Limosilactobacillus reuteri BIO7251 administration improves metabolic phenotype in obese mice fed a high fat diet: an inter-organ crosstalk between gut, adipose tissue and nervous system

References

• Abot A, Fried S, Cani PD, Knauf C. 2022. Reactive oxygen species/reactive nitrogen species as messengers in the gut: impact on physiology and metabolic disorders. Antioxid Redox Signal. 37(4–6):394–415. doi: 10.1089/ars.2021.0100.
   PubMed Web of Science ®Google Scholar
• Abot A, Lucas A, Bautzova T, Bessac A, Fournel A, Le-Gonidec S, Valet P, Moro C, Cani PD, Knauf C. 2018. Galanin enhances systemic glucose metabolism through enteric nitric oxide synthase-expressed neurons. Mol Metab. 10:100–108. doi: 10.1016/j.molmet.2018.01.020.
   PubMed Web of Science ®Google Scholar
• Abot A, Wemelle E, Laurens C, Paquot A, Pomie N, Carper D, Bessac A, Mas Orea X, Fremez C, Fontanie M, et al. 2021. Identification of new enterosynes using prebiotics: roles of bioactive lipids and mu-opioid receptor signalling in humans and mice. Gut. 70(6):1078–1087. doi: 10.1136/gutjnl-2019-320230.
   PubMed Web of Science ®Google Scholar
• Abuqwider J, Altamimi M, Mauriello G. 2022. Limosilactobacillus reuteri in health and disease. Microorganisms. 10(3):522. doi: 10.3390/microorganisms10030522.
   PubMed Web of Science ®Google Scholar
• Asadi A, Shadab Mehr N, Mohamadi MH, Shokri F, Heidary M, Sadeghifard N, Khoshnood S. 2022. Obesity and gut-microbiota-brain axis: a narrative review. J Clin Lab Anal. 36(5):e24420. doi: 10.1002/jcla.24420.
   PubMed Web of Science ®Google Scholar
• Cani PD. 2019. Microbiota and metabolites in metabolic diseases. Nat Rev Endocrinol. 15(2):69–70. doi: 10.1038/s41574-018-0143-9.
   PubMed Web of Science ®Google Scholar
• Cani PD, Knauf C. 2021. A newly identified protein from Akkermansia muciniphila stimulates GLP-1 secretion. Cell Metab. 33(6):1073–1075. doi: 10.1016/j.cmet.2021.05.004.
   PubMed Web of Science ®Google Scholar
• Cani PD, Knauf C. 2016. How gut microbes talk to organs: the role of endocrine and nervous routes. Mol Metab. 5(9):743–752. doi: 10.1016/j.molmet.2016.05.011.
   PubMed Web of Science ®Google Scholar
• Cani PD, Van Hul M, Lefort C, Depommier C, Rastelli M, Everard A. 2019. Microbial regulation of organismal energy homeostasis. Nat Metab. 1(1):34–46. doi: 10.1038/s42255-018-0017-4.
   PubMedGoogle Scholar
• Challet E. 2019. The circadian regulation of food intake. Nat Rev Endocrinol. 15(7):393–405. doi: 10.1038/s41574-019-0210-x.
   PubMed Web of Science ®Google Scholar
• Choi SI, You S, Kim S, Won G, Kang CH, Kim GH. 2021. Weissella cibaria MG5285 and Lactobacillus reuteri MG5149 attenuated fat accumulation in adipose and hepatic steatosis in high-fat diet-induced C57BL/6J obese mice. Food Nutr Res. 65(8087):1–11. doi: 10.29219/fnr.v65.8087.
   Google Scholar
• Cui Y, Qi S, Zhang W, Mao J, Tang R, Wang C, Liu J, Luo XM, Wang H. 2019. Lactobacillus reuteri ZJ617 culture supernatant attenuates acute liver injury induced in mice by lipopolysaccharide. J Nutr. 149(11):2046–2055. doi: 10.1093/jn/nxz088.
   PubMed Web of Science ®Google Scholar
• de Vos WM, Tilg H, Van Hul M, Cani PD. 2022. Gut microbiome and health: mechanistic insights. Gut. 71(5):1020–1032. doi: 10.1136/gutjnl-2021-326789.
