database: Active substances, safeners and synergists; [accessed 2021 Dec 13]. https://ec.europa.eu/food/plant/pesticides/eu-pesticides-database/active-substances/?event=search.as.
   Google Scholar
• European Food Safety Authority (EFSA). 2009. Scientific opinion on risk assessment for a selected group of pesticides from the Triazole Group to test possible methodologies to assess cumulative effects from exposure through food from these pesticides on human health. Parma, Italy. Efsa J. 7:167. https://doi.org/https://doi.org/10.2903/j.efsa.2009.1167.
   Google Scholar
• European food safety authority (EFSA). 2012. Scientific opinion: guidance on the use of probabilistic methodology for modelling dietary exposure to pesticide residues. Efsa J. 10:39. https://doi.org/https://doi.org/10.2903/j.efsa.2012.2839.
   Google Scholar
• Food Research Center (FoRC), Universidade de São Paulo (USP) 2020. Tabela Brasileira de Composição de Alimentos (TBCA). São Paulo; [accessed 2012 Dec 13]. http://www.tbca.net.br.
   Google Scholar
• French SA. 2003. Pricing effects on food choices in journal of nutrition. Am Inst Nutr. 133(3):841S–843S. https://doi.org/https://doi.org/10.1093/jn/133.3.841s.
   PubMed Web of Science ®Google Scholar
• Gazan R, Brouzes CMC, Vieux F, Maillot M, Lluch A, Darmon N. 2018. Mathematical optimization to explore tomorrow’s sustainable diets: a narrative review. Adv Nutr. 9(5):602–616. https://doi.org/https://doi.org/10.1093/ADVANCES/NMY049.
   PubMed Web of Science ®Google Scholar
• Hyland C, Bradman A, Gerona R, Patton S, Zakharevich I, Gunier RB, Klein K. 2019. Organic diet intervention significantly reduces urinary pesticide levels in U.S. children and adults. Environ Res. 171:568–575. https://doi.org/https://doi.org/10.1016/j.envres.2019.01.024.
   PubMed Web of Science ®Google Scholar
• Institute of Medicine (IoM). 2000. Dietary reference intakes: applications in dietary assessment. Washington (DC): National Academies Press (US). https://doi.org/https://doi.org/10.17226/9956.
   Google Scholar
• Institute of Medicine (IoM). 2005. Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein, and amino acids. Washington (DC): National Academies Press. https://doi.org/https://doi.org/10.1016/s0002-8223(02)90346-9.
   Google Scholar
• Institute of Medicine (IoM). 2019. Dietary reference intakes for sodium and potassium. Washington (DC): National Academies Press (US). https://doi.org/https://doi.org/10.17226/25353.
   Google Scholar
• Instituto Brasileiro de Geografia e Estatística (IBGE). 2020. Pesquisa de orçamentos familiares 2017–2018: Análise do consumo alimentar pessoal no Brasil. Instituto Brasileiro de Geografia e Estatística, Rio de Janeiro ; [accessed 2012 Dec 13]. https://biblioteca.ibge.gov.br/visualizacao/livros/liv101742.pdf.
   Google Scholar
• Instituto Brasileiro do Meio Ambiente (IBAMA). 2018. Relatórios de Comercialização de Agrotóxicos. Instituto Brasileiro do Meio Ambiente e dos Recursos Naturais Renováveis ; [accessed 2012 Dec 13]. http://www.ibama.gov.br/agrotoxicos/relatorios-de-comercializacao-de-agrotoxicos.
   Google Scholar
• International Agency for Research on Cancer (IARC). 2019. IARC monographs on the identification of carcinogenic hazards to humans. Lyon; [accessed 2012 Dec 13]. https://monographs.iarc.who.int/monographs-available/.
   Google Scholar
• International Programme on Chemical Safety (IPCS). 2019. INCHEM: Internationally peer reviewed chemical safety information. Geneva; [accessed 2012 Dec 13]. http://www.inchem.org.
   Google Scholar
• International Programme on Chemical Safety (IPCS). 2020. Principles and methods for the risk assessment of chemicals in food. Chapter2. Environmental Health Criteria 240. WHO | International Programme on Chemical Safety; [accessed 2012 Dec 13]. http://www.who.int/foodsafety/publications/chemical-food/en/.
   Google Scholar
• Islam S, Colonescu C. 2019. Data on retail price differential between organic and conventional foods. Data Brief. 27:104641. https://doi.org/https://doi.org/10.1016/j.dib.2019.104641.
