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Research Article

Overview: Using Mode of Action and Life Stage Information to Evaluate the Human Relevance of Animal Toxicity Data

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Pages 663-672 | Published online: 10 Oct 2008

REFERENCES

  • Cohen S. M., Klaunig J., Meek M. E., Hill R. N., Pastoor T., Lehman-McKeeman L., Bucher J., Longfellow D. G., Seed J., Dellarco V., Fenner-Crisp P. A., Patton D. Evaluating the human relevance of chemically induced animal tumors. Toxicol. Sci. 2004; 78: 181–186, [PUBMED], [INFOTRIEVE], [CSA]
  • Meek M. E., Bucher J. R., Cohen S. M., DeMarco V., Hill R. N., Lehman-McKeeman L. D., Longfellow D. G., Pastoor T., Seed J., Patton D. E. A framework for human relevance analysis of information on carcinogenic modes of action. Crit. Rev. Toxicol. 2003; 33: 591–654, [PUBMED], [INFOTRIEVE], [CSA]
  • National Research Council (NRC). Science and Judgement in Risk Assessment. National Research Council, National Academy Press, Washington, DC 1994
  • Rice J. On the application of data on mode of action to carcinogenic risk assessment. Toxicol. Sci. 2004; 78: 175–177, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Sonich-Mullin C., Fielder R., Wiltse J., Baetcke K., Dempsey J., Fenner-Crisp P., Grant D., Hartley M., Knaap A., Kroese D., Mangelsdorf I., Meek E., Rice J. M., Younes M. IPCS conceptual framework for evaluating a MOA for chemical carcinogenesis. Regul. Toxicol. Pharmacol. 2001; 34: 146–152, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • U.S. Environmental Protection Agency. Guidelines for carcinogen risk assessment. Risk Assessment Forum. SAB review draft. U.S. Environmental Protection Agency, Washington, DC 1999, www.epa.gov/ncea/raf/crasab.htm.
  • U.S. Environmental Protection Agency. Guidelines for carcinogen risk assessment and supplemental guidelines for assessing susceptibility from early life exposure to carginogens. Risk Assessment Forum, U.S. Environmental Protection Agency, Washington, DC 2005; 70: 17765–17817, Feb. Regis. (April 7, 2005). www.epa.gov/cancerguidelines

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