747
Views
78
CrossRef citations to date
0
Altmetric
Research Article

Lipoplex size determines lipofection efficiency with or without serum

, , , , &
Pages 35-43 | Published online: 09 Jul 2009

References

  • Caplen, N.J., Alton, E.W.F.W., Middelton, P.G., Dorin, J.R., Stevenson, B.J., Gao, X., Durham, S.R., Jeffery, P.K., Hodson, M.E., Coutelle, C., Huang, L., Porteous, D.J., Williamson, R. and Geddes, D.M., 1995, Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis. Natural Medicine, 1, 39 - 46.
  • Chesnoy, S. and Huang, L., 2000, Structure and function of lipid- DNA complexes for gene delivery. Annual Review of Biophysics Biomolecular Structures, 29, 27 - 47.
  • Crystal, R., 1995, Transfer of genes to humans: early lessons and obstacles to success. Science, 270, 404 - 410.
  • Dean, M.N. and McKay, R., 1994, Inhibition of protein kinase C-alpha expression in mice after systemic administration of phosphor- othioate antisense oligodeoxynucleotides. Proceedings of the National Academy of Science (USA) 91, 11762- 11766.
  • Escriou, V., Ciolina, C., Lacroix, F., Byk, G., Scherman, D., 1998, Cationic lipid-mediated gene transfer: effect of serum on cellular uptake and intracellular fate of lipopolyamine/DNA complexes. Biochimica Biophysica Acta, 1368, 276 - 288.
  • Fasbender, A., Marshall, J., Moninger, T.O., Grunst, T., Cheng, S. and Welsh, M.J., 1997, Effect of co-lipids in enhancing cationic lipid-mediated gene transfer in vitro and in vivo. <i>Gene Therapy, 4, 716 - 725.
  • Felgner, P.L., Gadek, T.R., Holm, M., Roman, R., Chan, H.W., Wenz, M., Northrop J.P., Ringold G.M. and Danielsen M., 1987, Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proceedings of the National Academy of Sciences USA, 84, 7413- 7417.
  • Felgner, P.L., Tsai, Y.J., Sukhu, L., Wheeler, C.J., Manthrope, M., Marshal, J. and Chen, S.H., 1995, Improved cationic lipid formulations for in vivo gene therapy. Annals of the New York Academy of Science, 772, 126 - 139.
  • Gershon, H., Ghirlando, R., Guttman, S.B. and Minsky, A., 1993, Mode of formation and structural features of DNA-cationic liposome complexes used for transfection. Biochemistry, 32, 7143- 7151.
  • Huang, L. and Viroonchatapan, E. 1999, Introduction. In Nonviral Vector for Gene Therapy, L. Huang, M.C. Hung and E. Wagner, eds (San Diego, USA: Academic Press) pp. 4 - 17.
  • Hyde, S.C., Gil, D.R., Higgind, C.F., Trezise, A.E., Macvinish, L.J., Cuthbert, A.W., Ratcliff, R., Evance, M.J. and Coledged, W.H., 1993, Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy. Nature, 362, 250 - 255.
  • Kikuchi, A., Aoki, Y., Sugaya, S., Serikawa, T., Takakuwa, K., Tanaka, K., Suzuki, N. and Kikuchi, H., 1999, Development of novel cationic liposomes for efficient gene transfer into peritoneal disseminated tumor. Human Gene Therapy, 10, 947 - 955.
  • Lappalainen, K., Jaaskelainen, I., Syrjanen, K., Urtti, A. and Syrjanen, S., 1994, Comparison of cell proliferation and toxicity assays using two cationic liposomes. Pharmacuetical Research, 11, 1127- 1131.
  • Lasic, D.D. and Templeton, N.S., 1996, Liposomes in gene therapy. Advanced Drug Delivery Reviews, 20, 221 - 266.
  • Lee, R.J. and Huang, L., 1997, Lipidic vector systems for gene transfer. Critical Reviews in Therapeutic Drug Carrier Systems, 14, 173 - 206.
  • Liu, Y., Liggitt, D., Zhong, W., Tu, G., Gaensler, K. and Debs, R., 1995, Cationic liposome-mediated intravenous gene delivery. Journal of Biological Chemistry,270, 24864- 24870.
  • Matsui, H., Johnson, L.G., Randell, S.H. and Boucher, R.C., 1997, Loss of binding and entry of liposome-DNA complexes decreases transfection efficiency in differentiated airway epithelial cells. Journal of Biochemical Chemistry, 272, 1117- 1126.
  • Morgan, R.A. and Anderson, W.F., 1993, Human gene therapy. Annual Review of Biochemistry, 62, 191 - 217.
  • Nabel, G.J., Nabel, E.G., Yang, Z., Fox, B.A., Gao, X., Huang, L. and Chang, A.E., 1993, Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans. Proceedings of the National Academy of Science (USA), 90, 11307- 11311.
  • Pires, P., Simoes, S., Nir, S., Gaspar, R., Duzgunes, N. and Pedroso de Lima, M.C., 1999, Interaction of cationic liposomes and their DNA complexes with monocytic leukemia cells. Biochimica et Biophysica Acta, 1418, 71 - 84.
  • Ross, P.C. and Hui, S.W., 1999, Lipoplex size is a major determinant of in vitro lipofection efficiency, Gene Therapy, 6, 651 - 659.
  • Sakurai, F., Inoue, R., Nishino, Y., Okuda A., Matsumoto, O., Taga, T., Yamashita, F., Takakura, Y. and Hashida, M., 2000, Effect of DNA/liposome mixing ratio on the physicochemical characteris- tics, cellular uptake and intracellular trafficking of plasmid DNA/ cationic liposome complexes and subsequent gene expression. Jouranl of Controlled Release, 66, 255 - 269.
  • Sternberg, B., Sorgi, F.L. and Huang, L., 1994, New structures in complex formation between DNA and cationic liposomes visua- lized by freeze-fracture electron microscopy. FEBS Letters, 356, 361 - 366.
  • Taneja, S.S., Pang, S., Cohan, P. and Belldegrun, A., 1997, Gene therapy: principles and potential. Cancer Survival, 23, 247 - 266. Thierry, A.R., Lunardi-Iskandar, Y., Bryant, J.L., Rabinovich, P., Gallo, R.C. and Mahan, L.C., 1995, Systemic gene therapy: biodistribution and long-term expression of a transgene in mice. Proceedings of the National Academy of Science (USA), 92, 9742- 9746.
  • Tolstoshev, P., 1993, Gene therapy, concepts, current trials and future directions. Annual Review of Pharmacology and Toxicol- ogy, 33, 573 - 596.
  • Wheeler, C. J., Sukhu, L., Yang, G., Tsai, Y., Bustamente, C., Felgner, P., Norman, J. and Manthorpe, M., 1996. Converting an alcohol to an amine in a cationic lipid dramatically alters the co- lipid requirement, cellular transfection activity and the ultrastruc- ture of DNA-cytofectin complexes. Biochimica et Biophysica Acta, 1280, 1 - 11.
  • Wrobel, I. and Collins, D., 1995, Fusion of cationic liposomes with mammalian cells occurs after endocytosis. Biochimica et Biophy- sica Acta, 1235, 296 - 304.
  • Xu, Y. and Szoka, F.C.Jr., 1996, Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. Biochemistry, 35, 5616 - 5623.
  • Zhu, N., Liggitt, D., Liu, Y. and Debs, R., 1993, Systemic gene expression after intravenous DNA delivery into adult mice. Science, 261, 209 - 211.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.