   PubMed Web of Science ®Google Scholar
• Fournel A, Drougard A, Duparc T, Marlin A, Brierley SM, Castro J, Le-Gonidec S, Masri B, Colom A, Lucas A, et al. 2017. Apelin targets gut contraction to control glucose metabolism via the brain. Gut. 66(2):258–269. doi: 10.1136/gutjnl-2015-310230.
   PubMed Web of Science ®Google Scholar
• Knauf C, Abot A, Wemelle E, Cani PD. 2020. Targeting the enteric nervous system to treat metabolic disorders? ‘Enterosynes’ as therapeutic gut factors. Neuroendocrinology. 110(1–2):139–146. doi: 10.1159/000500602.
   PubMed Web of Science ®Google Scholar
• Paschos GK, Ibrahim S, Song WL, Kunieda T, Grant G, Reyes TM, Bradfield CA, Vaughan CH, Eiden M, Masoodi M, et al. 2012. Obesity in mice with adipocyte-specific deletion of clock component Arntl. Nat Med. 18(12):1768–1777. doi: 10.1038/nm.2979.
   PubMed Web of Science ®Google Scholar
• Plovier H, Everard A, Druart C, Depommier C, Van Hul M, Geurts L, Chilloux J, Ottman N, Duparc T, Lichtenstein L, et al. 2017. A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice. Nat Med. 23(1):107–113. doi: 10.1038/nm.4236.
   PubMed Web of Science ®Google Scholar
• Rastelli M, Cani PD, Knauf C. 2019. The gut microbiome influences host endocrine functions. Endocr Rev. 40(5):1271–1284. doi: 10.1210/er.2018-00280.
   PubMed Web of Science ®Google Scholar
• Rastelli M, Knauf C, Cani PD. 2018. Gut microbes and health: a focus on the mechanisms Linking microbes, obesity, and related disorders. Obesity. 26(5):792–800. doi: 10.1002/oby.22175.
   PubMed Web of Science ®Google Scholar
• Sababi M, Bengtsson UH. 2001. Enhanced intestinal motility influences absorption in anaesthetized rat [comparative study]. Acta Physiol Scand. 172(2):115–122. doi: 10.1046/j.1365-201X.2001.00849.x.
   PubMedGoogle Scholar
• Simon MC, Strassburger K, Nowotny B, Kolb H, Nowotny P, Burkart V, Zivehe F, Hwang JH, Stehle P, Pacini G, et al. 2015. Intake of Lactobacillus reuteri improves incretin and insulin secretion in glucose-tolerant humans: a proof of concept. Diabetes Care. 38(10):1827–1834. doi: 10.2337/dc14-2690.
   PubMed Web of Science ®Google Scholar
• Van Hul M, Cani PD. 2019. Targeting carbohydrates and polyphenols for a healthy microbiome and healthy weight. Curr Nutr Rep. 8(4):307–316. doi: 10.1007/s13668-019-00281-5.
   PubMedGoogle Scholar
• Van Hul M, Cani PD. 2023. The gut microbiota in obesity and weight management: microbes as friends or foe? Nat Rev Endocrinol. 19(5):258–271. doi: 10.1038/s41574-022-00794-0.
   PubMed Web of Science ®Google Scholar
• Van Hul M, Geurts L, Plovier H, Druart C, Everard A, Stahlman M, Rhimi M, Chira K, Teissedre PL, Delzenne NM, et al. 2018. Reduced obesity, diabetes, and steatosis upon cinnamon and grape pomace are associated with changes in gut microbiota and markers of gut barrier. Am J Physiol Endocrinol Metab. 314(4):E334–E352. doi: 10.1152/ajpendo.00107.2017.
   PubMed Web of Science ®Google Scholar
• Wemelle E, Carneiro L, Abot A, Lesage J, Cani PD, Knauf C. 2022. glucose stimulates gut Motility in fasted and fed conditions: potential involvement of a nitric oxide pathway. Nutrients. 14(10):2176. doi: 10.3390/nu14102176.
   PubMed Web of Science ®Google Scholar
• Yoon HS, Cho CH, Yun MS, Jang SJ, You HJ, Kim JH, Han D, Cha KH, Moon SH, Lee K, et al. 2021. Akkermansia muciniphila secretes a glucagon-like peptide-1-inducing protein that improves glucose homeostasis and ameliorates metabolic disease in mice. Nat Microbiol. 6(5):563–573. doi: 10.1038/s41564-021-00880-5.
   PubMed Web of Science ®Google Scholar