   PubMed Web of Science ®Google Scholar
• Jardim ANO, Mello DC, Goes FC, Frota Junior EF, Caldas ED. 2014. Pesticide residues in cashew apple, guava, kaki and peach: GC-μECD, GC-FPD and LC-MS/MS multiresidue method validation, analysis and cumulative acute risk assessment. Food Chem. 164:195–204. https://doi.org/https://doi.org/10.1016/j.foodchem.2014.05.030.
   PubMed Web of Science ®Google Scholar
• Jardim ANO, Brito AP, van Donkersgoed G, Boon PE, Caldas ED. 2018. Dietary cumulative acute risk assessment of organophosphorus, carbamates and pyrethroids insecticides for the Brazilian population. Food Chem Toxicol. 112:108–117. https://doi.org/https://doi.org/10.1016/j.fct.2017.12.010.
   PubMed Web of Science ®Google Scholar
• Jardim ANO, Mello DC, Brito AP, van der Voet H, Boon PE, Caldas ED. 2018. Probabilistic dietary risk assessment of triazole and dithiocarbamate fungicides for the Brazilian population. Food Chem Toxicol. 118:317–327. https://doi.org/https://doi.org/10.1016/j.fct.2018.05.002.
   PubMed Web of Science ®Google Scholar
• Jensen BH, Petersen A, Nielsen E, Christensen T, Poulsen ME, Andersen JH. 2015. Cumulative dietary exposure of the population of Denmark to pesticides. Food Chem Toxicol. 83:300–307. https://doi.org/https://doi.org/10.1016/j.fct.2015.07.002.
   PubMed Web of Science ®Google Scholar
• Joint FAO/WHO Meeting on Pesticide Residues (JMPR). 1994. Pesticide Residues in Food – 1993 (JMPR Evaluations). Part II. Toxicological. Geneva, Switzerland: World Health Organization.
   Google Scholar
• Joint FAO/WHO Meeting on Pesticide Residues (JMPR). 2018. Pesticide residues in food -2018: toxicological evaluations (Part II). Joint Meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Core Assessment Group on Pesticide Residues. Berlin, Germany; [accessed 2012 Dec 13]. https://apps.who.int/iris/bitstream/handle/10665/325787/9789241655330-eng.pdf.
   Google Scholar
• Kaushik G, Satya S, Naik SN. 2009. Food processing a tool to pesticide residue dissipation – a review. Food Res Int. 42(1):26–40.
   Web of Science ®Google Scholar
• Lu C, Toepel K, Irish R, Fenske RA, Barr DB, Bravo R. 2006. Organic diets significantly lower children’s dietary exposure to organophosphorus pesticides. Environ Health Perspect. 114(2):260–263. https://doi.org/https://doi.org/10.1289/ehp.8418.
   PubMed Web of Science ®Google Scholar
• Maillot M, Vieux F, Amiot MJ, Darmon N. 2010. Individual diet modeling translates nutrient recommendations into realistic and individual-specific food choices. Am J Clin Nutr. 91(2):421–430. https://doi.org/https://doi.org/10.3945/ajcn.2009.28426.
   PubMed Web of Science ®Google Scholar
• Maillot M, Vieux F, Delaere F, Lluch A, Darmon N. 2017. Dietary changes needed to reach nutritional adequacy without increasing diet cost according to income: an analysis among French adults. PLoS One. 12(3):e0174679. https://doi.org/https://doi.org/10.1371/journal.pone.0174679.
   PubMed Web of Science ®Google Scholar
• Mesnage R, Bernay B, Séralini GE. 2013. Ethoxylated adjuvants of glyphosate-based herbicides are active principles of human cell toxicity. Toxicology. 313(2–3):122–128. https://doi.org/https://doi.org/10.1016/j.tox.2012.09.006.
   PubMed Web of Science ®Google Scholar
• Ministério da Agricultura, Pecuária e Abastecimento (MAPA) 2021. Agrotóxicos: Informações técnicas. Brazil; [accessed 2012 Dec 13]. https://www.gov.br/agricultura/pt-br/assuntos/insumos-agropecuarios/insumos-agricolas/agrotoxicos/informacoes-tecnicas.
