Two splice variants derived from a Drosophila melanogaster candidate ClC gene generate ClC-2-type Cl⁻ channels

References

• Accardi A, Miller C. Secondary active transport mediated by a prokaryotic homologue of ClC Cl− channels. Nature 2004; 427: 803–807
   PubMed Web of Science ®Google Scholar
• Asmild M, Willumsen NJ. Chloride channels in the plasma membrane of a foetal Drosophila cell line, S2. Pflugers Arch 2000; 439: 759–764
   Google Scholar
• Barry PH. JPCalc, a software package for calculating liquid junction potential corrections in patch-clamp, intracellular, epithelial and bilayer measurements and for correcting junction potential measurements. J Neurosci Meth 1994; 51: 107–116
   PubMed Web of Science ®Google Scholar
• Bennetts B, Rychkov GY, Ng HL, Morton CJ, Stapleton D, Parker MW, Cromer BA. Cytoplasmic ATP-sensing domains regulate gating of skeletal muscle ClC-1 chloride channels. J Biol Chem 2005; 280: 32452–32458
   PubMed Web of Science ®Google Scholar
• Bösl MR, Stein V, Hubner C, Zdebik AA, Jordt SE, Mukhopadhyay AK, Davidoff MS, Holstein AF, Jentsch TJ. Male germ cells and photoreceptors, both dependent on close cell-cell interactions, degenerate upon ClC-2 Cl− channel disruption. EMBO J 2001; 20: 1289–1299
   PubMed Web of Science ®Google Scholar
• Celniker SE, Rubin GM. The Drosophila melanogaster genome. Annu Rev Genomics Hum Genet 2003; 4: 89–117
   PubMed Web of Science ®Google Scholar
• Cid LP, Niemeyer MI, Ramírez A, Sepúlveda FV. Splice variants of a ClC-2 chloride channel with differing functional characteristics. Am J Physiol 2000; 279: C1198–C1210
   Google Scholar
• Cid, LP, Niemeyer, MI, Sepúlveda, FV. 2006. ClC-2 channels get new partners. Focus on ‘Association between Hsp90 and the ClC-2 chloride channel upregulates chanel function’. Am J Physiol, 290:C45–C56.
   Google Scholar
• Díaz M, Sepúlveda FV. Characterisation of Ca2 + -dependent inwardly rectifying K+ currents in HeLa cells. Pflügers Arch 1995; 430: 168–180
   Google Scholar
• Dow JT, Davies SA. Integrative physiology and functional genomics of epithelial function in a genetic model organism. Physiol Rev 2003; 83: 687–729
   Google Scholar
• Dutzler R, Campbell EB, Cadene M, Chait BT, MacKinnon R. X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity. Nature 2002; 415: 287–294
   PubMed Web of Science ®Google Scholar
• Dutzler R, Campbell EB, MacKinnon R. Gating the selectivity filter in ClC chloride channels. Science 2003; 300: 108–112
   PubMed Web of Science ®Google Scholar
• Estévez R, Pusch M, Ferrer-Costa C, Orozco M, Jentsch TJ. Functional and structural conservation of CBS domains from CLC chloride channels. J Physiol 2004; 557: 363–378
   PubMed Web of Science ®Google Scholar
• Gisselmann G, Plonka J, Pusch H, Hatt H. Unusual functional properties of homo- and heteromultimeric histamine-gated chloride channels of Drosophila melanogaster: spontaneous currents and dual gating by GABA and histamine. Neurosci Lett 2004; 372: 151–156
   Google Scholar
• Gisselmann G, Pusch H, Hovemann BT, Hatt H. Two cDNAs coding for histamine-gated ion channels in D. melanogaster. Nat Neurosci 2002; 5: 11–12
   PubMedGoogle Scholar
• Hebeisen S, Biela A, Giese B, Muller-Newen G, Hidalgo P, Fahlke C. The role of the carboxyl terminus in ClC chloride channel function. J Biol Chem 2004; 279: 13140–13147
   PubMed Web of Science ®Google Scholar
• Henderson JE, Knipple DC, Soderlund DM. PCR-based homology probing reveals a family of GABA receptor-like genes in Drosophila melanogaster. Insect Biochem Mol Biol 1994; 24: 363–371
   Google Scholar
• Hinzpeter, A, Lipecka, J, Brouillard, F, Baudouin-Legros, M, Dadlez, M, Edelman, A, Fritsch, J. 2006. Association between HSP90 and the ClC-2 chloride channel upregulates channel function. Am J Physiol, 290:C45–56.