   Google Scholar
• Moshfegh AJ, Rhodes DG, Baer DJ, Murayi T, Clemens JC, Rumpler WV, Paul DR, Sebastian RS, Kuczynski KJ, Ingwersen LA, et al. 2008. The US department of agriculture automated multiple-pass Method reduces bias in the collection of energy intakes. Am J Clin Nutr. 88(2):324–332. https://doi.org/https://doi.org/10.1093/ajcn/88.2.324.
   PubMed Web of Science ®Google Scholar
• Pires MV. 2013. Development and use of a database for conducting chronic dietary risk assessment of pesticides [Master Dissertation] Universidade de Londrina, Londrina, Brazil. http://www.toxicologia.unb.br/?pg=textos&id=35&nome=Disserta%E7FSes%20e20%Teses.
   Google Scholar
• Quijano L, Yusà V, Font G, Pardo O. 2016. Chronic cumulative risk assessment of the exposure to organophosphorus, carbamate and pyrethroid and pyrethrin pesticides through fruit and vegetables consumption in the region of Valencia (Spain). Food Chem Toxicol. 89:39–46. https://doi.org/https://doi.org/10.1016/j.fct.2016.01.004.
   PubMed Web of Science ®Google Scholar
• Sieke C, Michalski B, Kuhl T. 2018. Probabilistic dietary risk assessment of pesticide residues in foods for the German population based on food monitoring data from 2009 to 2014. J Expo Sci Environ Epidemiol. 28(1):46–54. https://doi.org/https://doi.org/10.1016/j.fct.2018.09.010.
   PubMed Web of Science ®Google Scholar
• United States Environmental Protection Agency (USEPA). 2002. Guidance on cumulative risk assessment of pesticide chemicals that have a common mechanism of toxicity. Washington, D.C.; [accessed 2012 Dec 13]. https://www.epa.gov/sites/production/files/2015-07/documents/guidance_on_common_mechanism.pdf.
   Google Scholar
• United States Environmental Protection Agency (USEPA). 2006. Metconazole human health risk assessments for the section 18 Request for Control of Soybean Rust on Soybeans. Office of Pesticide Programs U.S. Environmental Protection Agency, Washington. D.C.; [accessed 2012 Dec 13]. https://www3.epa.gov/pesticides/chem_search/cleared_reviews/csr_PC-125619_19-Apr-06_a.pdf.
   Google Scholar
• Vanlaeys A, Dubuisson F, Seralini G-E, Travert C. 2018. Formulants of glyphosate-based herbicides have more deleterious impact than glyphosate on TM4 Sertoli cells. Toxicol. Vitr. 52:14–22. https://doi.org/https://doi.org/10.1016/j.tiv.2018.01.002.
   PubMed Web of Science ®Google Scholar
• Verly-Jr E, Darmon N, Sichieri R, Sarti FM. 2020. Reaching culturally acceptable and adequate diets at the lowest cost increment according to income level in Brazilian households. PLoS One. 15(3):e0229439. https://doi.org/https://doi.org/10.1371/journal.pone.0229439.
   PubMed Web of Science ®Google Scholar
• Verly Jr E, Marchioni DM, Araujo MC, Carli E, Oliveira D CRS, Yokoo EM, Sichieri R, Pereira RA. Forthcoming 2021. december. Evolution of energy and nutrient intake in Brazil between 2008–2009 and 2017–2018. Rev Saude Publica. 55(1):5s. https://doi.org/https://doi.org/10.11606/s1518-8787.2021055003343.
   Google Scholar
• Verly-Jr E, Sichieri R, Darmon N, Maillot M, Sarti FM. 2019. Planning dietary improvements without additional costs for low-income individuals in Brazil: linear programming optimization as a tool for public policy in nutrition and health. Nutr. J. 18(1):40. https://doi.org/https://doi.org/10.1186/s12937-019-0466-y.
   PubMedGoogle Scholar
• Verly-Jr E, Pereira ADS, Marques ES, Horta PM, Canella DS, Cunha DB. 2020. Reducing ultra-processed foods and increasing diet quality in affordable and culturally acceptable diets: a study case from Brazil using linear programming. Br J Nutr. 126(4):572–581. https://doi.org/https://doi.org/10.1017/S0007114520004365.
   PubMed Web of Science ®Google Scholar
• World Health Organization (WHO). 2003. Joint FAO/WHO expert consultation: diet, nutrition, and the prevention of chronic diseases. World Health Organization. Geneva, Switzerland.
   Google Scholar