   Google Scholar
• Iyer R, Iverson TM, Accardi A, Miller C. A biological role for prokaryotic ClC chloride channels. Nature 2002; 419: 715–718
   PubMed Web of Science ®Google Scholar
• Jentsch TJ, Poet M, Fuhrmann JC, Zdebik AA. Physiological functions of CLC Cl− channels gleaned from human genetic disease and mouse models. Annu Rev Physiol 2005; 67: 779–807
   PubMedGoogle Scholar
• Jentsch TJ, Stein V, Weinreich F, Zdebik AA. Molecular structure and physiological function of chloride channels. Physiol Rev 2002; 82: 503–568
   PubMed Web of Science ®Google Scholar
• Kane NS, Hirschberg B, Qian S, Hunt D, Thomas B, Brochu R, Ludmerer SW, Zheng Y, Smith M, Arena JP, Cohen CJ, Schmatz D, Warmke J, Cully DF. Drug-resistant Drosophila indicate glutamate-gated chloride channels are targets for the antiparasitics nodulisporic acid and ivermectin. Proc Natl Acad Sci USA 2000; 97: 13949–13954
   PubMed Web of Science ®Google Scholar
• Kearney JB, Wheeler SR, Estes P, Parente B, Crews ST. Gene expression profiling of the developing Drosophila CNS midline cells. Dev Biol 2004; 275: 473–492
   PubMed Web of Science ®Google Scholar
• Lee D, Su H, O'Dowd DK. GABA receptors containing Rdl subunits mediate fast inhibitory synaptic transmission in Drosophila neurons. J Neurosci 2003; 23: 4625–4634
   Google Scholar
• Niemeyer MI, Cid LP, Zúñiga L, Catalán M, Sepúlveda FV. A conserved pore-lining glutamate as a voltage- and chloride-dependent gate in the ClC-2 chloride channel. J Physiol 2003; 553: 873–879
   PubMedGoogle Scholar
• Niemeyer MI, Yusef YR, Cornejo I, Flores CA, Sepúlveda FV, Cid LP. Functional evaluation of human ClC-2 chloride channel mutations associated with idiopathic generalized epilepsies. Physiol Genomics 2004; 19: 74–83
   PubMed Web of Science ®Google Scholar
• Peña-Münzenmayer G, Catalán M, Cornejo I, Figueroa CD, Melvin JE, Niemeyer MI, Cid LP, Sepúlveda FV. Basolateral localization of native ClC-2 chloride channels in absorptive intestinal epithelial cells and basolateral sorting encoded by a CBS-2 domain di-leucine motif. J Cell Sci 2005; 118: 4243–4252
   PubMed Web of Science ®Google Scholar
• Picollo A, Pusch M. Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5. Nature 2005; 436: 420–423
   PubMed Web of Science ®Google Scholar
• Scheel O, Zdebik AA, Lourdel S, Jentsch TJ. Voltage-dependent electrogenic chloride/proton exchange by endosomal CLC proteins. Nature 2005; 436: 424–427
   PubMed Web of Science ®Google Scholar
• Schnizler K, Saeger B, Pfeffer C, Gerbaulet A, Ebbinghaus-Kintscher U, Methfessel C, Franken EM, Raming K, Wetzel CH, Saras A, Pusch H, Hatt H, Gisselmann G. A novel chloride channel in Drosophila melanogaster is inhibited by protons. J Biol Chem 2005; 280: 16254–16262
   Google Scholar
• Scott JW, Hawley SA, Green KA, Anis M, Stewart G, Scullion GA, Norman DG, Hardie DG. CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations. J Clin Invest 2004; 113: 274–284
   PubMed Web of Science ®Google Scholar
• Staley K, Smith R, Schaack J, Wilcox C, Jentsch TJ. Alteration of GABAA receptor function following gene transfer of the ClC-2 chloride channel. Neuron 1996; 17: 543–551
   PubMedGoogle Scholar
• Suzuki M, Mizuno A. A novel human Cl− channel family related to Drosophila flightless locus. J Biol Chem 2004; 279: 22461–22468
   PubMed Web of Science ®Google Scholar
• Tomancak, P, Beaton, A, Weiszmann, R, Kwan, E, Shu, S, Lewis, SE, Richards, S, Ashburner, M, Hartenstein, V, Celniker, SE, Rubin, GM. 2002. Systematic determination of patterns of gene expression during Drosophila embryogenesis. Genome Biol, 3:RESEARCH0088.
   Google Scholar
• Ugarte G, O'Day PM, Bacigalupo J, Vergara C. A ClC2-like chloride conductance in Drosophila photoreceptors. Pumps, transporters and ion channels, FV Sepúlveda, F Bezanilla. Kluwer Academic/Plenum Publishers, New York 2005; 157–164
   Google Scholar
• Varela D, Niemeyer MI, Cid LP, Sepúlveda FV. Effect of an N-terminus deletion on voltage-dependent gating of ClC-2 chloride channel. J Physiol (London) 2002; 544: 363–372
   Google Scholar
• Walz W. Chloride/anion channels in glial cell membranes. Glia 2002; 40: 1–10
   Google Scholar
• Wang J, Kean L, Yang J, Allan AK, Davies SA, Herzyk P, Dow JA. Function-informed transcriptome analysis of Drosophila renal tubule. Genome Biol 2004; 5: R69
   Web of Science ®Google Scholar
• Yandell M, Bailey AM, Misra S, Shu S, Wiel C, Evans-Holm M, Celniker SE, Rubin GM. A computational and experimental approach to validating annotations and gene predictions in the Drosophila melanogaster genome. Proc Natl Acad Sci USA 2005; 102: 1566–1571
   Google Scholar
• Yoshihara M, Ensminger AW, Littleton JT. Neurobiology and the Drosophila genome. Funct Integr Genomics 2001; 1: 235–240
   Google Scholar
• Zúñiga L, Niemeyer MI, Cárdenas L, Cid LP, Sepúlveda FV. Abolition of gating in ClC-2 by a double mutation affecting pore and CBS domains. J Physiol (London) 2005; 565P: PC80
   Google Scholar